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Items: 9


Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.

Record J, Malinova D, Zenner HL, Plagnol V, Nowak K, Syed F, Bouma G, Curtis J, Gilmour K, Cale C, Hackett S, Charras G, Moulding D, Nejentsev S, Thrasher AJ, Burns SO.

Blood. 2015 Sep 24;126(13):1527-35. doi: 10.1182/blood-2014-12-611012. Epub 2015 Jul 29.


Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.

Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nürnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, Nejentsev S.

Nat Genet. 2015 May;47(5):523-527. doi: 10.1038/ng.3248. Epub 2015 Mar 16.


Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity.

Zenner HL, Mauricio R, Banting G, Crump CM.

J Virol. 2013 Dec;87(24):13115-23. doi: 10.1128/JVI.02167-13. Epub 2013 Sep 25.


A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.

Griffiths SJ, Koegl M, Boutell C, Zenner HL, Crump CM, Pica F, Gonzalez O, Friedel CC, Barry G, Martin K, Craigon MH, Chen R, Kaza LN, Fossum E, Fazakerley JK, Efstathiou S, Volpi A, Zimmer R, Ghazal P, Haas J.

PLoS Pathog. 2013;9(8):e1003514. doi: 10.1371/journal.ppat.1003514. Epub 2013 Aug 8.


LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia.

Burns SO, Zenner HL, Plagnol V, Curtis J, Mok K, Eisenhut M, Kumararatne D, Doffinger R, Thrasher AJ, Nejentsev S.

J Allergy Clin Immunol. 2012 Dec;130(6):1428-32. doi: 10.1016/j.jaci.2012.07.035. Epub 2012 Sep 14. No abstract available.


Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles.

Ren Y, Bell S, Zenner HL, Lau SY, Crump CM.

J Gen Virol. 2012 Feb;93(Pt 2):319-29. doi: 10.1099/vir.0.035444-0. Epub 2011 Oct 19.


Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment.

Zenner HL, Yoshimura S, Barr FA, Crump CM.

J Virol. 2011 Aug;85(16):8012-21. doi: 10.1128/JVI.00500-11. Epub 2011 Jun 15.


Formation and function of Weibel-Palade bodies.

Metcalf DJ, Nightingale TD, Zenner HL, Lui-Roberts WW, Cutler DF.

J Cell Sci. 2008 Jan 1;121(Pt 1):19-27.


High-pressure freezing provides insights into Weibel-Palade body biogenesis.

Zenner HL, Collinson LM, Michaux G, Cutler DF.

J Cell Sci. 2007 Jun 15;120(Pt 12):2117-25. Epub 2007 May 29.

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