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Items: 1 to 50 of 80

1.

Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses.

Izzo A, Manco R, de Cristofaro T, Bonfiglio F, Cicatiello R, Mollo N, De Martino M, Genesio R, Zannini M, Conti A, Nitsch L.

Int J Genomics. 2017;2017:8737649. doi: 10.1155/2017/8737649. Epub 2017 Sep 5.

2.

The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.

Vessichelli M, Mariggiò S, Varone A, Zizza P, Di Santo A, Amore C, Dell'Elba G, Cutignano A, Fontana A, Cacciapuoti C, Di Costanzo G, Zannini M, de Cristofaro T, Evangelista V, Corda D.

J Biol Chem. 2017 Aug 4;292(31):12828-12841. doi: 10.1074/jbc.M116.773861. Epub 2017 Jun 9.

3.

Erratum to: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.

Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Calì G, Amendola E, Sanges R, Zannini M, Scarfò M, De Luca P, Nitsch L, Di Lauro R, De Felice M.

BMC Dev Biol. 2016 Aug 23;16(1):29. No abstract available.

4.

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma.

de Cristofaro T, Di Palma T, Soriano AA, Monticelli A, Affinito O, Cocozza S, Zannini M.

Oncotarget. 2016 Jul 5;7(27):41929-41947. doi: 10.18632/oncotarget.9740.

5.

NF-κB Essential Modulator (NEMO) Is Critical for Thyroid Function.

Reale C, Iervolino A, Scudiero I, Ferravante A, D'Andrea LE, Mazzone P, Zotti T, Leonardi A, Roberto L, Zannini M, de Cristofaro T, Shanmugakonar M, Capasso G, Pasparakis M, Vito P, Stilo R.

J Biol Chem. 2016 Mar 11;291(11):5765-73. doi: 10.1074/jbc.M115.711697. Epub 2016 Jan 19.

6.

Thyroid development in zebrafish lacking Taz.

Pappalardo A, Porreca I, Caputi L, De Felice E, Schulte-Merker S, Zannini M, Sordino P.

Mech Dev. 2015 Nov;138 Pt 3:268-78. doi: 10.1016/j.mod.2015.10.002. Epub 2015 Oct 22.

7.

Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells.

Lucci V, Di Palma T, Zannini M.

PLoS One. 2015 Jun 1;10(6):e0128315. doi: 10.1371/journal.pone.0128315. eCollection 2015.

8.

Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells.

Filippone MG, Di Palma T, Lucci V, Zannini M.

BMC Mol Biol. 2014 Sep 30;15:21. doi: 10.1186/1471-2199-15-21.

9.

A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells.

Di Palma T, Lucci V, de Cristofaro T, Filippone MG, Zannini M.

BMC Cancer. 2014 Apr 26;14:292. doi: 10.1186/1471-2407-14-292.

10.

NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome.

Izzo A, Manco R, Bonfiglio F, Calì G, De Cristofaro T, Patergnani S, Cicatiello R, Scrima R, Zannini M, Pinton P, Conti A, Nitsch L.

Hum Mol Genet. 2014 Aug 15;23(16):4406-19. doi: 10.1093/hmg/ddu157. Epub 2014 Apr 3.

PMID:
24698981
11.

AMOTL2 interaction with TAZ causes the inhibition of surfactant proteins expression in lung cells.

Lucci V, Di Palma T, D'Ambrosio C, Scaloni A, Zannini M.

Gene. 2013 Oct 25;529(2):300-6. doi: 10.1016/j.gene.2013.07.015. Epub 2013 Jul 31.

PMID:
23911299
12.

Pax8 has a critical role in epithelial cell survival and proliferation.

Di Palma T, Filippone MG, Pierantoni GM, Fusco A, Soddu S, Zannini M.

Cell Death Dis. 2013 Jul 18;4:e729. doi: 10.1038/cddis.2013.262.

13.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

14.

An essential role for Pax8 in the transcriptional regulation of cadherin-16 in thyroid cells.

de Cristofaro T, Di Palma T, Fichera I, Lucci V, Parrillo L, De Felice M, Zannini M.

Mol Endocrinol. 2012 Jan;26(1):67-78. doi: 10.1210/me.2011-1090. Epub 2011 Dec 1.

15.

Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis.

Di Palma T, Conti A, de Cristofaro T, Scala S, Nitsch L, Zannini M.

PLoS One. 2011;6(9):e25162. doi: 10.1371/journal.pone.0025162. Epub 2011 Sep 23.

16.

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.

Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Calì G, Amendola E, Sanges R, Zannini M, Scarfò M, De Luca P, Nitsch L, Di Lauro R, De Felice M.

BMC Dev Biol. 2011 Feb 23;11:9. doi: 10.1186/1471-213X-11-9. Erratum in: BMC Dev Biol. 2016;16(1):29.

17.

TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma.

de Cristofaro T, Di Palma T, Ferraro A, Corrado A, Lucci V, Franco R, Fusco A, Zannini M.

Eur J Cancer. 2011 Apr;47(6):926-33. doi: 10.1016/j.ejca.2010.11.008. Epub 2010 Dec 3.

PMID:
21131195
18.

Characterization of a novel loss-of-function mutation of PAX8 associated with congenital hypothyroidism.

Di Palma T, Zampella E, Filippone MG, Macchia PE, Ris-Stalpers C, de Vroede M, Zannini M.

Clin Endocrinol (Oxf). 2010 Dec;73(6):808-14. doi: 10.1111/j.1365-2265.2010.03851.x.

PMID:
20718765
19.

Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene.

Nitsch R, Di Dato V, di Gennaro A, de Cristofaro T, Abbondante S, De Felice M, Zannini M, Di Lauro R.

BMC Genomics. 2010 May 14;11:306. doi: 10.1186/1471-2164-11-306.

20.

A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid.

Amendola E, Sanges R, Galvan A, Dathan N, Manenti G, Ferrandino G, Alvino FM, Di Palma T, Scarfò M, Zannini M, Dragani TA, De Felice M, Di Lauro R.

Endocrinology. 2010 Apr;151(4):1948-58. doi: 10.1210/en.2009-1240. Epub 2010 Feb 16.

PMID:
20160132
21.

Exercises for paretic upper limb after stroke: a combined virtual-reality and telemedicine approach.

Piron L, Turolla A, Agostini M, Zucconi C, Cortese F, Zampolini M, Zannini M, Dam M, Ventura L, Battauz M, Tonin P.

J Rehabil Med. 2009 Nov;41(12):1016-102. doi: 10.2340/16501977-0459.

22.

Mutations in TAZ/WWTR1, a co-activator of NKX2.1 and PAX8 are not a frequent cause of thyroid dysgenesis.

Ferrara AM, De Sanctis L, Rossi G, Capuano S, Del Prete G, Zampella E, Gianino P, Corrias A, Fenzi G, Zannini M, Macchia PE.

J Endocrinol Invest. 2009 Mar;32(3):238-41.

PMID:
19542741
23.

The DREAM protein is associated with thyroid enlargement and nodular development.

Rivas M, Mellström B, Torres B, Cali G, Ferrara AM, Terracciano D, Zannini M, Morreale de Escobar G, Naranjo JR.

Mol Endocrinol. 2009 Jun;23(6):862-70. doi: 10.1210/me.2008-0466. Epub 2009 Mar 19.

24.

TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation.

Di Palma T, D'Andrea B, Liguori GL, Liguoro A, de Cristofaro T, Del Prete D, Pappalardo A, Mascia A, Zannini M.

Exp Cell Res. 2009 Jan 15;315(2):162-75. doi: 10.1016/j.yexcr.2008.10.016. Epub 2008 Oct 28.

PMID:
19010321
25.

Pax8 protein stability is controlled by sumoylation.

de Cristofaro T, Mascia A, Pappalardo A, D'Andrea B, Nitsch L, Zannini M.

J Mol Endocrinol. 2009 Jan;42(1):35-46. doi: 10.1677/JME-08-0100. Epub 2008 Oct 30.

PMID:
18974227
26.

Poly(ADP-ribose) polymerase 1 binds to Pax8 and inhibits its transcriptional activity.

Di Palma T, de Cristofaro T, D'Ambrosio C, Del Prete D, Scaloni A, Zannini M.

J Mol Endocrinol. 2008 Nov;41(5):379-88. doi: 10.1677/JME-08-0056. Epub 2008 Sep 3.

PMID:
18768662
27.

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy.

Conti A, Fabbrini F, D'Agostino P, Negri R, Greco D, Genesio R, D'Armiento M, Olla C, Paladini D, Zannini M, Nitsch L.

BMC Genomics. 2007 Aug 7;8:268.

28.

Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation.

Calì G, Zannini M, Rubini P, Tacchetti C, D'Andrea B, Affuso A, Wintermantel T, Boussadia O, Terracciano D, Silberschmidt D, Amendola E, De Felice M, Schütz G, Kemler R, Di Lauro R, Nitsch L.

Endocrinology. 2007 Jun;148(6):2737-46. Epub 2007 Mar 8.

PMID:
17347311
29.

Optic nerve structure in healthy subjects.

Savini G, Zanini M, Carelli V, Sadun AA, Ross-Cisneros FN, Barboni P.

Arch Ophthalmol. 2006 Oct;124(10):1507; author reply 1508-9. No abstract available. Erratum in: Arch Ophthalmol. 2006 Dec;124(12):1700. Zannini, Maurizio [corrected to Zanini, Maurizio].

PMID:
17030731
30.

Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction.

D'Andrea B, Iacone R, Di Palma T, Nitsch R, Baratta MG, Nitsch L, Di Lauro R, Zannini M.

Mol Endocrinol. 2006 Aug;20(8):1810-24. Epub 2006 Apr 13.

PMID:
16613988
31.

An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer.

Antonini D, Rossi B, Han R, Minichiello A, Di Palma T, Corrado M, Banfi S, Zannini M, Brissette JL, Missero C.

Mol Cell Biol. 2006 Apr;26(8):3308-18.

32.

Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells.

Dentice M, Luongo C, Elefante A, Ambrosio R, Salzano S, Zannini M, Nitsch R, Di Lauro R, Rossi G, Fenzi G, Salvatore D.

Mol Cell Biol. 2005 Nov;25(22):10171-82.

33.

The transcriptional repressor DREAM is involved in thyroid gene expression.

D'Andrea B, Di Palma T, Mascia A, Motti ML, Viglietto G, Nitsch L, Zannini M.

Exp Cell Res. 2005 Apr 15;305(1):166-78.

PMID:
15777797
34.

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease.

Garcia-Barcelo M, Ganster RW, Lui VC, Leon TY, So MT, Lau AM, Fu M, Sham MH, Knight J, Zannini MS, Sham PC, Tam PK.

Hum Mol Genet. 2005 Jan 15;14(2):191-204. Epub 2004 Nov 17.

PMID:
15548547
35.

Familial PAX8 small deletion (c.989_992delACCC) associated with extreme phenotype variability.

de Sanctis L, Corrias A, Romagnolo D, Di Palma T, Biava A, Borgarello G, Gianino P, Silvestro L, Zannini M, Dianzani I.

J Clin Endocrinol Metab. 2004 Nov;89(11):5669-74.

PMID:
15531527
37.

TAZ interacts with TTF-1 and regulates expression of surfactant protein-C.

Park KS, Whitsett JA, Di Palma T, Hong JH, Yaffe MB, Zannini M.

J Biol Chem. 2004 Apr 23;279(17):17384-90. Epub 2004 Feb 17.

38.

WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8.

Nitsch R, Di Palma T, Mascia A, Zannini M.

Biochem J. 2004 Feb 1;377(Pt 3):553-60.

39.

The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription.

Di Palma T, Nitsch R, Mascia A, Nitsch L, Di Lauro R, Zannini M.

J Biol Chem. 2003 Jan 31;278(5):3395-402. Epub 2002 Nov 18.

40.

Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland.

Postiglione MP, Parlato R, Rodriguez-Mallon A, Rosica A, Mithbaokar P, Maresca M, Marians RC, Davies TF, Zannini MS, De Felice M, Di Lauro R.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15462-7. Epub 2002 Nov 13.

41.
42.

Pax8 has a key role in thyroid cell differentiation.

Pasca di Magliano M, Di Lauro R, Zannini M.

Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13144-9.

43.

Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation.

Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Barone MV, Ametrano D, Zannini MS, Abbondanza C, Auricchio F.

EMBO J. 2000 Oct 16;19(20):5406-17.

44.

The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor.

Perrone L, Pasca di Magliano M, Zannini M, Di Lauro R.

Biochem Biophys Res Commun. 2000 Aug 18;275(1):203-8.

PMID:
10944465
45.

Akt/protein kinase B promotes survival and hormone-independent proliferation of thyroid cells in the absence of dedifferentiating and transforming effects.

De Vita G, Berlingieri MT, Visconti R, Castellone MD, Viglietto G, Baldassarre G, Zannini M, Bellacosa A, Tsichlis PN, Fusco A, Santoro M.

Cancer Res. 2000 Jul 15;60(14):3916-20.

47.

RhoA activity is required for fibronectin assembly and counteracts beta1B integrin inhibitory effect in FRT epithelial cells.

Calì G, Mazzarella C, Chiacchio M, Negri R, Retta SF, Zannini M, Gentile F, Tarone G, Nitsch L, Garbi C.

J Cell Sci. 1999 Mar;112 ( Pt 6):957-65.

49.

p53 genes mutated in the DNA binding site or at a specific COOH-terminal site exert divergent effects on thyroid cell growth and differentiation.

Casamassimi A, Miano MG, Porcellini A, De Vita G, de Nigris F, Zannini M, Di Lauro R, Russo T, Avvedimento VE, Fusco A.

Cancer Res. 1998 Jul 1;58(13):2888-94.

50.

Ha-ras interference with thyroid cell differentiation is associated with a down-regulation of thyroid transcription factor-1 phosphorylation.

Velasco JA, Acebrón A, Zannini M, Martín-Pérez J, Di Lauro R, Santisteban P.

Endocrinology. 1998 Jun;139(6):2796-802.

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