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Items: 21


Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture.

de Wilde AH, Zevenhoven-Dobbe JC, Beugeling C, Chatterji U, de Jong D, Gallay P, Szuhai K, Posthuma CC, Snijder EJ.

Virology. 2018 Apr;517:148-156. doi: 10.1016/j.virol.2017.11.022. Epub 2017 Dec 15.


Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model.

de Wilde AH, Falzarano D, Zevenhoven-Dobbe JC, Beugeling C, Fett C, Martellaro C, Posthuma CC, Feldmann H, Perlman S, Snijder EJ.

Virus Res. 2017 Jan 15;228:7-13. doi: 10.1016/j.virusres.2016.11.011. Epub 2016 Nov 10.


Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses.

Lehmann KC, Gulyaeva A, Zevenhoven-Dobbe JC, Janssen GM, Ruben M, Overkleeft HS, van Veelen PA, Samborskiy DV, Kravchenko AA, Leontovich AM, Sidorov IA, Snijder EJ, Posthuma CC, Gorbalenya AE.

Nucleic Acids Res. 2015 Sep 30;43(17):8416-34. doi: 10.1093/nar/gkv838. Epub 2015 Aug 24.


Arterivirus nsp12 versus the coronavirus nsp16 2'-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins.

Lehmann KC, Hooghiemstra L, Gulyaeva A, Samborskiy DV, Zevenhoven-Dobbe JC, Snijder EJ, Gorbalenya AE, Posthuma CC.

J Gen Virol. 2015 Sep;96(9):2643-55. doi: 10.1099/vir.0.000209. Epub 2015 Jun 3.


One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities.

Subissi L, Posthuma CC, Collet A, Zevenhoven-Dobbe JC, Gorbalenya AE, Decroly E, Snijder EJ, Canard B, Imbert I.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):E3900-9. doi: 10.1073/pnas.1323705111. Epub 2014 Sep 2.


Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture.

de Wilde AH, Jochmans D, Posthuma CC, Zevenhoven-Dobbe JC, van Nieuwkoop S, Bestebroer TM, van den Hoogen BG, Neyts J, Snijder EJ.

Antimicrob Agents Chemother. 2014 Aug;58(8):4875-84. doi: 10.1128/AAC.03011-14. Epub 2014 May 19.


Mass spectrometry-based comparative sequence analysis for the genetic monitoring of influenza A(H1N1)pdm09 virus.

Gooskens J, Zevenhoven-Dobbe JC, Claas EC, Kroes AC, Posthuma CC.

PLoS One. 2014 Apr 3;9(4):e92970. doi: 10.1371/journal.pone.0092970. eCollection 2014.


Arterivirus minor envelope proteins are a major determinant of viral tropism in cell culture.

Tian D, Wei Z, Zevenhoven-Dobbe JC, Liu R, Tong G, Snijder EJ, Yuan S.

J Virol. 2012 Apr;86(7):3701-12. doi: 10.1128/JVI.06836-11. Epub 2012 Jan 18.


Cyclosporin A inhibits the replication of diverse coronaviruses.

de Wilde AH, Zevenhoven-Dobbe JC, van der Meer Y, Thiel V, Narayanan K, Makino S, Snijder EJ, van Hemert MJ.

J Gen Virol. 2011 Nov;92(Pt 11):2542-8. doi: 10.1099/vir.0.034983-0. Epub 2011 Jul 13.


Structure and genetic analysis of the arterivirus nonstructural protein 7alpha.

Manolaridis I, Gaudin C, Posthuma CC, Zevenhoven-Dobbe JC, Imbert I, Canard B, Kelly G, Tucker PA, Conte MR, Snijder EJ.

J Virol. 2011 Jul;85(14):7449-53. doi: 10.1128/JVI.00255-11. Epub 2011 May 11.


Development and RNA-synthesizing activity of coronavirus replication structures in the absence of protein synthesis.

van den Worm SH, Knoops K, Zevenhoven-Dobbe JC, Beugeling C, van der Meer Y, Mommaas AM, Snijder EJ.

J Virol. 2011 Jun;85(11):5669-73. doi: 10.1128/JVI.00403-11. Epub 2011 Mar 23.


Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production.

Firth AE, Zevenhoven-Dobbe JC, Wills NM, Go YY, Balasuriya UB, Atkins JF, Snijder EJ, Posthuma CC.

J Gen Virol. 2011 May;92(Pt 5):1097-106. doi: 10.1099/vir.0.029264-0. Epub 2011 Feb 9.


Myristoylation of the arterivirus E protein: the fatty acid modification is not essential for membrane association but contributes significantly to virus infectivity.

Thaa B, Kabatek A, Zevenhoven-Dobbe JC, Snijder EJ, Herrmann A, Veit M.

J Gen Virol. 2009 Nov;90(Pt 11):2704-12. doi: 10.1099/vir.0.011957-0. Epub 2009 Aug 5.


Production of monospecific rabbit antisera recognizing nidovirus proteins.

Zevenhoven-Dobbe JC, Wassenaar AL, van der Meer Y, Snijder EJ.

Methods Mol Biol. 2008;454:205-26. doi: 10.1007/978-1-59745-181-9_16.


SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum.

Knoops K, Kikkert M, Worm SH, Zevenhoven-Dobbe JC, van der Meer Y, Koster AJ, Mommaas AM, Snijder EJ.

PLoS Biol. 2008 Sep 16;6(9):e226. doi: 10.1371/journal.pbio.0060226.


Formation of the arterivirus replication/transcription complex: a key role for nonstructural protein 3 in the remodeling of intracellular membranes.

Posthuma CC, Pedersen KW, Lu Z, Joosten RG, Roos N, Zevenhoven-Dobbe JC, Snijder EJ.

J Virol. 2008 May;82(9):4480-91. doi: 10.1128/JVI.02756-07. Epub 2008 Feb 27.


The nsp1alpha and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis.

Kroese MV, Zevenhoven-Dobbe JC, Bos-de Ruijter JN, Peeters BP, Meulenberg JJ, Cornelissen LA, Snijder EJ.

J Gen Virol. 2008 Feb;89(Pt 2):494-9. doi: 10.1099/vir.0.83253-0.


Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease.

Tijms MA, Nedialkova DD, Zevenhoven-Dobbe JC, Gorbalenya AE, Snijder EJ.

J Virol. 2007 Oct;81(19):10496-505. Epub 2007 Jul 11.


Development and characterization of an infectious cDNA clone of the virulent Bucyrus strain of Equine arteritis virus.

Balasuriya UB, Snijder EJ, Heidner HW, Zhang J, Zevenhoven-Dobbe JC, Boone JD, McCollum WH, Timoney PJ, MacLachlan NJ.

J Gen Virol. 2007 Mar;88(Pt 3):918-24.


Site-directed mutagenesis of the Nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle.

Posthuma CC, Nedialkova DD, Zevenhoven-Dobbe JC, Blokhuis JH, Gorbalenya AE, Snijder EJ.

J Virol. 2006 Feb;80(4):1653-61.


Rescue of disabled infectious single-cycle (DISC) equine arteritis virus by using complementing cell lines that express minor structural glycoproteins.

Zevenhoven-Dobbe JC, Greve S, van Tol H, Spaan WJ, Snijder EJ.

J Gen Virol. 2004 Dec;85(Pt 12):3709-14.


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