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NLRP3 inflammasome and lipid metabolism analysis based on UPLC-Q-TOF-MS in gouty nephropathy.

Zhang YZ, Sui XL, Xu YP, Gu FJ, Zhang AS, Chen JH.

Int J Mol Med. 2019 Jul;44(1):172-184. doi: 10.3892/ijmm.2019.4176. Epub 2019 Apr 30.


The catalytic, stem, and transmembrane portions of matriptase-2 are required for suppressing the expression of the iron-regulatory hormone hepcidin.

Mao P, Wortham AM, Enns CA, Zhang AS.

J Biol Chem. 2019 Feb 8;294(6):2060-2073. doi: 10.1074/jbc.RA118.006468. Epub 2018 Dec 17.


A long sought after "receptor" for ERFE?

Zhang AS, Enns CA.

Blood. 2018 Oct 4;132(14):1463-1464. doi: 10.1182/blood-2018-08-869586. No abstract available.


The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14.

Zhao N, Zhang AS, Wortham AM, Jue S, Knutson MD, Enns CA.

Nutrients. 2017 Dec 8;9(12). pii: E1335. doi: 10.3390/nu9121335.


Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway.

Wahedi M, Wortham AM, Kleven MD, Zhao N, Jue S, Enns CA, Zhang AS.

J Biol Chem. 2017 Nov 3;292(44):18354-18371. doi: 10.1074/jbc.M117.801795. Epub 2017 Sep 18.


Acute radiology rarely confirms sinus disease in suspected recurrent acute rhinosinusitis.

Barham HP, Zhang AS, Christensen JM, Sacks R, Harvey RJ.

Int Forum Allergy Rhinol. 2017 Jul;7(7):726-733. doi: 10.1002/alr.21925. Epub 2017 May 11.


Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration.

Xu YP, Sui XL, Zhang AS, Ye L, Gu FJ, Chen JH.

Oncotarget. 2017 May 23;8(21):34992-35008. doi: 10.18632/oncotarget.16533.


Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.

Zhang AS, Ostrom QT, Kruchko C, Rogers L, Peereboom DM, Barnholtz-Sloan JS.

Neuro Oncol. 2017 May 1;19(5):726-735. doi: 10.1093/neuonc/now252.


Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.

Zhao N, Maxson JE, Zhang RH, Wahedi M, Enns CA, Zhang AS.

J Biol Chem. 2016 Jun 3;291(23):12322-35. doi: 10.1074/jbc.M116.721191. Epub 2016 Apr 12.


Bone Morphogenetic Protein-6 Mutations Take Their Place in Iron Overload Diseases.

Kleven MD, Enns CA, Zhang AS.

Gastroenterology. 2016 Mar;150(3):556-9. doi: 10.1053/j.gastro.2016.01.016. Epub 2016 Jan 25. No abstract available.


Melatonin attenuates inflammation of acute pulpitis subjected to dental pulp injury.

Li JG, Lin JJ, Wang ZL, Cai WK, Wang PN, Jia Q, Zhang AS, Wu GY, Zhu GX, Ni LX.

Am J Transl Res. 2015 Jan 15;7(1):66-78. eCollection 2015.


Low intracellular iron increases the stability of matriptase-2.

Zhao N, Nizzi CP, Anderson SA, Wang J, Ueno A, Tsukamoto H, Eisenstein RS, Enns CA, Zhang AS.

J Biol Chem. 2015 Feb 13;290(7):4432-46. doi: 10.1074/jbc.M114.611913. Epub 2014 Dec 30.


[Effects of different host plants on the cold-resistant substances in overwintering larvae of Carposina sasakii Matsumura (Lepidoptera: Carposinidae)].

Wang P, Yu Y, Xu YY, Li LL, Zhang AS, Men XY, Zhang SC, Zhou XH.

Ying Yong Sheng Tai Xue Bao. 2014 May;25(5):1513-7. Chinese.


An iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14.

Zhao N, Zhang AS, Worthen C, Knutson MD, Enns CA.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9175-80. doi: 10.1073/pnas.1405355111. Epub 2014 Jun 9.


First Report of Dimethachlon Resistance in Field Isolates of Sclerotinia sclerotiorum on Oilseed Rape in Shaanxi Province of Northwestern China.

Zhou F, Zhu FX, Zhang XL, Zhang AS.

Plant Dis. 2014 Apr;98(4):568. doi: 10.1094/PDIS-07-13-0730-PDN.


Lymphatic absorption, metabolism, and excretion of a therapeutic peptide in dogs and rats.

Zou Y, Bateman TJ, Adreani C, Shen X, Cunningham PK, Wang B, Trinh T, Christine A, Hong X, Nunes CN, Johnson CV, Zhang AS, Staskiewicz SJ, Braun M, Kumar S, Reddy VB.

Drug Metab Dispos. 2013 Dec;41(12):2206-14. doi: 10.1124/dmd.113.051524. Epub 2013 Oct 2.


Chemical characteristics of normal, woolly apple aphid-damaged, and mechanically damaged twigs of six apple cultivars, measured in autumn wood.

Zhou HX, Wang XC, Yu Y, Tan XM, Cheng ZQ, Zhang AS, Men XY, Li-Li L.

J Econ Entomol. 2013 Apr;106(2):1011-7.


Iron regulation by hepcidin.

Zhao N, Zhang AS, Enns CA.

J Clin Invest. 2013 Jun;123(6):2337-43. doi: 10.1172/JCI67225. Epub 2013 Jun 3.


Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway.

Enns CA, Ahmed R, Wang J, Ueno A, Worthen C, Tsukamoto H, Zhang AS.

PLoS One. 2013;8(4):e60534. doi: 10.1371/journal.pone.0060534. Epub 2013 Apr 2.


[Resistance mechanisms and cross-resistance of phoxim-resistant Frankliniella occidentalis Pergande population].

Wang SY, Zhou XH, Zhang AS, Li LL, Men XY, Zhang SC, Liu YJ, Yu Y.

Ying Yong Sheng Tai Xue Bao. 2012 Jul;23(7):1933-9. Chinese.


Tuning of the ocular vestibular evoked myogenic potential (oVEMP) to air- and bone-conducted sound stimulation in superior canal dehiscence.

Zhang AS, Govender S, Colebatch JG.

Exp Brain Res. 2012 Nov;223(1):51-64. doi: 10.1007/s00221-012-3240-3. Epub 2012 Sep 2.


Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage.

Enns CA, Ahmed R, Zhang AS.

J Biol Chem. 2012 Oct 12;287(42):35104-17. doi: 10.1074/jbc.M112.363937. Epub 2012 Aug 14.


Tuning of the ocular vestibular evoked myogenic potential to bone-conducted sound stimulation.

Zhang AS, Govender S, Colebatch JG.

J Appl Physiol (1985). 2012 Apr;112(8):1279-90. doi: 10.1152/japplphysiol.01024.2011. Epub 2012 Feb 2.


Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis.

Zhang AS.

Adv Nutr. 2010 Nov;1(1):38-45. doi: 10.3945/an.110.1009. Epub 2010 Nov 16.


Superior canal dehiscence causes abnormal vestibular bone-conducted tuning.

Zhang AS, Govender S, Colebatch JG.

Neurology. 2011 Aug 30;77(9):911-3. doi: 10.1212/WNL.0b013e31822c6263. Epub 2011 Aug 17. No abstract available.


Tuning of the ocular vestibular evoked myogenic potential (oVEMP) to AC sound shows two separate peaks.

Zhang AS, Govender S, Colebatch JG.

Exp Brain Res. 2011 Aug;213(1):111-6. doi: 10.1007/s00221-011-2783-z. Epub 2011 Jun 30.


Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein.

Zhang AS, Anderson SA, Wang J, Yang F, DeMaster K, Ahmed R, Nizzi CP, Eisenstein RS, Tsukamoto H, Enns CA.

Blood. 2011 Feb 3;117(5):1687-99. doi: 10.1182/blood-2010-06-287292. Epub 2010 Nov 29.


Matriptase-2- and proprotein convertase-cleaved forms of hemojuvelin have different roles in the down-regulation of hepcidin expression.

Maxson JE, Chen J, Enns CA, Zhang AS.

J Biol Chem. 2010 Dec 10;285(50):39021-8. doi: 10.1074/jbc.M110.183160. Epub 2010 Oct 11.


Metabolism and excretion of [14C]taranabant, a cannabinoid-1 inverse agonist, in humans.

Karanam B, Addy C, Bateman T, Reddy VB, Li S, Dean D, Li H, Jones A, Schenk D, Zhang AS, Braun M, Freeman A, Flach S, Stoch A, Chodakewitz J, Wagner JA, Kumar S.

Xenobiotica. 2010 Oct;40(10):691-700. doi: 10.3109/00498254.2010.509820.


In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys.

Reddy VB, Doss GA, Karanam BV, Samuel K, Lanza TJ Jr, Lin LS, Yu NX, Zhang AS, Raab CE, Stearns RA, Kumar S.

Xenobiotica. 2010 Sep;40(9):650-62. doi: 10.3109/00498254.2010.501117.


The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.

Zhang AS, Gao J, Koeberl DD, Enns CA.

J Biol Chem. 2010 May 28;285(22):16416-23. doi: 10.1074/jbc.M110.109488. Epub 2010 Apr 2.


Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys.

Tan EY, Hartmann G, Chen Q, Pereira A, Bradley S, Doss G, Zhang AS, Ho JZ, Braun MP, Dean DC, Tang W, Kumar S.

Drug Metab Dispos. 2010 Mar;38(3):459-73. doi: 10.1124/dmd.109.028696. Epub 2009 Dec 16.


Molecular mechanisms of normal iron homeostasis.

Zhang AS, Enns CA.

Hematology Am Soc Hematol Educ Program. 2009:207-14. doi: 10.1182/asheducation-2009.1.207. Review.


Stoichiometries of transferrin receptors 1 and 2 in human liver.

Chloupkov√° M, Zhang AS, Enns CA.

Blood Cells Mol Dis. 2010 Jan 15;44(1):28-33. doi: 10.1016/j.bcmd.2009.09.004. Epub 2009 Oct 12.


Hemojuvelin-neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression.

Zhang AS, Yang F, Wang J, Tsukamoto H, Enns CA.

J Biol Chem. 2009 Aug 21;284(34):22580-9. doi: 10.1074/jbc.M109.027318. Epub 2009 Jun 29.


Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.

Gao J, Chen J, Kramer M, Tsukamoto H, Zhang AS, Enns CA.

Cell Metab. 2009 Mar;9(3):217-27. doi: 10.1016/j.cmet.2009.01.010.


Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells.

Maxson JE, Enns CA, Zhang AS.

Blood. 2009 Feb 19;113(8):1786-93. doi: 10.1182/blood-2008-08-174565. Epub 2008 Nov 24.


Iron homeostasis: recently identified proteins provide insight into novel control mechanisms.

Zhang AS, Enns CA.

J Biol Chem. 2009 Jan 9;284(2):711-5. doi: 10.1074/jbc.R800017200. Epub 2008 Aug 29. Review.


Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms.

Zhang AS, Canonne-Hergaux F, Gruenheid S, Gros P, Ponka P.

Exp Hematol. 2008 Oct;36(10):1227-35. doi: 10.1016/j.exphem.2008.04.014. Epub 2008 Aug 22.


Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis.

Xiong S, She H, Zhang AS, Wang J, Mkrtchyan H, Dynnyk A, Gordeuk VR, French SW, Enns CA, Tsukamoto H.

Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G512-21. doi: 10.1152/ajpgi.90327.2008. Epub 2008 Jul 3.


Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane.

Zhang AS, Yang F, Meyer K, Hernandez C, Chapman-Arvedson T, Bjorkman PJ, Enns CA.

J Biol Chem. 2008 Jun 20;283(25):17494-502. doi: 10.1074/jbc.M710527200. Epub 2008 Apr 29.


Direct interorganellar transfer of iron from endosome to mitochondrion.

Sheftel AD, Zhang AS, Brown C, Shirihai OS, Ponka P.

Blood. 2007 Jul 1;110(1):125-32. Epub 2007 Mar 21.


Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin.

Zhang AS, Anderson SA, Meyers KR, Hernandez C, Eisenstein RS, Enns CA.

J Biol Chem. 2007 Apr 27;282(17):12547-56. Epub 2007 Mar 1.


The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling.

Zhang AS, Sheftel AD, Ponka P.

Exp Hematol. 2006 May;34(5):593-8.


Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells.

Zhang AS, West AP Jr, Wyman AE, Bjorkman PJ, Enns CA.

J Biol Chem. 2005 Oct 7;280(40):33885-94. Epub 2005 Aug 15.


Wind-dispersed seed deposition patterns and seedling recruitment of Artemisia halodendron in a moving sandy land.

Li FR, Wang T, Zhang AS, Zhao LY, Kang LF, Chen W.

Ann Bot. 2005 Jul;96(1):69-80. Epub 2005 Apr 27.


The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells.

Carlson H, Zhang AS, Fleming WH, Enns CA.

Blood. 2005 Mar 15;105(6):2564-70. Epub 2004 Nov 4.


Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria.

Zhang AS, Sheftel AD, Ponka P.

Blood. 2005 Jan 1;105(1):368-75. Epub 2004 Aug 26.


Gene expression differences of regenerating rat liver in a short interval successive partial hepatectomy.

Xu CS, Zhang AS, Han HP, Yuan JY, Chang CF, Li WQ, Yang KJ, Zhao LF, Li YC, Zhang HY, Rahman S, Zhang JB.

World J Gastroenterol. 2004 Sep 15;10(18):2680-9.

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