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Items: 1 to 50 of 887

1.

Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease.

Hao L, Wang J, Page D, Asthana S, Zetterberg H, Carlsson C, Okonkwo OC, Li L.

Sci Rep. 2018 Jun 18;8(1):9291. doi: 10.1038/s41598-018-27031-x.

2.

A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence?

Casaletto KB, Elahi FE, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher B, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH.

Cytokine. 2018 Jun 13. pii: S1043-4666(18)30226-6. doi: 10.1016/j.cyto.2018.05.032. [Epub ahead of print]

PMID:
29908923
3.

Neurofilament light chain as disease biomarker in a rodent model of chemotherapy induced peripheral neuropathy.

Meregalli C, Fumagalli G, Alberti P, Canta A, Carozzi VA, Chiorazzi A, Monza L, Pozzi E, Sandelius Å, Blennow K, Zetterberg H, Marmiroli P, Cavaletti G.

Exp Neurol. 2018 Jun 13. pii: S0014-4886(18)30189-4. doi: 10.1016/j.expneurol.2018.06.005. [Epub ahead of print]

PMID:
29908147
4.

Update on biomarkers for amyloid pathology in Alzheimer's disease.

Ashton NJ, Schöll M, Heurling K, Gkanatsiou E, Portelius E, Höglund K, Brinkmalm G, Hye A, Blennow K, Zetterberg H.

Biomark Med. 2018 Jun 15. doi: 10.2217/bmm-2017-0433. [Epub ahead of print]

PMID:
29902934
5.

S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.

Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Helin S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO.

J Alzheimers Dis. 2018;64(1):171-179. doi: 10.3233/JAD-180071.

PMID:
29865068
6.

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.

Michno W, Kaya I, Nyström S, Guerard L, Nilsson KPR, Hammarström P, Blennow K, Zetterberg H, Hanrieder J.

Anal Chem. 2018 Jun 19. doi: 10.1021/acs.analchem.8b01361. [Epub ahead of print]

PMID:
29856605
7.

New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia.

Khachaturian AS, Hayden KM, Mielke MM, Tang Y, Lutz MW, Gold M, Kukull WA, Mohs R, Gauthier S, Molinuevo JL, Zetterberg H, Khachaturian ZS.

Alzheimers Dement. 2018 Jun;14(6):703-706. doi: 10.1016/j.jalz.2018.05.002. Epub 2018 May 26. No abstract available.

PMID:
29842864
8.

Validity and Normative Data for the Biber Figure Learning Test: A Visual Supraspan Memory Measure.

Gifford KA, Liu D, Neal JE, Acosta LMY, Bell SP, Wiggins ME, Wisniewski KM, Godfrey M, Logan LA, Hohman TJ, Pechman KR, Libon DJ, Blennow K, Zetterberg H, Jefferson AL.

Assessment. 2018 May 1:1073191118773870. doi: 10.1177/1073191118773870. [Epub ahead of print]

PMID:
29809069
9.

Biomarkers in cerebrospinal fluid of patients with bipolar disorder versus healthy individuals: A systematic review.

Knorr U, Simonsen AH, Zetterberg H, Blennow K, Hasselbalch SG, Kessing LV.

Eur Neuropsychopharmacol. 2018 May 22. pii: S0924-977X(18)30110-X. doi: 10.1016/j.euroneuro.2018.04.002. [Epub ahead of print] Review.

PMID:
29802040
10.

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL; Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2018 May 7. doi: 10.1001/jamaneurol.2018.0821. [Epub ahead of print]

PMID:
29801024
11.

Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios.

Toombs J, Foiani MS, Wellington H, Paterson RW, Arber C, Heslegrave A, Lunn MP, Schott JM, Wray S, Zetterberg H.

Alzheimers Dement (Amst). 2018 Mar 22;10:311-321. doi: 10.1016/j.dadm.2018.02.005. eCollection 2018.

12.

A 10-Year Follow-Up of Adiposity and Dementia in Swedish Adults Aged 70 Years and Older.

Arnoldussen IAC, Sundh V, Bäckman K, Kern S, Östling S, Blennow K, Zetterberg H, Skoog I, Kiliaan AJ, Gustafson DR.

J Alzheimers Dis. 2018;63(4):1325-1335. doi: 10.3233/JAD-180099.

PMID:
29758945
13.

From Cerebrospinal Fluid to Blood: The Third Wave of Fluid Biomarkers for Alzheimer's Disease.

Zetterberg H, Blennow K.

J Alzheimers Dis. 2018;64(s1):S271-S279. doi: 10.3233/JAD-179926.

PMID:
29758941
14.

High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden Study.

Kristjansdottir HL, Lewerin C, Lerner UH, Waern E, Johansson H, Sundh D, Karlsson M, Cummings SR, Zetterberg H, Lorentzon M, Ohlsson C, Mellström D.

J Bone Miner Res. 2018 May 11. doi: 10.1002/jbmr.3443. [Epub ahead of print]

PMID:
29750841
15.

Reduced penetrance of the PSEN1 H163Y autosomal dominant Alzheimer mutation: a 22-year follow-up study.

Thordardottir S, Rodriguez-Vieitez E, Almkvist O, Ferreira D, Saint-Aubert L, Kinhult-Ståhlbom A, Thonberg H, Schöll M, Westman E, Wall A, Eriksdotter M, Zetterberg H, Blennow K, Nordberg A, Graff C.

Alzheimers Res Ther. 2018 May 10;10(1):45. doi: 10.1186/s13195-018-0374-y.

16.

Molecular biomarkers of Alzheimer's disease: progress and prospects.

Lashley T, Schott JM, Weston P, Murray CE, Wellington H, Keshavan A, Foti SC, Foiani M, Toombs J, Rohrer JD, Heslegrave A, Zetterberg H.

Dis Model Mech. 2018 May 8;11(5). pii: dmm031781. doi: 10.1242/dmm.031781. Review.

17.

Blood-based cerebral biomarkers in preeclampsia: Plasma concentrations of NfL, tau, S100B and NSE during pregnancy in women who later develop preeclampsia - A nested case control study.

Bergman L, Zetterberg H, Kaihola H, Hagberg H, Blennow K, Åkerud H.

PLoS One. 2018 May 2;13(5):e0196025. doi: 10.1371/journal.pone.0196025. eCollection 2018.

18.

Cerebrospinal fluid β-amyloid42 and neurofilament light relate to white matter hyperintensities.

Osborn KE, Liu D, Samuels LR, Moore EE, Cambronero FE, Acosta LMY, Bell SP, Babicz MA, Gordon EA, Pechman KR, Davis LT, Gifford KA, Hohman TJ, Blennow K, Zetterberg H, Jefferson AL.

Neurobiol Aging. 2018 Aug;68:18-25. doi: 10.1016/j.neurobiolaging.2018.03.028. Epub 2018 Apr 3.

PMID:
29702372
19.

Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology.

Portelius E, Olsson B, Höglund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius Å, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, McBride J, Toledo JB, Trojanowski JQ, Blennow K.

Acta Neuropathol. 2018 Apr 26. doi: 10.1007/s00401-018-1851-x. [Epub ahead of print]

PMID:
29700597
20.

Longitudinal Trajectories of Brain Volume and Cortical Thickness in Treated and Untreated Primary HIV Infection.

Sanford R, Ances BM, Meyerhoff DJ, Price RW, Fuchs D, Zetterberg H, Spudich S, Collins DL.

Clin Infect Dis. 2018 Apr 24. doi: 10.1093/cid/ciy362. [Epub ahead of print]

PMID:
29697762
21.

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS.

Novakova L, Singh AK, Malmeström C, Zetterberg H, Ståhlman M, Axelsson M, Adiels M, Borén J, Lycke J, Cardell SL, Blomqvist M.

J Neurochem. 2018 Apr 20. doi: 10.1111/jnc.14452. [Epub ahead of print]

PMID:
29676479
22.

Cerebrospinal fluid markers of extracellular matrix remodelling, synaptic plasticity and neuroinflammation before and after cranial radiotherapy.

Fernström E, Minta K, Andreasson U, Sandelius Å, Wasling P, Brinkmalm A, Höglund K, Blennow K, Nyman J, Zetterberg H, Kalm M.

J Intern Med. 2018 Apr 17. doi: 10.1111/joim.12763. [Epub ahead of print]

PMID:
29664192
23.

Neurofilament light and tau as blood biomarkers for sports-related concussion.

Shahim P, Tegner Y, Marklund N, Blennow K, Zetterberg H.

Neurology. 2018 May 15;90(20):e1780-e1788. doi: 10.1212/WNL.0000000000005518. Epub 2018 Apr 13.

24.

Prevalence of preclinical Alzheimer disease: Comparison of current classification systems.

Kern S, Zetterberg H, Kern J, Zettergren A, Waern M, Höglund K, Andreasson U, Wetterberg H, Börjesson-Hanson A, Blennow K, Skoog I.

Neurology. 2018 May 8;90(19):e1682-e1691. doi: 10.1212/WNL.0000000000005476. Epub 2018 Apr 13.

25.

Commentary: Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Karikari TK, Charway-Felli A, Höglund K, Blennow K, Zetterberg H.

Front Neurol. 2018 Mar 29;9:201. doi: 10.3389/fneur.2018.00201. eCollection 2018. No abstract available.

26.

Shedding Light on the Molecular Pathology of Amyloid Plaques in Transgenic Alzheimer's Disease Mice Using Multimodal MALDI Imaging Mass Spectrometry.

Kaya I, Zetterberg H, Blennow K, Hanrieder J.

ACS Chem Neurosci. 2018 May 4. doi: 10.1021/acschemneuro.8b00121. [Epub ahead of print]

PMID:
29648443
27.

Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome.

Strydom A, Heslegrave A, Startin CM, Mok KY, Hardy J, Groet J, Nizetic D, Zetterberg H; LonDownS Consortium.

Alzheimers Res Ther. 2018 Apr 10;10(1):39. doi: 10.1186/s13195-018-0367-x.

28.

Association of Plasma Neurofilament Light Chain with Neocortical Amyloid-β Load and Cognitive Performance in Cognitively Normal Elderly Participants.

Chatterjee P, Goozee K, Sohrabi HR, Shen K, Shah T, Asih PR, Dave P, ManYan C, Taddei K, Chung R, Zetterberg H, Blennow K, Martins RN.

J Alzheimers Dis. 2018;63(2):479-487. doi: 10.3233/JAD-180025.

PMID:
29630554
29.

Neurofilament light protein levels in cerebrospinal fluid predict long-term disability of Guillain-Barré syndrome: A pilot study.

Axelsson M, Sjögren M, Andersen O, Blennow K, Zetterberg H, Lycke J.

Acta Neurol Scand. 2018 Apr 6. doi: 10.1111/ane.12927. [Epub ahead of print]

PMID:
29624650
30.

Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study.

Mc Ardle R, Morris R, Hickey A, Del Din S, Koychev I, Gunn RN, Lawson J, Zamboni G, Ridha B, Sahakian BJ, Rowe JB, Thomas A, Zetterberg H, MacKay C, Lovestone S, Rochesteron L; Deep and Frequent Phenotyping study team (.

J Alzheimers Dis. 2018;63(1):331-341. doi: 10.3233/JAD-171116.

PMID:
29614664
31.

Low Cerebrospinal Fluid Aβ42 and Aβ40 are Related to White Matter Lesions in Cognitively Normal Elderly.

Skoog I, Kern S, Zetterberg H, Östling S, Börjesson-Hanson A, Guo X, Blennow K.

J Alzheimers Dis. 2018;62(4):1877-1886. doi: 10.3233/JAD-170950.

32.

Plasma Amyloid-β (Aβ42) Correlates with Cerebrospinal Fluid Aβ42 in Alzheimer's Disease.

Teunissen CE, Chiu MJ, Yang CC, Yang SY, Scheltens P, Zetterberg H, Blennow K.

J Alzheimers Dis. 2018;62(4):1857-1863. doi: 10.3233/JAD-170784.

PMID:
29614646
33.

Searching for neurodegeneration in multiple sclerosis at clinical onset: Diagnostic value of biomarkers.

Novakova L, Axelsson M, Malmeström C, Imberg H, Elias O, Zetterberg H, Nerman O, Lycke J.

PLoS One. 2018 Apr 3;13(4):e0194828. doi: 10.1371/journal.pone.0194828. eCollection 2018.

34.

Longitudinal performance of plasma neurofilament light and tau in professional fighters: The Professional Fighters Brain Health Study.

Bernick C, Zetterberg H, Shan G, Banks S, Blennow K.

J Neurotrauma. 2018 Apr 2. doi: 10.1089/neu.2017.5553. [Epub ahead of print]

PMID:
29609512
35.

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Mattsson N, Groot C, Jansen WJ, Landau SM, Villemagne VL, Engelborghs S, Mintun MM, Lleo A, Molinuevo JL, Jagust WJ, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, Kornhuber J, Wallin A, Klimkowicz-Mrowiec A, Kandimalla R, Popp J, Aalten PP, Aarsland D, Alcolea D, Almdahl IS, Baldeiras I, van Buchem MA, Cavedo E, Chen K, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gill KD, Gkatzima O, Grimmer T, Hampel H, Herukka SK, Johannsen P, van Laere K, de Leon MJ, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Mroczko B, Nordlund A, Prabhakar S, Peters O, Rami L, Rodríguez-Rodríguez E, Roe CM, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Verhey FRJ, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Vandenberghe R, Brooks DJ, Fladby T, Rowe CC, Drzezga A, Verbeek MM, Sarazin M, Wolk DA, Fleisher AS, Klunk WE, Na DL, Sánchez-Juan P, Lee DY, Nordberg A, Tsolaki M, Camus V, Rinne JO, Fagan AM, Zetterberg H, Blennow K, Rabinovici GD, Hansson O, van Berckel BNM, van der Flier WM, Scheltens P, Visser PJ, Ossenkoppele R.

Alzheimers Dement. 2018 Mar 28. pii: S1552-5260(18)30063-3. doi: 10.1016/j.jalz.2018.02.009. [Epub ahead of print]

PMID:
29601787
36.

Tauomics and Kinetics in Human Neurons and Biological Fluids.

Zetterberg H.

Neuron. 2018 Mar 21;97(6):1202-1205. doi: 10.1016/j.neuron.2018.02.030.

PMID:
29566788
37.

The Past and the Future of Alzheimer's Disease Fluid Biomarkers.

Blennow K, Zetterberg H.

J Alzheimers Dis. 2018;62(3):1125-1140. doi: 10.3233/JAD-170773.

38.

Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.

Paterson RW, Slattery CF, Poole T, Nicholas JM, Magdalinou NK, Toombs J, Chapman MD, Lunn MP, Heslegrave AJ, Foiani MS, Weston PSJ, Keshavan A, Rohrer JD, Rossor MN, Warren JD, Mummery CJ, Blennow K, Fox NC, Zetterberg H, Schott JM.

Alzheimers Res Ther. 2018 Mar 20;10(1):32. doi: 10.1186/s13195-018-0361-3.

39.

Apolipoprotein E genotypes and longevity across dementia disorders.

Skillbäck T, Lautner R, Mattsson N, Schott JM, Skoog I, Nägga K, Kilander L, Wimo A, Winblad B, Eriksdotter M, Blennow K, Zetterberg H.

Alzheimers Dement. 2018 Mar 13. pii: S1552-5260(18)30045-1. doi: 10.1016/j.jalz.2018.02.003. [Epub ahead of print]

PMID:
29548722
40.

White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation.

Teunissen CE, Otto M, Engelborghs S, Herukka SK, Lehmann S, Lewczuk P, Lleó A, Perret-Liaudet A, Tumani H, Turner MR, Verbeek MM, Wiltfang J, Zetterberg H, Parnetti L, Blennow K.

Alzheimers Res Ther. 2018 Mar 15;10(1):30. doi: 10.1186/s13195-018-0359-x. Review.

41.

Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer's disease.

Law LL, Rol RN, Schultz SA, Dougherty RJ, Edwards DF, Koscik RL, Gallagher CL, Carlsson CM, Bendlin BB, Zetterberg H, Blennow K, Asthana S, Sager MA, Hermann BP, Johnson SC, Cook DB, Okonkwo OC.

Alzheimers Dement (Amst). 2018 Feb 6;10:188-195. doi: 10.1016/j.dadm.2018.01.001. eCollection 2018.

42.

Cerebrospinal fluid neurogranin and TREM2 in Huntington's disease.

Byrne LM, Rodrigues FB, Johnson EB, De Vita E, Blennow K, Scahill R, Zetterberg H, Heslegrave A, Wild EJ.

Sci Rep. 2018 Mar 9;8(1):4260. doi: 10.1038/s41598-018-21788-x.

43.

Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid.

Clark LR, Berman SE, Norton D, Koscik RL, Jonaitis E, Blennow K, Bendlin BB, Asthana S, Johnson SC, Zetterberg H, Carlsson CM.

Neurology. 2018 Apr 10;90(15):e1306-e1315. doi: 10.1212/WNL.0000000000005291. Epub 2018 Mar 9.

PMID:
29523644
44.

Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study.

Willemse EAJ, De Vos A, Herries EM, Andreasson U, Engelborghs S, van der Flier WM, Scheltens P, Crimmins D, Ladenson JH, Vanmechelen E, Zetterberg H, Fagan AM, Blennow K, Bjerke M, Teunissen CE.

Clin Chem. 2018 Jun;64(6):927-937. doi: 10.1373/clinchem.2017.283028. Epub 2018 Mar 9.

PMID:
29523639
45.

Nutritional Supplements for the Treatment and Prevention of Sports-Related Concussion - Omega 3 Fatty Acids: Evidence Still Lacking?

Oliver JM, Anzalone AJ, Jones MT, Kirk KM, Gable DA, Gao Y, Harris WS, Zetterberg H.

Curr Sports Med Rep. 2018 Mar;17(3):103-104. doi: 10.1249/JSR.0000000000000465. No abstract available.

PMID:
29521707
46.

Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides.

Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Haber VE, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L.

J Alzheimers Dis. 2018;62(4):1663-1681. doi: 10.3233/JAD-170875.

PMID:
29504531
47.

CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts.

Hansson O, Seibyl J, Stomrud E, Zetterberg H, Trojanowski JQ, Bittner T, Lifke V, Corradini V, Eichenlaub U, Batrla R, Buck K, Zink K, Rabe C, Blennow K, Shaw LM; Swedish BioFINDER study group; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2018 Mar 1. pii: S1552-5260(18)30029-3. doi: 10.1016/j.jalz.2018.01.010. [Epub ahead of print]

48.

Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression.

Thompson AGB, Luk C, Heslegrave AJ, Zetterberg H, Mead SH, Collinge J, Jackson GS.

J Neurol Neurosurg Psychiatry. 2018 Feb 27. pii: jnnp-2017-317793. doi: 10.1136/jnnp-2017-317793. [Epub ahead of print]

49.

Cerebrospinal fluid sCD27 levels indicate active T cell-mediated inflammation in premanifest Huntington's disease.

Niemelä V, Burman J, Blennow K, Zetterberg H, Larsson A, Sundblom J.

PLoS One. 2018 Feb 23;13(2):e0193492. doi: 10.1371/journal.pone.0193492. eCollection 2018.

50.

CSF neurogranin or tau distinguish typical and atypical Alzheimer disease.

Wellington H, Paterson RW, Suárez-González A, Poole T, Frost C, Sjöbom U, Slattery CF, Magdalinou NK, Lehmann M, Portelius E, Fox NC, Blennow K, Zetterberg H, Schott JM.

Ann Clin Transl Neurol. 2018 Jan 11;5(2):162-171. doi: 10.1002/acn3.518. eCollection 2018 Feb.

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