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The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells.

Hou D, He F, Ma L, Cao M, Zhou Z, Wei Z, Xue Y, Sang X, Chong H, Tian C, Zheng S, Li J, Zen K, Chen X, Hong Z, Zhang CY, Jiang X.

J Nutr Biochem. 2018 Apr 8;57:197-205. doi: 10.1016/j.jnutbio.2018.03.026. [Epub ahead of print]


Sustained Effectiveness of Cilostazol After Endovascular Treatment of Femoropopliteal Lesions: Midterm Follow-up From the Sufficient Treatment of Peripheral Intervention by Cilostazol (STOP-IC) Study.

Soga Y, Hamasaki T, Edahiro R, Iida O, Inoue N, Suzuki K, Yokoi Y, Kawasaki D, Zen K, Urasawa K, Aodo K; STOP-IC investigators.

J Endovasc Ther. 2018 Jun;25(3):306-312. doi: 10.1177/1526602818771358. Epub 2018 Apr 30.


Comparison of commercial exosome isolation kits for circulating exosomal microRNA profiling.

Ding M, Wang C, Lu X, Zhang C, Zhou Z, Chen X, Zhang CY, Zen K, Zhang C.

Anal Bioanal Chem. 2018 Jun;410(16):3805-3814. doi: 10.1007/s00216-018-1052-4. Epub 2018 Apr 18.


Contemporary critical limb ischemia: Asian multidisciplinary consensus statement on the collaboration between endovascular therapy and wound care.

Kawarada O, Zen K, Hozawa K, Ayabe S, Huang HL, Choi D, Kim SH, Kim J, Kato T, Tsubakimoto Y, Nakama T, Ichihashi S, Fujimura N, Higashimori A, Fujihara M, Sato T, Yan BP, Pang SY, Wongwanit C, Leong YP, Chua B, George RK, Yokoi Y, Motomura H, Obara H.

Cardiovasc Interv Ther. 2018 Apr 13. doi: 10.1007/s12928-018-0523-z. [Epub ahead of print] Review.


Urinary miR-196a predicts disease progression in patients with chronic kidney disease.

Zhang C, Liang S, Cheng S, Li W, Wang X, Zheng C, Zeng C, Shi S, Xie L, Zen K, Liu Z.

J Transl Med. 2018 Apr 10;16(1):91. doi: 10.1186/s12967-018-1470-2.


Human cytomegalovirus reprogrammes haematopoietic progenitor cells into immunosuppressive monocytes to achieve latency.

Zhu D, Pan C, Sheng J, Liang H, Bian Z, Liu Y, Trang P, Wu J, Liu F, Zhang CY, Zen K.

Nat Microbiol. 2018 Apr;3(4):503-513. doi: 10.1038/s41564-018-0131-9. Epub 2018 Mar 27.


Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell-mediated inhibition of T-cell proliferation.

Bian Z, Abdelaal AM, Shi L, Liang H, Xiong L, Kidder K, Venkataramani M, Culpepper C, Zen K, Liu Y.

Eur J Immunol. 2018 Jun;48(6):1046-1058. doi: 10.1002/eji.201747355. Epub 2018 Mar 23.


Two-Wire Technique With a Gooseneck Snare to Bail Out the Tip Separation of a Crosser Catheter.

Kadoya Y, Zen K, Oda Y, Matoba S.

Vasc Endovascular Surg. 2018 May;52(4):299-303. doi: 10.1177/1538574418761270. Epub 2018 Feb 26.


Predictors of cardiac benefits of renal artery stenting from a multicentre retrospective registry.

Nakajima Y, Kawarada O, Higashimori A, Yokoi Y, Zen K, Anzai H, Doi H, Hokimoto S, Ito S, Kato T, Kume T, Shintani Y, Tanimoto S, Tsubakimoto Y, Utsunomiya M, Nishimura K, Yasuda S.

Heart Asia. 2017 Sep 14;9(2):e010934. doi: 10.1136/heartasia-2017-010934. eCollection 2017.


Vascular response to biolimus A-9 eluting stent in patients with shorter and prolonged dual antiplatelet therapy: optical coherence tomography sub-study of the NIPPON trial.

Kuroda K, Shinke T, Otake H, Kinutani H, Iijima R, Ako J, Okada H, Ito Y, Ando K, Anzai H, Tanaka H, Ueda Y, Takiuchi S, Nishida Y, Ohira H, Kawaguchi K, Kadotani M, Niinuma H, Omiya K, Morita T, Zen K, Yasaka Y, Inoue K, Ishiwata S, Ochiai M, Hamasaki T, Urasawa K, Kataoka T, Yoshiyama M, Fujii K, Inoue T, Kawata M, Yokoi H, Nakamura M; NIPPON investigators.

Heart Vessels. 2018 Feb 20. doi: 10.1007/s00380-018-1131-7. [Epub ahead of print]


The feedback loop between miR-21, PDCD4 and AP-1 functions as a driving force for renal fibrogenesis.

Sun Q, Miao J, Luo J, Yuan Q, Cao H, Su W, Zhou Y, Jiang L, Fang L, Dai C, Zen K, Yang J.

J Cell Sci. 2018 Mar 26;131(6). pii: jcs202317. doi: 10.1242/jcs.202317.


H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2.

Li X, Fu Z, Liang H, Wang Y, Qi X, Ding M, Sun X, Zhou Z, Huang Y, Gu H, Li L, Chen X, Li D, Zhao Q, Liu F, Wang H, Wang J, Zen K, Zhang CY.

Cell Res. 2018 Feb;28(2):157-171. doi: 10.1038/cr.2018.3. Epub 2018 Jan 12.


Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level.

Wang D, Sun X, Wei Y, Liang H, Yuan M, Jin F, Chen X, Liu Y, Zhang CY, Li L, Zen K.

Nucleic Acids Res. 2018 Feb 28;46(4):2012-2029. doi: 10.1093/nar/gkx1254.


Dissection of Glomerular Transcriptional Profile in Patients With Diabetic Nephropathy: SRGAP2a Protects Podocyte Structure and Function.

Pan Y, Jiang S, Hou Q, Qiu D, Shi J, Wang L, Chen Z, Zhang M, Duan A, Qin W, Zen K, Liu Z.

Diabetes. 2018 Apr;67(4):717-730. doi: 10.2337/db17-0755. Epub 2017 Dec 14.


PDE/cAMP/Epac/C/EBP-β Signaling Cascade Regulates Mitochondria Biogenesis of Tubular Epithelial Cells in Renal Fibrosis.

Ding H, Bai F, Cao H, Xu J, Fang L, Wu J, Yuan Q, Zhou Y, Sun Q, He W, Dai C, Zen K, Jiang L, Yang J.

Antioxid Redox Signal. 2018 Feb 22. doi: 10.1089/ars.2017.7041. [Epub ahead of print]


Salmonella small RNA fragment Sal-1 facilitates bacterial survival in infected cells via suppressing iNOS induction in a microRNA manner.

Zhao C, Zhou Z, Zhang T, Liu F, Zhang CY, Zen K, Gu H.

Sci Rep. 2017 Dec 5;7(1):16979. doi: 10.1038/s41598-017-17205-4.


Tumor conditions induce bone marrow expansion of granulocytic, but not monocytic, immunosuppressive leukocytes with increased CXCR2 expression in mice.

Bian Z, Shi L, Venkataramani M, Abdelaal AM, Culpepper C, Kidder K, Liang H, Zen K, Liu Y.

Eur J Immunol. 2018 Mar;48(3):532-542. doi: 10.1002/eji.201746976. Epub 2017 Dec 8.


Mid-aortic Syndrome: A Rare Cause of Juvenile Hypertension.

Kadoya Y, Zen K, Saburi M, Matoba S.

Intern Med. 2018 Feb 1;57(3):447. doi: 10.2169/internalmedicine.9337-17. Epub 2017 Nov 1. No abstract available.


NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.

Ju J, Chen A, Deng Y, Liu M, Wang Y, Wang Y, Nie M, Wang C, Ding H, Yao B, Gui T, Li X, Xu Z, Ma C, Song Y, Kvansakul M, Zen K, Zhang CY, Luo C, Fang M, Huang DCS, Allis CD, Tan R, Zeng CK, Wei J, Zhao Q.

Nat Commun. 2017 Oct 13;8(1):928. doi: 10.1038/s41467-017-00988-5.


miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer.

Hu X, Wang Y, Liang H, Fan Q, Zhu R, Cui J, Zhang W, Zen K, Zhang CY, Hou D, Zhou Z, Chen X.

Cell Death Dis. 2017 Oct 5;8(10):e3059. doi: 10.1038/cddis.2017.447.


MicroRNA-128-3p regulates mitomycin C-induced DNA damage response in lung cancer cells through repressing SPTAN1.

Zhang R, Liu C, Niu Y, Jing Y, Zhang H, Wang J, Yang J, Zen K, Zhang J, Zhang CY, Li D.

Oncotarget. 2016 Sep 28;8(35):58098-58107. doi: 10.18632/oncotarget.12300. eCollection 2017 Aug 29.


Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals.

Cui JY, Liang HW, Pan XL, Li D, Jiao N, Liu YH, Fu J, He XY, Sun GX, Zhang CL, Zhao CH, Li DH, Dai EY, Zen K, Zhang FM, Zhang CY, Chen X, Ling H.

PLoS One. 2017 Sep 14;12(9):e0184113. doi: 10.1371/journal.pone.0184113. eCollection 2017.


Plant microRNAs in larval food regulate honeybee caste development.

Zhu K, Liu M, Fu Z, Zhou Z, Kong Y, Liang H, Lin Z, Luo J, Zheng H, Wan P, Zhang J, Zen K, Chen J, Hu F, Zhang CY, Ren J, Chen X.

PLoS Genet. 2017 Aug 31;13(8):e1006946. doi: 10.1371/journal.pgen.1006946. eCollection 2017 Aug.


Intraluminal Fibrous Webs in Brachial Artery Fibromuscular Dysplasia.

Kadoya Y, Zen K, Matoba S.

JACC Cardiovasc Interv. 2017 Sep 11;10(17):1801-1802. doi: 10.1016/j.jcin.2017.05.035. Epub 2017 Aug 16. No abstract available.


Newly Designed Side-Grooved Guiding Sheath for the Endovascular Treatment of Superficial Femoral Artery Chronic Total Occlusion.

Kadoya Y, Zen K, Oda Y, Matoba S.

JACC Cardiovasc Interv. 2017 Aug 28;10(16):e151-e152. doi: 10.1016/j.jcin.2017.05.037. Epub 2017 Aug 2. No abstract available.


MicroRNA-125b-5p modulates the inflammatory state of macrophages via targeting B7-H4.

Diao W, Lu L, Li S, Chen J, Zen K, Li L.

Biochem Biophys Res Commun. 2017 Sep 30;491(4):912-918. doi: 10.1016/j.bbrc.2017.07.135. Epub 2017 Jul 25.


"Pseudo aortoiliac bifurcation" leading to significant plaque shifting in the endovascular treatment of an aortoiliac bifurcation lesion: a case report.

Kadoya Y, Kenzaka T, Naito D, Zen K, Matoba S.

BMC Cardiovasc Disord. 2017 Jul 4;17(1):179. doi: 10.1186/s12872-017-0614-2.


Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation.

Nakamura M, Iijima R, Ako J, Shinke T, Okada H, Ito Y, Ando K, Anzai H, Tanaka H, Ueda Y, Takiuchi S, Nishida Y, Ohira H, Kawaguchi K, Kadotani M, Niinuma H, Omiya K, Morita T, Zen K, Yasaka Y, Inoue K, Ishiwata S, Ochiai M, Hamasaki T, Yokoi H; NIPPON Investigators.

JACC Cardiovasc Interv. 2017 Jun 26;10(12):1189-1198. doi: 10.1016/j.jcin.2017.04.019.


Impact of Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction Who Arrived by Self-Transport - Acute Myocardial Infarction-Kyoto Multi-Center Risk Study Group.

Kodama N, Nakamura T, Yanishi K, Nakanishi N, Zen K, Yamano T, Shiraishi H, Shirayama T, Shiraishi J, Sawada T, Kohno Y, Kitamura M, Furukawa K, Matoba S.

Circ J. 2017 Oct 25;81(11):1693-1698. doi: 10.1253/circj.CJ-17-0083. Epub 2017 Jun 20.


Efficacy of CilostAzol for Below-the-Knee Artery Disease after Balloon AnGioplasty in PatiEnts with Severe Limb Ischemia (CABBAGE Trial).

Soga Y, Takahara M, Iida O, Yamauchi Y, Hirano K, Fukunaga M, Zen K, Suzuki K, Shintani Y, Miyashita Y, Tsuchiya T, Yamaoka T, Ando K.

Ann Vasc Surg. 2017 Nov;45:22-28. doi: 10.1016/j.avsg.2017.05.029. Epub 2017 Jun 6.


The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma.

Jin F, Wang Y, Zhu Y, Li S, Liu Y, Chen C, Wang X, Zen K, Li L.

Sci Rep. 2017 Jun 8;7(1):3089. doi: 10.1038/s41598-017-03407-3.


Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients.

Ding M, Wang X, Wang C, Liu X, Zen K, Wang W, Zhang CY, Zhang C.

J Transl Med. 2017 Jun 7;15(1):133. doi: 10.1186/s12967-017-1222-8.


A New Method for Hemostasis of a Pseudoaneurysm Using Autologous Blood.

Ueno D, Yanishi K, Zen K, Matoba S.

JACC Cardiovasc Interv. 2017 Jun 26;10(12):e115-e116. doi: 10.1016/j.jcin.2017.03.036. Epub 2017 May 31. No abstract available.


Late-onset Mitochondrial Cardiomyopathy Triggered by Anticancer Treatment.

Yamasaki T, Yanishi K, Tateishi S, Nakanishi N, Zen K, Nakamura T, Yamano T, Shiraishi H, Shirayama T, Matoba S.

Intern Med. 2017;56(11):1357-1361. doi: 10.2169/internalmedicine.56.8076. Epub 2017 Jun 1.


Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival.

Gu H, Zhao C, Zhang T, Liang H, Wang XM, Pan Y, Chen X, Zhao Q, Li D, Liu F, Zhang CY, Zen K.

Sci Rep. 2017 May 24;7(1):2392. doi: 10.1038/s41598-017-02669-1.


UCP2 attenuates apoptosis of tubular epithelial cells in renal ischemia-reperfusion injury.

Zhou Y, Cai T, Xu J, Jiang L, Wu J, Sun Q, Zen K, Yang J.

Am J Physiol Renal Physiol. 2017 Oct 1;313(4):F926-F937. doi: 10.1152/ajprenal.00118.2017. Epub 2017 Apr 19.


Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma.

Liu R, Zhang H, Zhang Y, Li S, Wang X, Wang X, Wang C, Liu B, Zen K, Zhang CY, Zhang C, Ba Y.

Tumour Biol. 2017 Apr;39(4):1010428317695031. doi: 10.1177/1010428317695031.


Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis.

Ding H, Jiang L, Xu J, Bai F, Zhou Y, Yuan Q, Luo J, Zen K, Yang J.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F561-F575. doi: 10.1152/ajprenal.00036.2017. Epub 2017 Feb 22.


Silencing miR-106b accelerates osteogenesis of mesenchymal stem cells and rescues against glucocorticoid-induced osteoporosis by targeting BMP2.

Liu K, Jing Y, Zhang W, Fu X, Zhao H, Zhou X, Tao Y, Yang H, Zhang Y, Zen K, Zhang C, Li D, Shi Q.

Bone. 2017 Apr;97:130-138. doi: 10.1016/j.bone.2017.01.014. Epub 2017 Jan 17.


MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy.

Jin F, Wang Y, Li M, Zhu Y, Liang H, Wang C, Wang F, Zhang CY, Zen K, Li L.

Cell Death Dis. 2017 Jan 12;8(1):e2540. doi: 10.1038/cddis.2016.461.


Drug-eluting stenting for femoropopliteal lesions, followed by cilostazol treatment, reduces stent restenosis in patients with symptomatic peripheral artery disease.

Zen K, Takahara M, Iida O, Soga Y, Kawasaki D, Nanto S, Yokoi H, Matoba S; ZEPHYR Investigators.

J Vasc Surg. 2017 Mar;65(3):720-725. doi: 10.1016/j.jvs.2016.10.098. Epub 2017 Jan 7.


Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23.

Wei Y, Wang D, Jin F, Bian Z, Li L, Liang H, Li M, Shi L, Pan C, Zhu D, Chen X, Hu G, Liu Y, Zhang CY, Zen K.

Nat Commun. 2017 Jan 9;8:14041. doi: 10.1038/ncomms14041.


HIC1 and miR-23~27~24 clusters form a double-negative feedback loop in breast cancer.

Wang Y, Liang H, Zhou G, Hu X, Liu Z, Jin F, Yu M, Sang J, Zhou Y, Fu Z, Zhang CY, Zhang W, Zen K, Chen X.

Cell Death Differ. 2017 Mar;24(3):421-432. doi: 10.1038/cdd.2016.136. Epub 2016 Dec 23.


miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancer.

Hong Y, Liang H, Uzair-Ur-Rehman, Wang Y, Zhang W, Zhou Y, Chen S, Yu M, Cui S, Liu M, Wang N, Ye C, Zhao C, Liu Y, Fan Q, Zhang CY, Sang J, Zen K, Chen X.

Sci Rep. 2016 Nov 18;6:37421. doi: 10.1038/srep37421.


miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL.

Wang Y, Chen L, Wu Z, Wang M, Jin F, Wang N, Hu X, Liu Z, Zhang CY, Zen K, Chen J, Liang H, Zhang Y, Chen X.

BMC Cancer. 2016 Nov 15;16(1):826.


A Simple Risk Stratification Model for ST-Elevation Myocardial Infarction (STEMI) from the Combination of Blood Examination Variables: Acute Myocardial Infarction-Kyoto Multi-Center Risk Study Group.

Yanishi K, Nakamura T, Nakanishi N, Yokota I, Zen K, Yamano T, Shiraishi H, Shirayama T, Shiraishi J, Sawada T, Kohno Y, Kitamura M, Furukawa K, Matoba S.

PLoS One. 2016 Nov 11;11(11):e0166391. doi: 10.1371/journal.pone.0166391. eCollection 2016.


Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5.

Pan C, Zhu D, Wang Y, Li L, Li D, Liu F, Zhang CY, Zen K.

PLoS Pathog. 2016 Nov 8;12(11):e1006007. doi: 10.1371/journal.ppat.1006007. eCollection 2016 Nov.


miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma.

Fan Q, Meng X, Liang H, Zhang H, Liu X, Li L, Li W, Sun W, Zhang H, Zen K, Zhang CY, Zhou Z, Chen X, Ba Y.

Protein Cell. 2016 Dec;7(12):899-912. doi: 10.1007/s13238-016-0316-z. Epub 2016 Nov 4.


Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.

Li J, Chen X, Yi J, Liu Y, Li D, Wang J, Hou D, Jiang X, Zhang J, Wang J, Zen K, Yang F, Zhang CY, Zhang Y.

PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.


Broad Infiltration of Macrophages Leads to a Proinflammatory State in Streptozotocin-Induced Hyperglycemic Mice.

Niu S, Bian Z, Tremblay A, Luo Y, Kidder K, Mansour A, Zen K, Liu Y.

J Immunol. 2016 Oct 15;197(8):3293-3301. Epub 2016 Sep 12.

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