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Items: 25


Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.

Ainouze M, Rochefort P, Parroche P, Roblot G, Tout I, Briat F, Zannetti C, Marotel M, Goutagny N, Auron P, Traverse-Glehen A, Lunel-Potencier A, Golfier F, Masson M, Robitaille A, Tommasino M, Carreira C, Walzer T, Henry T, Zanier K, Trave G, Hasan UA.

PLoS Pathog. 2018 Aug 8;14(8):e1007158. doi: 10.1371/journal.ppat.1007158. eCollection 2018 Aug.


Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

Poirson J, Biquand E, Straub ML, Cassonnet P, Nominé Y, Jones L, van der Werf S, Travé G, Zanier K, Jacob Y, Demeret C, Masson M.

FEBS J. 2017 Oct;284(19):3171-3201. doi: 10.1111/febs.14193. Epub 2017 Aug 29.


Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.

Voith von Voithenberg L, Sánchez-Rico C, Kang HS, Madl T, Zanier K, Barth A, Warner LR, Sattler M, Lamb DC.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7169-E7175. Epub 2016 Oct 31.


HPV-mediated inactivation of tumor suppressor p53.

Travé G, Zanier K.

Cell Cycle. 2016 Sep;15(17):2231-2. doi: 10.1080/15384101.2016.1191257. Epub 2016 May 31. No abstract available.


Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.

Martinez-Zapien D, Ruiz FX, Poirson J, Mitschler A, Ramirez J, Forster A, Cousido-Siah A, Masson M, Vande Pol S, Podjarny A, Travé G, Zanier K.

Nature. 2016 Jan 28;529(7587):541-5. doi: 10.1038/nature16481. Epub 2016 Jan 20.


Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides.

Stutz C, Reinz E, Honegger A, Bulkescher J, Schweizer J, Zanier K, Travé G, Lohrey C, Hoppe-Seyler K, Hoppe-Seyler F.

PLoS One. 2015 Jul 7;10(7):e0132339. doi: 10.1371/journal.pone.0132339. eCollection 2015.


The E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6.

Zanier K, Stutz C, Kintscher S, Reinz E, Sehr P, Bulkescher J, Hoppe-Seyler K, Travé G, Hoppe-Seyler F.

PLoS One. 2014 Nov 10;9(11):e112514. doi: 10.1371/journal.pone.0112514. eCollection 2014.


Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.

Zanier K, Charbonnier S, Sidi AO, McEwen AG, Ferrario MG, Poussin-Courmontagne P, Cura V, Brimer N, Babah KO, Ansari T, Muller I, Stote RH, Cavarelli J, Vande Pol S, Travé G.

Science. 2013 Feb 8;339(6120):694-8. doi: 10.1126/science.1229934.


Solution structure analysis of the HPV16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53.

Zanier K, ould M'hamed ould Sidi A, Boulade-Ladame C, Rybin V, Chappelle A, Atkinson A, Kieffer B, Travé G.

Structure. 2012 Apr 4;20(4):604-17. doi: 10.1016/j.str.2012.02.001. Epub 2012 Apr 3.


Strategies for bacterial expression of protein-peptide complexes: application to solubilization of papillomavirus E6.

Sidi AO, Babah KO, Brimer N, Nominé Y, Romier C, Kieffer B, Pol SV, Travé G, Zanier K.

Protein Expr Purif. 2011 Nov;80(1):8-16. doi: 10.1016/j.pep.2011.06.013. Epub 2011 Jul 14.


Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M.

Nature. 2011 Jul 13;475(7356):408-11. doi: 10.1038/nature10171.


E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo.

Zanier K, Ruhlmann C, Melin F, Masson M, Ould M'hamed Ould Sidi A, Bernard X, Fischer B, Brino L, Ristriani T, Rybin V, Baltzinger M, Vande Pol S, Hellwig P, Schultz P, Travé G.

J Mol Biol. 2010 Feb 12;396(1):90-104. doi: 10.1016/j.jmb.2009.11.022. Epub 2009 Nov 13.


Identification of unusual E6 and E7 proteins within avian papillomaviruses: cellular localization, biophysical characterization, and phylogenetic analysis.

Van Doorslaer K, Sidi AO, Zanier K, Rybin V, Deryckère F, Rector A, Burk RD, Lienau EK, van Ranst M, Travé G.

J Virol. 2009 Sep;83(17):8759-70. doi: 10.1128/JVI.01777-08. Epub 2009 Jun 24.


A NMR strategy to unambiguously distinguish nucleic acid hairpin and duplex conformations applied to a Xist RNA A-repeat.

Duszczyk MM, Zanier K, Sattler M.

Nucleic Acids Res. 2008 Dec;36(22):7068-77. doi: 10.1093/nar/gkn776. Epub 2008 Nov 5.


Formation of well-defined soluble aggregates upon fusion to MBP is a generic property of E6 proteins from various human papillomavirus species.

Zanier K, Nominé Y, Charbonnier S, Ruhlmann C, Schultz P, Schweizer J, Travé G.

Protein Expr Purif. 2007 Jan;51(1):59-70. Epub 2006 Sep 9.


Capturing protein-protein complexes at equilibrium: the holdup comparative chromatographic retention assay.

Charbonnier S, Zanier K, Masson M, Travé G.

Protein Expr Purif. 2006 Nov;50(1):89-101. Epub 2006 Jun 27.


Intron removal requires proofreading of U2AF/3' splice site recognition by DEK.

Soares LM, Zanier K, Mackereth C, Sattler M, Valcárcel J.

Science. 2006 Jun 30;312(5782):1961-5.


The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif.

Lescrinier E, Nauwelaerts K, Zanier K, Poesen K, Sattler M, Herdewijn P.

Nucleic Acids Res. 2006 May 31;34(10):2878-86. Print 2006.


Chemical shift backbone assignments of TAP-N, the 31 kDa cargo-binding region of the protein TAP.

Pimienta G, Gabel F, Zanier K, Conti E, Sattler M.

J Biomol NMR. 2006;36 Suppl 1:23. No abstract available.


Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis.

Nominé Y, Masson M, Charbonnier S, Zanier K, Ristriani T, Deryckère F, Sibler AP, Desplancq D, Atkinson RA, Weiss E, Orfanoudakis G, Kieffer B, Travé G.

Mol Cell. 2006 Mar 3;21(5):665-78.


Kinetic analysis of the interactions of human papillomavirus E6 oncoproteins with the ubiquitin ligase E6AP using surface plasmon resonance.

Zanier K, Charbonnier S, Baltzinger M, Nominé Y, Altschuh D, Travé G.

J Mol Biol. 2005 Jun 3;349(2):401-12. Epub 2005 Apr 9.


Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6.

Lagrange M, Charbonnier S, Orfanoudakis G, Robinson P, Zanier K, Masson M, Lutz Y, Trave G, Weiss E, Deryckere F.

J Gen Virol. 2005 Apr;86(Pt 4):1001-7.


Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.

Zanier K, Luyten I, Crombie C, Muller B, Schümperli D, Linge JP, Nilges M, Sattler M.

RNA. 2002 Jan;8(1):29-46.


Structural basis for recognition of the intron branch site RNA by splicing factor 1.

Liu Z, Luyten I, Bottomley MJ, Messias AC, Houngninou-Molango S, Sprangers R, Zanier K, Krämer A, Sattler M.

Science. 2001 Nov 2;294(5544):1098-102.


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