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Items: 1 to 50 of 280

1.

Downregulation of PRMT1 promotes the senescence and migration of a non-MYCN amplified neuroblastoma SK-N-SH cells.

Lee YJ, Chang WW, Chang CP, Liu TY, Chuang CY, Qian K, Zheng YG, Li C.

Sci Rep. 2019 Feb 11;9(1):1771. doi: 10.1038/s41598-018-38394-6.

2.

A rapid throughput assay for screening (R)-2-(4-hydroxyphenoxy)propionic acid producing microbes.

Hu HF, Zhou HY, Wang MX, Wang YS, Xue YP, Zheng YG.

J Microbiol Methods. 2019 Jan 29;158:44-51. doi: 10.1016/j.mimet.2019.01.015. [Epub ahead of print]

PMID:
30703447
3.

Statistical medium optimization and DO-STAT fed-batch fermentation for enhanced production of tyrosine phenol lyase in recombinant Escherichia coli.

Tang XL, Wang ZC, Yang J, Zheng RC, Zheng YG.

Prep Biochem Biotechnol. 2019 Jan 28:1-10. doi: 10.1080/10826068.2018.1541808. [Epub ahead of print]

PMID:
30689497
4.

Bisubstrate inhibitors to target histone acetyltransferase 1.

Ngo L, Brown T, Zheng YG.

Chem Biol Drug Des. 2019 Jan 14. doi: 10.1111/cbdd.13476. [Epub ahead of print]

PMID:
30637990
5.

Molecular modification of a halohydrin dehalogenase for kinetic regulation to synthesize optically pure (S)-epichlorohydrin.

Zhang XJ, Deng HZ, Liu N, Gong YC, Liu ZQ, Zheng YG.

Bioresour Technol. 2019 Mar;276:154-160. doi: 10.1016/j.biortech.2018.12.103. Epub 2018 Dec 27.

PMID:
30623870
6.

Structure-Based Engineering of Amidase from Pantoea sp. for Efficient 2-Chloronicotinic Acid Biosynthesis.

Tang XL, Jin JQ, Wu ZM, Jin LQ, Zheng RC, Zheng YG.

Appl Environ Microbiol. 2018 Dec 21. pii: AEM.02471-18. doi: 10.1128/AEM.02471-18. [Epub ahead of print]

PMID:
30578259
7.

Continuous production of aprepitant chiral intermediate by immobilized amidase in a packed bed bioreactor.

Lin CP, Wu ZM, Tang XL, Hao CL, Zheng RC, Zheng YG.

Bioresour Technol. 2019 Feb;274:371-378. doi: 10.1016/j.biortech.2018.12.006. Epub 2018 Dec 3.

PMID:
30544042
8.

Application of metabolomics in toxicity evaluation of traditional Chinese medicines.

Duan L, Guo L, Wang L, Yin Q, Zhang CM, Zheng YG, Liu EH.

Chin Med. 2018 Dec 4;13:60. doi: 10.1186/s13020-018-0218-5. eCollection 2018. Review.

9.

Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized Talaromyces thermophilus Lipase.

Ding X, Tang XL, Zheng RC, Zheng YG.

Biomed Res Int. 2018 Nov 1;2018:6192059. doi: 10.1155/2018/6192059. eCollection 2018.

10.

Highly efficient conversion of 1-cyanocycloalkaneacetonitrile using a "super nitrilase mutant".

Xu Z, Xiong N, Zou SP, Liu YX, Liu ZQ, Xue YP, Zheng YG.

Bioprocess Biosyst Eng. 2018 Nov 28. doi: 10.1007/s00449-018-2049-2. [Epub ahead of print]

PMID:
30488321
11.

Colorimetric assay for active biomass quantification of Fusarium fujikuroi.

Cen YK, Lin JG, Wang JY, Liu ZQ, Zheng YG.

J Microbiol Methods. 2018 Dec;155:37-41. doi: 10.1016/j.mimet.2018.11.009. Epub 2018 Nov 12.

PMID:
30439464
12.

Enhanced Production of 6-(N-Hydroxyethyl)-Amino-6-Deoxy-α-L-Sorbofuranose by Immobilized Gluconobacter oxydanson Corn Stover with a pH Control Strategy in a Bubble Column Bioreactor.

Hu ZC, Bu JL, Wang RY, Ke X, Zheng YG.

Appl Biochem Biotechnol. 2018 Nov 15. doi: 10.1007/s12010-018-2924-y. [Epub ahead of print]

PMID:
30430346
13.

Identification and engineering of the key residues at the crevice-like binding site of lipases responsible for activity and substrate specificity.

Ding X, Tang XL, Zheng RC, Zheng YG.

Biotechnol Lett. 2019 Jan;41(1):137-146. doi: 10.1007/s10529-018-2620-6. Epub 2018 Nov 3.

PMID:
30392017
14.

[Quality evaluation of Taraxaci Herba based on fingerprint analysis and quantitative analysis of multi-components].

Liu AP, Gou LX, Xue ZJ, Zheng YG, Guo L.

Zhongguo Zhong Yao Za Zhi. 2018 Sep;43(18):3715-3721. doi: 10.19540/j.cnki.cjcmm.2018.0103. Chinese.

PMID:
30384538
15.

Defining the epigenetic status of blood cells using a cyanine-based fluorescent probe for PRMT1.

Su H, Sun CW, Liu SM, He X, Hu H, Pawlik KM, Townes TM, Han X, Klug CA, Henary M, Chen Y, Li L, Zheng YG, Zhao X.

Blood Adv. 2018 Nov 13;2(21):2829-2836. doi: 10.1182/bloodadvances.2018020727.

16.

Systematic Analysis of Bottlenecks in a Multibranched and Multilevel Regulated Pathway: The Molecular Fundamentals of l-Methionine Biosynthesis in Escherichia coli.

Huang JF, Shen ZY, Mao QL, Zhang XM, Zhang B, Wu JS, Liu ZQ, Zheng YG.

ACS Synth Biol. 2018 Nov 16;7(11):2577-2589. doi: 10.1021/acssynbio.8b00249. Epub 2018 Oct 17.

PMID:
30274509
17.

Comparison of Artemisiae argyi Folium and Artemisiae lavandulaefoliae Folium by simultaneous determination of multi-components with single reference standard method and chemometric analysis.

Guo L, Zhang D, Xue ZJ, Jiao Q, Liu AP, Zheng YG, Liu EH, Duan L.

Phytochem Anal. 2019 Jan;30(1):14-25. doi: 10.1002/pca.2786. Epub 2018 Sep 5.

PMID:
30252165
18.

Mechanisms and Inhibitors of Histone Arginine Methylation.

Fulton MD, Brown T, Zheng YG.

Chem Rec. 2018 Dec;18(12):1792-1807. doi: 10.1002/tcr.201800082. Epub 2018 Sep 19. Review.

PMID:
30230223
19.

Novel strategy of sirolimus plus thymalfasin and huaier granule on tumor recurrence of hepatocellular carcinoma beyond the UCSF criteria following liver transplantation: A single center experience.

Zhou L, Pan LC, Zheng YG, Du GS, Fu XQ, Zhu ZD, Song JY, Liu ZJ, Su XZ, Chen W, Zheng DH, Suo LL, Yang SZ.

Oncol Lett. 2018 Oct;16(4):4407-4417. doi: 10.3892/ol.2018.9226. Epub 2018 Jul 27.

20.

An efficient colorimetric high-throughput screening method for synthetic activity of tyrosine phenol-lyase.

Tang XL, Suo H, Zheng RC, Zheng YG.

Anal Biochem. 2018 Nov 1;560:7-11. doi: 10.1016/j.ab.2018.08.026. Epub 2018 Aug 31.

PMID:
30176231
21.

Efficient Biosynthesis of Xylitol from Xylose by Coexpression of Xylose Reductase and Glucose Dehydrogenase in Escherichia coli.

Jin LQ, Xu W, Yang B, Liu ZQ, Zheng YG.

Appl Biochem Biotechnol. 2018 Sep 3. doi: 10.1007/s12010-018-2878-0. [Epub ahead of print]

PMID:
30175383
22.

Lysine benzoylation is a histone mark regulated by SIRT2.

Huang H, Zhang D, Wang Y, Perez-Neut M, Han Z, Zheng YG, Hao Q, Zhao Y.

Nat Commun. 2018 Aug 28;9(1):3374. doi: 10.1038/s41467-018-05567-w.

23.

Efficacy and safety of oral targeted therapies in pulmonary arterial hypertension: a meta-analysis of randomized clinical trials.

Zheng YG, Ma H, Chen L, Jiang XM, Zhou L, Lin S, Chen SL.

Pulm Circ. 2018 Oct-Dec;8(4):2045894018798183. doi: 10.1177/2045894018798183. Epub 2018 Aug 20.

24.

Conjugation of Agrobacterium radiobacter epoxide hydrolase with ficoll: Catalytic, kinetic and thermodynamic analysis.

Zou SP, Xuan XL, Wang ZJ, Zheng YG.

Int J Biol Macromol. 2018 Nov;119:1098-1105. doi: 10.1016/j.ijbiomac.2018.08.029. Epub 2018 Aug 8.

PMID:
30098359
25.

Improvement of carbonyl reductase activity for the bioproduction of tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate.

Liu ZQ, Yin HH, Zhang XJ, Zhou R, Wang YM, Zheng YG.

Bioorg Chem. 2018 Oct;80:733-740. doi: 10.1016/j.bioorg.2018.07.025. Epub 2018 Jul 23.

PMID:
30077176
26.

Increased expression of long noncoding RNA LINC00961 suppresses glioma metastasis and correlates with favorable prognosis.

Lu XW, Xu N, Zheng YG, Li QX, Shi JS.

Eur Rev Med Pharmacol Sci. 2018 Aug;22(15):4917-4924. doi: 10.26355/eurrev_201808_15630.

27.

Metabolic engineering of E. coli for the production of O-succinyl-l-homoserine with high yield.

Huang JF, Zhang B, Shen ZY, Liu ZQ, Zheng YG.

3 Biotech. 2018 Jul;8(7):310. doi: 10.1007/s13205-018-1332-x. Epub 2018 Jul 9.

PMID:
30002999
28.

Efficient chemoenzymatic synthesis of (S)-α-amino-4-fluorobenzeneacetic acid using immobilized penicillin amidase.

Lin CP, Tang XL, Zheng RC, Zheng YG.

Bioorg Chem. 2018 Oct;80:174-179. doi: 10.1016/j.bioorg.2018.06.020. Epub 2018 Jun 15.

PMID:
29929078
29.

Process development for efficient biosynthesis of L-DOPA with recombinant Escherichia coli harboring tyrosine phenol lyase from Fusobacterium nucleatum.

Tang XL, Liu X, Suo H, Wang ZC, Zheng RC, Zheng YG.

Bioprocess Biosyst Eng. 2018 Sep;41(9):1347-1354. doi: 10.1007/s00449-018-1962-8. Epub 2018 Jun 5.

PMID:
29869726
30.

Species composition, functional and phylogenetic distances correlate with success of invasive Chromolaena odorata in an experimental test.

Zheng YL, Burns JH, Liao ZY, Li YP, Yang J, Chen YJ, Zhang JL, Zheng YG.

Ecol Lett. 2018 Aug;21(8):1211-1220. doi: 10.1111/ele.13090. Epub 2018 May 28.

PMID:
29808558
31.

Biosynthesis of chiral epichlorohydrin using an immobilized halohydrin dehalogenase in aqueous and non-aqueous phase.

Zhang XJ, Shi PX, Deng HZ, Wang XX, Liu ZQ, Zheng YG.

Bioresour Technol. 2018 Sep;263:483-490. doi: 10.1016/j.biortech.2018.05.027. Epub 2018 May 8.

PMID:
29775904
32.

A bioorthogonal turn-on fluorescent strategy for the detection of lysine acetyltransferase activity.

He M, Han Z, Qiao J, Ngo L, Xiong MP, Zheng YG.

Chem Commun (Camb). 2018 May 29;54(44):5594-5597. doi: 10.1039/c8cc02987c.

PMID:
29766153
33.

Significant improvement of the nitrilase activity by semi-rational protein engineering and its application in the production of iminodiacetic acid.

Liu ZQ, Lu MM, Zhang XH, Cheng F, Xu JM, Xue YP, Jin LQ, Wang YS, Zheng YG.

Int J Biol Macromol. 2018 Sep;116:563-571. doi: 10.1016/j.ijbiomac.2018.05.045. Epub 2018 May 10.

PMID:
29753012
34.

Biosynthesis of miglitol intermediate 6-(N-hydroxyethyl)-amino-6-deoxy-α-l-sorbofuranose by an improved d-sorbitol dehydrogenase from Gluconobacter oxydans.

Ke X, Wang NN, Yu PH, Lu YH, Hu ZC, Zheng YG.

3 Biotech. 2018 May;8(5):231. doi: 10.1007/s13205-018-1251-x. Epub 2018 Apr 28.

PMID:
29719773
35.

[Quality evaluation of Artemisiae Argyi Folium based on fingerprint analysis and quantitative analysis of multicomponents].

Guo L, Jiao Q, Zhang D, Liu AP, Wang Q, Zheng YG.

Zhongguo Zhong Yao Za Zhi. 2018 Mar;43(5):977-984. doi: 10.19540/j.cnki.cjcmm.2018.0029. Chinese.

PMID:
29676097
36.

Highly Efficient Deracemization of Racemic 2-Hydroxy Acids in a Three-Enzyme Co-Expression System Using a Novel Ketoacid Reductase.

Xue YP, Wang C, Wang DC, Liu ZQ, Zheng YG.

Appl Biochem Biotechnol. 2018 Nov;186(3):563-575. doi: 10.1007/s12010-018-2760-0. Epub 2018 Apr 20.

PMID:
29675666
37.

Whole cell immobilization of refractory glucose isomerase using tris(hydroxymethyl)phosphine as crosslinker for preparation of high fructose corn syrup at elevated temperature.

Jia DX, Wang T, Liu ZJ, Jin LQ, Li JJ, Liao CJ, Chen DS, Zheng YG.

J Biosci Bioeng. 2018 Aug;126(2):176-182. doi: 10.1016/j.jbiosc.2018.03.001. Epub 2018 Apr 5.

PMID:
29627319
38.

ReToAd: simple method for the rapid replacement of promoters to improve protein production.

Cheng F, Xiang C, Zhang XJ, Liu ZQ, Zheng YG.

Biotechnol Lett. 2018 Jun;40(6):957-964. doi: 10.1007/s10529-018-2541-4. Epub 2018 Apr 2.

PMID:
29611067
39.

Engineering the residues on "A" surface and C-terminal region to improve thermostability of nitrilase.

Xu Z, Cai T, Xiong N, Zou SP, Xue YP, Zheng YG.

Enzyme Microb Technol. 2018 Jun;113:52-58. doi: 10.1016/j.enzmictec.2018.03.001. Epub 2018 Mar 5.

PMID:
29602387
40.

Rate-limiting steps in the Saccharomyces cerevisiae ergosterol pathway: towards improved ergosta-5,7-dien-3β-ol accumulation by metabolic engineering.

Ma BX, Ke X, Tang XL, Zheng RC, Zheng YG.

World J Microbiol Biotechnol. 2018 Mar 28;34(4):55. doi: 10.1007/s11274-018-2440-9.

PMID:
29594560
41.

[Determination of six active ingredients in different parts of Belamcanda chinensis and Iris tectorum and their anti-inflammatory activity].

Bian Y, Liu MS, Zhang LY, Li GC, Feng JM, Liang X, Zheng YG, Wang J.

Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):119-122. doi: 10.19540/j.cnki.cjcmm.20171027.006. Chinese.

PMID:
29552821
42.

Detection of PRMT1 inhibitors with stopped flow fluorescence.

Qian K, Hu H, Xu H, Zheng YG.

Signal Transduct Target Ther. 2018 Mar 9;3:6. doi: 10.1038/s41392-018-0009-6. eCollection 2018.

43.

Biochemical characterization of a novel tyrosine phenol-lyase from Fusobacterium nucleatum for highly efficient biosynthesis of l-DOPA.

Zheng RC, Tang XL, Suo H, Feng LL, Liu X, Yang J, Zheng YG.

Enzyme Microb Technol. 2018 May;112:88-93. doi: 10.1016/j.enzmictec.2017.11.004. Epub 2017 Nov 14.

PMID:
29499786
44.

Engineering of Talaromyces thermophilus lipase by altering its crevice-like binding site for highly efficient biocatalytic synthesis of chiral intermediate of Pregablin.

Ding X, Zheng RC, Tang XL, Zheng YG.

Bioorg Chem. 2018 Apr;77:330-338. doi: 10.1016/j.bioorg.2018.01.018. Epub 2018 Jan 12.

PMID:
29421709
45.

Covalent immobilization of halohydrin dehalogenase for efficient synthesis of epichlorohydrin in an integrated bioreactor.

Zou SP, Gu K, Zheng YG.

Biotechnol Prog. 2018 May;34(3):784-792. doi: 10.1002/btpr.2617. Epub 2018 Feb 12.

PMID:
29388368
46.

Enzymatic asymmetric synthesis of chiral amino acids.

Xue YP, Cao CH, Zheng YG.

Chem Soc Rev. 2018 Feb 19;47(4):1516-1561. doi: 10.1039/c7cs00253j. Review.

PMID:
29362736
47.

An ornithine ω-aminotransferase required for growth in the absence of exogenous proline in the archaeon Thermococcus kodakarensis.

Zheng RC, Hachisuka SI, Tomita H, Imanaka T, Zheng YG, Nishiyama M, Atomi H.

J Biol Chem. 2018 Mar 9;293(10):3625-3636. doi: 10.1074/jbc.RA117.001222. Epub 2018 Jan 19.

PMID:
29352105
48.

Sirolimus treatment for cirrhosis or hepatocellular carcinoma patients accompanied by psoriasis after liver transplantation: A single center experience.

Zhou L, Du GS, Pan LC, Zheng YG, Liu ZJ, Shi HD, Yang SZ, Shi XJ, Xuan M, Feng LK, Zhu ZD.

Oncol Lett. 2017 Dec;14(6):7817-7824. doi: 10.3892/ol.2017.7217. Epub 2017 Oct 18.

49.

Enhancement of Nucleoside Production in Hirsutella sinensis Based on Biosynthetic Pathway Analysis.

Liu ZQ, Zhang B, Lin S, Baker PJ, Chen MS, Xue YP, Wu H, Xu F, Yuan SJ, Teng Y, Wu LF, Zheng YG.

Biomed Res Int. 2017;2017:2520347. doi: 10.1155/2017/2520347. Epub 2017 Nov 29.

50.

Revealing the protein propionylation activity of the histone acetyltransferase MOF (males absent on the first).

Han Z, Wu H, Kim S, Yang X, Li Q, Huang H, Cai H, Bartlett MG, Dong A, Zeng H, Brown PJ, Yang XJ, Arrowsmith CH, Zhao Y, Zheng YG.

J Biol Chem. 2018 Mar 2;293(9):3410-3420. doi: 10.1074/jbc.RA117.000529. Epub 2018 Jan 10.

PMID:
29321206

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