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Items: 1 to 50 of 57

1.

C60 fullerenes selectively inhibit BKCa but not Kv channels in pulmonary artery smooth muscle cells.

Melnyk MI, Ivanova IV, Dryn DO, Prylutskyy YI, Hurmach VV, Platonov M, Al Kury LT, Ritter U, Soloviev AI, Zholos AV.

Nanomedicine. 2019 Apr 11;19:1-11. doi: 10.1016/j.nano.2019.03.018. [Epub ahead of print]

PMID:
30981819
2.

Curcuminoids and Novel Opportunities for the Treatment of Alzheimer's Disease: Which Molecules are Actually Effective?

Zholos AV, Moroz OF, Storozhuk MV.

Curr Mol Pharmacol. 2019;12(1):12-26. doi: 10.2174/1874467211666181012150847. Review.

PMID:
30318014
3.

TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells.

Luo J, Qian A, Oetjen LK, Yu W, Yang P, Feng J, Xie Z, Liu S, Yin S, Dryn D, Cheng J, Riehl TE, Zholos AV, Stenson WF, Kim BS, Hu H.

Immunity. 2018 Jul 17;49(1):107-119.e4. doi: 10.1016/j.immuni.2018.04.021. Epub 2018 Jun 26.

PMID:
29958798
4.

Liposomal quercetin potentiates maxi-K channel openings in smooth muscles and restores its activity after oxidative stress.

Melnyk MI, Dryn DO, Al Kury LT, Zholos AV, Soloviev AI.

J Liposome Res. 2019 Mar;29(1):94-101. doi: 10.1080/08982104.2018.1458864. Epub 2018 Apr 19.

PMID:
29671361
5.

C60 fullerenes disrupt cellular signalling leading to TRPC4 and TRPC6 channels opening by the activation of muscarinic receptors and G-proteins in small intestinal smooth muscles.

Dryn DO, Melnyk MI, Al Kury LT, Prylutskyy YI, Ritter U, Zholos AV.

Cell Signal. 2018 Mar;43:40-46. doi: 10.1016/j.cellsig.2017.12.003. Epub 2017 Dec 11.

PMID:
29242169
6.

Sensory TRP channels contribute differentially to skin inflammation and persistent itch.

Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Yin S, Kim BS, Hu H.

Nat Commun. 2017 Oct 30;8(1):980. doi: 10.1038/s41467-017-01056-8.

7.

TRP Channels as Novel Targets for Endogenous Ligands: Focus on Endocannabinoids and Nociceptive Signalling.

Storozhuk MV, Zholos AV.

Curr Neuropharmacol. 2018 Jan 30;16(2):137-150. doi: 10.2174/1570159X15666170424120802. Review.

8.

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles.

McGahon MK, Fernández JA, Dash DP, McKee J, Simpson DA, Zholos AV, McGeown JG, Curtis TM.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5637-5647. doi: 10.1167/iovs.16-20279.

PMID:
27784066
9.

Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition.

Melanaphy D, Johnson CD, Kustov MV, Watson CA, Borysova L, Burdyga TV, Zholos AV.

Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1416-H1430. doi: 10.1152/ajpheart.00222.2015. Epub 2016 Oct 7.

10.

Functional and Modeling Studies of the Transmembrane Region of the TRPM8 Channel.

Bidaux G, Sgobba M, Lemonnier L, Borowiec AS, Noyer L, Jovanovic S, Zholos AV, Haider S.

Biophys J. 2015 Nov 3;109(9):1840-51. doi: 10.1016/j.bpj.2015.09.027.

11.
12.

Functional and pharmacological characterization of volume-regulated anion channels in human normal and cystic fibrosis bronchial and nasal epithelial cells.

Stott JB, deCourcey F, Ennis M, Zholos AV.

Eur J Pharmacol. 2014 Oct 5;740:183-91. doi: 10.1016/j.ejphar.2014.07.007. Epub 2014 Jul 14.

PMID:
25034811
13.

TRPC5.

Zholos AV.

Handb Exp Pharmacol. 2014;222:129-56. doi: 10.1007/978-3-642-54215-2_6. Review.

PMID:
24756705
14.

TRP channels in vascular disorders.

Zholos AV, Curtis TM.

Curr Top Med Chem. 2013;13(3):295-309. Review.

PMID:
23432062
15.

Development of primary human nasal epithelial cell cultures for the study of cystic fibrosis pathophysiology.

de Courcey F, Zholos AV, Atherton-Watson H, Williams MT, Canning P, Danahay HL, Elborn JS, Ennis M.

Am J Physiol Cell Physiol. 2012 Dec 1;303(11):C1173-9. doi: 10.1152/ajpcell.00384.2011. Epub 2012 Sep 26.

16.

Studying Endogenous TRP Channels in Visceral and Vascular Smooth Muscles.

Zholos AV.

In: Zhu MX, editor. TRP Channels. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9.

17.

Short isoforms of the cold receptor TRPM8 inhibit channel gating by mimicking heat action rather than chemical inhibitors.

Fernández JA, Skryma R, Bidaux G, Magleby KL, Scholfield CN, McGeown JG, Prevarskaya N, Zholos AV.

J Biol Chem. 2012 Jan 27;287(5):2963-70. doi: 10.1074/jbc.M111.272823. Epub 2011 Nov 28.

18.

Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.

Miller M, Shi J, Zhu Y, Kustov M, Tian JB, Stevens A, Wu M, Xu J, Long S, Yang P, Zholos AV, Salovich JM, Weaver CD, Hopkins CR, Lindsley CW, McManus O, Li M, Zhu MX.

J Biol Chem. 2011 Sep 23;286(38):33436-46. doi: 10.1074/jbc.M111.274167. Epub 2011 Jul 27.

19.

Voltage- and cold-dependent gating of single TRPM8 ion channels.

Fernández JA, Skryma R, Bidaux G, Magleby KL, Scholfield CN, McGeown JG, Prevarskaya N, Zholos AV.

J Gen Physiol. 2011 Feb;137(2):173-95. doi: 10.1085/jgp.201010498.

20.

Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats.

Kizub IV, Pavlova OO, Johnson CD, Soloviev AI, Zholos AV.

Br J Pharmacol. 2010 Apr;159(8):1724-31. doi: 10.1111/j.1476-5381.2010.00666.x. Epub 2010 Mar 9.

21.

Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.

Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V.

Gastroenterology. 2009 Oct;137(4):1415-24. doi: 10.1053/j.gastro.2009.06.046. Epub 2009 Jun 21.

22.

Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone.

Johnson CD, Melanaphy D, Purse A, Stokesberry SA, Dickson P, Zholos AV.

Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1868-77. doi: 10.1152/ajpheart.01112.2008. Epub 2009 Apr 10.

23.

Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate.

Otsuguro K, Tang J, Tang Y, Xiao R, Freichel M, Tsvilovskyy V, Ito S, Flockerzi V, Zhu MX, Zholos AV.

J Biol Chem. 2008 Apr 11;283(15):10026-36. doi: 10.1074/jbc.M707306200. Epub 2008 Jan 29.

24.

Muscarinic receptor-activated cationic channels in murine ileal myocytes.

Dresviannikov AV, Bolton TB, Zholos AV.

Br J Pharmacol. 2006 Sep;149(2):179-87. Epub 2006 Aug 7.

26.

Effects of polyamines on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle myocytes.

Tsvilovskyy VV, Zholos AV, Bolton TB.

Br J Pharmacol. 2004 Dec;143(8):968-75. Epub 2004 Nov 22.

27.
29.
30.

Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.

Zholos AV, Tsytsyura YD, Gordienko DV, Tsvilovskyy VV, Bolton TB.

Br J Pharmacol. 2004 Jan;141(1):23-36. Epub 2003 Dec 8.

31.

Potential synergy: voltage-driven steps in receptor-G protein coupling and beyond.

Bolton TB, Zholos AV.

Sci STKE. 2003 Nov 25;2003(210):pe52. Review.

PMID:
14645810
32.

Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.

Yan HD, Okamoto H, Unno T, Tsytsyura YD, Prestwich SA, Komori S, Zholos AV, Bolton TB.

Br J Pharmacol. 2003 Jun;139(3):605-15.

33.

Sodium conductance in cultured myenteric AH-type neurons from guinea-pig small intestine.

Zholos AV, Baidan LV, Wood JD.

Auton Neurosci. 2002 Mar 18;96(2):93-102.

PMID:
11958482
34.

Membrane currents in cultured human intestinal smooth muscle cells.

Zholos AV, Fenech CJ, Prestwich SA, Bolton TB.

J Physiol. 2000 Nov 1;528(Pt 3):521-37.

35.

Voltage-dependent inhibition of the muscarinic cationic current in guinea-pig ileal cells by SK&F 96365.

Zholos AV, Tsytsyura YD, Philyppov IB, Shuba MF, Bolton TB.

Br J Pharmacol. 2000 Feb;129(4):695-702.

36.

Membrane ion channels as physiological targets for local Ca2+ signalling.

Gordienko DV, Zholos AV, Bolton TB.

J Microsc. 1999 Dec;196(Pt 3):305-16.

37.

Excitation-contraction coupling in gastrointestinal and other smooth muscles.

Bolton TB, Prestwich SA, Zholos AV, Gordienko DV.

Annu Rev Physiol. 1999;61:85-115. Review.

PMID:
10099683
38.

Potassium channels of myenteric neurons in guinea-pig small intestine.

Zholos AV, Baidan LV, Starodub AM, Wood JD.

Neuroscience. 1999 Mar;89(2):603-18.

PMID:
10077339
39.

Muscarinic cation current and suppression of Ca2+ current in guinea pig ileal smooth muscle cells.

Pucovský V, Zholos AV, Bolton TB.

Eur J Pharmacol. 1998 Apr 10;346(2-3):323-30.

PMID:
9652376
40.
41.

Effects of protons on muscarinic receptor cationic current in single visceral smooth muscle cells.

Zholos AV, Bolton TB.

Am J Physiol. 1997 Feb;272(2 Pt 1):G215-23.

PMID:
9124344
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