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Coronaviruses and SARS-CoV-2: A Brief Overview.

Ludwig S, Zarbock A.

Anesth Analg. 2020 Mar 31. doi: 10.1213/ANE.0000000000004845. [Epub ahead of print]


[Update: Renal Replacement Therapy].

Massoth C, Zarbock A.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2020 Mar;55(3):178-189. doi: 10.1055/a-0853-3928. Epub 2020 Mar 19. German.


Therapeutic iloprost for the treatment of acute respiratory distress syndrome (ARDS) (the ThIlo trial): a prospective, randomized, multicenter phase II study.

Haeberle H, Prohaska S, Martus P, Straub A, Zarbock A, Marx G, Zago M, Giera M, Koeppen M, Rosenberger P.

Trials. 2020 Mar 4;21(1):242. doi: 10.1186/s13063-020-4163-0.


SLPI - a Biomarker of Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm (TAAA) Repair.

Averdunk L, Rückbeil MV, Zarbock A, Martin L, Marx G, Jalaie H, Jacobs MJ, Stoppe C, Gombert A.

Sci Rep. 2020 Feb 26;10(1):3453. doi: 10.1038/s41598-020-60482-9.


Real-time feedback improves chest compression quality in out-of-hospital cardiac arrest: A prospective cohort study.

Lakomek F, Lukas RP, Brinkrolf P, Mennewisch A, Steinsiek N, Gutendorf P, Sudowe H, Heller M, Kwiecien R, Zarbock A, Bohn A.

PLoS One. 2020 Feb 24;15(2):e0229431. doi: 10.1371/journal.pone.0229431. eCollection 2020.


The impact of acute kidney injury by serum creatinine or urine output criteria on major adverse kidney events in cardiac surgery patients.

Priyanka P, Zarbock A, Izawa J, Gleason TG, Renfurm RW, Kellum JA.

J Thorac Cardiovasc Surg. 2020 Jan 9. pii: S0022-5223(20)30029-5. doi: 10.1016/j.jtcvs.2019.11.137. [Epub ahead of print]


Protocol and statistical analysis plan for the REstricted fluid therapy VERsus Standard trEatment in Acute Kidney Injury-REVERSE-AKI randomized controlled pilot trial.

Vaara ST, Ostermann M, Selander T, Bitker L, Schneider A, Poli E, Hoste E, Joannidis M, Zarbock A, van Haren F, Prowle J, Pettilä V, Bellomo R.

Acta Anaesthesiol Scand. 2020 Feb 5. doi: 10.1111/aas.13557. [Epub ahead of print]


Intravascular adhesion and recruitment of neutrophils in response to CXCL1 depends on their TRPC6 channels.

Lindemann O, Rossaint J, Najder K, Schimmelpfennig S, Hofschröer V, Wälte M, Fels B, Oberleithner H, Zarbock A, Schwab A.

J Mol Med (Berl). 2020 Mar;98(3):349-360. doi: 10.1007/s00109-020-01872-4. Epub 2020 Jan 16.


A Multinational Observational Study Exploring Adherence With the Kidney Disease: Improving Global Outcomes Recommendations for Prevention of Acute Kidney Injury After Cardiac Surgery.

Küllmar M, Weiß R, Ostermann M, Campos S, Grau Novellas N, Thomson G, Haffner M, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima AL, García-Alvarez M, Italiano S, Felipe Correoso M, Kunst G, Nair S, L'Acqua C, Hoste E, Vandenberghe W, Honore PM, Kellum JA, Forni L, Grieshaber P, Wempe C, Meersch M, Zarbock A.

Anesth Analg. 2020 Apr;130(4):910-916. doi: 10.1213/ANE.0000000000004642.


Acute Kidney Injury.

Weiss R, Meersch M, Pavenstädt HJ, Zarbock A.

Dtsch Arztebl Int. 2019 Dec 6;116(49):833-842. doi: 10.3238/arztebl.2019.0833.


Report of the first AKI Round Table meeting: an initiative of the ESICM AKI Section.

Ostermann M, Schneider A, Rimmele T, Bobek I, van Dam M, Darmon M, Forni L, Joannes-Boyau O, Joannidis M, Legrand M, Prowle J, Zarbock A, Hoste E.

Intensive Care Med Exp. 2019 Dec 7;7(1):69. doi: 10.1186/s40635-019-0280-z.


A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Nov 19;51(5):966-967. doi: 10.1016/j.immuni.2019.11.001. No abstract available.


Vascular Adhesion Protein-1 Is Associated With Acute Kidney Injury in High-Risk Patients After Cardiac Surgery.

Meersch M, Küllmar M, Renfurm R, Margraf A, Bormann E, Zarbock A.

Anesth Analg. 2019 Dec;129(6):1474-1481. doi: 10.1213/ANE.0000000000003994.


The impact of biomarkers of acute kidney injury on individual patient care.

Koyner JL, Zarbock A, Basu RK, Ronco C.

Nephrol Dial Transplant. 2019 Nov 14. pii: gfz188. doi: 10.1093/ndt/gfz188. [Epub ahead of print]


Platelets in Inflammation and Resolution.

Margraf A, Zarbock A.

J Immunol. 2019 Nov 1;203(9):2357-2367. doi: 10.4049/jimmunol.1900899. Review.


Salvaging remote ischaemic preconditioning as a therapy for perioperative acute kidney injury.

Zarbock A, Kellum JA, Gourine AV, Ackland GL.

Br J Anaesth. 2020 Jan;124(1):8-12. doi: 10.1016/j.bja.2019.09.009. Epub 2019 Oct 17. No abstract available.


Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) Recommendations: An Important First Step-But There Is Much Work to Be Done.

Gregory AJ, Grant MC, Manning MW, Cheung AT, Ender J, Sander M, Zarbock A, Stoppe C, Meineri M, Grocott HP, Ghadimi K, Gutsche JT, Patel PA, Denault A, Shaw A, Fletcher N, Levy JH.

J Cardiothorac Vasc Anesth. 2020 Jan;34(1):39-47. doi: 10.1053/j.jvca.2019.09.002. Epub 2019 Sep 7. No abstract available.


Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis.

Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee HG, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N.

Brain. 2019 Nov 1;142(11):3411-3427. doi: 10.1093/brain/awz301.


The effects of citrate dialysate in hemodialysis on polymorphonuclear elastase interaction with tissue factor and its inhibitor.

Li J, Sun S, Han M, Wang L, Liao R, Xiong Y, Li Y, Jiang H, Qin Z, Maharjan A, Cozzolino M, Zarbock A, Su B.

Ann Transl Med. 2019 Aug;7(16):391. doi: 10.21037/atm.2019.07.57.


Risk Stratification for Targeted AKI Prevention After Surgery: Biomarkers and Bundled Interventions.

Massoth C, Zarbock A, Meersch M.

Semin Nephrol. 2019 Sep;39(5):454-461. doi: 10.1016/j.semnephrol.2019.06.005. Review.


Anesthesia-induced immune modulation.

Rossaint J, Zarbock A.

Curr Opin Anaesthesiol. 2019 Dec;32(6):799-805. doi: 10.1097/ACO.0000000000000790. Review.


L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling.

Cappenberg A, Margraf A, Thomas K, Bardel B, McCreedy DA, Van Marck V, Mellmann A, Lowell CA, Zarbock A.

Blood. 2019 Oct 24;134(17):1445-1457. doi: 10.1182/blood.2019000685.


Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel.

Guzzi LM, Bergler T, Binnall B, Engelman DT, Forni L, Germain MJ, Gluck E, Göcze I, Joannidis M, Koyner JL, Reddy VS, Rimmelé T, Ronco C, Textoris J, Zarbock A, Kellum JA.

Crit Care. 2019 Jun 20;23(1):225. doi: 10.1186/s13054-019-2504-8.


Association between urinary dickkopf-3, acute kidney injury, and subsequent loss of kidney function in patients undergoing cardiac surgery: an observational cohort study.

Schunk SJ, Zarbock A, Meersch M, Küllmar M, Kellum JA, Schmit D, Wagner M, Triem S, Wagenpfeil S, Gröne HJ, Schäfers HJ, Fliser D, Speer T, Zewinger S.

Lancet. 2019 Aug 10;394(10197):488-496. doi: 10.1016/S0140-6736(19)30769-X. Epub 2019 Jun 12.


Neutrophil Recruitment: From Model Systems to Tissue-Specific Patterns.

Margraf A, Ley K, Zarbock A.

Trends Immunol. 2019 Jul;40(7):613-634. doi: 10.1016/ Epub 2019 Jun 4. Review.


Nasolaryngeal Distances in the Adult Population and an Evaluation of Commercially Available Nasotracheal Tubes.

Massoth C, Schülke C, Köppe J, Weiss R, Pöpping D, Dahrmann M, Zarbock A, Wenk M.

Anesth Analg. 2020 Apr;130(4):1018-1025. doi: 10.1213/ANE.0000000000004241.


Commentary: Should goal-directed fluid therapy be used in every cardiac surgery patient to prevent acute kidney injury?

Zarbock A, Engelman DT.

J Thorac Cardiovasc Surg. 2019 Apr 29. pii: S0022-5223(19)30940-7. doi: 10.1016/j.jtcvs.2019.04.044. [Epub ahead of print] No abstract available.


Quality Improvement Goals for Acute Kidney Injury.

Kashani K, Rosner MH, Haase M, Lewington AJP, O'Donoghue DJ, Wilson FP, Nadim MK, Silver SA, Zarbock A, Ostermann M, Mehta RL, Kane-Gill SL, Ding X, Pickkers P, Bihorac A, Siew ED, Barreto EF, Macedo E, Kellum JA, Palevsky PM, Tolwani AJ, Ronco C, Juncos LA, Rewa OG, Bagshaw SM, Mottes TA, Koyner JL, Liu KD, Forni LG, Heung M, Wu VC.

Clin J Am Soc Nephrol. 2019 Jun 7;14(6):941-953. doi: 10.2215/CJN.01250119. Epub 2019 May 17.


[Perioperative inflammation].

Rossaint J, Margraf A, Zarbock A.

Anaesthesist. 2019 Jul;68(7):421-427. doi: 10.1007/s00101-019-0596-9. Review. German.


A Novel Approach for the Targeted Inhibition of Platelet Activation-Separating the Good From the Bad.

Rossaint J, Zarbock A.

Crit Care Med. 2019 May;47(5):741-743. doi: 10.1097/CCM.0000000000003705. No abstract available.


Commentary: Keep your ion the urine: A new way to predict postoperative acute kidney injury?

Zarbock A, Engelman DT.

J Thorac Cardiovasc Surg. 2020 Mar;159(3):928-929. doi: 10.1016/j.jtcvs.2019.02.111. Epub 2019 Mar 15. No abstract available.


[Renal replacement therapy in acute kidney injury : From the indications to cessation].

Küllmar M, Zarbock A.

Anaesthesist. 2019 Jul;68(7):485-496. doi: 10.1007/s00101-019-0587-x. German.


[Non-cardiac surgery in adults with congenital heart defects : Most important parameters in anesthesia management].

Massoth C, Zarbock A, Wenk M.

Anaesthesist. 2019 Apr;68(4):245-258. doi: 10.1007/s00101-019-0575-1. German.


Flow-controlled ventilation during ear, nose and throat surgery: A prospective observational study.

Schmidt J, Günther F, Weber J, Wirth S, Brandes I, Barnes T, Zarbock A, Schumann S, Enk D.

Eur J Anaesthesiol. 2019 May;36(5):327-334. doi: 10.1097/EJA.0000000000000967.


Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients - the study design of the LIBERAL-Trial.

Meybohm P, Lindau S, Treskatsch S, Francis R, Spies C, Velten M, Wittmann M, Gueresir E, Stoppe C, Kowark A, Coburn M, Selleng S, Baschin M, Jenichen G, Meersch M, Ermert T, Zarbock A, Kranke P, Kredel M, Helf A, Laufenberg-Feldmann R, Ferner M, Wittenmeier E, Gürtler KH, Kienbaum P, de Abreu MG, Sander M, Bauer M, Seyfried T, Gruenewald M, Choorapoikayil S, Mueller MM, Seifried E, Brosteanu O, Bogatsch H, Hasenclever D, Zacharowski K; LIBERAL Collaboration Group.

Trials. 2019 Feb 4;20(1):101. doi: 10.1186/s13063-019-3200-3.


A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29. Erratum in: Immunity. 2019 Nov 19;51(5):966-967.


Regional citrate versus systemic heparin anticoagulation for continuous renal replacement therapy in critically ill patients with acute kidney injury (RICH) trial: study protocol for a multicentre, randomised controlled trial.

Meersch M, Küllmar M, Wempe C, Kindgen-Milles D, Kluge S, Slowinski T, Marx G, Gerss J, Zarbock A; SepNet Critical Care Trials Group.

BMJ Open. 2019 Jan 21;9(1):e024411. doi: 10.1136/bmjopen-2018-024411.


High-fidelity is not superior to low-fidelity simulation but leads to overconfidence in medical students.

Massoth C, Röder H, Ohlenburg H, Hessler M, Zarbock A, Pöpping DM, Wenk M.

BMC Med Educ. 2019 Jan 21;19(1):29. doi: 10.1186/s12909-019-1464-7.


ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance.

Conrad C, Benzel J, Dorzweiler K, Cook L, Schlomann U, Zarbock A, Slater EP, Nimsky C, Bartsch JW.

Clin Sci (Lond). 2019 Jan 11;133(1):83-99. doi: 10.1042/CS20180906. Print 2019 Jan 15. Review.


Vascular Adhesion Protein-1 Is Associated With Acute Kidney Injury in High-Risk Patients After Cardiac Surgery.

Meersch M, Küllmar M, Renfurm R, Margraf A, Bormann E, Zarbock A.

Anesth Analg. 2019 Jan 8. doi: 10.1213/ANE.0000000000003994. [Epub ahead of print]


To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M.

Cell Death Differ. 2019 Mar;26(3):395-408. doi: 10.1038/s41418-018-0261-x. Epub 2019 Jan 8. Review.


Timing of Kidney Replacement Therapy in Acute Kidney Injury.

Zarbock A, Mehta RL.

Clin J Am Soc Nephrol. 2019 Jan 7;14(1):147-149. doi: 10.2215/CJN.08810718. Epub 2018 Nov 30. No abstract available.


Role of Platelets in Leukocyte Recruitment and Resolution of Inflammation.

Rossaint J, Margraf A, Zarbock A.

Front Immunol. 2018 Nov 20;9:2712. doi: 10.3389/fimmu.2018.02712. eCollection 2018. Review.


Renal biomarkers for the initiation of renal replacement therapy-is this the future?

Meersch M, Zarbock A, Küllmar M.

J Thorac Dis. 2018 Sep;10(Suppl 26):S3229-S3232. doi: 10.21037/jtd.2018.08.44. No abstract available.


Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia.

Kowark A, Adam C, Ahrens J, Bajbouj M, Bollheimer C, Borowski M, Dodel R, Dolch M, Hachenberg T, Henzler D, Hildebrand F, Hilgers RD, Hoeft A, Isfort S, Kienbaum P, Knobe M, Knuefermann P, Kranke P, Laufenberg-Feldmann R, Nau C, Neuman MD, Olotu C, Rex C, Rossaint R, Sanders RD, Schmidt R, Schneider F, Siebert H, Skorning M, Spies C, Vicent O, Wappler F, Wirtz DC, Wittmann M, Zacharowski K, Zarbock A, Coburn M; iHOPE study group.

BMJ Open. 2018 Oct 18;8(10):e023609. doi: 10.1136/bmjopen-2018-023609.


HES or How to End Science.

Weiss R, Wenk M, Van Aken H, Zwißler B, Chappell D, Zarbock A.

Anesth Analg. 2018 Dec;127(6):1440-1444. doi: 10.1213/ANE.0000000000003796. No abstract available.


Update on Perioperative Acute Kidney Injury.

Zarbock A, Koyner JL, Hoste EAJ, Kellum JA.

Anesth Analg. 2018 Nov;127(5):1236-1245. doi: 10.1213/ANE.0000000000003741. Review.


Global epidemiology and outcomes of acute kidney injury.

Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, Goldstein SL, Cerdá J, Chawla LS.

Nat Rev Nephrol. 2018 Oct;14(10):607-625. doi: 10.1038/s41581-018-0052-0. Review.


Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N.

J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4.


Availability of cookies during an academic course session affects evaluation of teaching.

Hessler M, Pöpping DM, Hollstein H, Ohlenburg H, Arnemann PH, Massoth C, Seidel LM, Zarbock A, Wenk M.

Med Educ. 2018 Oct;52(10):1064-1072. doi: 10.1111/medu.13627. Epub 2018 Jun 29.


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