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Items: 38

1.

Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation.

Marampon F, Ciccarelli C, Zani BM.

Int J Mol Sci. 2019 May 23;20(10). pii: E2530. doi: 10.3390/ijms20102530. Review.

2.

Disruption of MEK/ERK/c-Myc signaling radiosensitizes prostate cancer cells in vitro and in vivo.

Ciccarelli C, Di Rocco A, Gravina GL, Mauro A, Festuccia C, Del Fattore A, Berardinelli P, De Felice F, Musio D, Bouché M, Tombolini V, Zani BM, Marampon F.

J Cancer Res Clin Oncol. 2018 Sep;144(9):1685-1699. doi: 10.1007/s00432-018-2696-3. Epub 2018 Jun 29.

PMID:
29959569
3.

Testosterone-mediated activation of androgenic signalling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines.

Giannattasio S, Megiorni F, Di Nisio V, Del Fattore A, Fontanella R, Camero S, Antinozzi C, Festuccia C, Gravina GL, Cecconi S, Dominici C, Di Luigi L, Ciccarelli C, De Cesaris P, Riccioli A, Zani BM, Lenzi A, Pestell RG, Filippini A, Crescioli C, Tombolini V, Marampon F.

J Endocrinol Invest. 2019 Feb;42(2):183-197. doi: 10.1007/s40618-018-0900-6. Epub 2018 May 22.

PMID:
29790086
4.

Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population.

Ciccarelli C, Vulcano F, Milazzo L, Gravina GL, Marampon F, Macioce G, Giampaolo A, Tombolini V, Di Paolo V, Hassan HJ, Zani BM.

Mol Cancer. 2016 Feb 20;15:16. doi: 10.1186/s12943-016-0501-y.

5.

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay.

Marampon F, Gravina GL, Zani BM, Popov VM, Fratticci A, Cerasani M, Di Genova D, Mancini M, Ciccarelli C, Ficorella C, Di Cesare E, Festuccia C.

Int J Oncol. 2014 Jun;44(6):2121-31. doi: 10.3892/ijo.2014.2358. Epub 2014 Mar 24.

PMID:
24676782
6.

Nitric oxide synthase inhibition reverts muscarinic receptor down-regulation induced by pilocarpine- and kainic acid-evoked seizures in rat fronto-parietal cortex.

Capannolo M, Ciccarelli C, Molteni R, Fumagalli F, Rocchi C, Romeo S, Fasciani I, Aloisi G, Zani BM, Riva MA, Maggio R.

Epilepsy Res. 2014 Jan;108(1):11-9. doi: 10.1016/j.eplepsyres.2013.10.011. Epub 2013 Oct 28.

PMID:
24246145
7.

Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines.

Marampon F, Gravina GL, Popov VM, Scarsella L, Festuccia C, La Verghetta ME, Parente S, Cerasani M, Bruera G, Ficorella C, Ricevuto E, Tombolini V, Di Cesare E, Zani BM.

Int J Oncol. 2014 Jan;44(1):285-94. doi: 10.3892/ijo.2013.2167. Epub 2013 Nov 5.

PMID:
24189697
8.

Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis.

Marampon F, Gravina GL, Scarsella L, Festuccia C, Lovat F, Ciccarelli C, Zani BM, Polidoro L, Grassi D, Desideri G, Evangelista S, Ferri C.

J Hypertens. 2013 Oct;31(10):1972-83. doi: 10.1097/HJH.0b013e3283638b32.

PMID:
23868084
9.

Vitamin D protects human endothelial cells from H₂O₂ oxidant injury through the Mek/Erk-Sirt1 axis activation.

Polidoro L, Properzi G, Marampon F, Gravina GL, Festuccia C, Di Cesare E, Scarsella L, Ciccarelli C, Zani BM, Ferri C.

J Cardiovasc Transl Res. 2013 Apr;6(2):221-31. doi: 10.1007/s12265-012-9436-x. Epub 2012 Dec 18.

PMID:
23247634
10.

Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models.

Gravina GL, Marampon F, Piccolella M, Motta M, Ventura L, Pomante R, Popov VM, Zani BM, Pestell RG, Tombolini V, Jannini EA, Festuccia C.

Endocrinology. 2011 Dec;152(12):4550-61. doi: 10.1210/en.2011-1056. Epub 2011 Oct 11.

11.

MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals.

Marampon F, Gravina GL, Di Rocco A, Bonfili P, Di Staso M, Fardella C, Polidoro L, Ciccarelli C, Festuccia C, Popov VM, Pestell RG, Tombolini V, Zani BM.

Mol Cancer Ther. 2011 Jan;10(1):159-68. doi: 10.1158/1535-7163.MCT-10-0631.

12.

Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation.

Gravina GL, Festuccia C, Marampon F, Popov VM, Pestell RG, Zani BM, Tombolini V.

Mol Cancer. 2010 Nov 25;9:305. doi: 10.1186/1476-4598-9-305. Review.

13.

MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

Marampon F, Bossi G, Ciccarelli C, Di Rocco A, Sacchi A, Pestell RG, Zani BM.

Mol Cancer Ther. 2009 Mar;8(3):543-51. doi: 10.1158/1535-7163.MCT-08-0570. Epub 2009 Mar 3.

14.

Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB.

Marampon F, Casimiro MC, Fu M, Powell MJ, Popov VM, Lindsay J, Zani BM, Ciccarelli C, Watanabe G, Lee RJ, Pestell RG.

Mol Biol Cell. 2008 Jun;19(6):2566-78. doi: 10.1091/mbc.E06-12-1110. Epub 2008 Mar 26.

15.

ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program.

Pelosi M, Marampon F, Zani BM, Prudente S, Perlas E, Caputo V, Cianetti L, Berno V, Narumiya S, Kang SW, Musarò A, Rosenthal N.

Mol Cell Biol. 2007 Sep;27(17):6163-76. Epub 2007 Jul 2.

17.

HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers.

Vulcano F, Ciccarelli C, Mattia G, Marampon F, Giampiero M, Milazzo L, Pascuccio M, Zani BM, Giampaolo A, Hassan HJ.

Exp Cell Res. 2006 May 15;312(9):1590-7.

PMID:
16739251
18.
19.

PKCalpha-mediated ERK, JNK and p38 activation regulates the myogenic program in human rhabdomyosarcoma cells.

Mauro A, Ciccarelli C, De Cesaris P, Scoglio A, Bouché M, Molinaro M, Aquino A, Zani BM.

J Cell Sci. 2002 Sep 15;115(Pt 18):3587-99.

20.
21.

Enhanced expression of myogenic regulatory genes in aging skeletal muscle.

Musarò A, Cusella De Angelis MG, Germani A, Ciccarelli C, Molinaro M, Zani BM.

Exp Cell Res. 1995 Nov;221(1):241-8.

PMID:
7589251
22.
23.

TPA-induced differentiation of human rhabdomyosarcoma cells involves dephosphorylation and nuclear accumulation of mutant P53.

Germani A, Fusco C, Martinotti S, Musarò A, Molinaro M, Zani BM.

Biochem Biophys Res Commun. 1994 Jul 15;202(1):17-24.

PMID:
8037710
24.

Paracrine stimulation of senescent satellite cell proliferation by factors released by muscle or myotubes from young mice.

Mezzogiorno A, Coletta M, Zani BM, Cossu G, Molinaro M.

Mech Ageing Dev. 1993 Aug 1;70(1-2):35-44.

PMID:
8231287
25.

Spontaneous channel activity induced by tumor promoter TPA in chick myotubes.

Ciccarelli C, Zani BM, Molinaro M, Grassi F, Eusebi F.

Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug;338(2):121-4.

PMID:
2460773
26.

Tumor promotion and signal transduction mechanisms.

Zani BM, Adamo S, Molinaro M.

Ann Ist Super Sanita. 1988;24(1):179-98. Review. No abstract available.

PMID:
3289439
27.

Microwave effects on acetylcholine-induced channels in cultured chick myotubes.

D'Inzeo G, Bernardi P, Eusebi F, Grassi F, Tamburello C, Zani BM.

Bioelectromagnetics. 1988;9(4):363-72.

PMID:
2461204
28.

Membrane molecules involved in adhesion properties of cultured Sertoli cells.

Zani BM, Ziparo E, Russo MA, Filippini A, Stefanini M.

Gamete Res. 1987 Dec;18(4):301-10.

PMID:
3333758
29.
30.

Acetylcholine may regulate its own nicotinic receptor-channel through the C-kinase system.

Eusebi F, Grassi F, Nervi C, Caporale C, Adamo S, Zani BM, Molinaro M.

Proc R Soc Lond B Biol Sci. 1987 Apr 22;230(1260):355-65.

PMID:
2884674
31.

Proteins of the membrane skeleton in rat Sertoli cells.

Ziparo E, Zani BM, Filippini A, Stefanini M, Marchesi VT.

J Cell Sci. 1986 Dec;86:145-54.

32.

Cyclic AMP regulates the life time of acetylcholine-activated channels in cultured myotubes.

Zani BM, Grassi F, Molinaro M, Monaco L, Eusebi F.

Biochem Biophys Res Commun. 1986 Oct 15;140(1):243-9.

PMID:
2430564
33.

Acetylcholine stimulates phosphatidylinositol turnover at nicotinic receptors of cultured myotubes.

Adamo S, Zani BM, Nervi C, Senni MI, Molinaro M, Eusebi F.

FEBS Lett. 1985 Oct 7;190(1):161-4.

34.
36.

Changes of Sertoli cell glycoproteins induced by removal of the associated germ cells.

Galdieri M, Zani BM, Monaco L, Ziparo E, Stefanini M.

Exp Cell Res. 1983 Apr 15;145(1):191-8.

PMID:
6303818
37.

PMA-induced biosynthetic changes in differentiating muscle cells in culture.

Zani BM, Molinaro M.

Cell Biol Int Rep. 1982 Apr;6(4):340. No abstract available.

PMID:
7094023
38.

Early alteration induced by tumor promoters on chick embryo muscle cells in culture.

Zani BM, Molinaro M.

Prog Clin Biol Res. 1982;85 Pt B:403-14.

PMID:
7122574

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