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miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease.

Long JK, Dai W, Zheng YW, Zhao SP.

Mol Med. 2019 Jun 13;25(1):26. doi: 10.1186/s10020-019-0085-2.


circZFR promotes cell proliferation and migration by regulating miR-511/AKT1 axis in hepatocellular carcinoma.

Yang X, Liu L, Zou H, Zheng YW, Wang KP.

Dig Liver Dis. 2019 May 27. pii: S1590-8658(19)30552-3. doi: 10.1016/j.dld.2019.04.012. [Epub ahead of print]


Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation.

Liu LP, Li YM, Guo NN, Li S, Ma X, Zhang YX, Gao Y, Huang JL, Zheng DX, Wang LY, Xu H, Hui L, Zheng YW.

Cell Rep. 2019 Apr 9;27(2):455-466.e5. doi: 10.1016/j.celrep.2019.03.046.


Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation.

Zhao YZ, ZhuGe DL, Tong MQ, Lin MT, Zheng YW, Jiang X, Yang WG, Yao Q, Xiang Q, Li XK, Xu HL.

J Control Release. 2019 Apr 10;299:90-106. doi: 10.1016/j.jconrel.2019.02.034. Epub 2019 Feb 23.


PRDM16 functions as a suppressor of lung adenocarcinoma metastasis.

Fei LR, Huang WJ, Wang Y, Lei L, Li ZH, Zheng YW, Wang Z, Yang MQ, Liu CC, Xu HT.

J Exp Clin Cancer Res. 2019 Jan 25;38(1):35. doi: 10.1186/s13046-019-1042-1.


Functional prediction and characterization of Dip2 gene in mice.

Ma J, Chen L, He XX, Wang YJ, Yu HL, He ZX, Zhang LQ, Zheng YW, Zhu XJ.

Cell Biol Int. 2019 Apr;43(4):421-428. doi: 10.1002/cbin.11106. Epub 2019 Feb 19.


Portal hypertension predicts short-term and long-term outcomes after hepatectomy in hepatocellular carcinoma patients.

Zheng YW, Wang KP, Zhou JJ, Zhang ZQ, Xiong L, Wen Y, Zou H.

Scand J Gastroenterol. 2018 Dec;53(12):1562-1568. doi: 10.1080/00365521.2018.1538386. Epub 2018 Dec 20.


Overexpression of Nemo-like kinase promotes the proliferation and invasion of lung cancer cells and indicates poor prognosis.

Lei L, Wang Y, Zheng YW, Fei LR, Shen HY, Li ZH, Huang WJ, Yu JH, Xu HT.

Curr Cancer Drug Targets. 2018 Nov 19. doi: 10.2174/1568009618666181119150521. [Epub ahead of print]


Photodynamic therapy for middle-advanced stage upper gastrointestinal carcinomas: A systematic review and meta-analysis.

Chen B, Xiong L, Chen WD, Zhao XH, He J, Zheng YW, Kong FH, Liu X, Zhang ZJ, Miao XY.

World J Clin Cases. 2018 Nov 6;6(13):650-658. doi: 10.12998/wjcc.v6.i13.650.


MicroRNA-200a Affects the Proliferation of Airway Smooth Muscle Cells and Airway Remodeling by Targeting FOXC1 via the PI3K/AKT Signaling Pathway in Ovalbumin-Induced Asthmatic Mice.

Liu Y, Miao Y, Gao X, Wang YY, Wang H, Zheng YW, Zhao ZY.

Cell Physiol Biochem. 2018;50(6):2365-2389. doi: 10.1159/000495097. Epub 2018 Nov 13.


Development of Individualized Induced Pluripotent Stem Cells From Fibroblasts of Keloid Lesions in Patients.

Zhang YX, Liu LP, Li M, Huang JL, Xu H, Chen XD, Zhu WY, Cai YP, Guo NN, Chen ZQ, Zheng YW, Li YM.

Transplant Proc. 2018 Nov;50(9):2868-2871. doi: 10.1016/j.transproceed.2018.04.008. Epub 2018 Apr 11.


A Multiple-Cell Microenvironment in a 3-Dimensional System Enhances Direct Cellular Reprogramming Into Hepatic Organoids.

Wang LY, Liu LP, Ge JY, Yuan YY, Sun LL, Xu H, Huang PY, Hui LJ, Isoda H, Ohkohchi N, Li YM, Zheng YW.

Transplant Proc. 2018 Nov;50(9):2864-2867. doi: 10.1016/j.transproceed.2018.03.076. Epub 2018 Mar 15. Erratum in: Transplant Proc. 2018 Dec;50(10):4102.


Recapitulation of hepatitis B virus-host interactions in liver organoids from human induced pluripotent stem cells.

Nie YZ, Zheng YW, Miyakawa K, Murata S, Zhang RR, Sekine K, Ueno Y, Takebe T, Wakita T, Ryo A, Taniguchi H.

EBioMedicine. 2018 Sep;35:114-123. doi: 10.1016/j.ebiom.2018.08.014. Epub 2018 Aug 16.


Homing of ICG-loaded liposome inlaid with tumor cellular membrane to the homologous xenografts glioma eradicates the primary focus and prevents lung metastases through phototherapy.

Xu HL, Shen BX, Lin MT, Tong MQ, Zheng YW, Jiang X, Yang WG, Yuan JD, Yao Q, Zhao YZ.

Biomater Sci. 2018 Aug 21;6(9):2410-2425. doi: 10.1039/c8bm00604k.


Odd-skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and β-catenin.

Wang Y, Lei L, Zheng YW, Zhang L, Li ZH, Shen HY, Jiang GY, Zhang XP, Wang EH, Xu HT.

Cancer Sci. 2018 Jun;109(6):1799-1810. doi: 10.1111/cas.13614. Epub 2018 May 23.


A rapid fluorogenic GPCR-β-arrestin interaction assay.

Zhang Q, Zheng YW, Coughlin SR, Shu X.

Protein Sci. 2018 Apr;27(4):874-879. doi: 10.1002/pro.3385. Epub 2018 Feb 23.


Comprehensive Profiling of Fecal Metabolome of Mice by Integrated Chemical Isotope Labeling-Mass Spectrometry Analysis.

Yuan BF, Zhu QF, Guo N, Zheng SJ, Wang YL, Wang J, Xu J, Liu SJ, He K, Hu T, Zheng YW, Xu FQ, Feng YQ.

Anal Chem. 2018 Mar 6;90(5):3512-3520. doi: 10.1021/acs.analchem.7b05355. Epub 2018 Feb 14.


Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells.

Zhang RR, Zheng YW, Li B, Nie YZ, Ueno Y, Tsuchida T, Taniguchi H.

Stem Cell Res Ther. 2018 Feb 5;9(1):29. doi: 10.1186/s13287-017-0747-3.


Silk fibroin nanoparticles dyeing indocyanine green for imaging-guided photo-thermal therapy of glioblastoma.

Xu HL, ZhuGe DL, Chen PP, Tong MQ, Lin MT, Jiang X, Zheng YW, Chen B, Li XK, Zhao YZ.

Drug Deliv. 2018 Nov;25(1):364-375. doi: 10.1080/10717544.2018.1428244.


Human liver organoids generated with single donor-derived multiple cells rescue mice from acute liver failure.

Nie YZ, Zheng YW, Ogawa M, Miyagi E, Taniguchi H.

Stem Cell Res Ther. 2018 Jan 10;9(1):5. doi: 10.1186/s13287-017-0749-1.


Tissue-type plasminogen activator contributes to remodeling of the rat ductus arteriosus.

Saito J, Yokoyama U, Nicho N, Zheng YW, Ichikawa Y, Ito S, Umemura M, Fujita T, Ito S, Taniguchi H, Asou T, Masuda M, Ishikawa Y.

PLoS One. 2018 Jan 5;13(1):e0190871. doi: 10.1371/journal.pone.0190871. eCollection 2018.


Thyroid cancer 1 (C8orf4) shows high expression, no mutation and reduced methylation level in lung cancers, and its expression correlates with β-catenin and DNMT1 expression and poor prognosis.

Zheng YW, Zhang L, Wang Y, Chen SY, Lei L, Tang N, Yang DL, Bai LL, Zhang XP, Jiang GY, Yang LH, Xu HT, Li QC, Qiu XS, Wang EH.

Oncotarget. 2017 Apr 6;8(38):62880-62890. doi: 10.18632/oncotarget.16877. eCollection 2017 Sep 8.


Determination of the physiological and pathological roles of E2F3 in adult tissues.

Gamper I, Burkhart DL, Bywater MJ, Garcia D, Wilson CH, Kreuzaler PA, Arends MJ, Zheng YW, Perfetto A, Littlewood TD, Evan GI.

Sci Rep. 2017 Aug 30;7(1):9932. doi: 10.1038/s41598-017-09494-6.


Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species.

Nakayama K, Murata S, Ito H, Iwasaki K, Villareal MO, Zheng YW, Matsui H, Isoda H, Ohkohchi N.

Oncol Lett. 2017 Aug;14(2):2015-2024. doi: 10.3892/ol.2017.6370. Epub 2017 Jun 12.


[Identification of a new 3.8kb deletional α thalassemia and detection of the deletion fragment].

Huang G, Zheng YW, Wang JJ, Wu J, Liu SN.

Nan Fang Yi Ke Da Xue Xue Bao. 2017 Jul 20;37(7):997-1000. Chinese.


Benzene C-H Etherification via Photocatalytic Hydrogen-Evolution Cross-Coupling Reaction.

Zheng YW, Ye P, Chen B, Meng QY, Feng K, Wang W, Wu LZ, Tung CH.

Org Lett. 2017 May 5;19(9):2206-2209. doi: 10.1021/acs.orglett.7b00463. Epub 2017 Apr 14.


Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.

Koike H, Zhang RR, Ueno Y, Sekine K, Zheng YW, Takebe T, Taniguchi H.

Development. 2017 Mar 15;144(6):1018-1024. doi: 10.1242/dev.143032. Epub 2017 Feb 20.


[Modification of DNA methylation in leukemia development].

Gao A, Zheng YW, Cheng T.

Zhonghua Xue Ye Xue Za Zhi. 2016 Nov 14;37(11):1003-1007. doi: 10.3760/cma.j.issn.0253-2727.2016.11.017. Chinese. No abstract available.


Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer.

Iwasaki K, Zheng YW, Murata S, Ito H, Nakayama K, Kurokawa T, Sano N, Nowatari T, Villareal MO, Nagano YN, Isoda H, Matsui H, Ohkohchi N.

World J Gastroenterol. 2016 Nov 28;22(44):9765-9774.


Effect of Long Noncoding RNA H19 Overexpression on Intestinal Barrier Function and Its Potential Role in the Pathogenesis of Ulcerative Colitis.

Chen SW, Wang PY, Liu YC, Sun L, Zhu J, Zuo S, Ma J, Li TY, Zhang JL, Chen GW, Wang X, Zhu QR, Zheng YW, Chen ZY, Yao ZH, Pan YS.

Inflamm Bowel Dis. 2016 Nov;22(11):2582-2592.


Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells.

Zhang RR, Zheng YW, Taniguchi H.

J Vis Exp. 2016 Aug 29;(114). doi: 10.3791/54167.


Photocatalytic Hydrogen-Evolution Cross-Couplings: Benzene C-H Amination and Hydroxylation.

Zheng YW, Chen B, Ye P, Feng K, Wang W, Meng QY, Wu LZ, Tung CH.

J Am Chem Soc. 2016 Aug 17;138(32):10080-3. doi: 10.1021/jacs.6b05498. Epub 2016 Aug 3.


[Diagnostic performance of intraoperative sentinel lymph node touch imprint cytology in 108 cases of invasive lobular carcinoma with various clinicopathologic characteristics].

Wang YL, Gao LL, Chen Y, Gui X, Yang WT, Shen XX, Zheng YW, Zhang H, Feng LQ, Wang LF, Ping B.

Zhonghua Bing Li Xue Za Zhi. 2016 Jul 8;45(7):472-3. doi: 10.3760/cma.j.issn.0529-5807.2016.07.009. Chinese. No abstract available.


High correlation of specific IgE sensitization between birch pollen, soy and apple allergens indicates pollen-food allergy syndrome among birch pollen allergic patients in northern China.

Hao GD, Zheng YW, Wang ZX, Kong XA, Song ZJ, Lai XX, Spangfort MD.

J Zhejiang Univ Sci B. 2016 May;17(5):399-404. doi: 10.1631/jzus.B1500279.


Caveolae Restrict Tiger Frog Virus Release in HepG2 cells and Caveolae-Associated Proteins Incorporated into Virus Particles.

He J, Zheng YW, Lin YF, Mi S, Qin XW, Weng SP, He JG, Guo CJ.

Sci Rep. 2016 Feb 18;6:21663. doi: 10.1038/srep21663.


Novel functions of platelets in the liver.

Kurokawa T, Zheng YW, Ohkohchi N.

J Gastroenterol Hepatol. 2016 Apr;31(4):745-51. doi: 10.1111/jgh.13244. Review.


Indoor Allergen Levels and Household Distributions in Nine Cities Across China.

Zheng YW, Lai XX, Zhao DY, Zhang CQ, Chen JJ, Zhang L, Wei QY, Chen S, Liu EM, Norback D, Gjesing B, Zhong NS, Spangfort DM.

Biomed Environ Sci. 2015 Oct;28(10):709-17. doi: 10.3967/bes2015.101.


Activation of CH Bonds through Oxidant-Free Photoredox Catalysis: Cross-Coupling Hydrogen-Evolution Transformation of Isochromans and β-Keto Esters.

Xiang M, Meng QY, Li JX, Zheng YW, Ye C, Li ZJ, Chen B, Tung CH, Wu LZ.

Chemistry. 2015 Dec 7;21(50):18080-4. doi: 10.1002/chem.201503361. Epub 2015 Oct 30.


Protecting liver sinusoidal endothelial cells suppresses apoptosis in acute liver damage.

Tanoi T, Tamura T, Sano N, Nakayama K, Fukunaga K, Zheng YW, Akhter A, Sakurai Y, Hayashi Y, Harashima H, Ohkohchi N.

Hepatol Res. 2016 Jun;46(7):697-706. doi: 10.1111/hepr.12607. Epub 2015 Nov 12.


The Eltrombopag antitumor effect on hepatocellular carcinoma.

Kurokawa T, Murata S, Zheng YW, Iwasaki K, Kohno K, Fukunaga K, Ohkohchi N.

Int J Oncol. 2015 Nov;47(5):1696-702. doi: 10.3892/ijo.2015.3180. Epub 2015 Sep 23.


Validation of a Mandarin Chinese version of the pelvic organ prolapse/urinary incontinence sexual questionnaire IUGA-revised (PISQ-IR).

Wang H, Lau HH, Hung MJ, Huang WC, Zheng YW, Su TH.

Int Urogynecol J. 2015 Nov;26(11):1695-700. doi: 10.1007/s00192-015-2744-3. Epub 2015 May 31.


[Macrophage inflammatory protein-1α promotes the growth of acute myeloid leukemia cells].

Lu P, Wang YJ, Zheng YW, Dong F, Pang YK, Cheng H, Yuan WP, Cheng T, Hao S.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2015 Apr;23(2):306-11. doi: 10.7534/j.issn.1009-2137.2015.02.003. Chinese.


Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.

Zhang RR, Zheng YW, Li B, Tsuchida T, Ueno Y, Nie YZ, Taniguchi H.

Stem Cell Res Ther. 2015 Mar 26;6:49. doi: 10.1186/s13287-015-0038-9.


Acyclic retinoid induces differentiation and apoptosis of murine hepatic stem cells.

Guan HB, Nie YZ, Zheng YW, Takiguchi K, Yu HW, Zhang RR, Li B, Tsuchida T, Taniguchi H.

Stem Cell Res Ther. 2015 Mar 26;6:51. doi: 10.1186/s13287-015-0046-9.


Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture.

Zhang RR, Takebe T, Miyazaki L, Takayama M, Koike H, Kimura M, Enomura M, Zheng YW, Sekine K, Taniguchi H.

Methods Mol Biol. 2014;1210:131-41. doi: 10.1007/978-1-4939-1435-7_10.


Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver.

Koike H, Ouchi R, Ueno Y, Nakata S, Obana Y, Sekine K, Zheng YW, Takebe T, Isono K, Koseki H, Taniguchi H.

PLoS One. 2014 Aug 25;9(8):e104776. doi: 10.1371/journal.pone.0104776. eCollection 2014.


Prognostic significance of CD44 variant 2 upregulation in colorectal cancer.

Ozawa M, Ichikawa Y, Zheng YW, Oshima T, Miyata H, Nakazawa K, Guan HB, Shiozawa M, Akaike M, Watanabe K, Ota M, Fujii S, Kunisaki C, Ishikawa T, Tanaka K, Akiyama H, Endo I, Taniguchi H.

Br J Cancer. 2014 Jul 15;111(2):365-74. doi: 10.1038/bjc.2014.253. Epub 2014 Jun 12.


Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing.

Yu SC, Chan KC, Zheng YW, Jiang P, Liao GJ, Sun H, Akolekar R, Leung TY, Go AT, van Vugt JM, Minekawa R, Oudejans CB, Nicolaides KH, Chiu RW, Lo YM.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8583-8. doi: 10.1073/pnas.1406103111. Epub 2014 May 19.


Tropism of cancer stem cells to a specific distant organ.

Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H.

In Vivo. 2014 May-Jun;28(3):361-5.


Evidence of a sophisticatedly heterogeneous population of human umbilical vein endothelial cells.

Zheng YW, Nie YZ, Tsuchida T, Zhang RR, Aoki K, Sekine K, Ogawa M, Takebe T, Ueno Y, Sakakibara H, Hirahara F, Taniguchi H.

Transplant Proc. 2014 May;46(4):1251-3. doi: 10.1016/j.transproceed.2013.11.077.


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