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Items: 1 to 50 of 85

1.

Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.

Perez-Chacon G, Adrados M, Vallejo-Cremades MT, Lefebvre S, Reed JC, Zapata JM.

Front Immunol. 2019 Jan 11;9:3114. doi: 10.3389/fimmu.2018.03114. eCollection 2018.

2.

Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy.

Garaulet G, Pérez-Chacon G, Alarcón H, Alfranca A, Mulero F, Martínez-Torrecuadrada J, Zapata JM, Rodríguez A.

Cancer Gene Ther. 2019 Jul;26(7-8):216-233. doi: 10.1038/s41417-018-0076-4. Epub 2019 Jan 9.

PMID:
30622324
3.

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs.

Zapata JM, Perez-Chacon G, Carr-Baena P, Martinez-Forero I, Azpilikueta A, Otano I, Melero I.

Front Immunol. 2018 Nov 15;9:2618. doi: 10.3389/fimmu.2018.02618. eCollection 2018. Review.

4.

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.

Compte M, Harwood SL, Muñoz IG, Navarro R, Zonca M, Perez-Chacon G, Erce-Llamazares A, Merino N, Tapia-Galisteo A, Cuesta AM, Mikkelsen K, Caleiras E, Nuñez-Prado N, Aznar MA, Lykkemark S, Martínez-Torrecuadrada J, Melero I, Blanco FJ, Bernardino de la Serna J, Zapata JM, Sanz L, Alvarez-Vallina L.

Nat Commun. 2018 Nov 15;9(1):4809. doi: 10.1038/s41467-018-07195-w.

5.

Bioconjugation through Mesitylene Thiol Alkylation.

Ramos-Tomillero I, Perez-Chacon G, Somovilla-Crespo B, Sanchez-Madrid F, Domínguez JM, Cuevas C, Zapata JM, Rodríguez H, Albericio F.

Bioconjug Chem. 2018 Apr 18;29(4):1199-1208. doi: 10.1021/acs.bioconjchem.7b00828. Epub 2018 Mar 6.

PMID:
29433317
6.

Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).

Azpilikueta A, Bolaños E, Lang V, Labiano S, Aznar MA, Etxeberria I, Teijeira A, Rodriguez-Ruiz ME, Perez-Gracia JL, Jure-Kunkel M, Zapata JM, Rodriguez MS, Melero I.

Oncoimmunology. 2017 Sep 21;7(1):e1368605. doi: 10.1080/2162402X.2017.1368605. eCollection 2017.

7.

Fludarabine Inhibits KV1.3 Currents in Human B Lymphocytes.

de la Cruz A, Vera-Zambrano A, Peraza DA, Valenzuela C, Zapata JM, Perez-Chacon G, Gonzalez T.

Front Pharmacol. 2017 Mar 31;8:177. doi: 10.3389/fphar.2017.00177. eCollection 2017.

8.

[Characteristics and evolution of patients admitted to a public hospital intensive care unit].

Ruiz C, Díaz MÁ, Zapata JM, Bravo S, Panay S, Escobar C, Godoy J, Andresen M, Castro R.

Rev Med Chil. 2016 Oct;144(10):1297-1304. doi: 10.4067/S0034-98872016001000009. Spanish.

9.

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state.

Santacatterina F, Sánchez-Cenizo L, Formentini L, Mobasher MA, Casas E, Rueda CB, Martínez-Reyes I, Núñez de Arenas C, García-Bermúdez J, Zapata JM, Sánchez-Aragó M, Satrústegui J, Valverde ÁM, Cuezva JM.

Oncotarget. 2016 Jan 5;7(1):490-508. doi: 10.18632/oncotarget.6357.

10.

Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.

Lorenzo C, Pérez-Chacón G, Garaulet G, Mallorquín Z, Zapata JM, Rodríguez A.

Cancer Gene Ther. 2015 Nov;22(11):542-51. doi: 10.1038/cgt.2015.53. Epub 2015 Oct 9.

PMID:
26450626
11.

Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.

Perez-Chacon G, Martinez-Laperche C, Rebolleda N, Somovilla-Crespo B, Muñoz-Calleja C, Buño I, Zapata JM.

Clin Cancer Res. 2016 Jan 1;22(1):134-45. doi: 10.1158/1078-0432.CCR-15-0736. Epub 2015 Aug 31. Erratum in: Clin Cancer Res. 2017 Jun 15;23 (12 ):3226.

12.

Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines.

Perez-Chacon G, de Los Rios C, Zapata JM.

Pharmacol Res. 2014 Nov;89:46-56. doi: 10.1016/j.phrs.2014.08.005. Epub 2014 Aug 30.

13.

Arabidopsis thaliana peroxidases involved in lignin biosynthesis: in silico promoter analysis and hormonal regulation.

Herrero J, Esteban Carrasco A, Zapata JM.

Plant Physiol Biochem. 2014 Jul;80:192-202. doi: 10.1016/j.plaphy.2014.03.027. Epub 2014 Apr 3.

PMID:
24792389
14.

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.

Somovilla-Crespo B, Alfonso-Pérez M, Cuesta-Mateos C, Carballo-de Dios C, Beltrán AE, Terrón F, Pérez-Villar JJ, Gamallo-Amat C, Pérez-Chacón G, Fernández-Ruiz E, Zapata JM, Muñoz-Calleja C.

J Hematol Oncol. 2013 Dec 4;6:89. doi: 10.1186/1756-8722-6-89.

15.

T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.

Martinez-Forero I, Azpilikueta A, Bolaños-Mateo E, Nistal-Villan E, Palazon A, Teijeira A, Perez-Chacon G, Morales-Kastresana A, Murillo O, Jure-Kunkel M, Zapata JM, Melero I.

J Immunol. 2013 Jun 15;190(12):6694-706. doi: 10.4049/jimmunol.1203010. Epub 2013 May 20.

16.

Looking for Arabidopsis thaliana peroxidases involved in lignin biosynthesis.

Herrero J, Esteban-Carrasco A, Zapata JM.

Plant Physiol Biochem. 2013 Jun;67:77-86. doi: 10.1016/j.plaphy.2013.02.019. Epub 2013 Mar 15.

PMID:
23545205
17.

Bioinformatic and functional characterization of the basic peroxidase 72 from Arabidopsis thaliana involved in lignin biosynthesis.

Herrero J, Fernández-Pérez F, Yebra T, Novo-Uzal E, Pomar F, Pedreño MÁ, Cuello J, Guéra A, Esteban-Carrasco A, Zapata JM.

Planta. 2013 Jun;237(6):1599-612. doi: 10.1007/s00425-013-1865-5. Epub 2013 Mar 19.

PMID:
23508663
18.

TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.

Pérez-Chacón G, Llobet D, Pardo C, Pindado J, Choi Y, Reed JC, Zapata JM.

J Immunol. 2012 Jul 15;189(2):1053-61. doi: 10.4049/jimmunol.1200814. Epub 2012 Jun 18.

19.

The promoter region of the Zinnia elegans basic peroxidase isoenzyme gene contains cis-elements responsive to nitric oxide and hydrogen peroxide.

Gómez-Ros LV, Gabaldón C, López Núñez-Flores MJ, Gutiérrez J, Herrero J, Zapata JM, Sottomayor M, Cuello J, Ros Barceló A.

Planta. 2012 Aug;236(2):327-42. doi: 10.1007/s00425-012-1604-3. Epub 2012 Feb 24.

PMID:
22362137
20.

Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.

Cuesta-Mateos C, López-Giral S, Alfonso-Pérez M, de Soria VG, Loscertales J, Guasch-Vidal S, Beltrán AE, Zapata JM, Muñoz-Calleja C.

Exp Hematol. 2010 Sep;38(9):756-64, 764.e1-4. doi: 10.1016/j.exphem.2010.05.003. Epub 2010 May 19.

21.

Dehydration rate and time of desiccation affect recovery of the lichen alga [corrected] Trebouxia erici: alternative and classical protective mechanisms.

Gasulla F, de Nova PG, Esteban-Carrasco A, Zapata JM, Barreno E, Guéra A.

Planta. 2009 Dec;231(1):195-208. doi: 10.1007/s00425-009-1019-y. Epub 2009 Sep 23. Erratum in: Planta. 2009 Dec;231(1):209-10.

PMID:
19774392
22.

Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer.

Zapata JM, Llobet D, Krajewska M, Lefebvre S, Kress CL, Reed JC.

Blood. 2009 May 7;113(19):4595-603. doi: 10.1182/blood-2008-07-165456. Epub 2008 Dec 12.

23.

Targeting TRAfs for therapeutic intervention.

Zapata JM, Lefebvre S, Reed JC.

Adv Exp Med Biol. 2007;597:188-201. Review.

PMID:
17633027
24.

Phylogeny of the TRAF/MATH domain.

Zapata JM, Martínez-García V, Lefebvre S.

Adv Exp Med Biol. 2007;597:1-24. Review.

PMID:
17633013
25.

Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.

Kress CL, Konopleva M, Martínez-García V, Krajewska M, Lefebvre S, Hyer ML, McQueen T, Andreeff M, Reed JC, Zapata JM.

PLoS One. 2007 Jun 27;2(6):e559.

26.

Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.

Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6371-6. Epub 2007 Apr 2.

27.

Inactivation of a plastid evolutionary conserved gene affects PSII electron transport, life span and fitness of tobacco plants.

Zapata JM, Gasulla F, Esteban-Carrasco A, Barreno E, Guéra A.

New Phytol. 2007;174(2):357-66.

28.

Mice lacking bi-1 gene show accelerated liver regeneration.

Bailly-Maitre B, Bard-Chapeau E, Luciano F, Droin N, Bruey JM, Faustin B, Kress C, Zapata JM, Reed JC.

Cancer Res. 2007 Feb 15;67(4):1442-50.

29.

Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.

Bailly-Maitre B, Fondevila C, Kaldas F, Droin N, Luciano F, Ricci JE, Croxton R, Krajewska M, Zapata JM, Kupiec-Weglinski JW, Farmer D, Reed JC.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2809-14. Epub 2006 Feb 14.

30.

Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.

Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa S.

Immunity. 2006 Jan;24(1):29-39.

31.
32.

Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.

Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC.

Cancer Res. 2005 Jun 1;65(11):4799-808.

33.

Chloroplasts regulate leaf senescence: delayed senescence in transgenic ndhF-defective tobacco.

Zapata JM, Guéra A, Esteban-Carrasco A, Martín M, Sabater B.

Cell Death Differ. 2005 Oct;12(10):1277-84.

34.

cIAP1 Localizes to the nuclear compartment and modulates the cell cycle.

Samuel T, Okada K, Hyer M, Welsh K, Zapata JM, Reed JC.

Cancer Res. 2005 Jan 1;65(1):210-8.

35.

TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice.

Zapata JM, Krajewska M, Morse HC 3rd, Choi Y, Reed JC.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16600-5. Epub 2004 Nov 15.

36.

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.

Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, Zapata JM, Yang Y, Lee JD.

Mol Cell Biol. 2004 Mar;24(6):2226-36.

37.

Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells.

Pedersen IM, Zapata JM, Samuel T, Scott FL, Salvesen GS, Honda T, Gribble GW, Suh N, Sporn MB, Kipps TJ, Reed JC.

Blood. 2004 Aug 15;104(4):932. Epub 2004 Jan 22. No abstract available.

PMID:
14739219
38.

BAG1 over-expression in brain protects against stroke.

Kermer P, Digicaylioglu MH, Kaul M, Zapata JM, Krajewska M, Stenner-Liewen F, Takayama S, Krajewski S, Lipton SA, Reed JC.

Brain Pathol. 2003 Oct;13(4):495-506.

PMID:
14655755
39.

Comparative analysis of apoptosis and inflammation genes of mice and humans.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A; RIKEN GER Group; GSL Members.

Genome Res. 2003 Jun;13(6B):1376-88.

40.

TNF-receptor-associated factors as targets for drug development.

Zapata JM.

Expert Opin Ther Targets. 2003 Jun;7(3):411-25. Review.

PMID:
12783577
41.

The bioenergetic signature of cancer: a marker of tumor progression.

Cuezva JM, Krajewska M, de Heredia ML, Krajewski S, Santamaría G, Kim H, Zapata JM, Marusawa H, Chamorro M, Reed JC.

Cancer Res. 2002 Nov 15;62(22):6674-81.

42.

The triterpenoid CDDO induces apoptosis in refractory CLL B cells.

Pedersen IM, Kitada S, Schimmer A, Kim Y, Zapata JM, Charboneau L, Rassenti L, Andreeff M, Bennett F, Sporn MB, Liotta LD, Kipps TJ, Reed JC.

Blood. 2002 Oct 15;100(8):2965-72.

PMID:
12351409
43.

Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1.

Pedersen IM, Kitada S, Leoni LM, Zapata JM, Karras JG, Tsukada N, Kipps TJ, Choi YS, Bennett F, Reed JC.

Blood. 2002 Sep 1;100(5):1795-801.

PMID:
12176902
44.

TRAF1: lord without a RING.

Zapata JM, Reed JC.

Sci STKE. 2002 May 21;2002(133):pe27. Review.

PMID:
12023442
45.

Bag1 is a regulator and marker of neuronal differentiation.

Kermer P, Krajewska M, Zapata JM, Takayama S, Mai J, Krajewski S, Reed JC.

Cell Death Differ. 2002 Apr;9(4):405-13.

46.

Expression of Bcl-2 family member Bid in normal and malignant tissues.

Krajewska M, Zapata JM, Meinhold-Heerlein I, Hedayat H, Monks A, Bettendorf H, Shabaik A, Bubendorf L, Kallioniemi OP, Kim H, Reifenberger G, Reed JC, Krajewski S.

Neoplasia. 2002 Mar-Apr;4(2):129-40.

47.

Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system.

Krajewska M, Mai JK, Zapata JM, Ashwell KW, Schendel SL, Reed JC, Krajewski S.

Cell Death Differ. 2002 Feb;9(2):145-57.

48.

CADD, a Chlamydia protein that interacts with death receptors.

Stenner-Liewen F, Liewen H, Zapata JM, Pawlowski K, Godzik A, Reed JC.

J Biol Chem. 2002 Mar 22;277(12):9633-6. Epub 2002 Jan 22.

49.

Dynamics of glyphosate and aminomethylphosphonic acid in a forest soil in Galicia, north-west Spain.

Veiga F, Zapata JM, Fernandez Marcos ML, Alvarez E.

Sci Total Environ. 2001 Apr 23;271(1-3):135-44.

PMID:
11346036
50.

Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer.

Meinhold-Heerlein I, Stenner-Liewen F, Liewen H, Kitada S, Krajewska M, Krajewski S, Zapata JM, Monks A, Scudiero DA, Bauknecht T, Reed JC.

Am J Pathol. 2001 Apr;158(4):1335-44.

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