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Items: 1 to 50 of 482

1.

Automatic Corneal Ulcer Segmentation Combining Gaussian Mixture Modeling and Otsu Method.

Liu Z, Shi Y, Zhan P, Zhang Y, Gong Y, Tang X.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:6298-6301. doi: 10.1109/EMBC.2019.8857522.

PMID:
31947282
2.

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidines Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.

Kang D, Ruiz FX, Feng D, Pilch A, Zhao T, Wei F, Wang Z, Sun Y, Fang Z, De Clercq E, Pannecouque C, Arnold E, Zhan P, Liu X.

J Med Chem. 2020 Jan 14. doi: 10.1021/acs.jmedchem.9b01769. [Epub ahead of print]

PMID:
31935327
3.

The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation.

Shu Z, Miao X, Tang T, Zhan P, Zeng L, Jiang Y.

Int J Mol Med. 2020 Jan 9. doi: 10.3892/ijmm.2020.4460. [Epub ahead of print]

PMID:
31922219
4.

DNA Origami Catenanes Templated by Gold Nanoparticles.

Peil A, Zhan P, Liu N.

Small. 2020 Jan 9:e1905987. doi: 10.1002/smll.201905987. [Epub ahead of print]

PMID:
31917513
5.

Chromosome 1q21 translocation and spermatogenesis failure: Two case reports and review of the literature.

Li R, Wang X, Feng S, Yang X, Zhang Q, Zhan P.

Medicine (Baltimore). 2019 Dec;98(52):e18588. doi: 10.1097/MD.0000000000018588. Review.

6.

Geranylgeranyl diphosphate synthase 1 knockout ameliorates ventilator-induced lung injury via regulation of TLR2/4-AP-1 signaling.

Wan B, Xu WJ, Chen MZ, Sun SS, Jin JJ, Lv YL, Zhan P, Zhu SH, Wang XX, Lv TF, Song Y.

Free Radic Biol Med. 2020 Feb 1;147:159-166. doi: 10.1016/j.freeradbiomed.2019.12.024. Epub 2019 Dec 24.

PMID:
31874250
7.

A Sequential Higher Order Latent Structural Model for Hierarchical Attributes in Cognitive Diagnostic Assessments.

Zhan P, Ma W, Jiao H, Ding S.

Appl Psychol Meas. 2020 Jan;44(1):65-83. doi: 10.1177/0146621619832935. Epub 2019 Mar 4.

PMID:
31853159
8.

Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity.

Ju H, Xiu S, Ding X, Shang M, Jia R, Huang B, Zhan P, Liu X.

Eur J Med Chem. 2020 Feb 1;187:111940. doi: 10.1016/j.ejmech.2019.111940. Epub 2019 Dec 3.

PMID:
31835169
9.

DNA-assembled nanoarchitectures with multiple components in regulated and coordinated motion.

Zhan P, Urban MJ, Both S, Duan X, Kuzyk A, Weiss T, Liu N.

Sci Adv. 2019 Nov 29;5(11):eaax6023. doi: 10.1126/sciadv.aax6023. eCollection 2019 Nov.

10.

Physical connectivity simulations reveal dynamic linkages between coral reefs in the southern Red Sea and the Indian Ocean.

Wang Y, Raitsos DE, Krokos G, Gittings JA, Zhan P, Hoteit I.

Sci Rep. 2019 Nov 12;9(1):16598. doi: 10.1038/s41598-019-53126-0.

11.

Complete genome sequence of Echinicola rosea JL3085, a xylan and pectin decomposer.

Zhan P, Ye J, Lin X, Zhang F, Lin D, Zhang Y, Tang K.

Mar Genomics. 2019 Oct 30:100722. doi: 10.1016/j.margen.2019.100722. [Epub ahead of print]

PMID:
31677976
12.

WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression.

Zhang Q, Fan H, Liu H, Jin J, Zhu S, Zhou L, Liu H, Zhang F, Zhan P, Lv T, Song Y.

Oncogene. 2019 Oct 30. doi: 10.1038/s41388-019-1071-4. [Epub ahead of print]

PMID:
31666682
13.

Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2.

Lv J, Zhang S, Wu H, Lu J, Lu Y, Wang F, Zhao W, Zhan P, Lu J, Fang Q, Xie C, Yin Z.

Cancer Lett. 2020 Jan 28;469:22-34. doi: 10.1016/j.canlet.2019.10.025. Epub 2019 Oct 18.

PMID:
31634528
14.

Giant paravertebral schwannoma near the lumbar nerve roots with bone destruction: A case report.

Chen H, Xu Q, Zhan P, Liu Y, Dai M, Zhang B.

Medicine (Baltimore). 2019 Oct;98(42):e17341. doi: 10.1097/MD.0000000000017341.

15.

Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2016-2019).

Dong Y, Zhao T, Ai W, Zalloum WA, Kang D, Wu T, Liu X, Zhan P.

Expert Opin Ther Pat. 2019 Nov;29(11):871-879. doi: 10.1080/13543776.2019.1676727. Epub 2019 Oct 14. Review.

PMID:
31593642
16.

The clinicopathological and prognostic significance of PD-L1 expression assessed by immunohistochemistry in lung cancer: a meta-analysis of 50 studies with 11,383 patients.

Li H, Xu Y, Wan B, Song Y, Zhan P, Hu Y, Zhang Q, Zhang F, Liu H, Li T, Sugimura H, Cappuzzo F, Lin D, Lv T; written on behalf of AME Lung Cancer Collaborative Group.

Transl Lung Cancer Res. 2019 Aug;8(4):429-449. doi: 10.21037/tlcr.2019.08.04.

17.

The association of PD-L1 expression with the efficacy of anti-PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis of randomized controlled trials.

Xu Y, Wan B, Chen X, Zhan P, Zhao Y, Zhang T, Liu H, Afzal MZ, Dermime S, Hochwald SN, Hofman P, Borghaei H, Lin D, Lv T, Song Y; written on behalf of AME Lung Cancer Collaborative Group.

Transl Lung Cancer Res. 2019 Aug;8(4):413-428. doi: 10.21037/tlcr.2019.08.09.

18.

Joint Modeling of Compensatory Multidimensional Item Responses and Response Times.

Man K, Harring JR, Jiao H, Zhan P.

Appl Psychol Meas. 2019 Nov;43(8):639-654. doi: 10.1177/0146621618824853. Epub 2019 Feb 22.

PMID:
31551641
19.

Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries.

Jing L, Wu G, Hao X, Olotu FA, Kang D, Chen CH, Lee KH, Soliman MES, Liu X, Song Y, Zhan P.

Eur J Med Chem. 2019 Dec 1;183:111696. doi: 10.1016/j.ejmech.2019.111696. Epub 2019 Sep 14.

PMID:
31541869
20.

A New Diagnostic Medium for Cervical Spondylotic Myelopathy: Dynamic Somatosensory Evoked Potentials.

Qi Q, Huang S, Ling Z, Chen Y, Hu H, Zhan P, Zhang B, Zou X, Peng X.

World Neurosurg. 2020 Jan;133:e225-e232. doi: 10.1016/j.wneu.2019.08.205. Epub 2019 Sep 4.

PMID:
31493599
21.

DNA-Assembled Multilayer Sliding Nanosystems.

Zhan P, Both S, Weiss T, Liu N.

Nano Lett. 2019 Sep 11;19(9):6385-6390. doi: 10.1021/acs.nanolett.9b02565. Epub 2019 Aug 28.

22.

Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing.

Zhao T, Meng Q, Kang D, Ji J, De Clercq E, Pannecouque C, Liu X, Zhan P.

Eur J Med Chem. 2019 Nov 15;182:111619. doi: 10.1016/j.ejmech.2019.111619. Epub 2019 Aug 14.

PMID:
31434039
23.

Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment.

Zhang T, Wan B, Zhao Y, Li C, Liu H, Lv T, Zhan P, Song Y.

Transl Lung Cancer Res. 2019 Jun;8(3):302-316. doi: 10.21037/tlcr.2019.04.12. Review.

24.

Prognostic role of pretreatment neutrophil-to-lymphocyte ratio in non-small cell lung cancer patients treated with systemic therapy: a meta-analysis.

Wang Z, Zhan P, Lv Y, Shen K, Wei Y, Liu H, Song Y.

Transl Lung Cancer Res. 2019 Jun;8(3):214-226. doi: 10.21037/tlcr.2019.06.10.

25.

Differentiated human adipose-derived stromal cells exhibit the phenotypic and functional characteristics of mature Schwann cells through a modified approach.

Kang Y, Liu Y, Liu Z, Ren S, Xiong H, Chen J, Duscher D, Machens HG, Liu W, Guo G, Zhan P, Chen H, Chen Z.

Cytotherapy. 2019 Sep;21(9):987-1003. doi: 10.1016/j.jcyt.2019.04.061. Epub 2019 Jul 25.

PMID:
31351800
26.

Zebrafish Xenograft Model of Human Lung Cancer for Evaluating Osimertinib Resistance.

Li XY, Huang LT, Wu JQ, He MF, Zhu SH, Zhan P, Lv TF, Song Y.

Biomed Res Int. 2019 Jun 27;2019:3129748. doi: 10.1155/2019/3129748. eCollection 2019.

27.

Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H,3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase.

Gao P, Cheng X, Sun L, Song S, Álvarez M, Luczkowiak J, Pannecouque C, De Clercq E, Menéndez-Arias L, Zhan P, Liu X.

Bioorg Med Chem. 2019 Sep 1;27(17):3836-3845. doi: 10.1016/j.bmc.2019.07.011. Epub 2019 Jul 6.

PMID:
31324562
28.

Visualization of Higher-Order Topological Insulating Phases in Two-Dimensional Dielectric Photonic Crystals.

Xie BY, Su GX, Wang HF, Su H, Shen XP, Zhan P, Lu MH, Wang ZL, Chen YF.

Phys Rev Lett. 2019 Jun 14;122(23):233903. doi: 10.1103/PhysRevLett.122.233903.

PMID:
31298912
29.

GSDMD is required for effector CD8+ T cell responses to lung cancer cells.

Xi G, Gao J, Wan B, Zhan P, Xu W, Lv T, Song Y.

Int Immunopharmacol. 2019 Sep;74:105713. doi: 10.1016/j.intimp.2019.105713. Epub 2019 Jul 2.

PMID:
31276977
30.

Design, synthesis and biological evaluation of "Multi-Site"-binding influenza virus neuraminidase inhibitors.

Jia R, Zhang J, Ai W, Ding X, Desta S, Sun L, Sun Z, Ma X, Li Z, Wang D, Huang B, Zhan P, Liu X.

Eur J Med Chem. 2019 Sep 15;178:64-80. doi: 10.1016/j.ejmech.2019.05.076. Epub 2019 May 30.

PMID:
31176096
31.

Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors.

Hao X, Zuo X, Kang D, Zhang J, Song Y, Liu X, Zhan P.

Expert Opin Drug Discov. 2019 Sep;14(9):915-931. doi: 10.1080/17460441.2019.1626821. Epub 2019 Jun 7.

PMID:
31172842
32.

Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.

Chen J, Ren S, Duscher D, Kang Y, Liu Y, Wang C, Yuan M, Guo G, Xiong H, Zhan P, Wang Y, Machens HG, Chen Z.

J Cell Physiol. 2019 Dec;234(12):23097-23110. doi: 10.1002/jcp.28873. Epub 2019 May 23.

PMID:
31124125
33.

LAPTM4B facilitates tumor growth and induces autophagy in hepatocellular carcinoma.

Wang F, Wu H, Zhang S, Lu J, Lu Y, Zhan P, Fang Q, Wang F, Zhang X, Xie C, Yin Z.

Cancer Manag Res. 2019 Mar 27;11:2485-2497. doi: 10.2147/CMAR.S201092. eCollection 2019.

34.

Recent applications of click chemistry in drug discovery.

Jiang X, Hao X, Jing L, Wu G, Kang D, Liu X, Zhan P.

Expert Opin Drug Discov. 2019 Aug;14(8):779-789. doi: 10.1080/17460441.2019.1614910. Epub 2019 May 16.

PMID:
31094231
35.

Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions.

Ren L, Zhan P, Wang Q, Wang C, Liu Y, Yu Z, Zhang S.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):691-698. doi: 10.1016/j.bbrc.2019.05.010. Epub 2019 May 9.

PMID:
31078267
36.
37.

MDA19, a novel CB2 agonist, inhibits hepatocellular carcinoma partly through inactivation of AKT signaling pathway.

Rao M, Chen D, Zhan P, Jiang J.

Biol Direct. 2019 May 3;14(1):9. doi: 10.1186/s13062-019-0241-1.

38.

Overview of Recent Strategic Advances in Medicinal Chemistry.

Wu G, Zhao T, Kang D, Zhang J, Song Y, Namasivayam V, Kongsted J, Pannecouque C, De Clercq E, Poongavanam V, Liu X, Zhan P.

J Med Chem. 2019 Nov 14;62(21):9375-9414. doi: 10.1021/acs.jmedchem.9b00359. Epub 2019 May 28.

PMID:
31050421
39.

Inhibition of CDC25B With WG-391D Impedes the Tumorigenesis of Ovarian Cancer.

Xiao Y, Yu Y, Gao D, Jin W, Jiang P, Li Y, Wang C, Song Y, Zhan P, Gu F, Zhang C, Wang B, Chen Y, Du B, Zhang R.

Front Oncol. 2019 Apr 8;9:236. doi: 10.3389/fonc.2019.00236. eCollection 2019.

40.

Molecular design opportunities presented by solvent-exposed regions of target proteins.

Jiang X, Yu J, Zhou Z, Kongsted J, Song Y, Pannecouque C, De Clercq E, Kang D, Poongavanam V, Liu X, Zhan P.

Med Res Rev. 2019 Nov;39(6):2194-2238. doi: 10.1002/med.21581. Epub 2019 Apr 19. Review.

PMID:
31002405
41.

Resurrecting the Condemned: Identification of N-Benzoxaborole Benzofuran GSK8175 as a Clinical Candidate with Reduced Metabolic Liability.

Zhan P, Kang D, Liu X.

J Med Chem. 2019 Apr 11;62(7):3251-3253. doi: 10.1021/acs.jmedchem.9b00415. Epub 2019 Mar 27.

PMID:
30916967
42.

Discovery of novel anti-influenza agents via contemporary medicinal chemistry strategies (2014-2018 update).

Jia R, Zhang J, Ju H, Kang D, Fang Z, Liu X, Zhan P.

Future Med Chem. 2019 Mar;11(5):375-378. doi: 10.4155/fmc-2018-0397. Epub 2019 Mar 19. Review. No abstract available.

PMID:
30887815
43.

Targeting the hydrophobic channel of NNIBP: discovery of novel 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs with high potency against wild-type and K103N mutant virus.

Zhou Z, Liu T, Wu G, Kang D, Fu Z, Wang Z, De Clercq E, Pannecouque C, Zhan P, Liu X.

Org Biomol Chem. 2019 Mar 20;17(12):3202-3217. doi: 10.1039/c9ob00032a.

PMID:
30839042
44.

Design, Synthesis and Evaluation of Novel Heteroaryldihydropyrimidines Derivatives as Non-nucleoside Hepatitis B Virus Inhibitors by Exploring the Solvent-exposed Region.

Yu J, Guo X, Desta S, Zhang S, Zhang J, Ding X, Liang X, Jia H, Liu X, Zhan P.

Chem Biol Drug Des. 2019 Mar 1. doi: 10.1111/cbdd.13512. [Epub ahead of print]

PMID:
30825248
45.

Early recurrence detected in hepatocellular carcinoma patients after transcatheter arterial chemoembolization treatment with plasma cell-free DNA.

Li Z, Xiao D, Li X, Zhan P, Wang J, Zhang H.

Eur J Gastroenterol Hepatol. 2019 Jul;31(7):885-892. doi: 10.1097/MEG.0000000000001373.

PMID:
30807446
46.

Extensive tinea capitis and corporis in a child caused by Trichophyton verrucosum.

Jiang Y, Zhan P, Al-Hatmi AMS, Shi G, Wei Y, van den Ende AHGG, Meis JF, Lu H, de Hoog GS.

J Mycol Med. 2019 Apr;29(1):62-66. doi: 10.1016/j.mycmed.2019.01.007. Epub 2019 Feb 22.

PMID:
30799183
47.

Bayesian DINA Modeling Incorporating Within-Item Characteristic Dependency.

Zhan P, Jiao H, Liao M, Bian Y.

Appl Psychol Meas. 2019 Mar;43(2):143-158. doi: 10.1177/0146621618781594. Epub 2018 Jun 22.

PMID:
30792561
48.

Synthesis and magnetic studies of pentagonal bipyramidal metal complexes of Fe, Co and Ni.

Deng YF, Yao B, Zhan PZ, Gan D, Zhang YZ, Dunbar KR.

Dalton Trans. 2019 Mar 5;48(10):3243-3248. doi: 10.1039/c8dt05074k.

PMID:
30775732
49.

Designing influenza polymerase acidic endonuclease inhibitors via 'privileged scaffold' re-evolution/refining strategy.

Ju H, Zhan P, Liu X.

Future Med Chem. 2019 Feb 14. doi: 10.4155/fmc-2018-0489. [Epub ahead of print] No abstract available.

PMID:
30763130
50.

Effectiveness and safety of PD-1/PD-L1 or CTLA4 inhibitors combined with chemotherapy as a first-line treatment for lung cancer: A meta-analysis.

Shen K, Cui J, Wei Y, Chen X, Liu G, Gao X, Li W, Lu H, Zhan P, Lv T, Lin D.

J Thorac Dis. 2018 Dec;10(12):6636-6652. doi: 10.21037/jtd.2018.11.72.

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