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Items: 1 to 50 of 237

1.

The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.

Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W.

Nat Commun. 2016 Mar 7;7:10764. doi: 10.1038/ncomms10764.

2.

Overexpression of FXYD-3 is involved in the tumorigenesis and development of esophageal squamous cell carcinoma.

Zhu ZL, Yan BY, Zhang Y, Yang YH, Wang MW, Zentgraf H, Zhang XH, Sun XF.

Dis Markers. 2013;35(3):195-202. doi: 10.1155/2013/740201. Epub 2013 Aug 27.

3.

Up-regulation of two distinct p53-DNA binding functions by covalent poly(ADP-ribosyl)ation: transactivating and single strand break sensing.

Alvarez-Gonzalez R, Mendoza-Alvarez H, Frey M, Zentgraf H.

Cancer Invest. 2013 Nov;31(9):563-70. doi: 10.3109/07357907.2013.845670.

PMID:
24164297
4.

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Döhner H, Lichter P, Stilgenbauer S, Mertens D.

PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4.

5.

The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells.

Maier B, Kirsch M, Anderhub S, Zentgraf H, Krämer A.

Cell Cycle. 2013 May 1;12(9):1457-71. doi: 10.4161/cc.24602. Epub 2013 Apr 10.

6.

The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.

Kuhns S, Schmidt KN, Reymann J, Gilbert DF, Neuner A, Hub B, Carvalho R, Wiedemann P, Zentgraf H, Erfle H, Klingmüller U, Boutros M, Pereira G.

J Cell Biol. 2013 Feb 18;200(4):505-22. doi: 10.1083/jcb.201206013. Epub 2013 Feb 11.

7.

Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis.

Schmidt KN, Kuhns S, Neuner A, Hub B, Zentgraf H, Pereira G.

J Cell Biol. 2012 Dec 24;199(7):1083-101. doi: 10.1083/jcb.201202126. Epub 2012 Dec 17.

8.

Characterization and manipulation of foamy virus membrane interactions.

Swiersy A, Wiek C, Zentgraf H, Lindemann D.

Cell Microbiol. 2013 Feb;15(2):227-36. doi: 10.1111/cmi.12042. Epub 2012 Nov 6.

PMID:
23051660
9.

Different conformational forms of serum carnosinase detected by a newly developed sandwich ELISA for the measurements of carnosinase concentrations.

Adelmann K, Frey D, Riedl E, Koeppel H, Pfister F, Peters V, Schmitt CP, Sternik P, Hofmann S, Zentgraf HW, Navis G, van den Born J, Bakker SJ, Krämer BK, Yard BA, Hauske SJ.

Amino Acids. 2012 Jul;43(1):143-51. doi: 10.1007/s00726-012-1244-8. Epub 2012 Feb 17.

PMID:
22349764
10.

STIL is required for centriole duplication in human cells.

Vulprecht J, David A, Tibelius A, Castiel A, Konotop G, Liu F, Bestvater F, Raab MS, Zentgraf H, Izraeli S, Krämer A.

J Cell Sci. 2012 Mar 1;125(Pt 5):1353-62. doi: 10.1242/jcs.104109. Epub 2012 Feb 20.

11.

Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.

Rausch V, Liu L, Apel A, Rettig T, Gladkich J, Labsch S, Kallifatidis G, Kaczorowski A, Groth A, Gross W, Gebhard MM, Schemmer P, Werner J, Salnikov AV, Zentgraf H, Büchler MW, Herr I.

J Pathol. 2012 Jul;227(3):325-35. doi: 10.1002/path.3994. Epub 2012 Apr 18.

PMID:
22262369
12.

Orthoretroviral-like prototype foamy virus Gag-Pol expression is compatible with viral replication.

Swiersy A, Wiek C, Reh J, Zentgraf H, Lindemann D.

Retrovirology. 2011 Aug 15;8:66. doi: 10.1186/1742-4690-8-66.

13.

Molecular basis for the unique role of the AAA+ chaperone ClpV in type VI protein secretion.

Pietrosiuk A, Lenherr ED, Falk S, Bönemann G, Kopp J, Zentgraf H, Sinning I, Mogk A.

J Biol Chem. 2011 Aug 26;286(34):30010-21. doi: 10.1074/jbc.M111.253377. Epub 2011 Jul 5.

14.

An epichromatin epitope: persistence in the cell cycle and conservation in evolution.

Olins AL, Langhans M, Monestier M, Schlotterer A, Robinson DG, Viotti C, Zentgraf H, Zwerger M, Olins DE.

Nucleus. 2011 Jan-Feb;2(1):47-60. doi: 10.4161/nucl.1.6.13271.

15.

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody.

Capper D, Preusser M, Habel A, Sahm F, Ackermann U, Schindler G, Pusch S, Mechtersheimer G, Zentgraf H, von Deimling A.

Acta Neuropathol. 2011 Jul;122(1):11-9. doi: 10.1007/s00401-011-0841-z. Epub 2011 Jun 3.

PMID:
21638088
16.

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics.

Dafinger C, Liebau MC, Elsayed SM, Hellenbroich Y, Boltshauser E, Korenke GC, Fabretti F, Janecke AR, Ebermann I, Nürnberg G, Nürnberg P, Zentgraf H, Koerber F, Addicks K, Elsobky E, Benzing T, Schermer B, Bolz HJ.

J Clin Invest. 2011 Jul;121(7):2662-7. doi: 10.1172/JCI43639.

17.

Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer.

Naumann P, Fortunato F, Zentgraf H, Büchler MW, Herr I, Werner J.

Int J Oncol. 2011 Jul;39(1):101-9. doi: 10.3892/ijo.2011.1025. Epub 2011 Apr 29.

PMID:
21537844
18.

Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis.

Meitinger F, Boehm ME, Hofmann A, Hub B, Zentgraf H, Lehmann WD, Pereira G.

Genes Dev. 2011 Apr 15;25(8):875-88. doi: 10.1101/gad.622411.

19.

Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

Liebau MC, Höpker K, Müller RU, Schmedding I, Zank S, Schairer B, Fabretti F, Höhne M, Bartram MP, Dafinger C, Hackl M, Burst V, Habbig S, Zentgraf H, Blaukat A, Walz G, Benzing T, Schermer B.

J Biol Chem. 2011 Apr 22;286(16):14237-45. doi: 10.1074/jbc.M110.165464. Epub 2011 Feb 28.

20.

CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs.

Merveille AC, Davis EE, Becker-Heck A, Legendre M, Amirav I, Bataille G, Belmont J, Beydon N, Billen F, Clément A, Clercx C, Coste A, Crosbie R, de Blic J, Deleuze S, Duquesnoy P, Escalier D, Escudier E, Fliegauf M, Horvath J, Hill K, Jorissen M, Just J, Kispert A, Lathrop M, Loges NT, Marthin JK, Momozawa Y, Montantin G, Nielsen KG, Olbrich H, Papon JF, Rayet I, Roger G, Schmidts M, Tenreiro H, Towbin JA, Zelenika D, Zentgraf H, Georges M, Lequarré AS, Katsanis N, Omran H, Amselem S.

Nat Genet. 2011 Jan;43(1):72-8. doi: 10.1038/ng.726. Epub 2010 Dec 5.

21.

Novel functions of prototype foamy virus Gag glycine- arginine-rich boxes in reverse transcription and particle morphogenesis.

Müllers E, Uhlig T, Stirnnagel K, Fiebig U, Zentgraf H, Lindemann D.

J Virol. 2011 Feb;85(4):1452-63. doi: 10.1128/JVI.01731-10. Epub 2010 Nov 24.

22.

Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria.

Gdynia G, Keith M, Kopitz J, Bergmann M, Fassl A, Weber AN, George J, Kees T, Zentgraf HW, Wiestler OD, Schirmacher P, Roth W.

Cancer Res. 2010 Nov 1;70(21):8558-68. doi: 10.1158/0008-5472.CAN-10-0204. Epub 2010 Oct 19.

23.

A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata.

Rickelt S, Rizzo S, Doerflinger Y, Zentgraf H, Basso C, Gerosa G, Thiene G, Moll R, Franke WW.

Mod Pathol. 2010 Nov;23(11):1429-37. doi: 10.1038/modpathol.2010.138. Epub 2010 Aug 6.

24.

Sphingolipid rheostat alterations related to transformation can be exploited for specific induction of lysosomal cell death in murine and human glioma.

Mora R, Dokic I, Kees T, Hüber CM, Keitel D, Geibig R, Brügge B, Zentgraf H, Brady NR, Régnier-Vigouroux A.

Glia. 2010 Aug 15;58(11):1364-83. doi: 10.1002/glia.21013.

PMID:
20607862
25.

IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody.

Andrulis M, Capper D, Meyer J, Penzel R, Hartmann C, Zentgraf H, von Deimling A.

Haematologica. 2010 Oct;95(10):1797-8. doi: 10.3324/haematol.2010.024430. Epub 2010 Jun 9. No abstract available.

26.

Anti-CD4-targeted gold nanoparticles induce specific contrast enhancement of peripheral lymph nodes in X-ray computed tomography of live mice.

Eck W, Nicholson AI, Zentgraf H, Semmler W, Bartling S.

Nano Lett. 2010 Jul 14;10(7):2318-22. doi: 10.1021/nl101019s.

PMID:
20496900
27.

Analysis of prototype foamy virus particle-host cell interaction with autofluorescent retroviral particles.

Stirnnagel K, Lüftenegger D, Stange A, Swiersy A, Müllers E, Reh J, Stanke N, Grosse A, Chiantia S, Keller H, Schwille P, Hanenberg H, Zentgraf H, Lindemann D.

Retrovirology. 2010 May 17;7:45. doi: 10.1186/1742-4690-7-45.

28.

N-glycosylation of carnosinase influences protein secretion and enzyme activity: implications for hyperglycemia.

Riedl E, Koeppel H, Pfister F, Peters V, Sauerhoefer S, Sternik P, Brinkkoetter P, Zentgraf H, Navis G, Henning RH, Van Den Born J, Bakker SJ, Janssen B, van der Woude FJ, Yard BA.

Diabetes. 2010 Aug;59(8):1984-90. doi: 10.2337/db09-0868. Epub 2010 May 11.

29.

The PEA-15 protein regulates autophagy via activation of JNK.

Böck BC, Tagscherer KE, Fassl A, Krämer A, Oehme I, Zentgraf HW, Keith M, Roth W.

J Biol Chem. 2010 Jul 9;285(28):21644-54. doi: 10.1074/jbc.M109.096628. Epub 2010 May 7.

30.

Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast.

Meitinger F, Petrova B, Lombardi IM, Bertazzi DT, Hub B, Zentgraf H, Pereira G.

J Cell Sci. 2010 Jun 1;123(Pt 11):1851-61. doi: 10.1242/jcs.063891. Epub 2010 May 4.

31.

Through its nonstructural protein NS1, parvovirus H-1 induces apoptosis via accumulation of reactive oxygen species.

Hristov G, Krämer M, Li J, El-Andaloussi N, Mora R, Daeffler L, Zentgraf H, Rommelaere J, Marchini A.

J Virol. 2010 Jun;84(12):5909-22. doi: 10.1128/JVI.01797-09. Epub 2010 Apr 7.

32.

Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing.

Andrulis M, Capper D, Luft T, Hartmann C, Zentgraf H, von Deimling A.

Leuk Res. 2010 Aug;34(8):1091-3. doi: 10.1016/j.leukres.2010.02.014. Epub 2010 Mar 12.

PMID:
20227112
33.

Small intestinal mucosa expression of putative chaperone fls485.

Reinartz A, Ehling J, Franz S, Simon V, Bravo IG, Tessmer C, Zentgraf H, Lyer S, Schneider U, Köster J, Raupach K, Kämmerer E, Klaus C, Tischendorf JJ, Kopitz J, Alonso A, Gassler N.

BMC Gastroenterol. 2010 Mar 7;10:27. doi: 10.1186/1471-230X-10-27.

34.

FXYD3 expression in gliomas and its clinicopathological significance.

Wang MW, Gu P, Zhang ZY, Zhu ZL, Geng Y, Kayed H, Zentgraf H, Sun XF.

Oncol Res. 2009;18(4):133-9.

PMID:
20112499
35.

Hepatitis B virus overexpresses suppressor of cytokine signaling-3 (SOCS3) thereby contributing to severity of inflammation in the liver.

Koeberlein B, zur Hausen A, Bektas N, Zentgraf H, Chin R, Nguyen LT, Kandolf R, Torresi J, Bock CT.

Virus Res. 2010 Mar;148(1-2):51-9. doi: 10.1016/j.virusres.2009.12.003. Epub 2009 Dec 29.

PMID:
20005910
36.

Expression of FXYD3 protein in relation to biological and clinicopathological variables in colorectal cancers.

Widegren E, Onnesjö S, Arbman G, Kayed H, Zentgraf H, Kleeff J, Zhang H, Sun XF.

Chemotherapy. 2009;55(6):407-13. doi: 10.1159/000263227. Epub 2009 Dec 2.

PMID:
19955746
37.

Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects.

Loges NT, Olbrich H, Becker-Heck A, Häffner K, Heer A, Reinhard C, Schmidts M, Kispert A, Zariwala MA, Leigh MW, Knowles MR, Zentgraf H, Seithe H, Nürnberg G, Nürnberg P, Reinhardt R, Omran H.

Am J Hum Genet. 2009 Dec;85(6):883-9. doi: 10.1016/j.ajhg.2009.10.018.

38.

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors.

Capper D, Weissert S, Balss J, Habel A, Meyer J, Jäger D, Ackermann U, Tessmer C, Korshunov A, Zentgraf H, Hartmann C, von Deimling A.

Brain Pathol. 2010 Jan;20(1):245-54. doi: 10.1111/j.1750-3639.2009.00352.x. Epub 2009 Oct 27.

PMID:
19903171
39.

Circulating fibronectin affects bone matrix, whereas osteoblast fibronectin modulates osteoblast function.

Bentmann A, Kawelke N, Moss D, Zentgraf H, Bala Y, Berger I, Gasser JA, Nakchbandi IA.

J Bone Miner Res. 2010 Apr;25(4):706-15. doi: 10.1359/jbmr.091011.

40.

Monoclonal antibody specific for IDH1 R132H mutation.

Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A.

Acta Neuropathol. 2009 Nov;118(5):599-601. doi: 10.1007/s00401-009-0595-z. Epub 2009 Oct 2.

PMID:
19798509
41.

RGD-labeled USPIO inhibits adhesion and endocytotic activity of alpha v beta3-integrin-expressing glioma cells and only accumulates in the vascular tumor compartment.

Kiessling F, Huppert J, Zhang C, Jayapaul J, Zwick S, Woenne EC, Mueller MM, Zentgraf H, Eisenhut M, Addadi Y, Neeman M, Semmler W.

Radiology. 2009 Nov;253(2):462-9. doi: 10.1148/radiol.2532081815. Epub 2009 Sep 29.

PMID:
19789239
42.

Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus.

Chin R, Nachbur U, Earnest-Silveira L, Bankovacki A, Koeberlein B, Zentgraf H, Bock CT, Silke J, Torresi J.

Virus Res. 2010 Jan;147(1):7-16. doi: 10.1016/j.virusres.2009.09.012. Epub 2009 Sep 26.

PMID:
19786052
43.

SLA/LP/tRNP((Ser)Sec) antigen in autoimmune hepatitis: identification of the native protein in human hepatic cell extract.

Volkmann M, Luithle D, Zentgraf H, Schnölzer M, Fiedler S, Heid H, Schulze-Bergkamen A, Strassburg CP, Gehrke SG, Manns MP.

J Autoimmun. 2010 Feb;34(1):59-65. doi: 10.1016/j.jaut.2009.07.005. Epub 2009 Aug 14.

PMID:
19683415
44.

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1.

Tibelius A, Marhold J, Zentgraf H, Heilig CE, Neitzel H, Ducommun B, Rauch A, Ho AD, Bartek J, Krämer A.

J Cell Biol. 2009 Jun 29;185(7):1149-57. doi: 10.1083/jcb.200810159. Epub 2009 Jun 22.

45.

Interference of amino-terminal desmin fragments with desmin filament formation.

Bär H, Sharma S, Kleiner H, Mücke N, Zentgraf H, Katus HA, Aebi U, Herrmann H.

Cell Motil Cytoskeleton. 2009 Nov;66(11):986-99. doi: 10.1002/cm.20396.

PMID:
19530175
46.

Autophagy-A double-edged sword in oncology.

Apel A, Zentgraf H, Büchler MW, Herr I.

Int J Cancer. 2009 Sep 1;125(5):991-5. doi: 10.1002/ijc.24500. Review.

47.

Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway.

Francis RJ, Chatterjee B, Loges NT, Zentgraf H, Omran H, Lo CW.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1067-75. doi: 10.1152/ajplung.00001.2009. Epub 2009 Apr 3.

48.

Subcellular mislocalization of mutant hepatitis B X proteins contributes to modulation of STAT/SOCS signaling in hepatocellular carcinoma.

Bock CT, Toan NL, Koeberlein B, Song le H, Chin R, Zentgraf H, Kandolf R, Torresi J.

Intervirology. 2008;51(6):432-43. doi: 10.1159/000209672. Epub 2009 Mar 26.

PMID:
19321929
49.

Expression of FXYD-3 is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy.

Loftås P, Onnesjö S, Widegren E, Adell G, Kayed H, Kleeff J, Zentgraf H, Sun XF.

Int J Radiat Oncol Biol Phys. 2009 Sep 1;75(1):137-42. doi: 10.1016/j.ijrobp.2008.10.076. Epub 2009 Mar 14.

PMID:
19289258
50.

Remodelling of VipA/VipB tubules by ClpV-mediated threading is crucial for type VI protein secretion.

Bönemann G, Pietrosiuk A, Diemand A, Zentgraf H, Mogk A.

EMBO J. 2009 Feb 18;28(4):315-25. doi: 10.1038/emboj.2008.269. Epub 2009 Jan 8.

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