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Items: 25

1.

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau5612. doi: 10.1126/scitranslmed.aau5612.

PMID:
30842315
2.

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.

Brinson RG, Marino JP, Delaglio F, Arbogast LW, Evans RM, Kearsley A, Gingras G, Ghasriani H, Aubin Y, Pierens GK, Jia X, Mobli M, Grant HG, Keizer DW, Schweimer K, Ståhle J, Widmalm G, Zartler ER, Lawrence CW, Reardon PN, Cort JR, Xu P, Ni F, Yanaka S, Kato K, Parnham SR, Tsao D, Blomgren A, Rundlöf T, Trieloff N, Schmieder P, Ross A, Skidmore K, Chen K, Keire D, Freedberg DI, Suter-Stahel T, Wider G, Ilc G, Plavec J, Bradley SA, Baldisseri DM, Sforça ML, Zeri ACM, Wei JY, Szabo CM, Amezcua CA, Jordan JB, Wikström M.

MAbs. 2019 Jan;11(1):94-105. doi: 10.1080/19420862.2018.1544454. Epub 2018 Dec 22.

3.

Fragonomics: the -omics with real impact.

Zartler ER.

ACS Med Chem Lett. 2014 Aug 13;5(9):952-3. doi: 10.1021/ml5003212. eCollection 2014 Sep 11.

4.

Saturation transfer difference NMR for fragment screening.

Begley DW, Moen SO, Pierce PG, Zartler ER.

Curr Protoc Chem Biol. 2013;5(4):251-68. doi: 10.1002/9780470559277.ch130118.

PMID:
24391096
5.

Streptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units.

Oliver MB, Jones C, Larson TR, Calix JJ, Zartler ER, Yother J, Nahm MH.

J Biol Chem. 2013 Jul 26;288(30):21945-54. doi: 10.1074/jbc.M113.488528. Epub 2013 Jun 4.

6.

The use of 1H-31P GHMBC and covariance NMR to unambiguously determine phosphate ester linkages in complex polysaccharide mixtures.

Zartler ER, Martin GE.

J Biomol NMR. 2011 Nov;51(3):357-67. doi: 10.1007/s10858-011-9563-8. Epub 2011 Sep 16.

PMID:
21922277
7.

Elucidation of structural and antigenic properties of pneumococcal serotype 11A, 11B, 11C, and 11F polysaccharide capsules.

Calix JJ, Nahm MH, Zartler ER.

J Bacteriol. 2011 Oct;193(19):5271-8. doi: 10.1128/JB.05034-11. Epub 2011 Jul 29. Erratum in: J Bacteriol. 2012 Jan;194(1):206. J Bacteriol. 2013 Oct;195(19):4552.

8.

Structural elucidation of an α-1,2-mannosidase resistant oligosaccharide produced in Pichia pastoris.

Gomathinayagam S, Mitchell T, Zartler ER, Heiss C, Azadi P, Zha D, Houston-Cummings NR, Jiang Y, Li F, Giaccone E, Porambo RJ, Anderson CL, Sethuraman N, Li H, Stadheim TA.

Glycobiology. 2011 Dec;21(12):1606-15. doi: 10.1093/glycob/cwr082. Epub 2011 Jul 27.

PMID:
21798867
9.

Identification of 3-O-acetylglycerol, a novel structural element in bacterial polysaccharides.

Zartler ER, Porambo RJ, Anderson CL, Yu J, Nahm MH.

Carbohydr Res. 2009 Dec 14;344(18):2586-90. doi: 10.1016/j.carres.2009.09.019. Epub 2009 Sep 22.

10.

Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes.

Zartler ER, Porambo RJ, Anderson CL, Chen LH, Yu J, Nahm MH.

J Biol Chem. 2009 Mar 13;284(11):7318-29. doi: 10.1074/jbc.M807952200. Epub 2008 Dec 29. Erratum in: J Biol Chem. 2011 Dec 16;286(50):43588. J Biol Chem. 2011 Mar 11;286(10):8707.

11.

Practical aspects of NMR-based fragment discovery.

Zartler ER, Mo H.

Curr Top Med Chem. 2007;7(16):1592-9.

PMID:
17979770
12.

Protein NMR-based screening in drug discovery.

Zartler ER, Shapiro MJ.

Curr Pharm Des. 2006;12(31):3963-72. Review.

PMID:
17100607
13.

Fragonomics: fragment-based drug discovery.

Zartler ER, Shapiro MJ.

Curr Opin Chem Biol. 2005 Aug;9(4):366-70. Review.

PMID:
15925537
14.

Application of residual dipolar couplings in organic compounds.

Yan J, Zartler ER.

Magn Reson Chem. 2005 Jan;43(1):53-64.

PMID:
15578593
15.

The absolute sign of J coupling constants determined using the order matrix calculation.

Yan J, Kline AD, Mo H, Shapiro MJ, Zartler ER.

Magn Reson Chem. 2004 Nov;42(11):962-7.

PMID:
15386557
16.

Complete relative stereochemistry of multiple stereocenters using only residual dipolar couplings.

Yan J, Delaglio F, Kaerner A, Kline AD, Mo H, Shapiro MJ, Smitka TA, Stephenson GA, Zartler ER.

J Am Chem Soc. 2004 Apr 21;126(15):5008-17.

PMID:
15080707
17.

RAMPED-UP NMR: multiplexed NMR-based screening for drug discovery.

Zartler ER, Hanson J, Jones BE, Kline AD, Martin G, Mo H, Shapiro MJ, Wang R, Wu H, Yan J.

J Am Chem Soc. 2003 Sep 10;125(36):10941-6.

PMID:
12952475
18.

The effect of relaxation on the epitope mapping by saturation transfer difference NMR.

Yan J, Kline AD, Mo H, Shapiro MJ, Zartler ER.

J Magn Reson. 2003 Aug;163(2):270-6.

PMID:
12914842
19.

A novel method for the determination of stereochemistry in six-membered chairlike rings using residual dipolar couplings.

Yan J, Kline AD, Mo H, Shapiro MJ, Zartler ER.

J Org Chem. 2003 Mar 7;68(5):1786-95.

PMID:
12608792
20.

Transferred nuclear overhauser effect in nuclear magnetic resonance diffusion measurements of ligand-protein binding.

Lucas LH, Yan J, Larive CK, Zartler ER, Shapiro MJ.

Anal Chem. 2003 Feb 1;75(3):627-34.

PMID:
12585494
21.

ID NMR Methods in ligand-receptor interactions.

Zartler ER, Yan J, Mo H, Kline AD, Shapiro MJ.

Curr Top Med Chem. 2003;3(1):25-37. Review.

PMID:
12577989
22.

Epitope mapping of ligand-receptor interactions by diffusion NMR.

Yan J, Kline AD, Mo H, Zartler ER, Shapiro MJ.

J Am Chem Soc. 2002 Aug 28;124(34):9984-5.

PMID:
12188651
23.

Structural basis for thermostability in aporubredoxins from Pyrococcus furiosus and Clostridium pasteurianum.

Zartler ER, Jenney FE Jr, Terrell M, Eidsness MK, Adams MW, Prestegard JH.

Biochemistry. 2001 Jun 19;40(24):7279-90.

PMID:
11401576
24.

Direct measurement of 1H-1H dipolar couplings in proteins: a complement to traditional NOE measurements.

Tian F, Fowler CA, Zartler ER, Jenney FA Jr, Adams MW, Prestegard JH.

J Biomol NMR. 2000 Sep;18(1):23-31.

PMID:
11061225
25.

Variation of molecular alignment as a means of resolving orientational ambiguities in protein structures from dipolar couplings.

Al-Hashimi HM, Valafar H, Terrell M, Zartler ER, Eidsness MK, Prestegard JH.

J Magn Reson. 2000 Apr;143(2):402-6.

PMID:
10729267

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