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Items: 1 to 50 of 56

1.

Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities.

Unterhauser K, Pöltl L, Schneditz G, Kienesberger S, Glabonjat RA, Kitsera M, Pletz J, Josa-Prado F, Dornisch E, Lembacher-Fadum C, Roier S, Gorkiewicz G, Lucena D, Barasoain I, Kroutil W, Wiedner M, Loizou JI, Breinbauer R, Díaz JF, Schild S, Högenauer C, Zechner EL.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3774-3783. doi: 10.1073/pnas.1819154116. Epub 2019 Feb 11.

2.

Fic Proteins of Campylobacter fetus subsp. venerealis Form a Network of Functional Toxin-Antitoxin Systems.

Sprenger H, Kienesberger S, Pertschy B, Pöltl L, Konrad B, Bhutada P, Vorkapic D, Atzmüller D, Feist F, Högenauer C, Gorkiewicz G, Zechner EL.

Front Microbiol. 2017 Oct 17;8:1965. doi: 10.3389/fmicb.2017.01965. eCollection 2017.

3.

Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline.

Dornisch E, Pletz J, Glabonjat RA, Martin F, Lembacher-Fadum C, Neger M, Högenauer C, Francesconi K, Kroutil W, Zangger K, Breinbauer R, Zechner EL.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14753-14757. doi: 10.1002/anie.201707737. Epub 2017 Oct 18.

4.

Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation.

Ilangovan A, Kay CWM, Roier S, El Mkami H, Salvadori E, Zechner EL, Zanetti G, Waksman G.

Cell. 2017 May 4;169(4):708-721.e12. doi: 10.1016/j.cell.2017.04.010. Epub 2017 Apr 27.

5.

Inflammatory disease caused by intestinal pathobionts.

Zechner EL.

Curr Opin Microbiol. 2017 Feb;35:64-69. doi: 10.1016/j.mib.2017.01.011. Epub 2017 Feb 10. Review.

6.

Relaxases and Plasmid Transfer in Gram-Negative Bacteria.

Zechner EL, Moncalián G, de la Cruz F.

Curr Top Microbiol Immunol. 2017;413:93-113. doi: 10.1007/978-3-319-75241-9_4. Review.

PMID:
29536356
7.

Conjugative DNA Transfer Is Enhanced by Plasmid R1 Partitioning Proteins.

Gruber CJ, Lang S, Rajendra VK, Nuk M, Raffl S, Schildbach JF, Zechner EL.

Front Mol Biosci. 2016 Jul 19;3:32. doi: 10.3389/fmolb.2016.00032. eCollection 2016.

8.

Gastric Helicobacter pylori Infection Affects Local and Distant Microbial Populations and Host Responses.

Kienesberger S, Cox LM, Livanos A, Zhang XS, Chung J, Perez-Perez GI, Gorkiewicz G, Zechner EL, Blaser MJ.

Cell Rep. 2016 Feb 16;14(6):1395-1407. doi: 10.1016/j.celrep.2016.01.017. Epub 2016 Feb 4.

9.

TrhR, TrhY and HtdA, a novel regulatory circuit that modulates conjugation of the IncHI plasmids.

Gibert M, Juárez A, Zechner EL, Madrid C, Balsalobre C.

Mol Microbiol. 2014 Oct 10. doi: 10.1111/mmi.12823. [Epub ahead of print]

10.

Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis.

Schneditz G, Rentner J, Roier S, Pletz J, Herzog KA, Bücker R, Troeger H, Schild S, Weber H, Breinbauer R, Gorkiewicz G, Högenauer C, Zechner EL.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13181-6. doi: 10.1073/pnas.1403274111. Epub 2014 Aug 25.

11.

Common requirement for the relaxosome of plasmid R1 in multiple activities of the conjugative type IV secretion system.

Lang S, Gruber CJ, Raffl S, Reisner A, Zechner EL.

J Bacteriol. 2014 Jun;196(11):2108-21. doi: 10.1128/JB.00045-13. Epub 2014 Mar 28.

12.

Genotypes of Klebsiella oxytoca isolates from patients with nosocomial pneumonia are distinct from those of isolates from patients with antibiotic-associated hemorrhagic colitis.

Herzog KA, Schneditz G, Leitner E, Feierl G, Hoffmann KM, Zollner-Schwetz I, Krause R, Gorkiewicz G, Zechner EL, Högenauer C.

J Clin Microbiol. 2014 May;52(5):1607-16. doi: 10.1128/JCM.03373-13. Epub 2014 Mar 5.

13.

Comparative genome analysis of Campylobacter fetus subspecies revealed horizontally acquired genetic elements important for virulence and niche specificity.

Kienesberger S, Sprenger H, Wolfgruber S, Halwachs B, Thallinger GG, Perez-Perez GI, Blaser MJ, Zechner EL, Gorkiewicz G.

PLoS One. 2014 Jan 9;9(1):e85491. doi: 10.1371/journal.pone.0085491. eCollection 2014.

14.

Type 1 fimbriae contribute to catheter-associated urinary tract infections caused by Escherichia coli.

Reisner A, Maierl M, Jörger M, Krause R, Berger D, Haid A, Tesic D, Zechner EL.

J Bacteriol. 2014 Mar;196(5):931-9. doi: 10.1128/JB.00985-13. Epub 2013 Dec 13.

15.

A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative type IV secretion system.

Alperi A, Larrea D, Fernández-González E, Dehio C, Zechner EL, Llosa M.

J Bacteriol. 2013 Nov;195(22):4999-5006. doi: 10.1128/JB.00367-13. Epub 2013 Aug 30.

16.

Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems.

Redzej A, Ilangovan A, Lang S, Gruber CJ, Topf M, Zangger K, Zechner EL, Waksman G.

Mol Microbiol. 2013 Jul;89(2):324-33. doi: 10.1111/mmi.12275. Epub 2013 Jun 14.

17.

Assembly and mechanisms of bacterial type IV secretion machines.

Zechner EL, Lang S, Schildbach JF.

Philos Trans R Soc Lond B Biol Sci. 2012 Apr 19;367(1592):1073-87. doi: 10.1098/rstb.2011.0207. Review.

18.

So close and yet so far - Molecular Microbiology of Campylobacter fetus subspecies.

Sprenger H, Zechner EL, Gorkiewicz G.

Eur J Microbiol Immunol (Bp). 2012 Mar;2(1):66-75. doi: 10.1556/EuJMI.2.2012.1.10. Epub 2012 Mar 17. Review.

19.

In situ monitoring of IncF plasmid transfer on semi-solid agar surfaces reveals a limited invasion of plasmids in recipient colonies.

Reisner A, Wolinski H, Zechner EL.

Plasmid. 2012 Mar;67(2):155-61. doi: 10.1016/j.plasmid.2012.01.001. Epub 2012 Jan 10.

20.

General requirements for protein secretion by the F-like conjugation system R1.

Lang S, Zechner EL.

Plasmid. 2012 Mar;67(2):128-38. doi: 10.1016/j.plasmid.2011.12.014. Epub 2012 Jan 10.

21.

An activation domain of plasmid R1 TraI protein delineates stages of gene transfer initiation.

Lang S, Kirchberger PC, Gruber CJ, Redzej A, Raffl S, Zellnig G, Zangger K, Zechner EL.

Mol Microbiol. 2011 Dec;82(5):1071-85. doi: 10.1111/j.1365-2958.2011.07872.x. Epub 2011 Nov 8.

22.

New molecular microbiology approaches in the study of Campylobacter fetus.

Kienesberger S, Gorkiewicz G, Wolinski H, Zechner EL.

Microb Biotechnol. 2011 Jan;4(1):8-19. doi: 10.1111/j.1751-7915.2010.00173.x. Review.

23.

The transfer operon of plasmid R1 extends beyond finO into the downstream replication genes.

Nuk MR, Reisner A, Zechner EL.

Plasmid. 2011 Mar;65(2):150-8. doi: 10.1016/j.plasmid.2010.12.003. Epub 2010 Dec 8.

PMID:
21145348
24.

Functional analysis of the finO distal region of plasmid R1.

Nuk MR, Reisner A, Neuwirth M, Schilcher K, Arnold R, Jehl A, Rattei T, Zechner EL.

Plasmid. 2011 Mar;65(2):159-68. doi: 10.1016/j.plasmid.2010.12.002. Epub 2010 Dec 8.

PMID:
21145347
25.

Molecular recognition determinants for type IV secretion of diverse families of conjugative relaxases.

Lang S, Gruber K, Mihajlovic S, Arnold R, Gruber CJ, Steinlechner S, Jehl MA, Rattei T, Fröhlich KU, Zechner EL.

Mol Microbiol. 2010 Dec;78(6):1539-55. doi: 10.1111/j.1365-2958.2010.07423.x. Epub 2010 Oct 15.

26.

Interbacterial macromolecular transfer by the Campylobacter fetus subsp. venerealis type IV secretion system.

Kienesberger S, Schober Trummler C, Fauster A, Lang S, Sprenger H, Gorkiewicz G, Zechner EL.

J Bacteriol. 2011 Feb;193(3):744-58. doi: 10.1128/JB.00798-10. Epub 2010 Nov 29.

27.

Cytotoxic effects of Klebsiella oxytoca strains isolated from patients with antibiotic-associated hemorrhagic colitis or other diseases caused by infections and from healthy subjects.

Joainig MM, Gorkiewicz G, Leitner E, Weberhofer P, Zollner-Schwetz I, Lippe I, Feierl G, Krause R, Hinterleitner T, Zechner EL, Högenauer C.

J Clin Microbiol. 2010 Mar;48(3):817-24. doi: 10.1128/JCM.01741-09. Epub 2010 Jan 6.

28.

Conjugative DNA metabolism in Gram-negative bacteria.

de la Cruz F, Frost LS, Meyer RJ, Zechner EL.

FEMS Microbiol Rev. 2010 Jan;34(1):18-40. doi: 10.1111/j.1574-6976.2009.00195.x.

29.

A genomic island defines subspecies-specific virulence features of the host-adapted pathogen Campylobacter fetus subsp. venerealis.

Gorkiewicz G, Kienesberger S, Schober C, Scheicher SR, Gülly C, Zechner R, Zechner EL.

J Bacteriol. 2010 Jan;192(2):502-17. doi: 10.1128/JB.00803-09. Epub 2009 Nov 6.

30.

Protein and DNA effectors control the TraI conjugative helicase of plasmid R1.

Sut MV, Mihajlovic S, Lang S, Gruber CJ, Zechner EL.

J Bacteriol. 2009 Nov;191(22):6888-99. doi: 10.1128/JB.00920-09. Epub 2009 Sep 18.

31.

Plasmid r1 conjugative DNA processing is regulated at the coupling protein interface.

Mihajlovic S, Lang S, Sut MV, Strohmaier H, Gruber CJ, Koraimann G, Cabezón E, Moncalián G, de la Cruz F, Zechner EL.

J Bacteriol. 2009 Nov;191(22):6877-87. doi: 10.1128/JB.00918-09. Epub 2009 Sep 18.

32.

Development of experimental genetic tools for Campylobacter fetus.

Kienesberger S, Gorkiewicz G, Joainig MM, Scheicher SR, Leitner E, Zechner EL.

Appl Environ Microbiol. 2007 Jul;73(14):4619-30. Epub 2007 May 18.

33.

General mutagenesis of F plasmid TraI reveals its role in conjugative regulation.

Haft RJ, Palacios G, Nguyen T, Mally M, Gachelet EG, Zechner EL, Traxler B.

J Bacteriol. 2006 Sep;188(17):6346-53.

34.

Synergistic effects in mixed Escherichia coli biofilms: conjugative plasmid transfer drives biofilm expansion.

Reisner A, Höller BM, Molin S, Zechner EL.

J Bacteriol. 2006 May;188(10):3582-8.

35.

In vitro biofilm formation of commensal and pathogenic Escherichia coli strains: impact of environmental and genetic factors.

Reisner A, Krogfelt KA, Klein BM, Zechner EL, Molin S.

J Bacteriol. 2006 May;188(10):3572-81.

36.

Unsaturated fatty acids are inhibitors of bacterial conjugation.

Fernandez-Lopez R, Machón C, Longshaw CM, Martin S, Molin S, Zechner EL, Espinosa M, Lanka E, de la Cruz F.

Microbiology. 2005 Nov;151(Pt 11):3517-26.

PMID:
16272375
37.

Concomitant reconstitution of TraI-catalyzed DNA transesterase and DNA helicase activity in vitro.

Csitkovits VC, Dermić D, Zechner EL.

J Biol Chem. 2004 Oct 29;279(44):45477-84. Epub 2004 Aug 17.

38.

The Horizontal Gene Pool: an ESF workshop summary.

Zechner EL, Bailey MJ.

Plasmid. 2004 Mar;51(2):67-74.

PMID:
15068024
39.

Extent of single-stranded DNA required for efficient TraI helicase activity in vitro.

Csitkovits VC, Zechner EL.

J Biol Chem. 2003 Dec 5;278(49):48696-703. Epub 2003 Sep 23.

40.

Species-specific identification of campylobacters by partial 16S rRNA gene sequencing.

Gorkiewicz G, Feierl G, Schober C, Dieber F, Köfer J, Zechner R, Zechner EL.

J Clin Microbiol. 2003 Jun;41(6):2537-46.

41.

Development and maturation of Escherichia coli K-12 biofilms.

Reisner A, Haagensen JA, Schembri MA, Zechner EL, Molin S.

Mol Microbiol. 2003 May;48(4):933-46.

42.

Recombinogenic engineering of conjugative plasmids with fluorescent marker cassettes.

Reisner A, Molin S, Zechner EL.

FEMS Microbiol Ecol. 2002 Nov 1;42(2):251-9. doi: 10.1111/j.1574-6941.2002.tb01015.x.

43.

Transmission of Campylobacter hyointestinalis from a pig to a human.

Gorkiewicz G, Feierl G, Zechner R, Zechner EL.

J Clin Microbiol. 2002 Jul;40(7):2601-5.

44.

TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates?

Schröder G, Krause S, Zechner EL, Traxler B, Yeo HJ, Lurz R, Waksman G, Lanka E.

J Bacteriol. 2002 May;184(10):2767-79.

45.

Transfer protein TraY of plasmid R1 stimulates TraI-catalyzed oriT cleavage in vivo.

Karl W, Bamberger M, Zechner EL.

J Bacteriol. 2001 Feb;183(3):909-14.

46.

In vivo definition of the functional origin of leading strand replication on the lactococcal plasmid pFX2.

Grohmann E, Moscoso M, Zechner EL, del Solar G, Espinosa M.

Mol Gen Genet. 1998 Oct;260(1):38-47.

PMID:
9829826
47.

Signal transduction and bacterial conjugation: characterization of the role of ArcA in regulating conjugative transfer of the resistance plasmid R1.

Strohmaier H, Noiges R, Kotschan S, Sawers G, Högenauer G, Zechner EL, Koraimann G.

J Mol Biol. 1998 Mar 27;277(2):309-16.

PMID:
9514749
48.

Transfer protein TraM stimulates TraI-catalyzed cleavage of the transfer origin of plasmid R1 in vivo.

Kupelwieser G, Schwab M, Högenauer G, Koraimann G, Zechner EL.

J Mol Biol. 1998 Jan 9;275(1):81-94.

PMID:
9451441
49.

TraM of plasmid R1 controls transfer gene expression as an integrated control element in a complex regulatory network.

Pölzleitner E, Zechner EL, Renner W, Fratte R, Jauk B, Högenauer G, Koraimann G.

Mol Microbiol. 1997 Aug;25(3):495-507.

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