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Items: 38

1.

TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome.

Myles IA, Anderson ED, Earland NJ, Zarember KA, Sastalla I, Williams KW, Gough P, Moore IN, Ganesan S, Fowler CJ, Laurence A, Garofalo M, Kuhns DB, Kieh MD, Saleem A, Welch PA, Darnell DA, Gallin JI, Freeman AF, Holland SM, Datta SK.

J Clin Invest. 2018 Aug 1;128(8):3595-3604. doi: 10.1172/JCI121486. Epub 2018 Jul 23.

2.

Early Intracellular Trafficking of Granulibacter bethesdensis in Human Macrophages.

Chu J, Smelkinson MG, Dorward DW, Zarember KA, Gallin JI.

Infect Immun. 2017 May 23;85(6). pii: e00847-16. doi: 10.1128/IAI.00847-16. Print 2017 Jun.

3.

CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease.

De Ravin SS, Li L, Wu X, Choi U, Allen C, Koontz S, Lee J, Theobald-Whiting N, Chu J, Garofalo M, Sweeney C, Kardava L, Moir S, Viley A, Natarajan P, Su L, Kuhns D, Zarember KA, Peshwa MV, Malech HL.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaah3480. doi: 10.1126/scitranslmed.aah3480.

PMID:
28077679
4.

Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiency.

Kuhns DB, Fink DL, Choi U, Sweeney C, Lau K, Priel DL, Riva D, Mendez L, Uzel G, Freeman AF, Olivier KN, Anderson VL, Currens R, Mackley V, Kang A, Al-Adeli M, Mace E, Orange JS, Kang E, Lockett SJ, Chen, Steinbach PJ, Hsu AP, Zarember KA, Malech HL, Gallin JI, Holland SM.

Blood. 2016 Oct 27;128(17):2135-2143. Epub 2016 Aug 24.

5.

Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience.

Feingold PL, Quadri HS, Steinberg SM, Malech HL, Gallin JI, Zerbe CS, Zarember KA, Marciano BE, Holland SM, Schrump DS, Ripley RT.

J Clin Immunol. 2016 Oct;36(7):677-83. doi: 10.1007/s10875-016-0319-9. Epub 2016 Aug 6.

6.

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency.

De Ravin SS, Wu X, Moir S, Anaya-O'Brien S, Kwatemaa N, Littel P, Theobald N, Choi U, Su L, Marquesen M, Hilligoss D, Lee J, Buckner CM, Zarember KA, O'Connor G, McVicar D, Kuhns D, Throm RE, Zhou S, Notarangelo LD, Hanson IC, Cowan MJ, Kang E, Hadigan C, Meagher M, Gray JT, Sorrentino BP, Malech HL, Kardava L.

Sci Transl Med. 2016 Apr 20;8(335):335ra57. doi: 10.1126/scitranslmed.aad8856. Erratum in: Sci Transl Med. 2016 Jun 1;8(341):341er5.

7.

Targeted gene addition in human CD34(+) hematopoietic cells for correction of X-linked chronic granulomatous disease.

De Ravin SS, Reik A, Liu PQ, Li L, Wu X, Su L, Raley C, Theobald N, Choi U, Song AH, Chan A, Pearl JR, Paschon DE, Lee J, Newcombe H, Koontz S, Sweeney C, Shivak DA, Zarember KA, Peshwa MV, Gregory PD, Urnov FD, Malech HL.

Nat Biotechnol. 2016 Apr;34(4):424-9. doi: 10.1038/nbt.3513. Epub 2016 Mar 7.

8.

Isolation and Functional Analysis of Human Neutrophils.

Kuhns DB, Long Priel DA, Chu J, Zarember KA.

Curr Protoc Immunol. 2015 Nov 2;111:7.23.1-16. doi: 10.1002/0471142735.im0723s111.

9.

Simultaneous Host-Pathogen Transcriptome Analysis during Granulibacter bethesdensis Infection of Neutrophils from Healthy Subjects and Patients with Chronic Granulomatous Disease.

Greenberg DE, Sturdevant DE, Marshall-Batty KR, Chu J, Pettinato AM, Virtaneva K, Lane J, Geller BL, Porcella SF, Gallin JI, Holland SM, Zarember KA.

Infect Immun. 2015 Nov;83(11):4277-92. doi: 10.1128/IAI.00778-15. Epub 2015 Aug 17.

10.

An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease.

Merling RK, Sweeney CL, Chu J, Bodansky A, Choi U, Priel DL, Kuhns DB, Wang H, Vasilevsky S, De Ravin SS, Winkler T, Dunbar CE, Zou J, Zarember KA, Gallin JI, Holland SM, Malech HL.

Mol Ther. 2015 Jan;23(1):147-57. doi: 10.1038/mt.2014.195. Epub 2014 Oct 7.

11.

Assessment of atherosclerosis in chronic granulomatous disease.

Sibley CT, Estwick T, Zavodni A, Huang CY, Kwan AC, Soule BP, Long Priel DA, Remaley AT, Rudman Spergel AK, Turkbey EB, Kuhns DB, Holland SM, Malech HL, Zarember KA, Bluemke DA, Gallin JI.

Circulation. 2014 Dec 2;130(23):2031-9. doi: 10.1161/CIRCULATIONAHA.113.006824. Epub 2014 Sep 19.

12.

Persistence of the bacterial pathogen Granulibacter bethesdensis in chronic granulomatous disease monocytes and macrophages lacking a functional NADPH oxidase.

Chu J, Song HH, Zarember KA, Mills TA, Gallin JI.

J Immunol. 2013 Sep 15;191(6):3297-307. doi: 10.4049/jimmunol.1300200. Epub 2013 Aug 16.

13.

B-cell activating factor (BAFF) is elevated in chronic granulomatous disease.

Matharu K, Zarember KA, Marciano BE, Kuhns DB, Spalding C, Garofalo M, Dimaggio T, Estwick T, Huang CY, Fink D, Priel DL, Fleisher TA, Holland SM, Malech HL, Gallin JI.

Clin Immunol. 2013 Aug;148(2):258-64. doi: 10.1016/j.clim.2013.05.007. Epub 2013 May 22.

14.

Intermediate phenotypes in patients with autosomal dominant hyper-IgE syndrome caused by somatic mosaicism.

Hsu AP, Sowerwine KJ, Lawrence MG, Davis J, Henderson CJ, Zarember KA, Garofalo M, Gallin JI, Kuhns DB, Heller T, Milner JD, Puck JM, Freeman AF, Holland SM.

J Allergy Clin Immunol. 2013 Jun;131(6):1586-93. doi: 10.1016/j.jaci.2013.02.038. Epub 2013 Apr 25.

15.

Serologic reactivity to the emerging pathogen Granulibacter bethesdensis.

Greenberg DE, Shoffner AR, Marshall-Batty KR, Arora K, Zhao M, Martin R, Ding L, Hammer CH, Shaw PA, Kuhns DB, Malech HL, Gallin JI, Zarember KA, Holland SM.

J Infect Dis. 2012 Sep 15;206(6):943-51. doi: 10.1093/infdis/jis431. Epub 2012 Jul 10.

16.

Innate immunity against Granulibacter bethesdensis, an emerging gram-negative bacterial pathogen.

Zarember KA, Marshall-Batty KR, Cruz AR, Chu J, Fenster ME, Shoffner AR, Rogge LS, Whitney AR, Czapiga M, Song HH, Shaw PA, Nagashima K, Malech HL, DeLeo FR, Holland SM, Gallin JI, Greenberg DE.

Infect Immun. 2012 Mar;80(3):975-81. doi: 10.1128/IAI.05557-11. Epub 2011 Dec 19.

17.

Editorial: will the real neutrophil please stand up?

Zarember KA, Kuhns DB.

J Leukoc Biol. 2011 Dec;90(6):1039-41. doi: 10.1189/jlb.0711334. No abstract available.

18.

Chronic granulomatous disease: overview and hematopoietic stem cell transplantation.

Kang EM, Marciano BE, DeRavin S, Zarember KA, Holland SM, Malech HL.

J Allergy Clin Immunol. 2011 Jun;127(6):1319-26; quiz 1327-8. doi: 10.1016/j.jaci.2011.03.028. Epub 2011 Apr 17. Review.

19.

Residual NADPH oxidase and survival in chronic granulomatous disease.

Kuhns DB, Alvord WG, Heller T, Feld JJ, Pike KM, Marciano BE, Uzel G, DeRavin SS, Priel DA, Soule BP, Zarember KA, Malech HL, Holland SM, Gallin JI.

N Engl J Med. 2010 Dec 30;363(27):2600-10. doi: 10.1056/NEJMoa1007097.

20.

Recurrent Granulibacter bethesdensis infections and chronic granulomatous disease.

Greenberg DE, Shoffner AR, Zelazny AM, Fenster ME, Zarember KA, Stock F, Ding L, Marshall-Batty KR, Wasserman RL, Welch DF, Kanakabandi K, Sturdevant DE, Virtaneva K, Porcella SF, Murray PR, Malech HL, Holland SM.

Emerg Infect Dis. 2010 Sep;16(9):1341-8. doi: 10.3201/eid1609.091800.

21.

Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease.

De Ravin SS, Zarember KA, Long-Priel D, Chan KC, Fox SD, Gallin JI, Kuhns DB, Malech HL.

Blood. 2010 Sep 9;116(10):1755-60. doi: 10.1182/blood-2009-07-233734. Epub 2010 May 28.

22.

Hypomorphic Rag mutations can cause destructive midline granulomatous disease.

De Ravin SS, Cowen EW, Zarember KA, Whiting-Theobald NL, Kuhns DB, Sandler NG, Douek DC, Pittaluga S, Poliani PL, Lee YN, Notarangelo LD, Wang L, Alt FW, Kang EM, Milner JD, Niemela JE, Fontana-Penn M, Sinal SH, Malech HL.

Blood. 2010 Aug 26;116(8):1263-71. doi: 10.1182/blood-2010-02-267583. Epub 2010 May 20.

23.

Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex.

Greenberg DE, Marshall-Batty KR, Brinster LR, Zarember KA, Shaw PA, Mellbye BL, Iversen PL, Holland SM, Geller BL.

J Infect Dis. 2010 Jun 15;201(12):1822-30. doi: 10.1086/652807.

24.

Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency.

Singh A, Zarember KA, Kuhns DB, Gallin JI.

J Immunol. 2009 May 15;182(10):6410-7. doi: 10.4049/jimmunol.0802512.

25.

Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.

Zarember KA, Cruz AR, Huang CY, Gallin JI.

Antimicrob Agents Chemother. 2009 Jun;53(6):2654-6. doi: 10.1128/AAC.01547-08. Epub 2009 Mar 23.

26.

Short stature in partially corrected X-linked severe combined immunodeficiency--suboptimal response to growth hormone.

De Ravin SS, Shum E, Zarember KA, Rezvani G, Rosenfeld RG, Stratakis CA, Malech HL.

J Pediatr Endocrinol Metab. 2008 Nov;21(11):1057-63.

27.

Genes differentially expressed in conidia and hyphae of Aspergillus fumigatus upon exposure to human neutrophils.

Sugui JA, Kim HS, Zarember KA, Chang YC, Gallin JI, Nierman WC, Kwon-Chung KJ.

PLoS One. 2008 Jul 9;3(7):e2655. doi: 10.1371/journal.pone.0002655.

28.

Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.

Sugui JA, Pardo J, Chang YC, Müllbacher A, Zarember KA, Galvez EM, Brinster L, Zerfas P, Gallin JI, Simon MM, Kwon-Chung KJ.

Eukaryot Cell. 2007 Sep;6(9):1552-61. Epub 2007 Jul 13.

29.

Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.

Sugui JA, Pardo J, Chang YC, Zarember KA, Nardone G, Galvez EM, Müllbacher A, Gallin JI, Simon MM, Kwon-Chung KJ.

Eukaryot Cell. 2007 Sep;6(9):1562-9. Epub 2007 Jun 29.

30.

Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion.

Zarember KA, Sugui JA, Chang YC, Kwon-Chung KJ, Gallin JI.

J Immunol. 2007 May 15;178(10):6367-73.

31.

HIF-1alpha: a master regulator of innate host defenses?

Zarember KA, Malech HL.

J Clin Invest. 2005 Jul;115(7):1702-4. Review.

33.

Regulation of interactions of endotoxin with host cells.

Gioannini TL, Teghanemt A, Zarember KA, Weiss JP.

J Endotoxin Res. 2003;9(6):401-8.

PMID:
14733729
34.

APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA.

Schmidt KN, Leung B, Kwong M, Zarember KA, Satyal S, Navas TA, Wang F, Godowski PJ.

J Immunol. 2004 Jan 1;172(1):138-43.

35.

Critical role of the complement system in group B streptococcus-induced tumor necrosis factor alpha release.

Levy O, Jean-Jacques RM, Cywes C, Sisson RB, Zarember KA, Godowski PJ, Christianson JL, Guttormsen HK, Carroll MC, Nicholson-Weller A, Wessels MR.

Infect Immun. 2003 Nov;71(11):6344-53.

36.

Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes.

Zarember KA, Katz SS, Tack BF, Doukhan L, Weiss J, Elsbach P.

Infect Immun. 2002 Feb;70(2):569-76.

37.

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