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Items: 1 to 50 of 143

1.

Neutrophils promote atherosclerotic plaque destabilization in a mouse model of endotoxinaemia.

Cochain C, Ait-Oufella H, Zernecke A.

Cardiovasc Res. 2018 Oct 1;114(12):1573-1574. doi: 10.1093/cvr/cvy168. No abstract available.

PMID:
29992257
2.

LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.

Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E.

Oncogene. 2018 Sep;37(36):4921-4940. doi: 10.1038/s41388-018-0320-2. Epub 2018 May 21.

3.

Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice.

Gotru SK, Gil-Pulido J, Beyersdorf N, Diefenbach A, Becker IC, Vögtle T, Remer K, Chubanov V, Gudermann T, Hermanns HM, Nieswandt B, Kerkau T, Zernecke A, Braun A.

J Immunol. 2018 Apr 15;200(8):2529-2534. doi: 10.4049/jimmunol.1701467. Epub 2018 Mar 26.

PMID:
29581357
4.

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.

PMID:
29545366
5.

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis.

Cochain C, Vafadarnejad E, Arampatzi P, Pelisek J, Winkels H, Ley K, Wolf D, Saliba AE, Zernecke A.

Circ Res. 2018 Jun 8;122(12):1661-1674. doi: 10.1161/CIRCRESAHA.117.312509. Epub 2018 Mar 15.

PMID:
29545365
6.

Extracellular Matrix Metalloproteinase Inducer EMMPRIN (CD147) in Cardiovascular Disease.

von Ungern-Sternberg SNI, Zernecke A, Seizer P.

Int J Mol Sci. 2018 Feb 8;19(2). pii: E507. doi: 10.3390/ijms19020507. Review.

7.

Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle.

Esser K, Lucifora J, Wettengel J, Singethan K, Glinzer A, Zernecke A, Protzer U.

Antiviral Res. 2018 Mar;151:4-7. doi: 10.1016/j.antiviral.2018.01.001. Epub 2018 Jan 5.

PMID:
29309795
8.

Using the Sleeve Technique in a Mouse Model of Aortic Transplantation - An Instructional Video.

Rowinska Z, Gorressen S, Merx MW, Koeppel TA, Zernecke A, Liehn EA.

J Vis Exp. 2017 Oct 22;(128). doi: 10.3791/54915.

9.

Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.

von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P.

Thromb Haemost. 2017 Nov;117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30.

10.

Cell differentiation defines acute and chronic infection cell types in Staphylococcus aureus.

García-Betancur JC, Goñi-Moreno A, Horger T, Schott M, Sharan M, Eikmeier J, Wohlmuth B, Zernecke A, Ohlsen K, Kuttler C, Lopez D.

Elife. 2017 Sep 12;6. pii: e28023. doi: 10.7554/eLife.28023.

11.

Antigen-presenting dendritic cells in atherosclerosis.

Gil-Pulido J, Zernecke A.

Eur J Pharmacol. 2017 Dec 5;816:25-31. doi: 10.1016/j.ejphar.2017.08.016. Epub 2017 Aug 16. Review.

PMID:
28822856
12.

Hypercholesterolemia induced cerebral small vessel disease.

Kraft P, Schuhmann MK, Garz C, Jandke S, Urlaub D, Mencl S, Zernecke A, Heinze HJ, Carare RO, Kleinschnitz C, Schreiber S.

PLoS One. 2017 Aug 10;12(8):e0182822. doi: 10.1371/journal.pone.0182822. eCollection 2017.

13.

Deletion of Batf3-dependent antigen-presenting cells does not affect atherosclerotic lesion formation in mice.

Gil-Pulido J, Cochain C, Lippert MA, Schneider N, Butt E, Amézaga N, Zernecke A.

PLoS One. 2017 Aug 3;12(8):e0181947. doi: 10.1371/journal.pone.0181947. eCollection 2017.

14.

Visualization of endothelial barrier damage prior to formation of atherosclerotic plaques.

Bömmel H, Kleefeldt F, Zernecke A, Ghavampour S, Wagner N, Kuerten S, Ergün S.

Histochem Cell Biol. 2017 Aug;148(2):117-127. doi: 10.1007/s00418-017-1562-8. Epub 2017 Mar 25.

PMID:
28343238
15.

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation.

Rowinska Z, Koeppel TA, Sanati M, Schelzig H, Jankowski J, Weber C, Zernecke A, Liehn EA.

PLoS One. 2017 Feb 24;12(2):e0170644. doi: 10.1371/journal.pone.0170644. eCollection 2017.

16.

Macrophages in vascular inflammation and atherosclerosis.

Cochain C, Zernecke A.

Pflugers Arch. 2017 Apr;469(3-4):485-499. doi: 10.1007/s00424-017-1941-y. Epub 2017 Feb 6. Review.

PMID:
28168325
17.

Targeting Elastase for Molecular Imaging of Early Atherosclerotic Lesions.

Glinzer A, Ma X, Prakash J, Kimm MA, Lohöfer F, Kosanke K, Pelisek J, Thon MP, Vorlova S, Heinze KG, Eckstein HH, Gee MW, Ntziachristos V, Zernecke A, Wildgruber M.

Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):525-533. doi: 10.1161/ATVBAHA.116.308726. Epub 2016 Dec 29.

PMID:
28062502
18.

The "Intermediate" CD14++CD16+ monocyte subset increases in severe peripheral artery disease in humans.

Wildgruber M, Aschenbrenner T, Wendorff H, Czubba M, Glinzer A, Haller B, Schiemann M, Zimmermann A, Berger H, Eckstein HH, Meier R, Wohlgemuth WA, Libby P, Zernecke A.

Sci Rep. 2016 Dec 19;6:39483. doi: 10.1038/srep39483.

19.

CD98 promotes vascular smooth muscle cell accumulation in atherosclerosis to confer plaque stability.

Zernecke A.

Atherosclerosis. 2017 Jan;256:128-130. doi: 10.1016/j.atherosclerosis.2016.11.028. Epub 2016 Nov 27. No abstract available.

PMID:
27939649
20.

Congenital valvular defects associated with deleterious mutations in the PLD1 gene.

Ta-Shma A, Zhang K, Salimova E, Zernecke A, Sieiro-Mosti D, Stegner D, Furtado M, Shaag A, Perles Z, Nieswandt B, Rein AJ, Rosenthal N, Neiman AM, Elpeleg O.

J Med Genet. 2017 Apr;54(4):278-286. doi: 10.1136/jmedgenet-2016-104259. Epub 2016 Oct 31.

PMID:
27799408
21.

Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice.

Vorlova S, Koch M, Manthey HD, Cochain C, Busch M, Chaudhari SM, Stegner D, Yepes M, Lorenz K, Nolte MW, Nieswandt B, Zernecke A.

Thromb Haemost. 2017 Jan 5;117(1):176-187. doi: 10.1160/TH16-06-0466. Epub 2016 Oct 27.

PMID:
27786338
22.

Protective and pathogenic roles of CD8+ T cells in atherosclerosis.

Cochain C, Zernecke A.

Basic Res Cardiol. 2016 Nov;111(6):71. Epub 2016 Oct 25. Review.

PMID:
27783202
23.

Increased intermediate CD14++CD16++ monocyte subset levels associate with restenosis after peripheral percutaneous transluminal angioplasty.

Wildgruber M, Czubba M, Aschenbrenner T, Wendorff H, Hapfelmeier A, Glinzer A, Schiemann M, Zimmermann A, Eckstein HH, Berger H, Wohlgemuth WA, Meier R, Libby P, Zernecke A.

Atherosclerosis. 2016 Oct;253:128-134. doi: 10.1016/j.atherosclerosis.2016.09.002. Epub 2016 Sep 2.

PMID:
27615596
24.

Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1).

Endres M, Kneitz S, Orth MF, Perera RK, Zernecke A, Butt E.

Oncotarget. 2016 Sep 27;7(39):64244-64259. doi: 10.18632/oncotarget.11720.

25.

Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice.

Simsekyilmaz S, Liehn EA, Weinandy S, Schreiber F, Megens RT, Theelen W, Smeets R, Jockenhövel S, Gries T, Möller M, Klee D, Weber C, Zernecke A.

PLoS One. 2016 May 18;11(5):e0155829. doi: 10.1371/journal.pone.0155829. eCollection 2016.

26.

Extracellular Ribonucleic Acids (RNA) Enter the Stage in Cardiovascular Disease.

Zernecke A, Preissner KT.

Circ Res. 2016 Feb 5;118(3):469-79. doi: 10.1161/CIRCRESAHA.115.307961. Review.

PMID:
26846641
27.

Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology.

Busch A, Busch M, Scholz CJ, Kellersmann R, Otto C, Chernogubova E, Maegdefessel L, Zernecke A, Lorenz U.

Int J Mol Sci. 2016 Jan 12;17(1). pii: E81. doi: 10.3390/ijms17010081.

28.

Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm.

Han Y, Tanios F, Reeps C, Zhang J, Schwamborn K, Eckstein HH, Zernecke A, Pelisek J.

Clin Epigenetics. 2016 Jan 13;8:3. doi: 10.1186/s13148-016-0169-6. eCollection 2016.

29.

Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques.

Greißel A, Culmes M, Burgkart R, Zimmermann A, Eckstein HH, Zernecke A, Pelisek J.

Cardiovasc Pathol. 2016 Mar-Apr;25(2):79-86. doi: 10.1016/j.carpath.2015.11.001. Epub 2015 Nov 9.

PMID:
26764138
30.

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke.

Kraft P, Schuhmann MK, Fluri F, Lorenz K, Zernecke A, Stoll G, Nieswandt B, Kleinschnitz C.

Stroke. 2015 Dec;46(12):3502-6. doi: 10.1161/STROKEAHA.115.011114. Epub 2015 Oct 20.

PMID:
26486866
31.

Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms.

Wendorff C, Wendorff H, Pelisek J, Tsantilas P, Zimmermann A, Zernecke A, Kuehnl A, Eckstein HH.

Stroke. 2015 Nov;46(11):3213-9. doi: 10.1161/STROKEAHA.115.010558. Epub 2015 Oct 8.

PMID:
26451032
32.

Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.

Chaudhari SM, Sluimer JC, Koch M, Theelen TL, Manthey HD, Busch M, Caballero-Franco C, Vogel F, Cochain C, Pelisek J, Daemen MJ, Lutz MB, Görlach A, Kissler S, Hermanns HM, Zernecke A.

Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2316-25. doi: 10.1161/ATVBAHA.115.306171. Epub 2015 Sep 24.

33.

Stimulating arteriogenesis but not atherosclerosis: IFN-α/β receptor subunit 1 as a novel therapeutic target.

Cochain C, Zernecke A.

Cardiovasc Res. 2015 Jul 15;107(2):200-2. doi: 10.1093/cvr/cvv174. Epub 2015 Jun 17. No abstract available.

PMID:
26084309
34.

Alternation of histone and DNA methylation in human atherosclerotic carotid plaques.

Greißel A, Culmes M, Napieralski R, Wagner E, Gebhard H, Schmitt M, Zimmermann A, Eckstein HH, Zernecke A, Pelisek J.

Thromb Haemost. 2015 Aug;114(2):390-402. doi: 10.1160/TH14-10-0852. Epub 2015 May 21.

PMID:
25993995
35.

CD8+ T Cells Regulate Monopoiesis and Circulating Ly6C-high Monocyte Levels in Atherosclerosis in Mice.

Cochain C, Koch M, Chaudhari SM, Busch M, Pelisek J, Boon L, Zernecke A.

Circ Res. 2015 Jul 17;117(3):244-53. doi: 10.1161/CIRCRESAHA.117.304611. Epub 2015 May 19.

PMID:
25991812
36.

Macrophages and immune cells in atherosclerosis: recent advances and novel concepts.

Cochain C, Zernecke A.

Basic Res Cardiol. 2015;110(4):34. doi: 10.1007/s00395-015-0491-8. Epub 2015 May 7. Review.

PMID:
25947006
37.

Dendritic cells in atherosclerosis: evidence in mice and humans.

Zernecke A.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):763-70. doi: 10.1161/ATVBAHA.114.303566. Epub 2015 Feb 12. Review.

PMID:
25675999
38.

Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study.

Kornmann LM, Zernecke A, Curfs DM, Janssen BJ, Weber C, de Winther MP, Reneman RS, Hoeks AP, Reesink KD.

Cardiovasc Ultrasound. 2015 Jan 8;13:1. doi: 10.1186/1476-7120-13-1.

39.

The hemostatic system as a regulator of inflammation in atherosclerosis.

Koch M, Zernecke A.

IUBMB Life. 2014 Nov;66(11):735-44. doi: 10.1002/iub.1333. Epub 2014 Dec 9. Review.

40.

STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic responses in human atherosclerosis.

Chmielewski S, Olejnik A, Sikorski K, Pelisek J, Błaszczyk K, Aoqui C, Nowicka H, Zernecke A, Heemann U, Wesoly J, Baumann M, Bluyssen HA.

PLoS One. 2014 Dec 5;9(12):e113318. doi: 10.1371/journal.pone.0113318. eCollection 2014.

41.

Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice".

Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A.

Circulation. 2014 Oct 14;130(16):e144-5. doi: 10.1161/CIRCULATIONAHA.114.012346. No abstract available.

PMID:
25311624
42.

Establishment of a new murine elastase-induced aneurysm model combined with transplantation.

Rowinska Z, Gorressen S, Merx MW, Koeppel TA, Liehn EA, Zernecke A.

PLoS One. 2014 Jul 28;9(7):e102648. doi: 10.1371/journal.pone.0102648. eCollection 2014.

43.

Noncoding RNAs in vascular inflammation and atherosclerosis: recent advances toward therapeutic applications.

Cochain C, Zernecke A.

Curr Opin Lipidol. 2014 Oct;25(5):380-6. doi: 10.1097/MOL.0000000000000108. Review.

PMID:
25051497
44.

Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms.

Lohoefer F, Reeps C, Lipp C, Rudelius M, Haertl F, Matevossian E, Zernecke A, Eckstein HH, Pelisek J.

Exp Mol Med. 2014 May 16;46:e95. doi: 10.1038/emm.2014.20.

45.

Distinct functions of specialized dendritic cell subsets in atherosclerosis and the road ahead.

Zernecke A.

Scientifica (Cairo). 2014;2014:952625. doi: 10.1155/2014/952625. Epub 2014 Apr 10. Review.

46.

CXCR4 blockade induces atherosclerosis by affecting neutrophil function.

Bot I, Daissormont IT, Zernecke A, van Puijvelde GH, Kramp B, de Jager SC, Sluimer JC, Manca M, Hérias V, Westra MM, Bot M, van Santbrink PJ, van Berkel TJ, Su L, Skjelland M, Gullestad L, Kuiper J, Halvorsen B, Aukrust P, Koenen RR, Weber C, Biessen EA.

J Mol Cell Cardiol. 2014 Sep;74:44-52. doi: 10.1016/j.yjmcc.2014.04.021. Epub 2014 May 8.

47.

Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice.

Cochain C, Chaudhari SM, Koch M, Wiendl H, Eckstein HH, Zernecke A.

PLoS One. 2014 Apr 1;9(4):e93280. doi: 10.1371/journal.pone.0093280. eCollection 2014.

48.

Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice.

Busch M, Westhofen TC, Koch M, Lutz MB, Zernecke A.

PLoS One. 2014 Feb 14;9(2):e88452. doi: 10.1371/journal.pone.0088452. eCollection 2014.

49.

Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.

Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp BK, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng TM, Groll J, Weber C, Liehn EA, Koenen RR.

J Cell Mol Med. 2014 May;18(5):790-800. doi: 10.1111/jcmm.12225. Epub 2014 Feb 6.

50.

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.

Tilstam PV, Gijbels MJ, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Döring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen RR, de Winther MP, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H.

PLoS One. 2014 Feb 3;9(2):e87452. doi: 10.1371/journal.pone.0087452. eCollection 2014.

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