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Items: 26

1.

Metabolism of loratadine and further characterization of its in vitro metabolites.

Ghosal A, Gupta S, Ramanathan R, Yuan Y, Lu X, Su AD, Alvarez N, Zbaida S, Chowdhury SK, Alton KB.

Drug Metab Lett. 2009 Aug;3(3):162-70. Epub 2009 Aug 1.

PMID:
19702548
2.

Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar).

Ghosal A, Chowdhury SK, Tong W, Hapangama N, Yuan Y, Su AD, Zbaida S.

Drug Metab Dispos. 2006 Apr;34(4):628-35. Epub 2006 Jan 27.

PMID:
16443667
3.

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 351125, a CCR5 antagonist.

Ghosal A, Chowdhury SK, Gupta S, Yuan Y, Iannucci R, Zhang H, Zbaida S, Patrick JE, Alton KB.

Xenobiotica. 2005 May;35(5):405-17.

PMID:
16012074
4.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine.

Ghosal A, Yuan Y, Hapangama N, Su AD, Alvarez N, Chowdhury SK, Alton KB, Patrick JE, Zbaida S.

Biopharm Drug Dispos. 2004 Sep;25(6):243-52.

PMID:
15334623
5.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.

Drug Metab Dispos. 2004 Mar;32(3):314-20.

PMID:
14977865
6.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.

Drug Metab Dispos. 2004 Feb;32(2):267-71.

PMID:
14744950
7.

Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes.

Ghosal A, Hapangama N, Yuan Y, Lu X, Horne D, Patrick JE, Zbaida S.

Biopharm Drug Dispos. 2003 Dec;24(9):375-84.

PMID:
14689466
8.

In vitro uptake of SCH 27899 (evernimicin) by rat alveolar macrophages.

Zbaida S, Brieland J, Krieter P, Loebenberg D, Krishna G, Horne D, Lu X, Yuan Y, Hare R, Cayen MN, Patrick JE.

Antimicrob Agents Chemother. 2001 Mar;45(3):959-61.

9.

In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)- one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites.

Zbaida S, Du Y, Shannon D, Laudicina D, Thonoor CM, Ng K, Blumenkrantz N, Patrick JE, Cayen MN, Friary R, Seidl V, Chan TM, Pramanik B, Spangler M, McPhail AT.

Biopharm Drug Dispos. 1998 Jul;19(5):315-32.

PMID:
9673784
11.
12.

Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors.

Zbaida S, Brewer CF, Levine WG.

Drug Metab Dispos. 1992 Nov-Dec;20(6):902-8.

PMID:
1362944
13.

Multiple mechanisms in hepatic microsomal azoreduction.

Levine WG, Stoddart A, Zbaida S.

Xenobiotica. 1992 Sep-Oct;22(9-10):1111-20.

PMID:
1441602
14.

Role of electronic factors in binding and reduction of azo dyes by hepatic microsomes.

Zbaida S, Levine WG.

J Pharmacol Exp Ther. 1992 Feb;260(2):554-61.

PMID:
1738106
15.
16.

Two classes of azo dye reductase activity associated with rat liver microsomal cytochrome P-450.

Levine WG, Zbaida S.

Adv Exp Med Biol. 1991;283:315-21. No abstract available.

PMID:
1906222
17.
19.

Biomimetic models for monooxygenases.

Zbaida S, Kariv R.

Biopharm Drug Dispos. 1989 Sep-Oct;10(5):431-42. Review.

PMID:
2679901
20.

Studies on the mechanism of reduction of azo dye carcinogens by rat liver microsomal cytochrome P-450.

Zbaida S, Stoddart AM, Levine WG.

Chem Biol Interact. 1989;69(1):61-71.

PMID:
2914330
22.
23.

Reactions of theophylline, theobromine and caffeine with Fenton's reagent--simulation of hepatic metabolism.

Zbaida S, Kariv R, Fischer P, Gilhar D.

Xenobiotica. 1987 May;17(5):617-21.

PMID:
3604265
24.

Reaction of cimetidine with Fenton reagent. A biomimetic model for the mixed-function oxidase drug metabolism.

Zbaida S, Kariv R, Fischer P, Silman-Greenspan J, Tashma Z.

Eur J Biochem. 1986 Feb 3;154(3):603-5.

25.

Replacing the Mixed Function Oxidase N-Demethylation by Hydrogen Peroxide and either Hemoglobin or Ferrous Sulfate.

Zbaida S, Gilhar D, Silman-Greenspan J.

Pharm Res. 1984 Nov;1(6):277-9. doi: 10.1023/A:1016354220779.

PMID:
24277364
26.

In vitro studies on the metabolism of cimetidine by rat liver microsomes--identification of a new N-desmethylcimetidine metabolite.

Zbaida S, Silman-Greenspan J, Yosselson-Superstine S, Merin E.

Biopharm Drug Dispos. 1984 Oct-Dec;5(4):415-9. No abstract available.

PMID:
6525447

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