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The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species.

Shefchek KA, Harris NL, Gargano M, Matentzoglu N, Unni D, Brush M, Keith D, Conlin T, Vasilevsky N, Zhang XA, Balhoff JP, Babb L, Bello SM, Blau H, Bradford Y, Carbon S, Carmody L, Chan LE, Cipriani V, Cuzick A, Rocca MD, Dunn N, Essaid S, Fey P, Grove C, Gourdine JP, Hamosh A, Harris M, Helbig I, Hoatlin M, Joachimiak M, Jupp S, Lett KB, Lewis SE, McNamara C, Pendlington ZM, Pilgrim C, Putman T, Ravanmehr V, Reese J, Riggs E, Robb S, Roncaglia P, Seager J, Segerdell E, Similuk M, Storm AL, Thaxon C, Thessen A, Jacobsen JOB, McMurry JA, Groza T, Köhler S, Smedley D, Robinson PN, Mungall CJ, Haendel MA, Munoz-Torres MC, Osumi-Sutherland D.

Nucleic Acids Res. 2019 Nov 8. pii: gkz997. doi: 10.1093/nar/gkz997. [Epub ahead of print]


Improved Efficiency in All-Small-Molecule Organic Solar Cells with Ternary Blend of Non-Fullerene Acceptor and Chlorinated and Non-Chlorinated Donors.

Ge J, Wei Q, Peng R, Zhou E, Yan T, Song W, Zhang W, Zhang XA, Jiang S, Ge Z.

ACS Appl Mater Interfaces. 2019 Nov 7. doi: 10.1021/acsami.9b16900. [Epub ahead of print]


Dynamics of an SLIR model with nonmonotone incidence rate and stochastic perturbation.

Zhang JH, Ren JL, Zhang XA.

Math Biosci Eng. 2019 Jun 14;16(5):5504-5530. doi: 10.3934/mbe.2019274.


Rickettsia japonica Infections in Humans, Xinyang, China, 2014-2017.

Li H, Zhang PH, Du J, Yang ZD, Cui N, Xing B, Zhang XA, Liu W.

Emerg Infect Dis. 2019 Sep;25(9):1719-1722. doi: 10.3201/eid2509.171421.


Immunosuppressive therapies adversely affect blood biochemical parameters in patients with inflammatory bowel disease: a meta-analysis.

Wang X, Wang G, Shang J, Pan H, Zhang XA, Zhou F.

J Int Med Res. 2019 Aug;47(8):3534-3549. doi: 10.1177/0300060519864800. Epub 2019 Jul 31. No abstract available.


Quadruply-labeled serum albumin as a biodegradable nanosensor for simultaneous fluorescence imaging of intracellular pH values, oxygen and temperature.

Zhang XA, Zhang W, Wang Q, Wang J, Ren G, Wang XD.

Mikrochim Acta. 2019 Jul 30;186(8):584. doi: 10.1007/s00604-019-3674-4.


[Dose-response Relationship of Dexmedetomidine Combined with Sufentail for Postoperative Intravenous Analgesia in Video-assisted Thoracoscopic Surgery].

Tan XL, Chen YY, Hu B, Zhou QM, Shao WD, Xu B, Xiao HP, Zhang XA.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Jun 30;41(3):373-378. doi: 10.3881/j.issn.1000-503X.10881. Chinese.


Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.

Kiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z.

Geroscience. 2019 May 29. doi: 10.1007/s11357-019-00074-2. [Epub ahead of print]


Preexisting chronic conditions for fatal outcome among SFTS patients: An observational Cohort Study.

Zhang SF, Yang ZD, Huang ML, Wang ZB, Hu YY, Miao D, Dai K, Du J, Cui N, Yuan C, Li H, Li XK, Zhang XA, Zhang PH, Mi XM, Lu QB, Liu W.

PLoS Negl Trop Dis. 2019 May 28;13(5):e0007434. doi: 10.1371/journal.pntd.0007434. eCollection 2019 May.


Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery.

Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Köhler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN.

NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2.


Specific miRNA-G Protein-Coupled Receptor Networks Regulate Sox9a/Sox9b Activities to Promote Gonadal Rejuvenation in Zebrafish.

Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J.

Stem Cells. 2019 Sep;37(9):1189-1199. doi: 10.1002/stem.3040. Epub 2019 Jul 8.


Neuropilin-1 is associated with the prognosis of cervical cancer in Henan Chinese population.

Yang L, Liu L, Zhu YH, Wang BB, Chen YN, Zhang F, Zhang XA, Ren CC.

Onco Targets Ther. 2019 Apr 17;12:2911-2920. doi: 10.2147/OTT.S194349. eCollection 2019.


Recent progress in near-field nanolithography using light interactions with colloidal particles: from nanospheres to three-dimensional nanostructures.

Zhang XA, Chen IT, Chang CH.

Nanotechnology. 2019 Aug 30;30(35):352002. doi: 10.1088/1361-6528/ab2282. Epub 2019 May 17.


Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.

Csiszar A, Balasubramanian P, Tarantini S, Yabluchanskiy A, Zhang XA, Springo Z, Benbrook D, Sonntag WE, Ungvari Z.

Geroscience. 2019 Apr;41(2):209-227. doi: 10.1007/s11357-019-00064-4. Epub 2019 Apr 29. Review.


Rickettsia typhi infection in severe fever with thrombocytopenia patients, China.

Zhang SF, Du J, Mi XM, Lu QB, Bai JY, Cui N, Yang ZD, Wang ZB, Zhang XA, Zhang PH, Li H, Liu W.

Emerg Microbes Infect. 2019;8(1):579-584. doi: 10.1080/22221751.2019.1599696. No abstract available.


Identification and complete genome characterization of human enterovirus 117 from a child with pneumonia in China.

Du J, Zhu T, Zhuang L, Zhang PH, Zhang XA, Lu QB, Liu W.

Arch Virol. 2019 May;164(5):1489-1492. doi: 10.1007/s00705-019-04196-y. Epub 2019 Mar 16.


Dynamic gating of infrared radiation in a textile.

Zhang XA, Yu S, Xu B, Li M, Peng Z, Wang Y, Deng S, Wu X, Wu Z, Ouyang M, Wang Y.

Science. 2019 Feb 8;363(6427):619-623. doi: 10.1126/science.aau1217.


CP‑31398 attenuates endometrial cancer cell invasion, metastasis and resistance to apoptosis by downregulating MDM2 expression.

Liu L, Yang L, Chang H, Chen YN, Zhang F, Feng S, Peng J, Ren CC, Zhang XA.

Int J Oncol. 2019 Mar;54(3):942-954. doi: 10.3892/ijo.2019.4681. Epub 2019 Jan 9.


HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells.

Zhang F, Ren CC, Liu L, Chen YN, Yang L, Zhang XA.

Cancer Cell Int. 2018 Dec 12;18:204. doi: 10.1186/s12935-018-0680-2. eCollection 2018.


Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.

Köhler S, Carmody L, Vasilevsky N, Jacobsen JOB, Danis D, Gourdine JP, Gargano M, Harris NL, Matentzoglu N, McMurry JA, Osumi-Sutherland D, Cipriani V, Balhoff JP, Conlin T, Blau H, Baynam G, Palmer R, Gratian D, Dawkins H, Segal M, Jansen AC, Muaz A, Chang WH, Bergerson J, Laulederkind SJF, Yüksel Z, Beltran S, Freeman AF, Sergouniotis PI, Durkin D, Storm AL, Hanauer M, Brudno M, Bello SM, Sincan M, Rageth K, Wheeler MT, Oegema R, Lourghi H, Della Rocca MG, Thompson R, Castellanos F, Priest J, Cunningham-Rundles C, Hegde A, Lovering RC, Hajek C, Olry A, Notarangelo L, Similuk M, Zhang XA, Gómez-Andrés D, Lochmüller H, Dollfus H, Rosenzweig S, Marwaha S, Rath A, Sullivan K, Smith C, Milner JD, Leroux D, Boerkoel CF, Klion A, Carter MC, Groza T, Smedley D, Haendel MA, Mungall C, Robinson PN.

Nucleic Acids Res. 2019 Jan 8;47(D1):D1018-D1027. doi: 10.1093/nar/gky1105.


Propofol-sparing effect of different concentrations of dexmedetomidine : Comparison of gender differences.

Xiong M, Zheng Z-, Hu ZR, He J, Madubuko U, Grech D, Zhang XA, Xu B.

Anaesthesist. 2019 Jan;68(1):15-21. doi: 10.1007/s00101-018-0506-6. Epub 2018 Nov 7.


Controllable 2H-to-1T' phase transition in few-layer MoTe2.

Tan Y, Luo F, Zhu M, Xu X, Ye Y, Li B, Wang G, Luo W, Zheng X, Wu N, Yu Y, Qin S, Zhang XA.

Nanoscale. 2018 Nov 1;10(42):19964-19971. doi: 10.1039/c8nr06115g.


A background-subtraction strategy leads to ratiometric sensing of oxygen without recalibration.

Zhang Y, Ding L, Zhang W, Zhang XA, Lian Y, Wang XD.

Analyst. 2018 Oct 22;143(21):5120-5126. doi: 10.1039/c8an00967h.


Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome.

Li XK, Lu QB, Chen WW, Xu W, Liu R, Zhang SF, Du J, Li H, Yao K, Zhai D, Zhang PH, Xing B, Cui N, Yang ZD, Yuan C, Zhang XA, Xu Z, Cao WC, Hu Z, Liu W.

Sci Transl Med. 2018 Sep 19;10(459). pii: eaat4162. doi: 10.1126/scitranslmed.aat4162.


Correction to: Tetraspanin-enriched microdomains regulate digitation junctions.

Huang C, Fu C, Wren JD, Wang X, Zhang F, Zhang YH, Connell SA, Chen T, Zhang XA.

Cell Mol Life Sci. 2018 Nov;75(21):4077. doi: 10.1007/s00018-018-2909-6.


CP-31398 inhibits the progression of cervical cancer through reversing the epithelial mesenchymal transition via the downregulation of PAX2s.

Liu L, Yu TT, Ren CC, Yang L, Cui SH, Zhang XA.

J Cell Physiol. 2019 Mar;234(3):2929-2942. doi: 10.1002/jcp.27109. Epub 2018 Aug 21.


Determination of multipool contributions to endogenous amide proton transfer effects in global ischemia with high spectral resolution in vivo chemical exchange saturation transfer MRI.

Zhou IY, Lu D, Ji Y, Wu L, Wang E, Cheung JS, Zhang XA, Sun PZ.

Magn Reson Med. 2019 Jan;81(1):645-652. doi: 10.1002/mrm.27385. Epub 2018 Jul 29.


Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population.

Xing B, Li XK, Zhang SF, Lu QB, Du J, Zhang PH, Yang ZD, Cui N, Guo CT, Cao WC, Zhang XA, Liu W.

PLoS Negl Trop Dis. 2018 Jun 25;12(6):e0006547. doi: 10.1371/journal.pntd.0006547. eCollection 2018 Jun.


Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.

Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):853-863. doi: 10.1093/gerona/glx177.


Manganese-porphyrin-enhanced MRI for the detection of cancer cells: A quantitative in vitro investigation with multiple clinical subtypes of breast cancer.

Alhamami M, Cheng W, Lyu Y, Allen C, Zhang XA, Cheng HL.

PLoS One. 2018 May 24;13(5):e0196998. doi: 10.1371/journal.pone.0196998. eCollection 2018. Erratum in: PLoS One. 2018 Nov 12;13(11):e0206720.


RNAi‑mediated downregulation of asparaginase‑like protein 1 inhibits growth and promotes apoptosis of human cervical cancer line SiHa.

Lv XF, Hong HQ, Liu L, Cui SH, Ren CC, Li HY, Zhang XA, Zhang LD, Wei TX, Liu JJ, Xing WY, Fu H, Yan SJ.

Mol Med Rep. 2018 Jul;18(1):931-937. doi: 10.3892/mmr.2018.9018. Epub 2018 May 14.


Transmission of Severe Fever with Thrombocytopenia Syndrome Virus by Haemaphysalis longicornis Ticks, China.

Zhuang L, Sun Y, Cui XM, Tang F, Hu JG, Wang LY, Cui N, Yang ZD, Huang DD, Zhang XA, Liu W, Cao WC.

Emerg Infect Dis. 2018 May;24(5). doi: 10.3201/eid2405.151435.


Tetraspanin-enriched microdomains regulate digitation junctions.

Huang C, Fu C, Wren JD, Wang X, Zhang F, Zhang YH, Connel SA, Chen T, Zhang XA.

Cell Mol Life Sci. 2018 Sep;75(18):3423-3439. doi: 10.1007/s00018-018-2803-2. Epub 2018 Mar 27. Erratum in: Cell Mol Life Sci. 2018 Nov;75(21):4077.


MiR-124 aggravates failing hearts by suppressing CD151-facilitated angiogenesis in heart.

Zhao Y, Yan M, Chen C, Gong W, Yin Z, Li H, Fan J, Zhang XA, Wang DW, Zuo H.

Oncotarget. 2018 Jan 12;9(18):14382-14396. doi: 10.18632/oncotarget.24205. eCollection 2018 Mar 6.


Synthesis of highly stable cyanine-dye-doped silica nanoparticle for biological applications.

Lian Y, Ding LJ, Zhang W, Zhang XA, Zhang YL, Lin ZZ, Wang XD.

Methods Appl Fluoresc. 2018 Apr 27;6(3):034002. doi: 10.1088/2050-6120/aab930.


High Throughput NPY-Venus and Serotonin Secretion Assays for Regulated Exocytosis in Neuroendocrine Cells.

Zhang XA, Martin TFJ.

Bio Protoc. 2018 Jan 5;8(1). pii: e2680. doi: 10.21769/BioProtoc.2680.


Photoactuated Pens for Molecular Printing.

Huang Z, Li L, Zhang XA, Alsharif N, Wu X, Peng Z, Cheng X, Wang P, Brown KA, Wang Y.

Adv Mater. 2018 Feb;30(8). doi: 10.1002/adma.201705303. Epub 2017 Dec 22.


Twin photonic nanojets generated from coherent illumination of microscale sphere and cylinder.

Poteet A, Zhang XA, Nagai H, Chang CH.

Nanotechnology. 2018 Feb 16;29(7):075204. doi: 10.1088/1361-6528/aaa35d.


Phase-Controlled Growth of One-Dimensional Mo6Te6 Nanowires and Two-Dimensional MoTe2 Ultrathin Films Heterostructures.

Yu Y, Wang G, Tan Y, Wu N, Zhang XA, Qin S.

Nano Lett. 2018 Feb 14;18(2):675-681. doi: 10.1021/acs.nanolett.7b03058. Epub 2017 Dec 26.


Effects of shRNA-mediated silencing of PSMA7 on cell proliferation and vascular endothelial growth factor expression via the ubiquitin-proteasome pathway in cervical cancer.

Ren CC, Yang L, Liu L, Chen YN, Cheng GM, Zhang XA, Liu H.

J Cell Physiol. 2019 May;234(5):5851-5862. doi: 10.1002/jcp.26408. Epub 2018 Dec 11.


Nanostructured antireflective in-plane solar harvester.

Tippens J, Bagal A, Zhang XA, Chang CH.

Opt Express. 2017 Aug 7;25(16):A840-A850. doi: 10.1364/OE.25.00A840.


Enhanced total internal reflection using low-index nanolattice materials.

Zhang XA, Chen YA, Bagal A, Chang CH.

Opt Lett. 2017 Oct 15;42(20):4123-4126. doi: 10.1364/OL.42.004123.


SHH gene silencing suppresses epithelial-mesenchymal transition, proliferation, invasion, and migration of cervical cancer cells by repressing the hedgehog signaling pathway.

Zhang F, Ren CC, Liu L, Chen YN, Yang L, Zhang XA, Wang XM, Yu FJ.

J Cell Biochem. 2018 May;119(5):3829-3842. doi: 10.1002/jcb.26414. Epub 2017 Oct 27.


Association between peripheral γδ T cell subsets and disease progression of severe fever with thrombocytopenia syndrome virus infection.

Xu W, Li XK, Lu QB, Yang ZD, Du J, Xing B, Cui N, Zhang XA, Zhang SF, Yang XX, Liu W, Chen WW.

Pathog Dis. 2017 Sep 29;75(7). doi: 10.1093/femspd/ftx086.


Large-Area Nanolattice Film with Enhanced Modulus, Hardness, and Energy Dissipation.

Bagal A, Zhang XA, Shahrin R, Dandley EC, Zhao J, Poblete FR, Oldham CJ, Zhu Y, Parsons GN, Bobko C, Chang CH.

Sci Rep. 2017 Aug 22;7(1):9145. doi: 10.1038/s41598-017-09521-6.


Endothelial activation and dysfunction in severe fever with thrombocytopenia syndrome.

Li XK, Yang ZD, Du J, Xing B, Cui N, Zhang PH, Li H, Zhang XA, Lu QB, Liu W.

PLoS Negl Trop Dis. 2017 Aug 14;11(8):e0005746. doi: 10.1371/journal.pntd.0005746. eCollection 2017 Aug.


Employee conscientiousness, agreeableness, and supervisor justice rule compliance: A three-study investigation.

Huang JL, Cropanzano R, Li A, Shao P, Zhang XA, Li Y.

J Appl Psychol. 2017 Nov;102(11):1564-1589. doi: 10.1037/apl0000248. Epub 2017 Jul 27.


[Association between IL-6 C-572G and susceptibility to spontaneous preterm birth].

Yang X, Peng W, Zhu LN, Zhang XA, Wang Y.

Zhongguo Dang Dai Er Ke Za Zhi. 2017 Jul;19(7):806-811. Chinese.


Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China.

Zhu T, Lu QB, Zhang SY, Wo Y, Zhuang L, Zhang PH, Zhang XA, Wei W, Liu W.

Future Microbiol. 2017 May;12:481-489. doi: 10.2217/fmb-2016-0144. Epub 2017 May 8.


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