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Items: 1 to 50 of 331

1.

Real-time breath analysis reveals specific metabolic signatures of COPD exacerbations.

Gaugg MT, Nussbaumer-Ochsner Y, Bregy L, Engler A, Stebler N, Gaisl T, Bruderer T, Nowak N, Sinues PM, Zenobi R, Kohler M.

Chest. 2019 Jan 24. pii: S0012-3692(19)30062-5. doi: 10.1016/j.chest.2018.12.023. [Epub ahead of print]

PMID:
30685334
2.

Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.

Gaugg MT, Engler A, Bregy L, Nussbaumer-Ochsner Y, Eiffert L, Bruderer T, Zenobi R, Sinues P, Kohler M.

Respirology. 2019 Jan 25. doi: 10.1111/resp.13465. [Epub ahead of print]

PMID:
30681243
3.

Microfluidic Platform for Multimodal Analysis of Enzyme Secretion in Nanoliter Droplet Arrays.

Haidas D, Bachler S, Köhler M, Blank LM, Zenobi R, Dittrich PS.

Anal Chem. 2019 Feb 5;91(3):2066-2073. doi: 10.1021/acs.analchem.8b04506. Epub 2019 Jan 8.

PMID:
30571917
4.

Simulated Molecular Evolution for Anticancer Peptide Design.

Neuhaus CS, Gabernet G, Steuer C, Root K, Hiss JA, Zenobi R, Schneider G.

Angew Chem Int Ed Engl. 2019 Feb 4;58(6):1674-1678. doi: 10.1002/anie.201811215. Epub 2019 Jan 9.

PMID:
30506920
5.

Insights into the Basal Activity and Activation Mechanism of the β1 Adrenergic Receptor Using Native Mass Spectrometry.

Gavriilidou AFM, Hunziker H, Mayer D, Vuckovic Z, Veprintsev DB, Zenobi R.

J Am Soc Mass Spectrom. 2018 Dec 3. doi: 10.1007/s13361-018-2110-z. [Epub ahead of print]

PMID:
30511235
6.

Supramolecular Capsules: Strong versus Weak Chalcogen Bonding.

Riwar LJ, Trapp N, Root K, Zenobi R, Diederich F.

Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17259-17264. doi: 10.1002/anie.201812095. Epub 2018 Nov 27.

PMID:
30480857
7.

Photochemical Creation of Covalent Organic 2D Monolayer Objects in Defined Shapes via a Lithographic 2D Polymerization.

Servalli M, Celebi K, Payamyar P, Zheng L, Položij M, Lowe B, Kuc A, Schwarz T, Thorwarth K, Borgschulte A, Heine T, Zenobi R, Schlüter AD.

ACS Nano. 2018 Nov 27;12(11):11294-11306. doi: 10.1021/acsnano.8b05964. Epub 2018 Oct 24.

PMID:
30354049
8.

Tip-enhanced Raman spectroscopy: principles, practice, and applications to nanospectroscopic imaging of 2D materials.

Shao F, Zenobi R.

Anal Bioanal Chem. 2019 Jan;411(1):37-61. doi: 10.1007/s00216-018-1392-0. Epub 2018 Oct 10. Review.

PMID:
30306237
9.

Plasmon-Driven Photocatalysis Leads to Products Known from E-beam and X-ray-Induced Surface Chemistry.

Szczerbiński J, Gyr L, Kaeslin J, Zenobi R.

Nano Lett. 2018 Nov 14;18(11):6740-6749. doi: 10.1021/acs.nanolett.8b02426. Epub 2018 Oct 8.

PMID:
30277787
10.

Multiple Sclerosis: kFLC index values related to gender.

Pieri M, Zenobi R, Morello M, Storto M, Buttari F, Centonze D, Bernardini S, Dessi M.

Mult Scler Relat Disord. 2018 Nov;26:58-60. doi: 10.1016/j.msard.2018.08.018. Epub 2018 Aug 30.

PMID:
30223231
11.

Thermal Denaturation of DNA G-Quadruplexes and Their Complexes with Ligands: Thermodynamic Analysis of the Multiple States Revealed by Mass Spectrometry.

Marchand A, Rosu F, Zenobi R, Gabelica V.

J Am Chem Soc. 2018 Oct 3;140(39):12553-12565. doi: 10.1021/jacs.8b07302. Epub 2018 Sep 18.

PMID:
30183275
12.

Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor.

Root K, Barylyuk K, Schwab A, Thelemann J, Illarionov B, Geist JG, Gräwert T, Bacher A, Fischer M, Diederich F, Zenobi R.

Chem Sci. 2018 Jun 18;9(27):5976-5986. doi: 10.1039/c8sc00814k. eCollection 2018 Jul 21.

13.

High-throughput screening of PAHs and polar trace contaminants in water matrices by direct solid-phase microextraction coupled to a dielectric barrier discharge ionization source.

Huba AK, Mirabelli MF, Zenobi R.

Anal Chim Acta. 2018 Nov 7;1030:125-132. doi: 10.1016/j.aca.2018.05.050. Epub 2018 May 21.

PMID:
30032761
14.

Nephelometric assay of urine free light chains: an alternative and early clinical test for Bence-Jones protein quantification.

Pieri M, Pignalosa S, Franceschini L, Rizzo M, Cantonetti M, Zenobi R, Bernardini S, Dessi M.

Clin Chem Lab Med. 2018 Nov 27;56(12):e313-e315. doi: 10.1515/cclm-2018-0402. No abstract available.

PMID:
29935112
15.

Application of Native ESI-MS to Characterize Interactions between Compounds Derived from Fragment-Based Discovery Campaigns and Two Pharmaceutically Relevant Proteins.

Gavriilidou AFM, Holding FP, Coyle JE, Zenobi R.

SLAS Discov. 2018 Oct;23(9):951-959. doi: 10.1177/2472555218775921. Epub 2018 May 31.

PMID:
29852073
16.

Real-Time Monitoring of Tricarboxylic Acid Metabolites in Exhaled Breath.

Tejero Rioseras A, Singh KD, Nowak N, Gaugg MT, Bruderer T, Zenobi R, Sinues PM.

Anal Chem. 2018 Jun 5;90(11):6453-6460. doi: 10.1021/acs.analchem.7b04600. Epub 2018 May 16.

PMID:
29767961
17.

Direct Nanospectroscopic Verification of the Amyloid Aggregation Pathway.

Lipiec E, Perez-Guaita D, Kaderli J, Wood BR, Zenobi R.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8519-8524. doi: 10.1002/anie.201803234. Epub 2018 Jun 6.

PMID:
29749066
18.

Native Electrospray Ionization Mass Spectrometry Reveals Multiple Facets of Aptamer-Ligand Interactions: From Mechanism to Binding Constants.

Gülbakan B, Barylyuk K, Schneider P, Pillong M, Schneider G, Zenobi R.

J Am Chem Soc. 2018 Jun 20;140(24):7486-7497. doi: 10.1021/jacs.7b13044. Epub 2018 Jun 1.

PMID:
29733584
19.

Chemical Mapping of Nanodefects within 2D Covalent Monolayers by Tip-Enhanced Raman Spectroscopy.

Shao F, Dai W, Zhang Y, Zhang W, Schlüter AD, Zenobi R.

ACS Nano. 2018 May 22;12(5):5021-5029. doi: 10.1021/acsnano.8b02513. Epub 2018 Apr 20.

PMID:
29659244
20.

Shell-Isolated Tip-Enhanced Raman and Fluorescence Spectroscopy.

Huang YP, Huang SC, Wang XJ, Bodappa N, Li CY, Yin H, Su HS, Meng M, Zhang H, Ren B, Yang ZL, Zenobi R, Tian ZQ, Li JF.

Angew Chem Int Ed Engl. 2018 Jun 18;57(25):7523-7527. doi: 10.1002/anie.201802892. Epub 2018 Apr 26.

PMID:
29645335
21.

Binding Specificities of Nanobody•Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry.

Köhler M, Neff C, Perez C, Brunner C, Pardon E, Steyaert J, Schneider G, Locher KP, Zenobi R.

Anal Chem. 2018 Apr 17;90(8):5306-5313. doi: 10.1021/acs.analchem.8b00236. Epub 2018 Apr 4.

PMID:
29562137
22.

Real-time exhaled breath analysis in patients with cystic fibrosis and controls.

Gaisl T, Bregy L, Stebler N, Gaugg MT, Bruderer T, García-Gómez D, Moeller A, Singer F, Schwarz EI, Benden C, M-L Sinues P, Zenobi R, Kohler M.

J Breath Res. 2018 Apr 30;12(3):036013. doi: 10.1088/1752-7163/aab7fd.

PMID:
29555894
23.

Solid-Phase Microextraction Coupled to Capillary Atmospheric Pressure Photoionization-Mass Spectrometry for Direct Analysis of Polar and Nonpolar Compounds.

Mirabelli MF, Zenobi R.

Anal Chem. 2018 Apr 17;90(8):5015-5022. doi: 10.1021/acs.analchem.7b04514. Epub 2018 Mar 27.

PMID:
29537821
24.

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

Gavriilidou AFM, Holding FP, Mayer D, Coyle JE, Veprintsev DB, Zenobi R.

Biochemistry. 2018 Mar 20;57(11):1685-1689. doi: 10.1021/acs.biochem.7b01270. Epub 2018 Mar 8.

PMID:
29499117
25.

Translating secondary electrospray ionization-high-resolution mass spectrometry to the clinical environment.

Singh KD, Del Miguel GV, Gaugg MT, Ibañez AJ, Zenobi R, Kohler M, Frey U, Sinues PM.

J Breath Res. 2018 Feb 7;12(2):027113. doi: 10.1088/1752-7163/aa9ee3.

PMID:
29411710
26.

Mechanistic Understanding Leads to Increased Ionization Efficiency and Selectivity in Dielectric Barrier Discharge Ionization Mass Spectrometry: A Case Study with Perfluorinated Compounds.

Gyr L, Wolf JC, Franzke J, Zenobi R.

Anal Chem. 2018 Feb 20;90(4):2725-2731. doi: 10.1021/acs.analchem.7b04711. Epub 2018 Feb 2.

PMID:
29356499
27.
28.

High-Throughput Monitoring of Cocaine and Its Metabolites in Hair Using Microarrays for Mass Spectrometry and Matrix-Assisted Laser Desorption/Ionization-Tandem Mass Spectrometry.

Kernalléguen A, Steinhoff R, Bachler S, Dittrich PS, Saint-Marcoux F, El Bakhi S, Vorspan F, Léonetti G, Lafitte D, Pélissier-Alicot AL, Zenobi R.

Anal Chem. 2018 Feb 6;90(3):2302-2309. doi: 10.1021/acs.analchem.7b04693. Epub 2018 Jan 22.

PMID:
29309134
29.

Vibrational Changes Induced by Electron Transfer in Surface Bound Azurin Metalloprotein Studied by Tip-Enhanced Raman Spectroscopy and Scanning Tunneling Microscopy.

Kradolfer S, Lipiec E, Baldacchini C, Bizzarri AR, Cannistraro S, Zenobi R.

ACS Nano. 2017 Dec 26;11(12):12824-12831. doi: 10.1021/acsnano.7b07768. Epub 2017 Dec 11.

PMID:
29202236
30.

Nanoscale Chemical Imaging of Reversible Photoisomerization of an Azobenzene-Thiol Self-Assembled Monolayer by Tip-Enhanced Raman Spectroscopy.

Zheng LQ, Wang X, Shao F, Hegner M, Zenobi R.

Angew Chem Int Ed Engl. 2018 Jan 22;57(4):1025-1029. doi: 10.1002/anie.201710443. Epub 2017 Dec 27.

PMID:
29178528
31.

The capillary gap sampler, a new microfluidic platform for direct coupling of automated solid-phase microextraction with ESI-MS.

Ghiasikhou S, da Silva MF, Zhu Y, Zenobi R.

Anal Bioanal Chem. 2017 Nov;409(29):6873-6883. doi: 10.1007/s00216-017-0652-8. Epub 2017 Oct 18.

PMID:
29046923
32.

Spontaneous non-canonical assembly of CcmK hexameric components from β-carboxysome shells of cyanobacteria.

Garcia-Alles LF, Lesniewska E, Root K, Aubry N, Pocholle N, Mendoza CI, Bourillot E, Barylyuk K, Pompon D, Zenobi R, Reguera D, Truan G.

PLoS One. 2017 Sep 21;12(9):e0185109. doi: 10.1371/journal.pone.0185109. eCollection 2017.

33.

Structural Characterization of a Covalent Monolayer Sheet Obtained by Two-Dimensional Polymerization at an Air/Water Interface.

Müller V, Shao F, Baljozovic M, Moradi M, Zhang Y, Jung T, Thompson WB, King BT, Zenobi R, Schlüter AD.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15262-15266. doi: 10.1002/anie.201707140. Epub 2017 Nov 2.

PMID:
28922539
34.

Metabolic effects of inhaled salbutamol determined by exhaled breath analysis.

Gaugg MT, Engler A, Nussbaumer-Ochsner Y, Bregy L, Stöberl AS, Gaisl T, Bruderer T, Zenobi R, Kohler M, Martinez-Lozano Sinues P.

J Breath Res. 2017 Sep 13;11(4):046004. doi: 10.1088/1752-7163/aa7caa.

35.

Mass-Spectrometric Detection of Omega-Oxidation Products of Aliphatic Fatty Acids in Exhaled Breath.

Gaugg MT, Bruderer T, Nowak N, Eiffert L, Martinez-Lozano Sinues P, Kohler M, Zenobi R.

Anal Chem. 2017 Oct 3;89(19):10329-10334. doi: 10.1021/acs.analchem.7b02092. Epub 2017 Sep 14.

PMID:
28856884
36.

Isotope labeling to determine the dynamics of metabolic response in CHO cell perfusion bioreactors using MALDI-TOF-MS.

Karst DJ, Steinhoff RF, Kopp MRG, Soos M, Zenobi R, Morbidelli M.

Biotechnol Prog. 2017 Nov;33(6):1630-1639. doi: 10.1002/btpr.2539. Epub 2017 Sep 7.

PMID:
28840654
37.

KFLC Index utility in multiple sclerosis diagnosis: Further confirmation.

Pieri M, Storto M, Pignalosa S, Zenobi R, Buttari F, Bernardini S, Centonze D, Dessi M.

J Neuroimmunol. 2017 Aug 15;309:31-33. doi: 10.1016/j.jneuroim.2017.05.007. Epub 2017 May 12.

PMID:
28601282
38.

Nanoscale Chemical Imaging of Interfacial Monolayers by Tip-Enhanced Raman Spectroscopy.

Shao F, Müller V, Zhang Y, Schlüter AD, Zenobi R.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9361-9366. doi: 10.1002/anie.201703800. Epub 2017 Jul 4.

PMID:
28597527
39.

Insight into Signal Response of Protein Ions in Native ESI-MS from the Analysis of Model Mixtures of Covalently Linked Protein Oligomers.

Root K, Wittwer Y, Barylyuk K, Anders U, Zenobi R.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1863-1875. doi: 10.1007/s13361-017-1690-3. Epub 2017 Jun 7.

PMID:
28593376
40.

Observing Proton Transfer Reactions Inside the MALDI Plume: Experimental and Theoretical Insight into MALDI Gas-Phase Reactions.

Mirabelli MF, Zenobi R.

J Am Soc Mass Spectrom. 2017 Aug;28(8):1676-1686. doi: 10.1007/s13361-017-1677-0. Epub 2017 Apr 27.

PMID:
28451953
41.

Atmospheric pressure soft ionization for gas chromatography with dielectric barrier discharge ionization-mass spectrometry (GC-DBDI-MS).

Mirabelli MF, Wolf JC, Zenobi R.

Analyst. 2017 May 30;142(11):1909-1915. doi: 10.1039/c7an00245a.

PMID:
28443843
42.

Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.

Perez C, Köhler M, Janser D, Pardon E, Steyaert J, Zenobi R, Locher KP.

Sci Rep. 2017 Apr 19;7:46641. doi: 10.1038/srep46641.

43.

Author's response to Letter to the Editor by N. Messaoudani, R. Djidjik and M. Ghaffor published in JNI 266 (2014) entitled "Comments on CSF κFLC assay evaluation in assessing intrathecal synthesis".

Pieri M, Pignalosa S, Zenobi R, Dessi M.

J Neuroimmunol. 2017 May 15;306:19. doi: 10.1016/j.jneuroim.2017.02.013. Epub 2017 Feb 20. No abstract available.

PMID:
28385182
44.

Single-Cell Mass Spectrometry of Metabolites Extracted from Live Cells by Fluidic Force Microscopy.

Guillaume-Gentil O, Rey T, Kiefer P, Ibáñez AJ, Steinhoff R, Brönnimann R, Dorwling-Carter L, Zambelli T, Zenobi R, Vorholt JA.

Anal Chem. 2017 May 2;89(9):5017-5023. doi: 10.1021/acs.analchem.7b00367. Epub 2017 Apr 11.

PMID:
28363018
45.

Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization.

Japaridze A, Muskhelishvili G, Benedetti F, Gavriilidou AF, Zenobi R, De Los Rios P, Longo G, Dietler G.

Nano Lett. 2017 Mar 8;17(3):1938-1948. doi: 10.1021/acs.nanolett.6b05294. Epub 2017 Feb 16.

PMID:
28191853
46.

Gauging circadian variation in ketamine metabolism by real-time breath analysis.

Martinez-Lozano Sinues P, Kohler M, Brown SA, Zenobi R, Dallmann R.

Chem Commun (Camb). 2017 Feb 14;53(14):2264-2267. doi: 10.1039/c6cc09061c.

PMID:
28150005
47.

Low-Temperature Wet Conformal Nickel Silicide Deposition for Transistor Technology through an Organometallic Approach.

Lin TH, Margossian T, De Marchi M, Thammasack M, Zemlyanov D, Kumar S, Jagielski J, Zheng LQ, Shih CJ, Zenobi R, De Micheli G, Baudouin D, Gaillardon PE, Copéret C.

ACS Appl Mater Interfaces. 2017 Feb 8;9(5):4948-4955. doi: 10.1021/acsami.6b13852. Epub 2017 Jan 25.

PMID:
28078888
48.

Intracellular CHO Cell Metabolite Profiling Reveals Steady-State Dependent Metabolic Fingerprints in Perfusion Culture.

Karst DJ, Steinhoff RF, Kopp MRG, Serra E, Soos M, Zenobi R, Morbidelli M.

Biotechnol Prog. 2017 Jul;33(4):879-890. doi: 10.1002/btpr.2421. Epub 2017 Mar 3.

PMID:
27997765
49.

Strongly enhanced Raman scattering of Cu-phthalocyanine sandwiched between graphene and Au(111).

Lin WI, Gholami MF, Beyer P, Severin N, Shao F, Zenobi R, Rabe JP.

Chem Commun (Camb). 2017 Jan 5;53(4):724-727. doi: 10.1039/c6cc08672a.

PMID:
27990530
50.

SPRi-MALDI MS: characterization and identification of a kinase from cell lysate by specific interaction with different designed ankyrin repeat proteins.

Anders U, Schaefer JV, Hibti FE, Frydman C, Suckau D, Plückthun A, Zenobi R.

Anal Bioanal Chem. 2017 Mar;409(7):1827-1836. doi: 10.1007/s00216-016-0127-3. Epub 2016 Dec 16.

PMID:
27987025

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