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Impact of nutrition route on microaspiration in critically ill patients with shock: a planned ancillary study of the NUTRIREA-2 trial.

Nseir S, Le Gouge A, Lascarrou JB, Lacherade JC, Jaillette E, Mira JP, Mercier E, Declercq PL, Sirodot M, Piton G, Tinturier F, Coupez E, Gaudry S, Djibré M, Thevenin D, Pasco J, Balduyck M, Zerimech F, Reignier J.

Crit Care. 2019 Apr 5;23(1):111. doi: 10.1186/s13054-019-2403-z.


Analysis of Mucopolysaccharidosis Type VI through Integrative Functional Metabolomics.

Tebani A, Abily-Donval L, Schmitz-Afonso I, Piraud M, Ausseil J, Zerimech F, Pilon C, Pereira T, Marret S, Afonso C, Bekri S.

Int J Mol Sci. 2019 Jan 21;20(2). pii: E446. doi: 10.3390/ijms20020446.


Impact of subglottic secretion drainage on microaspiration in critically ill patients: a prospective observational study.

Millot G, Boddaert P, Parmentier-Decrucq E, Palud A, Balduyck M, Maboudou P, Zerimech F, Wallet F, Preau S, Nseir S.

Ann Transl Med. 2018 Nov;6(21):416. doi: 10.21037/atm.2018.10.44.


Description of 22 new alpha-1 antitrypsin genetic variants.

Renoux C, Odou MF, Tosato G, Teoli J, Abbou N, Lombard C, Zerimech F, Porchet N, Chapuis Cellier C, Balduyck M, Joly P.

Orphanet J Rare Dis. 2018 Sep 17;13(1):161. doi: 10.1186/s13023-018-0897-0.


Unveiling metabolic remodeling in mucopolysaccharidosis type III through integrative metabolomics and pathway analysis.

Tebani A, Abily-Donval L, Schmitz-Afonso I, Héron B, Piraud M, Ausseil J, Zerimech F, Gonzalez B, Marret S, Afonso C, Bekri S.

J Transl Med. 2018 Sep 4;16(1):248. doi: 10.1186/s12967-018-1625-1.


Alpha1 antitrypsin deficiency due to an homozygous PI* Null Q0Cairo mutation: Early onset of pulmonary manifestations and variability of clinical expression.

Jouhadi Z, Odou MF, Zerimech F, Bousfiha AA, Mikou N, Porchet N, Crepin M, Najib J, Balduyck M.

Respir Med Case Rep. 2018 Apr 10;24:58-62. doi: 10.1016/j.rmcr.2018.04.005. eCollection 2018.


Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study.

Havet A, Zerimech F, Sanchez M, Siroux V, Le Moual N, Brunekreef B, Stempfelet M, Künzli N, Jacquemin B, Matran R, Nadif R.

Eur Respir J. 2018 Apr 4;51(4). pii: 1702036. doi: 10.1183/13993003.02036-2017. Print 2018 Apr.


Oxidative stress biomarkers and asthma characteristics in adults of the EGEA study.

Andrianjafimasy M, Zerimech F, Akiki Z, Huyvaert H, Le Moual N, Siroux V, Matran R, Dumas O, Nadif R.

Eur Respir J. 2017 Dec 28;50(6). pii: 1701193. doi: 10.1183/13993003.01193-2017. Print 2017 Dec.


Relationship between hyperoxemia and ventilator associated pneumonia.

Jaffal K, Six S, Zerimech F, Nseir S.

Ann Transl Med. 2017 Nov;5(22):453. doi: 10.21037/atm.2017.10.15. Review.


Urinary metabolic phenotyping of mucopolysaccharidosis type I combining untargeted and targeted strategies with data modeling.

Tebani A, Schmitz-Afonso I, Abily-Donval L, Héron B, Piraud M, Ausseil J, Brassier A, De Lonlay P, Zerimech F, Vaz FM, Gonzalez BJ, Marret S, Afonso C, Bekri S.

Clin Chim Acta. 2017 Dec;475:7-14. doi: 10.1016/j.cca.2017.09.024. Epub 2017 Oct 2.


Is hyperoxaemia a risk factor for ICU-acquired pneumonia?

Jaffal K, Six S, Zerimech F, Nseir S.

Lancet Respir Med. 2017 May;5(5):e16. doi: 10.1016/S2213-2600(17)30121-2. Epub 2017 Apr 24. No abstract available.


Impact of tapered-cuff tracheal tube on microaspiration of gastric contents in intubated critically ill patients: a multicenter cluster-randomized cross-over controlled trial.

Jaillette E, Girault C, Brunin G, Zerimech F, Behal H, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Labreuche J, Robriquet L, Tamion F, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S; BestCuff Study Group and the BoRéal Network.

Intensive Care Med. 2017 Nov;43(11):1562-1571. doi: 10.1007/s00134-017-4736-x. Epub 2017 Mar 16.


Efficiency of an electronic device in controlling tracheal cuff pressure in critically ill patients: a randomized controlled crossover study.

Rouzé A, De Jonckheere J, Zerimech F, Labreuche J, Parmentier-Decrucq E, Voisin B, Jaillette E, Maboudou P, Balduyck M, Nseir S.

Ann Intensive Care. 2016 Dec;6(1):93. doi: 10.1186/s13613-016-0200-2. Epub 2016 Oct 4.


Lack of Relationship Between Clinical Features and KRAS Mutations in Patients with Metastatic Colorectal Cancer.

Ploquin A, Zerimech F, Escande F, Adenis A, Giraud C, Gasnault L, Bourgeois V, Desauw C, Hebbar M.

Anticancer Res. 2016 Aug;36(8):4233-6.


Tapered-cuff Endotracheal Tube Does Not Prevent Early Postoperative Pneumonia Compared with Spherical-cuff Endotracheal Tube after Major Vascular Surgery: A Randomized Controlled Trial.

Monsel A, Lu Q, Le Corre M, Brisson H, Arbelot C, Vezinet C, Fléron MH, Ibanez-Estève C, Zerimech F, Balduyck M, Dexheimer F, Wang C, Langeron O, Rouby JJ, Bodin L, Deransy R, Garçon P, Douiri H, Khalifa I, Pons A, Gu WJ, Koskas F, Gaudric J; TETRIS Study Group.

Anesthesiology. 2016 May;124(5):1041-52. doi: 10.1097/ALN.0000000000001053.


Impact of tracheal cuff shape on microaspiration of gastric contents in intubated critically ill patients: study protocol for a randomized controlled trial.

Jaillette E, Brunin G, Girault C, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Tamion F, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S.

Trials. 2015 Sep 25;16:429. doi: 10.1186/s13063-015-0955-z.


Occupational exposures and fluorescent oxidation products in 723 adults of the EGEA study.

Dumas O, Matran R, Zerimech F, Decoster B, Huyvaert H, Ahmed I, Le Moual N, Nadif R.

Eur Respir J. 2015 Jul;46(1):258-61. doi: 10.1183/09031936.00177614. Epub 2015 Apr 2. No abstract available.


[Development of a laboratory test on dried blood spots for facilitating early diagnosis of alpha-1-antitrypsin deficiency].

Balduyck M, Chapuis Cellier C, Roche D, Odou MF, Joly P, Madelain V, Vergne A, Nouadje G, Lafitte JJ, Porchet N, Beaune P, Zerimech F.

Ann Biol Clin (Paris). 2014 Nov-Dec;72(6):689-704. doi: 10.1684/abc.2014.1004. French.


Diagnosis of alpha-1 antitrypsin deficiency: modalities, indications and diagnosis strategy.

Balduyck M, Odou MF, Zerimech F, Porchet N, Lafitte JJ, Maitre B.

Rev Mal Respir. 2014 Oct;31(8):729-45. doi: 10.1016/j.rmr.2014.06.001. Epub 2014 Jul 3. Review.


Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients.

Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B.

Circulation. 2014 Aug 12;130(7):554-64. doi: 10.1161/CIRCULATIONAHA.113.008476. Epub 2014 Jun 13.


Exhaled nitric oxide, nitrite/nitrate levels, allergy, rhinitis and asthma in the EGEA study.

Nadif R, Rava M, Decoster B, Huyvaert H, Le Moual N, Bousquet J, Siroux V, Varraso R, Pin I, Zerimech F, Matran R.

Eur Respir J. 2014 Aug;44(2):351-60. doi: 10.1183/09031936.00202413. Epub 2014 May 2.


Accuracy of alpha amylase in diagnosing microaspiration in intubated critically-ill patients.

Dewavrin F, Zerimech F, Boyer A, Maboudou P, Balduyck M, Duhamel A, Nseir S.

PLoS One. 2014 Mar 6;9(6):e90851. doi: 10.1371/journal.pone.0090851. eCollection 2014.


TP53 mutations in colorectal cancer from Tunisia: relationships with site of tumor origin, microsatellite instability and KRAS mutations.

Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N.

Mol Biol Rep. 2014 Mar;41(3):1807-13. doi: 10.1007/s11033-014-3030-z. Epub 2014 Jan 18.


Efficiency of a pneumatic device in controlling cuff pressure of polyurethane-cuffed tracheal tubes: a randomized controlled study.

Jaillette E, Zerimech F, De Jonckheere J, Makris D, Balduyck M, Durocher A, Duhamel A, Nseir S.

BMC Anesthesiol. 2013 Dec 26;13(1):50. doi: 10.1186/1471-2253-13-50.


KRAS mutations in colorectal cancer from Tunisia: relationships with clinicopathologic variables and data on TP53 mutations and microsatellite instability.

Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N.

Mol Biol Rep. 2013 Nov;40(11):6107-12.


Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.

Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N.

World J Gastroenterol. 2013 Aug 28;19(32):5286-94. doi: 10.3748/wjg.v19.i32.5286.


The role of eosinophils and basophils in allergic diseases considering genetic findings.

Nadif R, Zerimech F, Bouzigon E, Matran R.

Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):507-13. doi: 10.1097/ACI.0b013e328364e9c0. Review.


Evaluation of a new panel of six mononucleotide repeat markers for the detection of DNA mismatch repair-deficient tumours.

Pagin A, Zerimech F, Leclerc J, Wacrenier A, Lejeune S, Descarpentries C, Escande F, Porchet N, Buisine MP.

Br J Cancer. 2013 May 28;108(10):2079-87. doi: 10.1038/bjc.2013.213. Epub 2013 May 7.


Mitochondrial dysfunction as an arrhythmogenic substrate: a translational proof-of-concept study in patients with metabolic syndrome in whom post-operative atrial fibrillation develops.

Montaigne D, Marechal X, Lefebvre P, Modine T, Fayad G, Dehondt H, Hurt C, Coisne A, Koussa M, Remy-Jouet I, Zerimech F, Boulanger E, Lacroix D, Staels B, Neviere R.

J Am Coll Cardiol. 2013 Oct 15;62(16):1466-73. doi: 10.1016/j.jacc.2013.03.061. Epub 2013 May 1.


Plasma and exhaled breath condensate nitrite-nitrate level in relation to environmental exposures in adults in the EGEA study.

Rava M, Varraso R, Decoster B, Huyvaert H, Le Moual N, Jacquemin B, Künzli N, Kauffmann F, Zerimech F, Matran R, Nadif R.

Nitric Oxide. 2012 Oct 15;27(3):169-75. doi: 10.1016/j.niox.2012.06.007. Epub 2012 Jun 27.


Continuous control of tracheal cuff pressure and microaspiration of gastric contents in critically ill patients.

Nseir S, Zerimech F, Fournier C, Lubret R, Ramon P, Durocher A, Balduyck M.

Am J Respir Crit Care Med. 2011 Nov 1;184(9):1041-7. doi: 10.1164/rccm.201104-0630OC.


Microaspiration in intubated critically ill patients: diagnosis and prevention.

Nseir S, Zerimech F, Jaillette E, Artru F, Balduyck M.

Infect Disord Drug Targets. 2011 Aug;11(4):413-23. Review.


Usefulness of a new dialysis device adapted to small volume of red blood cells and its interest in epidemiology.

Zerimech F, Huyvaert H, Matran R, Nadif R.

Clin Biochem. 2011 Jun;44(8-9):739-41. doi: 10.1016/j.clinbiochem.2011.03.023. Epub 2011 Mar 21.


Lynch syndrome in Tunisia: first description of clinical features and germline mutations.

Moussa SA, Moussa A, Kourda N, Mezlini A, Abdelli N, Zerimech F, Najjar T, Jilani SB, Porchet N, Ayed FB, Manai M, Buisine MP.

Int J Colorectal Dis. 2011 Apr;26(4):455-67. doi: 10.1007/s00384-010-1129-9. Epub 2011 Feb 11.


Impact of polyurethane on variations in tracheal cuff pressure in critically ill patients: a prospective observational study.

Nseir S, Zerimech F, De Jonckheere J, Alves I, Balduyck M, Durocher A.

Intensive Care Med. 2010 Jul;36(7):1156-63. doi: 10.1007/s00134-010-1892-7. Epub 2010 Apr 16.


Serum mesothelin has a higher diagnostic utility than hyaluronic acid in malignant mesothelioma.

Grigoriu B, Chahine B, Zerimech F, Grégoire M, Balduyck M, Copin MC, Devos P, Lassalle P, Scherpereel A.

Clin Biochem. 2009 Jul;42(10-11):1046-50. doi: 10.1016/j.clinbiochem.2009.03.007. Epub 2009 Mar 18.


Antibodies against glucan, chitin, and Saccharomyces cerevisiae mannan as new biomarkers of Candida albicans infection that complement tests based on C. albicans mannan.

Sendid B, Dotan N, Nseir S, Savaux C, Vandewalle P, Standaert A, Zerimech F, Guery BP, Dukler A, Colombel JF, Poulain D.

Clin Vaccine Immunol. 2008 Dec;15(12):1868-77. doi: 10.1128/CVI.00200-08. Epub 2008 Oct 29.


Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress.

Marechal X, Favory R, Joulin O, Montaigne D, Hassoun S, Decoster B, Zerimech F, Neviere R.

Shock. 2008 May;29(5):572-6. doi: 10.1097/SHK.0b013e318157e926.


E-cadherin and beta-catenin mRNA levels throughout colon cancer progression.

Truant SC, Gouyer VP, Leteurtre EA, Zerimech F, Huet GM, Pruvot FR.

J Surg Res. 2008 Dec;150(2):212-8. doi: 10.1016/j.jss.2007.12.800. Epub 2008 Feb 11.


Evaluation of a new Sebia isoelectrofocusing kit for alpha 1-antitrypsin phenotyping with the Hydrasys System.

Zerimech F, Hennache G, Bellon F, Barouh G, Jacques Lafitte J, Porchet N, Balduyck M.

Clin Chem Lab Med. 2008;46(2):260-3.


Cysteine and serine proteases of synovial tissue in rheumatoid arthritis and osteoarthritis.

Solau-Gervais E, Zerimech F, Lemaire R, Fontaine C, Huet G, Flipo RM.

Scand J Rheumatol. 2007 Sep-Oct;36(5):373-7.


Biomonitoring of the adverse effects induced by the chronic exposure to lead and cadmium on kidney function: usefulness of alpha-glutathione S-transferase.

Garçon G, Leleu B, Marez T, Zerimech F, Haguenoer JM, Furon D, Shirali P.

Sci Total Environ. 2007 May 15;377(2-3):165-72. Epub 2007 Mar 26.


Prospective evaluation of the new chromogenic medium CandiSelect 4 for differentiation and presumptive identification of the major pathogenic Candida species.

Sendid B, François N, Standaert A, Dehecq E, Zerimech F, Camus D, Poulain D.

J Med Microbiol. 2007 Apr;56(Pt 4):495-9.


Relationships between mucinous gastric carcinoma, MUC2 expression and survival.

Leteurtre E, Zerimech F, Piessen G, Wacrenier A, Leroy X, Copin MC, Mariette C, Aubert JP, Porchet N, Buisine MP.

World J Gastroenterol. 2006 Jun 7;12(21):3324-31.


Dunkerque City air pollution particulate matter-induced cytotoxicity, oxidative stress and inflammation in human epithelial lung cells (L132) in culture.

Garçon G, Dagher Z, Zerimech F, Ledoux F, Courcot D, Aboukais A, Puskaric E, Shirali P.

Toxicol In Vitro. 2006 Jun;20(4):519-28. Epub 2005 Nov 17.


Tissue inhibitor of metalloproteinase 1 is an independent predictor of prognosis in patients with nonsmall cell lung carcinoma who undergo resection with curative intent.

Gouyer V, Conti M, Devos P, Zerimech F, Copin MC, Créme E, Wurtz A, Porte H, Huet G.

Cancer. 2005 Apr 15;103(8):1676-84.


Biologic markers of oxidative stress and nephrotoxicity as studied in biomonitoring of adverse effects of occupational exposure to lead and cadmium.

Garçon G, Leleu B, Zerimech F, Marez T, Haguenoer JM, Furon D, Shirali P.

J Occup Environ Med. 2004 Nov;46(11):1180-6.


Influence of iron (56Fe2O3 or 54Fe2O3) in the upregulation of cytochrome P4501A1 by benzo[a]pyrene in the respiratory tract of Sprague-Dawley rats.

Garçon G, Gosset P, Maunit B, Zerimech F, Creusy C, Muller JF, Shirali P.

J Appl Toxicol. 2004 May-Jun;24(3):249-56.


Environmental lead exposure and its relationship to traffic density among Senegalese children: a pilot study.

Diouf A, Garçon G, Thiaw C, Diop Y, Fall M, Ndiaye B, Siby T, Hannothiaux MH, Zerimech F, Ba D, Haguenoer JM, Shirali P.

Hum Exp Toxicol. 2003 Oct;22(10):559-64.


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