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Items: 41


β-Amyloid Aggregation and Heterogeneous Nucleation.

Srivastava AK, Pittman JM, Zerweck J, Venkata BS, Moore PC, Sachleben JR, Meredith SC.

Protein Sci. 2019 Jul 5. doi: 10.1002/pro.3674. [Epub ahead of print] Review.


Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning.

Gessulat S, Schmidt T, Zolg DP, Samaras P, Schnatbaum K, Zerweck J, Knaute T, Rechenberger J, Delanghe B, Huhmer A, Reimer U, Ehrlich HC, Aiche S, Kuster B, Wilhelm M.

Nat Methods. 2019 Jun;16(6):509-518. doi: 10.1038/s41592-019-0426-7. Epub 2019 May 27.


Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence.

Nadai Y, Held K, Joseph S, Ahmed MIM, Hoffmann VS, Peterhoff D, Missanga M, Bauer A, Joachim A, Reimer U, Zerweck J, McCormack S, Cope AV, Tatoud R, Shattock RJ, Robb ML, Sandstroem EG, Hoelscher M, Maboko L, Bakari M, Kroidl A, Wagner R, Weber J, Pollakis G, Geldmacher C.

Front Immunol. 2019 Apr 24;10:717. doi: 10.3389/fimmu.2019.00717. eCollection 2019.


A versatile method for producing labeled or unlabeled Aβ55, Aβ40, and other β-amyloid family peptides.

Zerweck J, Venkata BS, Pittman JM, Srivastava AK, Moore PC, Sachleben JR, Thinakaran G, Meredith SC.

Protein Expr Purif. 2019 Oct;162:72-82. doi: 10.1016/j.pep.2019.04.006. Epub 2019 Apr 22.


A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo.

Vormehr M, Reinhard K, Blatnik R, Josef K, Beck JD, Salomon N, Suchan M, Selmi A, Vascotto F, Zerweck J, Wenschuh H, Diken M, Kreiter S, Türeci Ö, Riemer AB, Sahin U.

Oncoimmunology. 2018 Dec 24;8(3):1553478. doi: 10.1080/2162402X.2018.1553478. eCollection 2019.


Analysis of Toxoplasma gondii clonal type-specific antibody reactions in experimentally infected turkeys and chickens.

Maksimov P, Basso W, Zerweck J, Schutkowski M, Reimer U, Maksimov A, Conraths FJ, Schares G.

Int J Parasitol. 2018 Sep;48(11):845-856. doi: 10.1016/j.ijpara.2018.04.004. Epub 2018 Jun 30.


ProteomeTools: Systematic Characterization of 21 Post-translational Protein Modifications by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Using Synthetic Peptides.

Zolg DP, Wilhelm M, Schmidt T, Médard G, Zerweck J, Knaute T, Wenschuh H, Reimer U, Schnatbaum K, Kuster B.

Mol Cell Proteomics. 2018 Sep;17(9):1850-1863. doi: 10.1074/mcp.TIR118.000783. Epub 2018 May 29.


Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2.

Zerweck J, Strandberg E, Kukharenko O, Reichert J, Bürck J, Wadhwani P, Ulrich AS.

Sci Rep. 2017 Oct 13;7(1):13153. doi: 10.1038/s41598-017-12599-7.


PROCAL: A Set of 40 Peptide Standards for Retention Time Indexing, Column Performance Monitoring, and Collision Energy Calibration.

Zolg DP, Wilhelm M, Yu P, Knaute T, Zerweck J, Wenschuh H, Reimer U, Schnatbaum K, Kuster B.

Proteomics. 2017 Nov;17(21). doi: 10.1002/pmic.201700263. Epub 2017 Oct 24.


Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.

Loebel M, Eckey M, Sotzny F, Hahn E, Bauer S, Grabowski P, Zerweck J, Holenya P, Hanitsch LG, Wittke K, Borchmann P, Rüffer JU, Hiepe F, Ruprecht K, Behrends U, Meindl C, Volk HD, Reimer U, Scheibenbogen C.

PLoS One. 2017 Jun 12;12(6):e0179124. doi: 10.1371/journal.pone.0179124. eCollection 2017.


Building ProteomeTools based on a complete synthetic human proteome.

Zolg DP, Wilhelm M, Schnatbaum K, Zerweck J, Knaute T, Delanghe B, Bailey DJ, Gessulat S, Ehrlich HC, Weininger M, Yu P, Schlegl J, Kramer K, Schmidt T, Kusebauch U, Deutsch EW, Aebersold R, Moritz RL, Wenschuh H, Moehring T, Aiche S, Huhmer A, Reimer U, Kuster B.

Nat Methods. 2017 Mar;14(3):259-262. doi: 10.1038/nmeth.4153. Epub 2017 Jan 30.


2H-NMR and MD Simulations Reveal Membrane-Bound Conformation of Magainin 2 and Its Synergy with PGLa.

Strandberg E, Horn D, Reißer S, Zerweck J, Wadhwani P, Ulrich AS.

Biophys J. 2016 Nov 15;111(10):2149-2161. doi: 10.1016/j.bpj.2016.10.012.


Antibody Responses After Analytic Treatment Interruption in Human Immunodeficiency Virus-1-Infected Individuals on Early Initiated Antiretroviral Therapy.

Stephenson KE, Neubauer GH, Bricault CA, Shields J, Bayne M, Reimer U, Pawlowski N, Knaute T, Zerweck J, Seaman MS, Rosenberg ES, Barouch DH.

Open Forum Infect Dis. 2016 May 19;3(2):ofw100. doi: 10.1093/ofid/ofw100. eCollection 2016 Apr.


Electrochemically assisted deposition of strontium modified magnesium phosphate on titanium surfaces.

Meininger M, Wolf-Brandstetter C, Zerweck J, Wenninger F, Gbureck U, Groll J, Moseke C.

Mater Sci Eng C Mater Biol Appl. 2016 Oct 1;67:65-71. doi: 10.1016/j.msec.2016.04.102. Epub 2016 May 4.


Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S.

J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5.


Homo- and heteromeric interaction strengths of the synergistic antimicrobial peptides PGLa and magainin 2 in membranes.

Zerweck J, Strandberg E, Bürck J, Reichert J, Wadhwani P, Kukharenko O, Ulrich AS.

Eur Biophys J. 2016 Sep;45(6):535-47. doi: 10.1007/s00249-016-1120-7. Epub 2016 Apr 6.


PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation.

McCuaig RD, Dunn J, Li J, Masch A, Knaute T, Schutkowski M, Zerweck J, Rao S.

Front Immunol. 2015 Nov 5;6:562. doi: 10.3389/fimmu.2015.00562. eCollection 2015.


High-Throughput Microarray Incubations Using Multi-Well Chambers.

Zerweck J, Reimer U, Jansong J, Pawlowski N, Tersch C, Eckey M, Knaute T.

Methods Mol Biol. 2016;1352:19-26. doi: 10.1007/978-1-4939-3037-1_2.


Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa.

Strandberg E, Zerweck J, Horn D, Pritz G, Berditsch M, Bürck J, Wadhwani P, Ulrich AS.

J Pept Sci. 2015 May;21(5):436-45. doi: 10.1002/psc.2780. Epub 2015 Apr 22.


Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development.

Stephenson KE, Neubauer GH, Reimer U, Pawlowski N, Knaute T, Zerweck J, Korber BT, Barouch DH.

J Immunol Methods. 2015 Jan;416:105-23. doi: 10.1016/j.jim.2014.11.006. Epub 2014 Nov 15.


Peptide microarrays enable rapid mimotope optimization for pharmacokinetic analysis of the novel therapeutic antibody IMAB362.

Schnatbaum K, Schmoldt HU, Daneschdar M, Plum LM, Jansong J, Zerweck J, Kühne Y, Masch A, Wenschuh H, Fiedler M, Türeci Ö, Sahin U, Reimer U.

Biotechnol J. 2014 Apr;9(4):545-54. doi: 10.1002/biot.201300456. Epub 2014 Mar 7.


Serotyping of Toxoplasma gondii in cats (Felis domesticus) reveals predominance of type II infections in Germany.

Maksimov P, Zerweck J, Dubey JP, Pantchev N, Frey CF, Maksimov A, Reimer U, Schutkowski M, Hosseininejad M, Ziller M, Conraths FJ, Schares G.

PLoS One. 2013 Nov 7;8(11):e80213. doi: 10.1371/journal.pone.0080213. eCollection 2013.


Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.

Gottardo R, Bailer RT, Korber BT, Gnanakaran S, Phillips J, Shen X, Tomaras GD, Turk E, Imholte G, Eckler L, Wenschuh H, Zerweck J, Greene K, Gao H, Berman PW, Francis D, Sinangil F, Lee C, Nitayaphan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Tartaglia J, Robb ML, Michael NL, Kim JH, Zolla-Pazner S, Haynes BF, Mascola JR, Self S, Gilbert P, Montefiori DC.

PLoS One. 2013 Sep 26;8(9):e75665. doi: 10.1371/journal.pone.0075665. eCollection 2013.


An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms.

Rauh D, Fischer F, Gertz M, Lakshminarasimhan M, Bergbrede T, Aladini F, Kambach C, Becker CF, Zerweck J, Schutkowski M, Steegborn C.

Nat Commun. 2013;4:2327. doi: 10.1038/ncomms3327.


Targeted identification of SUMOylation sites in human proteins using affinity enrichment and paralog-specific reporter ions.

Lamoliatte F, Bonneil E, Durette C, Caron-Lizotte O, Wildemann D, Zerweck J, Wenshuk H, Thibault P.

Mol Cell Proteomics. 2013 Sep;12(9):2536-50. doi: 10.1074/mcp.M112.025569. Epub 2013 Jun 7.


Synergistic insertion of antimicrobial magainin-family peptides in membranes depends on the lipid spontaneous curvature.

Strandberg E, Zerweck J, Wadhwani P, Ulrich AS.

Biophys J. 2013 Mar 19;104(6):L9-11. doi: 10.1016/j.bpj.2013.01.047. Epub 2013 Mar 19.


Peptide binding by catalytic domains of the protein disulfide isomerase-related protein ERp46.

Funkner A, Parthier C, Schutkowski M, Zerweck J, Lilie H, Gyrych N, Fischer G, Stubbs MT, Ferrari DM.

J Mol Biol. 2013 Apr 26;425(8):1340-62. doi: 10.1016/j.jmb.2013.01.029. Epub 2013 Jan 30.


Peptide microarray analysis of in silico-predicted epitopes for serological diagnosis of Toxoplasma gondii infection in humans.

Maksimov P, Zerweck J, Maksimov A, Hotop A, Gross U, Pleyer U, Spekker K, Däubener W, Werdermann S, Niederstrasser O, Petri E, Mertens M, Ulrich RG, Conraths FJ, Schares G.

Clin Vaccine Immunol. 2012 Jun;19(6):865-74. doi: 10.1128/CVI.00119-12. Epub 2012 Apr 11.


Analysis of clonal type-specific antibody reactions in Toxoplasma gondii seropositive humans from Germany by peptide-microarray.

Maksimov P, Zerweck J, Maksimov A, Hotop A, Gross U, Spekker K, Däubener W, Werdermann S, Niederstrasser O, Petri E, Mertens M, Ulrich RG, Conraths FJ, Schares G.

PLoS One. 2012;7(3):e34212. doi: 10.1371/journal.pone.0034212. Epub 2012 Mar 28.


Parvulin 17 promotes microtubule assembly by its peptidyl-prolyl cis/trans isomerase activity.

Thiele A, Krentzlin K, Erdmann F, Rauh D, Hause G, Zerweck J, Kilka S, Pösel S, Fischer G, Schutkowski M, Weiwad M.

J Mol Biol. 2011 Aug 26;411(4):896-909. doi: 10.1016/j.jmb.2011.06.040. Epub 2011 Jun 25.


The protein interaction network mediated by human SH3 domains.

Carducci M, Perfetto L, Briganti L, Paoluzi S, Costa S, Zerweck J, Schutkowski M, Castagnoli L, Cesareni G.

Biotechnol Adv. 2012 Jan-Feb;30(1):4-15. doi: 10.1016/j.biotechadv.2011.06.012. Epub 2011 Jun 29.


Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.

Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S.

J Biol Chem. 2011 Feb 18;286(7):5494-505. doi: 10.1074/jbc.M110.157909. Epub 2010 Dec 2.


High density peptide microarrays for proteome-wide fingerprinting of kinase activities in cell lysates.

Thiele A, Weiwad M, Zerweck J, Fischer G, Schutkowski M.

Methods Mol Biol. 2010;669:173-81. doi: 10.1007/978-1-60761-845-4_14.


Antibody signatures defined by high-content peptide microarray analysis.

Masch A, Zerweck J, Reimer U, Wenschuh H, Schutkowski M.

Methods Mol Biol. 2010;669:161-72. doi: 10.1007/978-1-60761-845-4_13.


High-density peptide microarrays for reliable identification of phosphorylation sites and upstream kinases.

Thiele A, Zerweck J, Weiwad M, Fischer G, Schutkowski M.

Methods Mol Biol. 2009;570:203-19. doi: 10.1007/978-1-60327-394-7_9. Review.


Peptide arrays for enzyme profiling.

Thiele A, Zerweck J, Schutkowski M.

Methods Mol Biol. 2009;570:19-65. doi: 10.1007/978-1-60327-394-7_2. Review.


Probing the epitope signatures of IgG antibodies in human serum from patients with autoimmune disease.

Lorenz P, Kreutzer M, Zerweck J, Schutkowski M, Thiesen HJ.

Methods Mol Biol. 2009;524:247-58. doi: 10.1007/978-1-59745-450-6_18.


Peptide microarrays for profiling of modification state-specific antibodies.

Zerweck J, Masch A, Schutkowski M.

Methods Mol Biol. 2009;524:169-80. doi: 10.1007/978-1-59745-450-6_12.


Major histocompatibility complex class II molecule-human immunodeficiency virus peptide analysis using a microarray chip.

Gaseitsiwe S, Valentini D, Ahmed R, Mahdavifar S, Magalhaes I, Zerweck J, Schutkowski M, Gautherot E, Montero F, Ehrnst A, Reilly M, Maeurer M.

Clin Vaccine Immunol. 2009 Apr;16(4):567-73. doi: 10.1128/CVI.00441-08. Epub 2009 Feb 18.


Pattern recognition in pulmonary tuberculosis defined by high content peptide microarray chip analysis representing 61 proteins from M. tuberculosis.

Gaseitsiwe S, Valentini D, Mahdavifar S, Magalhaes I, Hoft DF, Zerweck J, Schutkowski M, Andersson J, Reilly M, Maeurer MJ.

PLoS One. 2008;3(12):e3840. doi: 10.1371/journal.pone.0003840. Epub 2008 Dec 9.


Validation of peptide epitope microarray experiments and extraction of quality data.

Nahtman T, Jernberg A, Mahdavifar S, Zerweck J, Schutkowski M, Maeurer M, Reilly M.

J Immunol Methods. 2007 Dec 1;328(1-2):1-13. Epub 2007 Aug 13.


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