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Papillary thyroid carcinoma with pleomorphic tumor giant cells in a pregnant woman - a case report.

Paulsson JO, Zedenius J, Juhlin CC.

BMC Endocr Disord. 2018 Jul 5;18(1):46. doi: 10.1186/s12902-018-0275-x.


TERT promoter mutational screening as a tool to predict malignant behaviour in follicular thyroid tumours-three examples from the clinical routine.

Hysek M, Paulsson JO, Wang N, Jatta K, Lindh C, Fuentes-Martinez N, Shabo I, Zedenius J, Juhlin CC.

Virchows Arch. 2018 Jun 2. doi: 10.1007/s00428-018-2386-1. [Epub ahead of print]


High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma.

Mu N, Juhlin CC, Tani E, Sofiadis A, Reihnér E, Zedenius J, Larsson C, Nilsson IL.

Endocrine. 2018 May 23. doi: 10.1007/s12020-018-1627-z. [Epub ahead of print]


Over-diagnosis of potential malignant behavior in MEN 2A-associated pheochromocytomas using the PASS and GAPP algorithms.

Stenman A, Zedenius J, Juhlin CC.

Langenbecks Arch Surg. 2018 May 19. doi: 10.1007/s00423-018-1679-9. [Epub ahead of print]


TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours.

Paulsson JO, Mu N, Shabo I, Wang N, Zedenius J, Larsson C, Juhlin CC.

Endocr Relat Cancer. 2018 Jul;25(7):723-733. doi: 10.1530/ERC-18-0050. Epub 2018 Apr 24.


Recovery of Voice After Reconstruction of the Recurrent Laryngeal Nerve and Adjuvant Nimodipine.

Mattsson P, Frostell A, Björck G, Persson JKE, Hakim R, Zedenius J, Svensson M.

World J Surg. 2018 Mar;42(3):632-638. doi: 10.1007/s00268-017-4235-9.


Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma.

Svahn F, Juhlin CC, Paulsson JO, Fotouhi O, Zedenius J, Larsson C, Stenman A.

Clin Endocrinol (Oxf). 2018 Feb;88(2):343-345. doi: 10.1111/cen.13513. Epub 2017 Nov 27. No abstract available.


Äntligen! Nytt program för adrenala incidentalom.

Zedenius J.

Lakartidningen. 2017 Sep 29;114. pii: ETTI. Swedish. No abstract available.


Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy.

Nilsson IL, Norenstedt S, Zedenius J, Pernow Y, Bränström R.

Surgery. 2017 Aug;162(2):429-436. doi: 10.1016/j.surg.2017.02.017. Epub 2017 May 15.


Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors.

Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin CC, Lu M, Höög A, Pastrián LG, Lamarca A, Soto VH, Zedenius J, Mendiola M, Lehtiö J, Kjellman M.

J Clin Endocrinol Metab. 2016 Oct;101(10):3616-3627. Epub 2016 Jul 26.


Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma.

Wang N, Kjellin H, Sofiadis A, Fotouhi O, Juhlin CC, Bäckdahl M, Zedenius J, Xu D, Lehtiö J, Larsson C.

Oncotarget. 2016 Apr 19;7(16):21332-46. doi: 10.18632/oncotarget.7237.


Minimally invasive follicular thyroid carcinomas: prognostic factors.

Stenson G, Nilsson IL, Mu N, Larsson C, Lundgren CI, Juhlin CC, Höög A, Zedenius J.

Endocrine. 2016 Aug;53(2):505-11. doi: 10.1007/s12020-016-0876-y. Epub 2016 Feb 8.


FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy.

Nilsson IL, Norenstedt S, Granath F, Zedenius J, Pernow Y, Larsson TE.

Surgery. 2016 Jan;159(1):211-7. doi: 10.1016/j.surg.2015.06.057. Epub 2015 Oct 2.


Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.

Åkerström T, Willenberg HS, Cupisti K, Ip J, Backman S, Moser A, Maharjan R, Robinson B, Iwen KA, Dralle H, D Volpe C, Bäckdahl M, Botling J, Stålberg P, Westin G, Walz MK, Lehnert H, Sidhu S, Zedenius J, Björklund P, Hellman P.

Endocr Relat Cancer. 2015 Oct;22(5):735-44. doi: 10.1530/ERC-15-0321.


Secretome protein signature of human gastrointestinal stromal tumor cells.

Berglund E, Daré E, Branca RM, Akcakaya P, Fröbom R, Berggren PO, Lui WO, Larsson C, Zedenius J, Orre L, Lehtiö J, Kim J, Bränström R.

Exp Cell Res. 2015 Aug 1;336(1):158-70. doi: 10.1016/j.yexcr.2015.05.004. Epub 2015 May 14.


Differential protein expression profiles of cyst fluid from papillary thyroid carcinoma and benign thyroid lesions.

Dinets A, Pernemalm M, Kjellin H, Sviatoha V, Sofiadis A, Juhlin CC, Zedenius J, Larsson C, Lehtiö J, Höög A.

PLoS One. 2015 May 15;10(5):e0126472. doi: 10.1371/journal.pone.0126472. eCollection 2015.


Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.

Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP, Carling T.

Hum Mol Genet. 2015 Apr 15;24(8):2318-29. doi: 10.1093/hmg/ddu749. Epub 2015 Jan 9.


Health-related quality of life after successful surgery for primary hyperparathyroidism: no additive effect from vitamin D supplementation: results of a double-blind randomized study.

Åberg V, Norenstedt S, Zedenius J, Sääf M, Nordenström J, Pernow Y, Nilsson IL.

Eur J Endocrinol. 2015 Feb;172(2):181-7. doi: 10.1530/EJE-14-0757. Epub 2014 Nov 20.


Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy.

Volpe C, Hamberger B, Höög A, Mukai K, Calissendorff J, Wahrenberg H, Zedenius J, Thorén M.

Clin Endocrinol (Oxf). 2015 May;82(5):639-47. doi: 10.1111/cen.12645. Epub 2014 Dec 19.


Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

Wennerberg E, Pfefferle A, Ekblad L, Yoshimoto Y, Kremer V, Kaminskyy VO, Juhlin CC, Höög A, Bodin I, Svjatoha V, Larsson C, Zedenius J, Wennerberg J, Lundqvist A.

Clin Cancer Res. 2014 Nov 15;20(22):5733-44. doi: 10.1158/1078-0432.CCR-14-0291. Epub 2014 Sep 11.


TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA.

Wang N, Liu T, Sofiadis A, Juhlin CC, Zedenius J, Höög A, Larsson C, Xu D.

Cancer. 2014 Oct 1;120(19):2965-79. doi: 10.1002/cncr.28800. Epub 2014 Jun 4.


Functional role of the Ca²⁺-activated Cl⁻ channel DOG1/TMEM16A in gastrointestinal stromal tumor cells.

Berglund E, Akcakaya P, Berglund D, Karlsson F, Vukojević V, Lee L, Bogdanović D, Lui WO, Larsson C, Zedenius J, Fröbom R, Bränström R.

Exp Cell Res. 2014 Aug 15;326(2):315-25. doi: 10.1016/j.yexcr.2014.05.003. Epub 2014 May 10.


Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors: an in vivo and in vitro study.

Fotouhi O, Adel Fahmideh M, Kjellman M, Sulaiman L, Höög A, Zedenius J, Hashemi J, Larsson C.

Epigenetics. 2014 Jul;9(7):987-97. doi: 10.4161/epi.28936. Epub 2014 Apr 24.


Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.

Wang N, Xu D, Sofiadis A, Höög A, Vukojević V, Bäckdahl M, Zedenius J, Larsson C.

J Clin Endocrinol Metab. 2014 Aug;99(8):E1571-9. doi: 10.1210/jc.2014-1158. Epub 2014 Apr 23.


MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas.

Velázquez-Fernández D, Caramuta S, Özata DM, Lu M, Höög A, Bäckdahl M, Larsson C, Lui WO, Zedenius J.

Eur J Endocrinol. 2014 Mar 8;170(4):583-91. doi: 10.1530/EJE-13-0817. Print 2014 Apr.


Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells.

Berglund E, Ubhayasekera SJ, Karlsson F, Akcakaya P, Aluthgedara W, Ahlen J, Fröbom R, Nilsson IL, Lui WO, Larsson C, Zedenius J, Bergquist J, Bränström R.

Anticancer Drugs. 2014 Apr;25(4):415-22. doi: 10.1097/CAD.0000000000000069.


Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization.

Hashemi J, Fotouhi O, Sulaiman L, Kjellman M, Höög A, Zedenius J, Larsson C.

BMC Cancer. 2013 Oct 29;13:505. doi: 10.1186/1471-2407-13-505.


The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas.

Liu T, Wang N, Cao J, Sofiadis A, Dinets A, Zedenius J, Larsson C, Xu D.

Oncogene. 2014 Oct 16;33(42):4978-84. doi: 10.1038/onc.2013.446. Epub 2013 Oct 21.


Vitamin D supplementation after parathyroidectomy: effect on bone mineral density-a randomized double-blind study.

Norenstedt S, Pernow Y, Zedenius J, Nordenström J, Sääf M, Granath F, Nilsson IL.

J Bone Miner Res. 2014 Apr;29(4):960-7. doi: 10.1002/jbmr.2102.


Outcome after resection and radiofrequency ablation of liver metastases from small intestinal neuroendocrine tumours.

Norlén O, Stålberg P, Zedenius J, Hellman P.

Br J Surg. 2013 Oct;100(11):1505-14. doi: 10.1002/bjs.9262.


Primary hyperparathyroidism and metabolic risk factors, impact of parathyroidectomy and vitamin D supplementation, and results of a randomized double-blind study.

Norenstedt S, Pernow Y, Brismar K, Sääf M, Ekip A, Granath F, Zedenius J, Nilsson IL.

Eur J Endocrinol. 2013 Oct 21;169(6):795-804. doi: 10.1530/EJE-13-0547. Print 2013 Dec.


Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.

Caramuta S, Lee L, Ozata DM, Akçakaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO.

Endocr Relat Cancer. 2013 Jul 4;20(4):551-64. doi: 10.1530/ERC-13-0098. Print 2013 Aug.


Evidence for Ca(2+)-regulated ATP release in gastrointestinal stromal tumors.

Berglund E, Berglund D, Akcakaya P, Ghaderi M, Daré E, Berggren PO, Köhler M, Aspinwall CA, Lui WO, Zedenius J, Larsson C, Bränström R.

Exp Cell Res. 2013 May 1;319(8):1229-38. doi: 10.1016/j.yexcr.2013.03.001. Epub 2013 Mar 13.


Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter.

Åkerström T, Crona J, Delgado Verdugo A, Starker LF, Cupisti K, Willenberg HS, Knoefel WT, Saeger W, Feller A, Ip J, Soon P, Anlauf M, Alesina PF, Schmid KW, Decaussin M, Levillain P, Wängberg B, Peix JL, Robinson B, Zedenius J, Bäckdahl M, Caramuta S, Iwen KA, Botling J, Stålberg P, Kraimps JL, Dralle H, Hellman P, Sidhu S, Westin G, Lehnert H, Walz MK, Åkerström G, Carling T, Choi M, Lifton RP, Björklund P.

PLoS One. 2012;7(7):e41926. doi: 10.1371/journal.pone.0041926. Epub 2012 Jul 27.


Anaplastic carcinoma of the thyroid gland: treatment and outcome over 13 years at one institution.

Segerhammar I, Larsson C, Nilsson IL, Bäckdahl M, Höög A, Wallin G, Foukakis T, Zedenius J.

J Surg Oncol. 2012 Dec;106(8):981-6. doi: 10.1002/jso.23177. Epub 2012 Jun 4.


Clinical, genetic, and immunohistochemical characterization of 70 Ukrainian adult cases with post-Chornobyl papillary thyroid carcinoma.

Dinets A, Hulchiy M, Sofiadis A, Ghaderi M, Höög A, Larsson C, Zedenius J.

Eur J Endocrinol. 2012 Jun;166(6):1049-60. doi: 10.1530/EJE-12-0144. Epub 2012 Mar 28.


Proteomic profiling of follicular and papillary thyroid tumors.

Sofiadis A, Becker S, Hellman U, Hultin-Rosenberg L, Dinets A, Hulchiy M, Zedenius J, Wallin G, Foukakis T, Höög A, Auer G, Lehtiö J, Larsson C.

Eur J Endocrinol. 2012 Apr;166(4):657-67. doi: 10.1530/EJE-11-0856. Epub 2012 Jan 24.


Thyroid incidentaloma detected by fluorodeoxyglucose positron emission tomography/computed tomography: practical management algorithm.

Nilsson IL, Arnberg F, Zedenius J, Sundin A.

World J Surg. 2011 Dec;35(12):2691-7. doi: 10.1007/s00268-011-1291-4.


The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma.

Özata DM, Caramuta S, Velázquez-Fernández D, Akçakaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO.

Endocr Relat Cancer. 2011 Oct 27;18(6):643-55. doi: 10.1530/ERC-11-0082. Print 2011 Oct.


Breast cancer associated with primary hyperparathyroidism: a nested case control study.

Norenstedt S, Granath F, Ekbom A, Bergh J, Lambe M, Adolfsson J, Warnberg F, Zedenius J, Nilsson IL.

Clin Epidemiol. 2011 Mar 25;3:103-6. doi: 10.2147/CLEP.S17298.


Proteomic study of thyroid tumors reveals frequent up-regulation of the Ca2+ -binding protein S100A6 in papillary thyroid carcinoma.

Sofiadis A, Dinets A, Orre LM, Branca RM, Juhlin CC, Foukakis T, Wallin G, Höög A, Hulchiy M, Zedenius J, Larsson C, Lehtiö J.

Thyroid. 2010 Oct;20(10):1067-76. doi: 10.1089/thy.2009.0400.


[Antithyroid drug-induced agranulocytosis. A rare but dreaded condition].

Lehtihet M, Zedenius J, Helldén A, Axelsson R, Calissendorff J.

Lakartidningen. 2009 Oct 7-13;106(41):2607-8, 2610-1. Review. Swedish. No abstract available.


Diagnosis and prognosis of iatrogenic injury of the recurrent laryngeal nerve.

Hydman J, Björck G, Persson JK, Zedenius J, Mattsson P.

Ann Otol Rhinol Laryngol. 2009 Jul;118(7):506-11.


Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy.

Sofiadis A, Tani E, Foukakis T, Kjellman P, Skoog L, Höög A, Wallin G, Zedenius J, Larsson C.

Int J Oncol. 2009 Aug;35(2):369-74.


Postoperative mortality in parathyroid surgery in Sweden during five decades: improved outcome despite older patients.

Norenstedt S, Ekbom A, Brandt L, Zedenius J, Nilsson IL.

Eur J Endocrinol. 2009 Feb;160(2):295-9. doi: 10.1530/EJE-08-0523. Epub 2008 Nov 28.


Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer.

Lee JJ, Geli J, Larsson C, Wallin G, Karimi M, Zedenius J, Höög A, Foukakis T.

Int J Oncol. 2008 Oct;33(4):861-9.


Is somatic RET mutation a prognostic factor for sporadic medullary thyroid carcinoma?

Zedenius J.

Nat Clin Pract Endocrinol Metab. 2008 Aug;4(8):432-3. doi: 10.1038/ncpendmet0866. Epub 2008 Jun 10. No abstract available.


Fine-needle aspiration biopsy of benign thyroid nodules: an evidence-based review.

Lundgren CI, Zedenius J, Skoog L.

World J Surg. 2008 Jul;32(7):1247-52. doi: 10.1007/s00268-008-9578-9. Review.


Novel therapeutic strategies for neuroendocrine tumours--can eminence replace evidence?

Zedenius J.

Acta Oncol. 2008;47(1):3-4. No abstract available.


A PCR-based expression signature of malignancy in follicular thyroid tumors.

Foukakis T, Gusnanto A, Au AY, Höög A, Lui WO, Larsson C, Wallin G, Zedenius J.

Endocr Relat Cancer. 2007 Jun;14(2):381-91.

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