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Items: 1 to 50 of 961

1.

The recency ratio is related to CSF Amyloid Beta 1-42 levels in MCI-AD.

Bruno D, Gleason CE, Koscik RL, Pomara N, Zetterberg H, Blennow K, Johnson SC.

Int J Geriatr Psychiatry. 2018 Nov 14. doi: 10.1002/gps.5029. [Epub ahead of print]

PMID:
30430632
2.

Plasma Markers of Neurodegeneration Are Raised in Friedreich's Ataxia.

Zeitlberger AM, Thomas-Black G, Garcia-Moreno H, Foiani M, Heslegrave AJ, Zetterberg H, Giunti P.

Front Cell Neurosci. 2018 Oct 30;12:366. doi: 10.3389/fncel.2018.00366. eCollection 2018.

3.

Fluid biomarkers for frontotemporal dementias.

Zetterberg H, van Swieten JC, Boxer AL, Rohrer JD.

Neuropathol Appl Neurobiol. 2018 Nov 13. doi: 10.1111/nan.12530. [Epub ahead of print]

PMID:
30422329
4.

The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population.

Rydberg Sterner T, Ahlner F, Blennow K, Dahlin-Ivanoff S, Falk H, Havstam Johansson L, Hoff M, Holm M, Hörder H, Jacobsson T, Johansson B, Johansson L, Kern J, Kern S, Machado A, Mellqvist Fässberg M, Nilsson J, Ribbe M, Rothenberg E, Rydén L, Sadeghi A, Sacuiu S, Samuelsson J, Sigström R, Skoog J, Thorvaldsson V, Waern M, Westman E, Wetterberg H, Zetterberg H, Zetterberg M, Zettergren A, Östling S, Skoog I.

Eur J Epidemiol. 2018 Nov 13. doi: 10.1007/s10654-018-0459-8. [Epub ahead of print]

PMID:
30421322
5.

Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.

Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, Schott JM, Walsh DM.

Alzheimers Dement. 2018 Nov 9. pii: S1552-5260(18)33561-1. doi: 10.1016/j.jalz.2018.09.010. [Epub ahead of print]

PMID:
30419228
6.

Association of Cerebrospinal Fluid Neurofilament Light Protein With Risk of Mild Cognitive Impairment Among Individuals Without Cognitive Impairment.

Kern S, Syrjanen JA, Blennow K, Zetterberg H, Skoog I, Waern M, Hagen CE, van Harten AC, Knopman DS, Jack CR Jr, Petersen RC, Mielke MM.

JAMA Neurol. 2018 Nov 12. doi: 10.1001/jamaneurol.2018.3459. [Epub ahead of print]

PMID:
30419087
7.

Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer's disease.

Sánchez-Valle R, Heslegrave A, Foiani MS, Bosch B, Antonell A, Balasa M, Lladó A, Zetterberg H, Fox NC.

Alzheimers Res Ther. 2018 Nov 3;10(1):113. doi: 10.1186/s13195-018-0439-y.

8.

CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau.

Henjum K, Quist-Paulsen E, Zetterberg H, Blennow K, Nilsson LNG, Watne LO.

J Neuroinflammation. 2018 Nov 3;15(1):304. doi: 10.1186/s12974-018-1331-1.

9.

Serum Neurofilament Light Chain for Prognosis of Outcome After Cardiac Arrest.

Moseby-Knappe M, Mattsson N, Nielsen N, Zetterberg H, Blennow K, Dankiewicz J, Dragancea I, Friberg H, Lilja G, Insel PS, Rylander C, Westhall E, Kjaergaard J, Wise MP, Hassager C, Kuiper MA, Stammet P, Wanscher MCJ, Wetterslev J, Erlinge D, Horn J, Pellis T, Cronberg T.

JAMA Neurol. 2018 Oct 29. doi: 10.1001/jamaneurol.2018.3223. [Epub ahead of print]

PMID:
30383090
10.

Early predictors of mortality in parkinsonism and Parkinson disease: A population-based study.

Bäckström D, Granåsen G, Domellöf ME, Linder J, Jakobson Mo S, Riklund K, Zetterberg H, Blennow K, Forsgren L.

Neurology. 2018 Oct 31. pii: 10.1212/WNL.0000000000006576. doi: 10.1212/WNL.0000000000006576. [Epub ahead of print]

PMID:
30381367
11.

Protofibrillar and Fibrillar Amyloid-β Binding Proteins in Cerebrospinal Fluid.

Rahman MM, Westermark GT, Zetterberg H, Härd T, Sandgren M.

J Alzheimers Dis. 2018 Oct 23. doi: 10.3233/JAD-180596. [Epub ahead of print]

PMID:
30372682
12.

No change in plasma tau and serum neurofilament light concentrations in adolescent athletes following sport-related concussion.

Wallace C, Zetterberg H, Blennow K, van Donkelaar P.

PLoS One. 2018 Oct 29;13(10):e0206466. doi: 10.1371/journal.pone.0206466. eCollection 2018.

13.

Accurate risk estimation of β-amyloid positivity to identify prodromal Alzheimer's disease: Cross-validation study of practical algorithms.

Palmqvist S, Insel PS, Zetterberg H, Blennow K, Brix B, Stomrud E; Alzheimer's Disease Neuroimaging Initiative; Swedish BioFINDER study, Mattsson N, Hansson O.

Alzheimers Dement. 2018 Oct 23. pii: S1552-5260(18)33524-6. doi: 10.1016/j.jalz.2018.08.014. [Epub ahead of print]

14.

Blood-based biomarkers for Alzheimer's disease - an update.

Zetterberg H.

J Neurosci Methods. 2018 Oct 20. pii: S0165-0270(18)30339-X. doi: 10.1016/j.jneumeth.2018.10.025. [Epub ahead of print]

PMID:
30352211
15.

Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons.

Nazir FH, Becker B, Brinkmalm A, Höglund K, Sandelius Å, Bergström P, Satir TM, Öhrfelt A, Blennow K, Agholme L, Zetterberg H.

Neurochem Int. 2018 Dec;121:38-49. doi: 10.1016/j.neuint.2018.10.014. Epub 2018 Oct 18.

16.

Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.

Sandelius Å, Portelius E, Källén Å, Zetterberg H, Rot U, Olsson B, Toledo JB, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, Kostanjevecki V, Vandijck M, McBride J, Trojanowski JQ, Blennow K.

Alzheimers Dement. 2018 Oct 12. pii: S1552-5260(18)33515-5. doi: 10.1016/j.jalz.2018.08.006. [Epub ahead of print]

17.

Vitamin D supplementation and neurofilament light chain in multiple sclerosis.

Holmøy T, Røsjø E, Zetterberg H, Blennow K, Lindstrøm JC, Steffensen LH, Kampman MT.

Acta Neurol Scand. 2018 Oct 13. doi: 10.1111/ane.13037. [Epub ahead of print]

PMID:
30317548
18.

Intrathecal treatment trial of rituximab in progressive MS: An open-label phase 1b study.

Bergman J, Burman J, Gilthorpe JD, Zetterberg H, Jiltsova E, Bergenheim T, Svenningsson A.

Neurology. 2018 Nov 13;91(20):e1893-e1901. doi: 10.1212/WNL.0000000000006500. Epub 2018 Oct 10.

PMID:
30305449
19.

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic.

Hampel H, O'Bryant SE, Molinuevo JL, Zetterberg H, Masters CL, Lista S, Kiddle SJ, Batrla R, Blennow K.

Nat Rev Neurol. 2018 Nov;14(11):639-652. doi: 10.1038/s41582-018-0079-7. Review.

PMID:
30297701
20.

Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration.

Strømme P, Groeneweg S, Lima de Souza EC, Zevenbergen C, Torgersbråten A, Holmgren A, Gurcan E, Meima ME, Peeters RP, Visser WE, Høneren Johansson L, Babovic A, Zetterberg H, Heuer H, Frengen E, Misceo D, Visser TJ.

Thyroid. 2018 Nov;28(11):1406-1415. doi: 10.1089/thy.2018.0595.

PMID:
30296914
21.

Interlaboratory validation of cerebrospinal fluid α-synuclein quantification in the diagnosis of sporadic Creutzfeldt-Jakob disease.

Kruse N, Heslegrave A, Gupta V, Foiani M, Villar-Piqué A, Schmitz M, Lehmann S, Teunissen C, Blennow K, Zetterberg H, Mollenhauer B, Zerr I, Llorens F.

Alzheimers Dement (Amst). 2018 Jul 7;10:461-470. doi: 10.1016/j.dadm.2018.06.005. eCollection 2018.

22.

CSF pro-orexin and amyloid-β38 expression in Alzheimer's disease and frontotemporal dementia.

Heywood WE, Hallqvist J, Heslegrave AJ, Zetterberg H, Fenoglio C, Scarpini E, Rohrer JD, Galimberti D, Mills K.

Neurobiol Aging. 2018 Dec;72:171-176. doi: 10.1016/j.neurobiolaging.2018.08.019. Epub 2018 Aug 25.

23.

GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology.

Michno W, Wehrli PM, Zetterberg H, Blennow K, Hanrieder J.

Biochim Biophys Acta Proteins Proteom. 2018 Sep 28. pii: S1570-9639(18)30164-X. doi: 10.1016/j.bbapap.2018.09.010. [Epub ahead of print]

PMID:
30273679
24.

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study.

Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R, Gabel S, Schaeverbeke J, Scheltens P, Blin O, Richardson JC, Bordet R, Wallin A, Eckerstrom C, Molinuevo JL, Engelborghs S, Van Broeckhoven C, Martinez-Lage P, Popp J, Tsolaki M, Verhey FRJ, Baird AL, Legido-Quigley C, Bertram L, Dobricic V, Zetterberg H, Lovestone S, Streffer J, Bianchetti S, Novak GP, Revillard J, Gordon MF, Xie Z, Wottschel V, Frisoni G, Visser PJ, Barkhof F.

Alzheimers Res Ther. 2018 Sep 27;10(1):100. doi: 10.1186/s13195-018-0428-1.

25.

Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery-a randomized trial.

Danielson M, Reinsfelt B, Westerlind A, Zetterberg H, Blennow K, Ricksten SE.

J Neuroinflammation. 2018 Sep 27;15(1):283. doi: 10.1186/s12974-018-1318-y.

26.

Parkinson's disease: evolution of cognitive impairment and CSF Aβ1-42 profiles in a prospective longitudinal study.

Lerche S, Wurster I, Röben B, Machetanz G, Zimmermann M, Bernhard F, Stransky E, Deuschle C, Schulte C, Hansson O, Zetterberg H, Gasser T, Berg D, Maetzler W, Brockmann K.

J Neurol Neurosurg Psychiatry. 2018 Sep 25. pii: jnnp-2018-318956. doi: 10.1136/jnnp-2018-318956. [Epub ahead of print]

PMID:
30254084
27.

Abnormal CSF amyloid-β42 and tau levels in hip fracture patients without dementia.

Oh ES, Blennow K, Bigelow GE, Inouye SK, Marcantonio ER, Neufeld KJ, Rosenberg PB, Troncoso JC, Wang NY, Zetterberg H, Sieber FE, Lyketsos CG.

PLoS One. 2018 Sep 25;13(9):e0204695. doi: 10.1371/journal.pone.0204695. eCollection 2018. Erratum in: PLoS One. 2018 Oct 26;13(10):e0206719.

28.

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.

Kvartsberg H, Lashley T, Murray CE, Brinkmalm G, Cullen NC, Höglund K, Zetterberg H, Blennow K, Portelius E.

Acta Neuropathol. 2018 Sep 22. doi: 10.1007/s00401-018-1910-3. [Epub ahead of print]

PMID:
30244311
29.

Fluid-based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases.

Brinkmalm A, Portelius E, Brinkmalm G, Pannee J, Dahlén R, Gobom J, Blennow K, Zetterberg H.

J Neurochem. 2018 Sep 20. doi: 10.1111/jnc.14594. [Epub ahead of print] Review.

PMID:
30238462
30.

Heading in soccer increases serum neurofilament light protein and SCAT3 symptom metrics.

Wallace C, Smirl JD, Zetterberg H, Blennow K, Bryk K, Burma J, Dierijck J, Wright AD, van Donkelaar P.

BMJ Open Sport Exerc Med. 2018 Aug 27;4(1):e000433. doi: 10.1136/bmjsem-2018-000433. eCollection 2018.

31.

Integration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis.

Herman S, Khoonsari PE, Tolf A, Steinmetz J, Zetterberg H, Åkerfeldt T, Jakobsson PJ, Larsson A, Spjuth O, Burman J, Kultima K.

Theranostics. 2018 Aug 7;8(16):4477-4490. doi: 10.7150/thno.26249. eCollection 2018.

32.

Stability of blood-based biomarkers of Alzheimer's disease over multiple freeze-thaw cycles.

Keshavan A, Heslegrave A, Zetterberg H, Schott JM.

Alzheimers Dement (Amst). 2018 Jul 2;10:448-451. doi: 10.1016/j.dadm.2018.06.001. eCollection 2018.

33.

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.

Byrne LM, Rodrigues FB, Johnson EB, Wijeratne PA, De Vita E, Alexander DC, Palermo G, Czech C, Schobel S, Scahill RI, Heslegrave A, Zetterberg H, Wild EJ.

Sci Transl Med. 2018 Sep 12;10(458). pii: eaat7108. doi: 10.1126/scitranslmed.aat7108.

PMID:
30209243
34.

Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer's Disease: A Pilot Study.

Koychev I, Galna B, Zetterberg H, Lawson J, Zamboni G, Ridha BH, Rowe JB, Thomas A, Howard R, Malhotra P, Ritchie C, Lovestone S, Rochester L.

J Alzheimers Dis. 2018;65(4):1377-1383. doi: 10.3233/JAD-180622.

35.

Inflammatory markers of CHMP2B-mediated frontotemporal dementia.

Roos P, von Essen MR, Nielsen TT, Johannsen P, Stokholm J, Bie AS, Waldemar G, Simonsen AH, Heslegrave A, Zetterberg H; FReJA consortium, Sellebjerg F, Nielsen JE.

J Neuroimmunol. 2018 Nov 15;324:136-142. doi: 10.1016/j.jneuroim.2018.08.009. Epub 2018 Aug 17.

PMID:
30193769
36.

Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species.

Oliveira F, Leuzy A, Castelhano J, Chiotis K, Hasselbalch SG, Rinne J, Mendonça A, Otto M, Lleó A, Santana I, Johansson J, Anderl-Straub S, Arnim C, Beer A, Blesa R, Fortea J, Sanna-Kaisa H, Portelius E, Pannee J, Zetterberg H, Blennow K, Moreira AP, Abrunhosa A, Nordberg A, Castelo-Branco M.

Neuroimage Clin. 2018 Aug 19;20:603-610. doi: 10.1016/j.nicl.2018.08.023. eCollection 2018.

37.

Cerebrospinal fluid concentrations of inflammatory markers in Parkinson's disease and atypical parkinsonian disorders.

Hall S, Janelidze S, Surova Y, Widner H, Zetterberg H, Hansson O.

Sci Rep. 2018 Sep 5;8(1):13276. doi: 10.1038/s41598-018-31517-z.

38.

Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain Barrier.

Delsing L, Dönnes P, Sánchez J, Clausen M, Voulgaris D, Falk A, Herland A, Brolén G, Zetterberg H, Hicks R, Synnergren J.

Stem Cells. 2018 Sep 1. doi: 10.1002/stem.2908. [Epub ahead of print]

PMID:
30171748
39.

Neurofilaments as biomarkers in neurological disorders.

Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, Barro C, Kappos L, Comabella M, Fazekas F, Petzold A, Blennow K, Zetterberg H, Kuhle J.

Nat Rev Neurol. 2018 Oct;14(10):577-589. doi: 10.1038/s41582-018-0058-z. Review.

PMID:
30171200
40.

Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase.

Becker B, Nazir FH, Brinkmalm G, Camporesi E, Kvartsberg H, Portelius E, Boström M, Kalm M, Höglund K, Olsson M, Zetterberg H, Blennow K.

Mol Neurodegener. 2018 Aug 29;13(1):47. doi: 10.1186/s13024-018-0279-z.

41.

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis.

Garcia-Reitboeck P, Phillips A, Piers TM, Villegas-Llerena C, Butler M, Mallach A, Rodrigues C, Arber CE, Heslegrave A, Zetterberg H, Neumann H, Neame S, Houlden H, Hardy J, Pocock JM.

Cell Rep. 2018 Aug 28;24(9):2300-2311. doi: 10.1016/j.celrep.2018.07.094.

42.

Midlife Stress in Relation to Late-Life Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: A 25-Year Follow-Up Study.

Johansson L, Kern S, Zetterberg H, Blennow K, Börjesson-Hansson A, Rosengren L, Guo X, Skoog I.

Dement Geriatr Cogn Disord. 2018;46(1-2):90-99. doi: 10.1159/000490885. Epub 2018 Aug 24.

PMID:
30145588
43.

Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid - method comparison and round robin study.

Mollenhauer B, Bowman FD, Drake D, Duong J, Blennow K, El-Agnaf O, Shaw LM, Masucci J, Taylor P, Umek RM, Dunty JM, Smith CL, Stoops E, Vanderstichele H, Schmid AW, Moniatte M, Zhang J, Kruse N, Lashuel HA, Teunissen C, Schubert T, Dave KD, Hutten SJ, Zetterberg H.

J Neurochem. 2018 Aug 20. doi: 10.1111/jnc.14569. [Epub ahead of print]

PMID:
30125936
44.

Biomarkers for Antidepressant Efficacy of Electroconvulsive Therapy: An Exploratory Cerebrospinal Fluid Study.

Kranaster L, Hoyer C, Aksay SS, Bumb JM, Müller N, Zill P, Schwarz MJ, Moll N, Lutz B, Bindila L, Zerr I, Schmitz M, Blennow K, Zetterberg H, Haffner D, Leifheit-Nestler M, Ozbalci C, Janke C, Thiel M, Sartorius A.

Neuropsychobiology. 2018 Aug 17:1-10. doi: 10.1159/000491401. [Epub ahead of print]

PMID:
30121652
45.

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup.

Woollacott IOC, Nicholas JM, Heslegrave A, Heller C, Foiani MS, Dick KM, Russell LL, Paterson RW, Keshavan A, Fox NC, Warren JD, Schott JM, Zetterberg H, Rohrer JD.

Alzheimers Res Ther. 2018 Aug 16;10(1):79. doi: 10.1186/s13195-018-0405-8.

46.

Effects of APOE ε4 on neuroimaging, cerebrospinal fluid biomarkers, and cognition in prodromal Alzheimer's disease.

Mattsson N, Eriksson O, Lindberg O, Schöll M, Lampinen B, Nilsson M, Insel PS, Lautner R, Strandberg O, van Westen D, Zetterberg H, Blennow K, Palmqvist S, Stomrud E, Hansson O.

Neurobiol Aging. 2018 Nov;71:81-90. doi: 10.1016/j.neurobiolaging.2018.07.003. Epub 2018 Jul 11.

PMID:
30107289
47.

Neurofilament light chain in blood is negatively associated with neuropsychological performance in HIV-infected adults and declines with initiation of antiretroviral therapy.

Anderson AM, Easley KA, Kasher N, Franklin D, Heaton RK, Zetterberg H, Blennow K, Gisslen M, Letendre SL.

J Neurovirol. 2018 Aug 13. doi: 10.1007/s13365-018-0664-y. [Epub ahead of print]

PMID:
30105502
48.

Cerebrospinal fluid GAP-43 in early multiple sclerosis.

Rot U, Sandelius Å, Emeršič A, Zetterberg H, Blennow K.

Mult Scler J Exp Transl Clin. 2018 Aug 7;4(3):2055217318792931. doi: 10.1177/2055217318792931. eCollection 2018 Jul-Sep.

49.

Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution.

Taylor CG, Meisl G, Horrocks MH, Zetterberg H, Knowles TPJ, Klenerman D.

Anal Chem. 2018 Sep 4;90(17):10385-10393. doi: 10.1021/acs.analchem.8b02226. Epub 2018 Aug 13.

50.

Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease.

Lewczuk P, Ermann N, Andreasson U, Schultheis C, Podhorna J, Spitzer P, Maler JM, Kornhuber J, Blennow K, Zetterberg H.

Alzheimers Res Ther. 2018 Jul 28;10(1):71. doi: 10.1186/s13195-018-0404-9.

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