Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35

1.

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

Hirose M, Schilf P, Gupta Y, Zarse K, Künstner A, Fähnrich A, Busch H, Yin J, Wright MN, Ziegler A, Vallier M, Belheouane M, Baines JF, Tautz D, Johann K, Oelkrug R, Mittag J, Lehnert H, Othman A, Jöhren O, Schwaninger M, Prehn C, Adamski J, Shima K, Rupp J, Häsler R, Fuellen G, Köhling R, Ristow M, Ibrahim SM.

Sci Rep. 2018 Apr 12;8(1):5872. doi: 10.1038/s41598-018-24290-6.

2.

Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.

Ravichandran M, Priebe S, Grigolon G, Rozanov L, Groth M, Laube B, Guthke R, Platzer M, Zarse K, Ristow M.

Cell Metab. 2018 Apr 3;27(4):914-925.e5. doi: 10.1016/j.cmet.2018.02.004. Epub 2018 Mar 15.

PMID:
29551589
3.

Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan.

Merry TL, Kuhlow D, Laube B, Pöhlmann D, Pfeiffer AFH, Kahn CR, Ristow M, Zarse K.

Aging Cell. 2017 Aug;16(4):761-772. doi: 10.1111/acel.12610. Epub 2017 May 22.

4.

A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism.

Gebauer J, Gentsch C, Mansfeld J, Schmeißer K, Waschina S, Brandes S, Klimmasch L, Zamboni N, Zarse K, Schuster S, Ristow M, Schäuble S, Kaleta C.

Cell Syst. 2016 May 25;2(5):312-22. doi: 10.1016/j.cels.2016.04.017. Epub 2016 May 19.

5.

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M.

Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043.

6.

A mitochondrially encoded hormone ameliorates obesity and insulin resistance.

Zarse K, Ristow M.

Cell Metab. 2015 Mar 3;21(3):355-6. doi: 10.1016/j.cmet.2015.02.013.

7.

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.

Boucher J, Charalambous M, Zarse K, Mori MA, Kleinridders A, Ristow M, Ferguson-Smith AC, Kahn CR.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14512-7. doi: 10.1073/pnas.1415475111. Epub 2014 Sep 22.

8.

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M.

Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.

9.

Extension of life span by impaired glucose metabolism in Caenorhabditis elegans is accompanied by structural rearrangements of the transcriptomic network.

Priebe S, Menzel U, Zarse K, Groth M, Platzer M, Ristow M, Guthke R.

PLoS One. 2013 Oct 30;8(10):e77776. doi: 10.1371/journal.pone.0077776. eCollection 2013.

10.

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M.

Nat Chem Biol. 2013 Nov;9(11):693-700. doi: 10.1038/nchembio.1352. Epub 2013 Sep 29.

11.

Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner.

Brandstädt S, Schmeisser K, Zarse K, Ristow M.

Aging (Albany NY). 2013 Apr;5(4):270-5.

12.

Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension.

Schmeisser S, Schmeisser K, Weimer S, Groth M, Priebe S, Fazius E, Kuhlow D, Pick D, Einax JW, Guthke R, Platzer M, Zarse K, Ristow M.

Aging Cell. 2013 Jun;12(3):508-17. doi: 10.1111/acel.12076. Epub 2013 May 6.

13.

Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal.

Zarse K, Schmeisser S, Groth M, Priebe S, Beuster G, Kuhlow D, Guthke R, Platzer M, Kahn CR, Ristow M.

Cell Metab. 2012 Apr 4;15(4):451-65. doi: 10.1016/j.cmet.2012.02.013.

14.

L-Theanine extends lifespan of adult Caenorhabditis elegans.

Zarse K, Jabin S, Ristow M.

Eur J Nutr. 2012 Sep;51(6):765-8. doi: 10.1007/s00394-012-0341-5. Epub 2012 Mar 16.

15.

Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species.

Schmeisser S, Zarse K, Ristow M.

Horm Metab Res. 2011 Sep;43(10):687-92. doi: 10.1055/s-0031-1286308. Epub 2011 Sep 19.

PMID:
21932172
16.

Dual role of the mitochondrial protein frataxin in astrocytic tumors.

Kirches E, Andrae N, Hoefer A, Kehler B, Zarse K, Leverkus M, Keilhoff G, Schonfeld P, Schneider T, Wilisch-Neumann A, Mawrin C.

Lab Invest. 2011 Dec;91(12):1766-76. doi: 10.1038/labinvest.2011.130. Epub 2011 Aug 22.

17.

Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth.

Beuster G, Zarse K, Kaleta C, Thierbach R, Kiehntopf M, Steinberg P, Schuster S, Ristow M.

J Biol Chem. 2011 Jun 24;286(25):22323-30. doi: 10.1074/jbc.M110.205229. Epub 2011 May 3.

18.

Low-dose lithium uptake promotes longevity in humans and metazoans.

Zarse K, Terao T, Tian J, Iwata N, Ishii N, Ristow M.

Eur J Nutr. 2011 Aug;50(5):387-9. doi: 10.1007/s00394-011-0171-x. Epub 2011 Feb 8.

19.

The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans.

Zarse K, Bossecker A, Müller-Kuhrt L, Siems K, Hernandez MA, Berendsohn WG, Birringer M, Ristow M.

Horm Metab Res. 2011 Apr;43(4):241-3. doi: 10.1055/s-0030-1270524. Epub 2011 Jan 24.

PMID:
21264793
20.

Activation of mitochondrial energy metabolism protects against cardiac failure.

Schulz TJ, Westermann D, Isken F, Voigt A, Laube B, Thierbach R, Kuhlow D, Zarse K, Schomburg L, Pfeiffer AF, Tschöpe C, Ristow M.

Aging (Albany NY). 2010 Nov;2(11):843-53.

21.

Serum vaspin concentrations are decreased after exercise-induced oxidative stress.

Oberbach A, Kirsch K, Lehmann S, Schlichting N, Fasshauer M, Zarse K, Stumvoll M, Ristow M, Blüher M, Kovacs P.

Obes Facts. 2010 Oct;3(5):328-31. doi: 10.1159/000321637. Epub 2010 Oct 20.

22.

Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans.

Zarse K, Schmeisser S, Birringer M, Falk E, Schmoll D, Ristow M.

Horm Metab Res. 2010 Nov;42(12):837-9. doi: 10.1055/s-0030-1265225. Epub 2010 Oct 5.

PMID:
20925017
23.

Telomerase deficiency impairs glucose metabolism and insulin secretion.

Kuhlow D, Florian S, von Figura G, Weimer S, Schulz N, Petzke KJ, Zarse K, Pfeiffer AF, Rudolph KL, Ristow M.

Aging (Albany NY). 2010 Oct;2(10):650-8.

24.

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis).

Ristow M, Zarse K.

Exp Gerontol. 2010 Jun;45(6):410-8. doi: 10.1016/j.exger.2010.03.014. Epub 2010 Mar 27. Review.

PMID:
20350594
25.

Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice.

Kuhlow D, Zarse K, Voigt A, Schulz TJ, Petzke KJ, Schomburg L, Pfeiffer AF, Ristow M.

Eur J Nutr. 2010 Oct;49(7):417-27. doi: 10.1007/s00394-010-0100-4. Epub 2010 Mar 10.

PMID:
20221766
26.

Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes.

Perwitz N, Wenzel J, Wagner I, Büning J, Drenckhan M, Zarse K, Ristow M, Lilienthal W, Lehnert H, Klein J.

Diabetes Obes Metab. 2010 Feb;12(2):158-66. doi: 10.1111/j.1463-1326.2009.01133.x. Epub 2009 Nov 5.

PMID:
19895638
27.

Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag.

Ripcke J, Zarse K, Ristow M, Birringer M.

Chembiochem. 2009 Jul 6;10(10):1689-96. doi: 10.1002/cbic.200900159.

PMID:
19492396
28.

Antioxidants prevent health-promoting effects of physical exercise in humans.

Ristow M, Zarse K, Oberbach A, Klöting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Blüher M.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8665-70. doi: 10.1073/pnas.0903485106. Epub 2009 May 11.

29.

Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans.

Zarse K, Ristow M.

PLoS One. 2008;3(12):e4062. doi: 10.1371/journal.pone.0004062. Epub 2008 Dec 29.

30.

Intracellular degradation of somatostatin-14 following somatostatin-receptor3-mediated endocytosis in rat insulinoma cells.

Roosterman D, Brune NE, Kreuzer OJ, Feld M, Pauser S, Zarse K, Steinhoff M, Meyerhof W.

FEBS J. 2008 Oct;275(19):4728-39. doi: 10.1111/j.1742-4658.2008.06606.x. Epub 2008 Aug 13.

31.

A cell-based high-throughput assay system reveals modulation of oxidative and nonoxidative glucose metabolism due to commonly used organic solvents.

Zimmermann S, Zarse K, Schulz TJ, Siems K, Müller-Kuhrt L, Birringer M, Ristow M.

Horm Metab Res. 2008 Jan;40(1):29-37. doi: 10.1055/s-2007-1004542.

PMID:
18197582
32.

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress.

Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M.

Cell Metab. 2007 Oct;6(4):280-93.

33.

Impaired respiration is positively correlated with decreased life span in Caenorhabditis elegans models of Friedreich Ataxia.

Zarse K, Schulz TJ, Birringer M, Ristow M.

FASEB J. 2007 Apr;21(4):1271-5. Epub 2007 Jan 10.

PMID:
17215485
34.

Development of peptide microarrays for epitope mapping of antibodies against the human TSH receptor.

Andresen H, Zarse K, Grötzinger C, Hollidt JM, Ehrentreich-Förster E, Bier FF, Kreuzer OJ.

J Immunol Methods. 2006 Aug 31;315(1-2):11-8. Epub 2006 Jul 14.

PMID:
16920148
35.

Functional peptide microarrays for specific and sensitive antibody diagnostics.

Andresen H, Grötzinger C, Zarse K, Kreuzer OJ, Ehrentreich-Förster E, Bier FF.

Proteomics. 2006 Mar;6(5):1376-84.

PMID:
16456884

Supplemental Content

Support Center