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Items: 1 to 50 of 62

1.

Cell communication and signaling: how to turn bad language into positive one.

Chiodoni C, Di Martino MT, Zazzeroni F, Caraglia M, Donadelli M, Meschini S, Leonetti C, Scotlandi K.

J Exp Clin Cancer Res. 2019 Mar 13;38(1):128. doi: 10.1186/s13046-019-1122-2.

2.

Turning an old GADDget into a troublemaker.

Capece D, D'Andrea D, Verzella D, Tornatore L, Begalli F, Bennett J, Zazzeroni F, Franzoso G.

Cell Death Differ. 2018 Mar;25(4):640-642. doi: 10.1038/s41418-018-0087-6. Epub 2018 Mar 6. No abstract available.

3.

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy.

Di Martino MT, Zazzeroni F, Donadelli M, Chiodoni C, Caraglia M, Scotlandi K, Meschini S, Leonetti C.

J Exp Clin Cancer Res. 2018 Mar 5;37(1):48. doi: 10.1186/s13046-018-0710-x. No abstract available.

4.

KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.

Tessitore A, Bruera G, Mastroiaco V, Cannita K, Cortellini A, Cocciolone V, Dal Mas A, Calvisi G, Zazzeroni F, Ficorella C, Ricevuto E, Alesse E.

Hum Pathol. 2018 Apr;74:178-182. doi: 10.1016/j.humpath.2018.01.021. Epub 2018 Jan 31.

PMID:
29409955
5.

GADD45β Loss Ablates Innate Immunosuppression in Cancer.

Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, Forbes SJ, Sica A, Alesse E, Zazzeroni F, Franzoso G.

Cancer Res. 2018 Mar 1;78(5):1275-1292. doi: 10.1158/0008-5472.CAN-17-1833. Epub 2017 Dec 26.

6.

Next-generation sequencing: recent applications to the analysis of colorectal cancer.

Del Vecchio F, Mastroiaco V, Di Marco A, Compagnoni C, Capece D, Zazzeroni F, Capalbo C, Alesse E, Tessitore A.

J Transl Med. 2017 Dec 8;15(1):246. doi: 10.1186/s12967-017-1353-y. Review.

7.

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model.

Tessitore A, Mastroiaco V, Vetuschi A, Sferra R, Pompili S, Cicciarelli G, Barnabei R, Capece D, Zazzeroni F, Capalbo C, Alesse E.

Oncotarget. 2017 Jun 21;8(32):53482-53494. doi: 10.18632/oncotarget.18585. eCollection 2017 Aug 8.

8.

Cancer secretome and inflammation: The bright and the dark sides of NF-κB.

Capece D, Verzella D, Tessitore A, Alesse E, Capalbo C, Zazzeroni F.

Semin Cell Dev Biol. 2018 Jun;78:51-61. doi: 10.1016/j.semcdb.2017.08.004. Epub 2017 Aug 2. Review.

9.

Adipose-derived stem cells sustain prolonged angiogenesis through leptin secretion.

Delle Monache S, Calgani A, Sanità P, Zazzeroni F, Gentile Warschauer E, Giuliani A, Amicucci G, Angelucci A.

Growth Factors. 2016 Aug;34(3-4):87-96. doi: 10.1080/08977194.2016.1191481. Epub 2016 Jun 30.

PMID:
27362575
10.

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

Cipriani P, Di Benedetto P, Ruscitti P, Liakouli V, Berardicurti O, Carubbi F, Ciccia F, Guggino G, Zazzeroni F, Alesse E, Triolo G, Giacomelli R.

J Rheumatol. 2016 Jul;43(7):1340-9. doi: 10.3899/jrheum.150996. Epub 2016 Jun 1.

PMID:
27252423
11.

MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice.

Tessitore A, Cicciarelli G, Del Vecchio F, Gaggiano A, Verzella D, Fischietti M, Mastroiaco V, Vetuschi A, Sferra R, Barnabei R, Capece D, Zazzeroni F, Alesse E.

BMC Cancer. 2016 Jan 5;16:3. doi: 10.1186/s12885-015-2007-1.

12.

Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model.

Del Vecchio F, Gallo F, Di Marco A, Mastroiaco V, Caianiello P, Zazzeroni F, Alesse E, Tessitore A.

BMC Bioinformatics. 2015 Dec 10;16:408. doi: 10.1186/s12859-015-0836-1.

13.

Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.

Cipriani P, Di Benedetto P, Ruscitti P, Verzella D, Fischietti M, Zazzeroni F, Liakouli V, Carubbi F, Berardicurti O, Alesse E, Giacomelli R.

Arthritis Res Ther. 2015 Sep 10;17:247. doi: 10.1186/s13075-015-0754-7.

14.

Targeting the NF-κB pathway in prostate cancer: a promising therapeutic approach?

Verzella D, Fischietti M, Capece D, Vecchiotti D, Del Vecchio F, Cicciarelli G, Mastroiaco V, Tessitore A, Alesse E, Zazzeroni F.

Curr Drug Targets. 2016;17(3):311-20.

PMID:
26343112
15.

Therapeutic Use of MicroRNAs in Cancer.

Tessitore A, Cicciarelli G, Mastroiaco V, Vecchio FD, Capece D, Verzella D, Fischietti M, Vecchiotti D, Zazzeroni F, Alesse E.

Anticancer Agents Med Chem. 2016;16(1):7-19. Review.

PMID:
26299662
16.

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist.

Cipriani P, Di Benedetto P, Ruscitti P, Capece D, Zazzeroni F, Liakouli V, Pantano I, Berardicurti O, Carubbi F, Pecetti G, Turricchia S, Alesse E, Iglarz M, Giacomelli R.

J Rheumatol. 2015 Oct;42(10):1808-16. doi: 10.3899/jrheum.150088. Epub 2015 Aug 15.

PMID:
26276964
17.

The role of IL-1β in the bone loss during rheumatic diseases.

Ruscitti P, Cipriani P, Carubbi F, Liakouli V, Zazzeroni F, Di Benedetto P, Berardicurti O, Alesse E, Giacomelli R.

Mediators Inflamm. 2015;2015:782382. doi: 10.1155/2015/782382. Epub 2015 Apr 12. Review.

18.

Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis.

Cipriani P, Di Benedetto P, Capece D, Zazzeroni F, Liakouli V, Ruscitti P, Pantano I, Berardicurti O, Carubbi F, Alesse E, Giacomelli R.

Fibrogenesis Tissue Repair. 2014 Sep 15;7:13. doi: 10.1186/1755-1536-7-13. eCollection 2014.

19.

KCTD11 tumor suppressor gene expression is reduced in prostate adenocarcinoma.

Zazzeroni F, Nicosia D, Tessitore A, Gallo R, Verzella D, Fischietti M, Vecchiotti D, Ventura L, Capece D, Gulino A, Alesse E.

Biomed Res Int. 2014;2014:380398. doi: 10.1155/2014/380398. Epub 2014 Jun 19.

20.

MicroRNAs in the DNA Damage/Repair Network and Cancer.

Tessitore A, Cicciarelli G, Del Vecchio F, Gaggiano A, Verzella D, Fischietti M, Vecchiotti D, Capece D, Zazzeroni F, Alesse E.

Int J Genomics. 2014;2014:820248. doi: 10.1155/2014/820248. Epub 2014 Jan 30. Review.

21.

A novel, non-canonical splice variant of the Ikaros gene is aberrantly expressed in B-cell lymphoproliferative disorders.

Capece D, Zazzeroni F, Mancarelli MM, Verzella D, Fischietti M, Di Tommaso A, Maccarone R, Plebani S, Di Ianni M, Gulino A, Alesse E.

PLoS One. 2013 Jul 9;8(7):e68080. doi: 10.1371/journal.pone.0068080. Print 2013.

22.

Reverse-phase protein microarray highlights HER2 signaling activation in immunohistochemistry/FISH/HER2-negative breast cancers.

Tessitore A, Zazzeroni F, Alesse E.

Expert Rev Proteomics. 2013 Jun;10(3):223-6. doi: 10.1586/epr.13.18.

PMID:
23777213
23.

Inhibition of ErbB receptors, Hedgehog and NF-kappaB signaling by polyphenols in cancer.

Benvenuto M, Fantini M, Masuelli L, De Smaele E, Zazzeroni F, Tresoldi I, Calabrese G, Galvano F, Modesti A, Bei R.

Front Biosci (Landmark Ed). 2013 Jun 1;18:1290-310. Review.

PMID:
23747884
24.

The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages.

Capece D, Fischietti M, Verzella D, Gaggiano A, Cicciarelli G, Tessitore A, Zazzeroni F, Alesse E.

Biomed Res Int. 2013;2013:187204. doi: 10.1155/2013/187204. Epub 2012 Dec 30. Review.

25.

Serum biomarkers identification by mass spectrometry in high-mortality tumors.

Tessitore A, Gaggiano A, Cicciarelli G, Verzella D, Capece D, Fischietti M, Zazzeroni F, Alesse E.

Int J Proteomics. 2013;2013:125858. doi: 10.1155/2013/125858. Epub 2013 Jan 15.

26.

Targeting costimulatory molecules to improve antitumor immunity.

Capece D, Verzella D, Fischietti M, Zazzeroni F, Alesse E.

J Biomed Biotechnol. 2012;2012:926321. doi: 10.1155/2012/926321. Epub 2012 Feb 12. Review.

27.

The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors.

Silvano E, Millan MJ, Mannoury la Cour C, Han Y, Duan L, Griffin SA, Luedtke RR, Aloisi G, Rossi M, Zazzeroni F, Javitch JA, Maggio R.

Mol Pharmacol. 2010 Nov;78(5):925-34. doi: 10.1124/mol.110.065755. Epub 2010 Aug 11.

28.

The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors.

Mancarelli MM, Zazzeroni F, Ciccocioppo L, Capece D, Po A, Murgo S, Di Camillo R, Rinaldi C, Ferretti E, Gulino A, Alesse E.

Mol Cancer. 2010 Jun 30;9:172. doi: 10.1186/1476-4598-9-172.

29.

The glycosaminoglycan-binding domain of PRELP acts as a cell type-specific NF-kappaB inhibitor that impairs osteoclastogenesis.

Rucci N, Rufo A, Alamanou M, Capulli M, Del Fattore A, Ahrman E, Capece D, Iansante V, Zazzeroni F, Alesse E, Heinegård D, Teti A.

J Cell Biol. 2009 Nov 30;187(5):669-83. doi: 10.1083/jcb.200906014.

30.

Mechanisms of liver disease: cross-talk between the NF-kappaB and JNK pathways.

Papa S, Bubici C, Zazzeroni F, Franzoso G.

Biol Chem. 2009 Oct;390(10):965-76. doi: 10.1515/BC.2009.111. Review.

31.

The NF-kappaB transcription factor pathway as a therapeutic target in cancer: methods for detection of NF-kappaB activity.

Mauro C, Zazzeroni F, Papa S, Bubici C, Franzoso G.

Methods Mol Biol. 2009;512:169-207. doi: 10.1007/978-1-60327-530-9_10.

PMID:
19347278
32.

Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling.

Papa S, Zazzeroni F, Fu YX, Bubici C, Alvarez K, Dean K, Christiansen PA, Anders RA, Franzoso G.

J Clin Invest. 2008 May;118(5):1911-23. doi: 10.1172/JCI33913.

33.

Nifedipine improves the migratory ability of circulating endothelial progenitor cells depending on manganese superoxide dismutase upregulation.

Passacquale G, Desideri G, Croce G, Murgo S, Mancarelli MM, Zazzeroni F, Alesse E, Ferri C.

J Hypertens. 2008 Apr;26(4):737-46. doi: 10.1097/HJH.0b013e3282f4d1bd.

PMID:
18327084
34.

A method for isolating prosurvival targets of NF-kappaB/Rel transcription factors.

Kuntzen C, Zazzeroni F, Pham CG, Papa S, Bubici C, Knabb JR, Franzoso G.

Methods Mol Biol. 2007;399:99-124. Review.

PMID:
18309928
35.

Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs.

Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C, Franzoso G.

Mol Cell Biol. 2007 Jun;27(11):3920-35. Epub 2007 Apr 2.

36.

The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.

Papa S, Bubici C, Zazzeroni F, Pham CG, Kuntzen C, Knabb JR, Dean K, Franzoso G.

Cell Death Differ. 2006 May;13(5):712-29. Review.

37.

In the Crosshairs: NF-κB Targets the JNK Signaling Cascade.

Pham CG, Papa S, Bubici C, Zazzeroni F, Franzoso G.

Curr Med Chem Anti Inflamm Anti Allergy Agents. 2005 Dec 1;4(6):569-576.

38.

The NF-kappaB-mediated control of ROS and JNK signaling.

Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G.

Histol Histopathol. 2006 Jan;21(1):69-80. doi: 10.14670/HH-21.69. Review.

PMID:
16267788
39.

NF-kappaB meets ROS: an 'iron-ic' encounter.

Papa S, Bubici C, Pham CG, Zazzeroni F, Franzoso G.

Cell Death Differ. 2005 Oct;12(10):1259-62. No abstract available.

40.

Oxygen JNKies: phosphatases overdose on ROS.

Pham CG, Papa S, Bubici C, Zazzeroni F, Franzoso G.

Dev Cell. 2005 Apr;8(4):452-4.

41.

NF-kappaB and JNK: an intricate affair.

Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G.

Cell Cycle. 2004 Dec;3(12):1524-9. Epub 2004 Dec 19. Review.

PMID:
15611622
42.

Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species.

Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, Jayawardena S, De Smaele E, Cong R, Beaumont C, Torti FM, Torti SV, Franzoso G.

Cell. 2004 Nov 12;119(4):529-42.

43.

Linking JNK signaling to NF-kappaB: a key to survival.

Papa S, Zazzeroni F, Pham CG, Bubici C, Franzoso G.

J Cell Sci. 2004 Oct 15;117(Pt 22):5197-208. Review.

44.

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.

Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F, Gallo R, Masuelli L, Napolitano M, Maroder M, Modesti A, Giangaspero F, Screpanti I, Alesse E, Gulino A.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10833-8. Epub 2004 Jul 12.

45.

Human pituitary tumours express the bHLH transcription factors NeuroD1 and ASH1.

Ferretti E, Di Stefano D, Zazzeroni F, Gallo R, Fratticci A, Carfagnini R, Angiulli S, Santoro A, Minniti G, Tamburrano G, Alesse E, Cantore G, Gulino A, Jaffrain-Rea ML.

J Endocrinol Invest. 2003 Oct;26(10):957-65.

PMID:
14759067
46.

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2.

Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, De Smaele E, Tang WJ, D'Adamio L, Franzoso G.

Nat Cell Biol. 2004 Feb;6(2):146-53. Epub 2004 Jan 25.

PMID:
14743220
47.

NF-kappaB protects from the lysosomal pathway of cell death.

Liu N, Raja SM, Zazzeroni F, Metkar SS, Shah R, Zhang M, Wang Y, Brömme D, Russin WA, Lee JC, Peter ME, Froelich CJ, Franzoso G, Ashton-Rickardt PG.

EMBO J. 2003 Oct 1;22(19):5313-22.

48.

Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis.

Zazzeroni F, Papa S, Algeciras-Schimnich A, Alvarez K, Melis T, Bubici C, Majewski N, Hay N, De Smaele E, Peter ME, Franzoso G.

Blood. 2003 Nov 1;102(9):3270-9. Epub 2003 Jul 10.

49.

JNK: a killer on a transcriptional leash.

Franzoso G, Zazzeroni F, Papa S.

Cell Death Differ. 2003 Jan;10(1):13-5. Review. No abstract available.

50.

REN: a novel, developmentally regulated gene that promotes neural cell differentiation.

Gallo R, Zazzeroni F, Alesse E, Mincione C, Borello U, Buanne P, D'Eugenio R, Mackay AR, Argenti B, Gradini R, Russo MA, Maroder M, Cossu G, Frati L, Screpanti I, Gulino A.

J Cell Biol. 2002 Aug 19;158(4):731-40. Epub 2002 Aug 19.

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