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Items: 1 to 50 of 137

1.

In vivo growth of 60 non-screening detected lung cancers: a computed tomography study.

Mets OM, Chung K, Zanen P, Scholten ET, Veldhuis WB, van Ginneken B, Prokop M, Schaefer-Prokop CM, de Jong PA.

Eur Respir J. 2018 Apr 12;51(4). pii: 1702183. doi: 10.1183/13993003.02183-2017. Print 2018 Apr.

PMID:
29650547
2.

Course of SP-D, YKL-40, CCL18 and CA 15-3 in adult patients hospitalised with community-acquired pneumonia and their association with disease severity and aetiology: A post-hoc analysis.

Spoorenberg SMC, Vestjens SMT, Voorn GP, van Moorsel CHM, Meek B, Zanen P, Rijkers GT, Bos WJW, Grutters JC; Ovidius study group.

PLoS One. 2018 Jan 11;13(1):e0190575. doi: 10.1371/journal.pone.0190575. eCollection 2018.

3.

The effectiveness of a nurse-led illness perception intervention in COPD patients: a cluster randomised trial in primary care.

Weldam SWM, Schuurmans MJ, Zanen P, Heijmans MJWM, Sachs APE, Lammers JJ.

ERJ Open Res. 2017 Dec 8;3(4). pii: 00115-2016. doi: 10.1183/23120541.00115-2016. eCollection 2017 Oct.

4.

Don't Forget Symptomatic Smokers without Airflow Obstruction.

Mohamed Hoesein FAA, Zanen P.

Ann Am Thorac Soc. 2017 May;14(5):615-616. doi: 10.1513/AnnalsATS.201701-049ED. No abstract available.

PMID:
28459630
5.

Long-term Clinical Outcome of Antibody Replacement Therapy in Humoral Immunodeficient Adults With Respiratory Tract Infections.

van Kessel DA, Hoffman TW, van Velzen-Blad H, Zanen P, Grutters JC, Rijkers GT.

EBioMedicine. 2017 Apr;18:254-260. doi: 10.1016/j.ebiom.2017.03.025. Epub 2017 Mar 21.

6.

Long-term Follow-up of Humoral Immune Status in Adult Lung Transplant Recipients.

van Kessel DA, Hoffman TW, Kwakkel-van Erp JM, Oudijk ED, Zanen P, Rijkers GT, Grutters JC.

Transplantation. 2017 Oct;101(10):2477-2483. doi: 10.1097/TP.0000000000001685.

PMID:
28198768
7.

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH; COPDGene Investigators; ECLIPSE Investigators; LifeLines Investigators; SPIROMICS Research Group; International COPD Genetics Network Investigators; UK BiLEVE Investigators; International COPD Genetics Consortium.

Nat Genet. 2017 Mar;49(3):426-432. doi: 10.1038/ng.3752. Epub 2017 Feb 6.

8.

Follow-up of CT-derived airway wall thickness: Correcting for changes in inspiration level improves reliability.

Pompe E, van Rikxoort EM, Mets OM, Charbonnier JP, Kuhnigk JM, de Koning HJ, Oudkerk M, Vliegenthart R, Zanen P, Lammers JJ, van Ginneken B, de Jong PA, Mohamed Hoesein FAA.

Eur J Radiol. 2016 Nov;85(11):2008-2013. doi: 10.1016/j.ejrad.2016.09.009. Epub 2016 Sep 13.

PMID:
27776653
9.

Efficacy of an mHealth intervention to stimulate physical activity in COPD patients after pulmonary rehabilitation.

Vorrink SN, Kort HS, Troosters T, Zanen P, Lammers JJ.

Eur Respir J. 2016 Oct;48(4):1019-1029. doi: 10.1183/13993003.00083-2016. Epub 2016 Sep 1.

10.

Technology use by older adults in the Netherlands and its associations with demographics and health outcomes.

Vorrink SNW, Antonietti AMGEF, Kort HSM, Troosters T, Zanen P, Lammers JJ.

Assist Technol. 2017 Winter;29(4):188-196. doi: 10.1080/10400435.2016.1219885. Epub 2016 Aug 22.

PMID:
27548101
11.

Cystic Fibrosis-Related Diabetes with strict glycaemic control is not associated with frequent intravenous antibiotics use for pulmonary infections.

Belle-van Meerkerk G, de Valk HW, Stam-Slob MC, Teding van Berkhout F, Zanen P, van de Graaf EA.

Diabetes Res Clin Pract. 2016 Jun;116:230-6. doi: 10.1016/j.diabres.2016.04.014. Epub 2016 Apr 27.

PMID:
27321340
12.

The association between vitamin D and C-reactive protein levels in patients with inflammatory and non-inflammatory diseases.

Kruit A, Zanen P.

Clin Biochem. 2016 May;49(7-8):534-7. doi: 10.1016/j.clinbiochem.2016.01.002. Epub 2016 Jan 8.

PMID:
26778547
13.

Pulmonary function changes in Navy divers during their professional careers.

Voortman M, Ooij PJAMV, Hulst RAV, Zanen P.

Undersea Hyperb Med. 2016 Sept-Oct;43(6):649-657.

PMID:
28768392
14.

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study.

Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat M, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort Study.

PLoS One. 2015 May 29;10(5):e0129524. doi: 10.1371/journal.pone.0129524. eCollection 2015. No abstract available.

15.

Telomere length in interstitial lung diseases.

Snetselaar R, van Moorsel CHM, Kazemier KM, van der Vis JJ, Zanen P, van Oosterhout MFM, Grutters JC.

Chest. 2015 Oct;148(4):1011-1018. doi: 10.1378/chest.14-3078.

PMID:
25973743
16.

Chest Computed Tomography-Based Scoring of Thoracic Sarcoidosis: Inter-rater Reliability of CT Abnormalities.

Van den Heuvel DA, de Jong PA, Zanen P, van Es HW, van Heesewijk JP, Spee M, Grutters JC.

Eur Radiol. 2015 Sep;25(9):2558-66. doi: 10.1007/s00330-015-3685-4. Epub 2015 Apr 9.

PMID:
25854216
17.

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI, Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q; LifeLines Cohort Study, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, Vinkhuyzen AAE, Westra HJ, Zheng W, Zondervan KT; ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Heath AC, Arveiler D, Bakker SJL, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJP, Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Marchand LL, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Madden PAF, Pasterkamp G, Peden JF, Peters A, Postma DS, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Rioux JD, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schunkert H, Schwarz PEH, Sever P, Shuldiner AR, Sinisalo J, Stolk RP, Strauch K, Tönjes A, Trégouët DA, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Völker U, Waeber G, Willemsen G, Witteman JC, Zillikens MC, Adair LS, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bornstein SR, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PIW, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hui J, Hunter DJ, Hveem K, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, März W, Melbye M, Metspalu A, Moebus S, Munroe PB, Njølstad I, Oostra BA, Palmer CNA, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sattar N, Schadt EE, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Thorsteinsdottir U, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Walker M, Wallaschofski H, Wareham NJ, Watkins H, Weir DR, Wichmann HE, Wilson JF, Zanen P, Borecki IB, Deloukas P, Fox CS, Heid IM, O'Connell JR, Strachan DP, Stefansson K, van Duijn CM, Abecasis GR, Franke L, Frayling TM, McCarthy MI, Visscher PM, Scherag A, Willer CJ, Boehnke M, Mohlke KL, Lindgren CM, Beckmann JS, Barroso I, North KE, Ingelsson E, Hirschhorn JN, Loos RJF, Speliotes EK.

Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177.

18.

Airway wall thickness associated with forced expiratory volume in 1 second decline and development of airflow limitation.

Mohamed Hoesein FA, de Jong PA, Lammers JW, Mali WP, Schmidt M, de Koning HJ, van der Aalst C, Oudkerk M, Vliegenthart R, Groen HJ, van Ginneken B, van Rikxoort EM, Zanen P.

Eur Respir J. 2015 Mar;45(3):644-51. doi: 10.1183/09031936.00020714. Epub 2015 Jan 22.

19.

Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses.

Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Boezen HM, Groen HJ.

Am J Respir Crit Care Med. 2015 Mar 1;191(5):547-56. doi: 10.1164/rccm.201405-0840OC.

PMID:
25517131
20.

ACE and sIL-2R correlate with lung function improvement in sarcoidosis during methotrexate therapy.

Vorselaars AD, van Moorsel CH, Zanen P, Ruven HJ, Claessen AM, van Velzen-Blad H, Grutters JC.

Respir Med. 2015 Feb;109(2):279-85. doi: 10.1016/j.rmed.2014.11.009. Epub 2014 Nov 29.

21.

The interdependence between cardiovascular calcifications in different arterial beds and vascular risk factors in patients at high cardiovascular risk.

Takx RA, Zanen P, Leiner T, van der Graaf Y, de Jong PA; SMART study group.

Atherosclerosis. 2015 Jan;238(1):140-6. doi: 10.1016/j.atherosclerosis.2014.11.024. Epub 2014 Nov 29.

PMID:
25485737
22.

Defining the role of common variation in the genomic and biological architecture of adult human height.

Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspersen IH, Chines PS, Clarke R, Claudi-Boehm S, Cooper M, Daw EW, De Jong PA, Deelen J, Delgado G, Denny JC, Dhonukshe-Rutten R, Dimitriou M, Doney AS, Dörr M, Eklund N, Eury E, Folkersen L, Garcia ME, Geller F, Giedraitis V, Go AS, Grallert H, Grammer TB, Gräßler J, Grönberg H, de Groot LC, Groves CJ, Haessler J, Hall P, Haller T, Hallmans G, Hannemann A, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hemani G, Henders AK, Hillege HL, Hlatky MA, Hoffmann W, Hoffmann P, Holmen O, Houwing-Duistermaat JJ, Illig T, Isaacs A, James AL, Jeff J, Johansen B, Johansson Å, Jolley J, Juliusdottir T, Junttila J, Kho AN, Kinnunen L, Klopp N, Kocher T, Kratzer W, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Lu Y, Lyssenko V, Magnusson PK, Mahajan A, Maillard M, McArdle WL, McKenzie CA, McLachlan S, McLaren PJ, Menni C, Merger S, Milani L, Moayyeri A, Monda KL, Morken MA, Müller G, Müller-Nurasyid M, Musk AW, Narisu N, Nauck M, Nolte IM, Nöthen MM, Oozageer L, Pilz S, Rayner NW, Renstrom F, Robertson NR, Rose LM, Roussel R, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Schunkert H, Scott RA, Sehmi J, Seufferlein T, Shi J, Silventoinen K, Smit JH, Smith AV, Smolonska J, Stanton AV, Stirrups K, Stott DJ, Stringham HM, Sundström J, Swertz MA, Syvänen AC, Tayo BO, Thorleifsson G, Tyrer JP, van Dijk S, van Schoor NM, van der Velde N, van Heemst D, van Oort FV, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Waldenberger M, Wennauer R, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boomsma DI, Bornstein SR, Bovet P, Brambilla P, Brown MJ, Campbell H, Caulfield MJ, Chakravarti A, Collins R, Collins FS, Crawford DC, Cupples LA, Danesh J, de Faire U, den Ruijter HM, Erbel R, Erdmann J, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Gansevoort RT, Gejman PV, Gieger C, Golay A, Gottesman O, Gudnason V, Gyllensten U, Haas DW, Hall AS, Harris TB, Hattersley AT, Heath AC, Hengstenberg C, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Hovingh GK, Humphries SE, Hunt SC, Hypponen E, Jacobs KB, Jarvelin MR, Jousilahti P, Jula AM, Kaprio J, Kastelein JJ, Kayser M, Kee F, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kooner JS, Kooperberg C, Koskinen S, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lupoli S, Madden PA, Männistö S, Manunta P, Marette A, Matise TC, McKnight B, Meitinger T, Moll FL, Montgomery GW, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Ouwehand WH, Pasterkamp G, Peters A, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ritchie M, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Sebert S, Sever P, Shuldiner AR, Sinisalo J, Steinthorsdottir V, Stolk RP, Tardif JC, Tönjes A, Tremblay A, Tremoli E, Virtamo J, Vohl MC; Electronic Medical Records and Genomics (eMEMERGEGE) Consortium; MIGen Consortium; PAGEGE Consortium; LifeLines Cohort Study, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PI, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hayes MG, Hui J, Hunter DJ, Hveem K, Jukema JW, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, März W, Melbye M, Moebus S, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Powell JE, Power C, Quertermous T, Rauramaa R, Reinmaa E, Ridker PM, Rivadeneira F, Rotter JI, Saaristo TE, Saleheen D, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Strauch K, Stumvoll M, Tuomilehto J, Uusitupa M, van der Harst P, Völzke H, Walker M, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Zanen P, Deloukas P, Heid IM, Lindgren CM, Mohlke KL, Speliotes EK, Thorsteinsdottir U, Barroso I, Fox CS, North KE, Strachan DP, Beckmann JS, Berndt SI, Boehnke M, Borecki IB, McCarthy MI, Metspalu A, Stefansson K, Uitterlinden AG, van Duijn CM, Franke L, Willer CJ, Price AL, Lettre G, Loos RJ, Weedon MN, Ingelsson E, O'Connell JR, Abecasis GR, Chasman DI, Goddard ME, Visscher PM, Hirschhorn JN, Frayling TM.

Nat Genet. 2014 Nov;46(11):1173-86. doi: 10.1038/ng.3097. Epub 2014 Oct 5.

23.

Evaluation of circulating YKL-40 levels in idiopathic interstitial pneumonias.

Korthagen NM, van Moorsel CH, Zanen P, Ruven HJ, Grutters JC.

Lung. 2014 Dec;192(6):975-80. doi: 10.1007/s00408-014-9647-9. Epub 2014 Oct 2.

PMID:
25274153
24.

Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.

Dijkstra AE, Boezen HM, van den Berge M, Vonk JM, Hiemstra PS, Barr RG, Burkart KM, Manichaikul A, Pottinger TD, Silverman EK, Cho MH, Crapo JD, Beaty TH, Bakke P, Gulsvik A, Lomas DA, Bossé Y, Nickle DC, Paré PD, de Koning HJ, Lammers JW, Zanen P, Smolonska J, Wijmenga C, Brandsma CA, Groen HJ, Postma DS; LifeLines Cohort Study group.

Eur Respir J. 2015 Jan;45(1):60-75. doi: 10.1183/09031936.00093314. Epub 2014 Sep 18.

25.

Pulmonary function and CT biomarkers as risk factors for cardiovascular events in male lung cancer screening participants: the NELSON study.

Takx RA, Vliegenthart R, Mohamed Hoesein FA, Išgum I, de Koning HJ, Mali WP, van der Aalst CM, Zanen P, Lammers JW, Groen HJ, van Rikxoort EM, Schmidt M, van Ginneken B, Oudkerk M, Leiner T, de Jong PA.

Eur Radiol. 2015 Jan;25(1):65-71. doi: 10.1007/s00330-014-3384-6. Epub 2014 Sep 3.

PMID:
25182625
26.

Contribution of CT quantified emphysema, air trapping and airway wall thickness on pulmonary function in male smokers with and without COPD.

Mohamed Hoesein FA, de Jong PA, Lammers JW, Mali WP, Mets OM, Schmidt M, de Koning HJ, Aalst Cv, Oudkerk M, Vliegenthart R, Ginneken Bv, van Rikxoort EM, Zanen P.

COPD. 2014 Sep;11(5):503-9. doi: 10.3109/15412555.2014.933952. Epub 2014 Aug 5.

PMID:
25093696
27.

Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis.

Smolonska J, Koppelman GH, Wijmenga C, Vonk JM, Zanen P, Bruinenberg M, Curjuric I, Imboden M, Thun GA, Franke L, Probst-Hensch NM, Nürnberg P, Riemersma RA, van Schayck CP, Loth DW, Brusselle GG, Stricker BH, Hofman A, Uitterlinden AG, Lahousse L, London SJ, Loehr LR, Manichaikul A, Barr RG, Donohue KM, Rich SS, Pare P, Bossé Y, Hao K, van den Berge M, Groen HJ, Lammers JW, Mali W, Boezen HM, Postma DS.

Eur Respir J. 2014 Oct;44(4):860-72. doi: 10.1183/09031936.00001914. Epub 2014 Jul 3.

28.

Susceptibility to chronic mucus hypersecretion, a genome wide association study.

Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat M, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort study.

PLoS One. 2014 Apr 8;9(4):e91621. doi: 10.1371/journal.pone.0091621. eCollection 2014. Erratum in: PLoS One. 2015;10(5):e0129524. Obeidat, M A [corrected to Obeidat, Ma'en].

29.

Response to pneumococcal vaccination in mannose-binding lectin-deficient adults with recurrent respiratory tract infections.

van Kessel DA, Hoffman TW, van Velzen-Blad H, Zanen P, Rijkers GT, Grutters JC.

Clin Exp Immunol. 2014 Jul;177(1):272-9. doi: 10.1111/cei.12299.

30.

Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.

Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JH, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, Groen HJ, Postma DS, Wanner A, Rouhani FN, Brantly ML, Powell R, Smith BM, Rabinowitz D, Raffel LJ, Hinckley Stukovsky KD, Crapo JD, Beaty TH, Hokanson JE, Silverman EK, Dupuis J, O'Connor GT, Boezen HM, Rich SS, Barr RG.

Am J Respir Crit Care Med. 2014 Feb 15;189(4):408-18. doi: 10.1164/rccm.201306-1061OC.

31.

Predicting an accelerated lung function decline in smokers: is there a proper threshold?

Mohamed Hoesein FA, Zanen P.

Eur Respir J. 2014 Jan;43(1):307-8. doi: 10.1183/09031936.00086713. No abstract available.

32.

Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD.

Mohamed Hoesein FA, Schmidt M, Mets OM, Gietema HA, Lammers JW, Zanen P, de Koning HJ, van der Aalst C, Oudkerk M, Vliegenthart R, Isgum I, Prokop M, van Ginneken B, van Rikxoort EM, de Jong PA.

Respir Med. 2014 Jan;108(1):136-43. doi: 10.1016/j.rmed.2013.08.014. Epub 2013 Aug 30.

33.

YKL-40 and matrix metalloproteinases as potential biomarkers of inflammation and fibrosis in the development of bronchiolitis obliterans syndrome.

Kastelijn EA, van Moorsel CH, Ruven HJ, Korthagen NM, Kwakkel-van Erp JM, van de Graaf EA, Zanen P, van Kessel DA, Grutters JC.

Sarcoidosis Vasc Diffuse Lung Dis. 2013 Mar;30(1):28-35.

PMID:
24003532
34.

Computed tomography structural lung changes in discordant airflow limitation.

Mohamed Hoesein FA, de Jong PA, Lammers JW, Mali WP, Schmidt M, de Koning HJ, van der Aalst C, Oudkerk M, Vliegenthart R, van Ginneken B, van Rikxoort EM, Zanen P.

PLoS One. 2013 Jun 13;8(6):e65177. doi: 10.1371/journal.pone.0065177. Print 2013.

35.

Lung cancer screening CT-based prediction of cardiovascular events.

Mets OM, Vliegenthart R, Gondrie MJ, Viergever MA, Oudkerk M, de Koning HJ, Mali WP, Prokop M, van Klaveren RJ, van der Graaf Y, Buckens CF, Zanen P, Lammers JW, Groen HJ, Isgum I, de Jong PA.

JACC Cardiovasc Imaging. 2013 Aug;6(8):899-907. doi: 10.1016/j.jcmg.2013.02.008. Epub 2013 Jun 13.

36.

Diagnosis of chronic obstructive pulmonary disease in lung cancer screening Computed Tomography scans: independent contribution of emphysema, air trapping and bronchial wall thickening.

Mets OM, Schmidt M, Buckens CF, Gondrie MJ, Isgum I, Oudkerk M, Vliegenthart R, de Koning HJ, van der Aalst CM, Prokop M, Lammers JW, Zanen P, Mohamed Hoesein FA, Mali WP, van Ginneken B, van Rikxoort EM, de Jong PA.

Respir Res. 2013 May 27;14:59. doi: 10.1186/1465-9921-14-59.

37.

Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study.

Mohamed Hoesein FA, Zanen P, de Jong PA, van Ginneken B, Boezen HM, Groen HJ, Oudkerk M, de Koning HJ, Postma DS, Lammers JW.

Respir Res. 2013 May 20;14:55. doi: 10.1186/1465-9921-14-55.

38.

CT air trapping is independently associated with lung function reduction over time.

Mets OM, de Jong PA, van Ginneken B, Kruitwagen CL, Prokop M, Oudkerk M, Lammers JW, Zanen P.

PLoS One. 2013 Apr 16;8(4):e61783. doi: 10.1371/journal.pone.0061783. Print 2013.

39.

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.

van Setten J, Isgum I, Smolonska J, Ripke S, de Jong PA, Oudkerk M, de Koning H, Lammers JW, Zanen P, Groen HJ, Boezen HM, Postma DS, Wijmenga C, Viergever MA, Mali WP, de Bakker PI.

Atherosclerosis. 2013 Jun;228(2):400-5. doi: 10.1016/j.atherosclerosis.2013.02.039. Epub 2013 Mar 13.

40.

Methotrexate vs azathioprine in second-line therapy of sarcoidosis.

Vorselaars ADM, Wuyts WA, Vorselaars VMM, Zanen P, Deneer VHM, Veltkamp M, Thomeer M, van Moorsel CHM, Grutters JC.

Chest. 2013 Sep;144(3):805-812. doi: 10.1378/chest.12-1728.

PMID:
23538719
41.

Subphenotypes of mild-to-moderate COPD by factor and cluster analysis of pulmonary function, CT imaging and breathomics in a population-based survey.

Fens N, van Rossum AG, Zanen P, van Ginneken B, van Klaveren RJ, Zwinderman AH, Sterk PJ.

COPD. 2013 Jun;10(3):277-85. doi: 10.3109/15412555.2012.744388. Epub 2013 Mar 28.

PMID:
23536961
42.

Randomized controlled observer-blinded treatment of chronic foot eczema with iontophoresis and bath-PUVA.

Tupker RA, Coenraads PJ, Zanen P, Schuttelaar ML.

Acta Derm Venereol. 2013 Jul 6;93(4):456-60. doi: 10.2340/00015555-1537.

43.

Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study.

Dijkstra AE, Postma DS, ten Hacken N, Vonk JM, Oudkerk M, van Ooijen PM, Zanen P, Mohamed Hoesein FA, van Ginneken B, Schmidt M, Groen HJ.

Respir Res. 2013 Jan 28;14:11. doi: 10.1186/1465-9921-14-11.

44.

Variants in the 15q24/25 locus associate with lung function decline in active smokers.

Mohamed Hoesein FA, Wauters E, Janssens W, Groen HJ, Smolonska J, Wijmenga C, Postma DS, Boezen HM, De Jong PA, Decramer M, Lammers JW, Lambrechts D, Zanen P.

PLoS One. 2013;8(1):e53219. doi: 10.1371/journal.pone.0053219. Epub 2013 Jan 18.

45.

Response.

Mohamed Hoesein FAA, Zanen P.

Chest. 2013 Jan;143(1):277. doi: 10.1378/chest.12-2192. No abstract available.

PMID:
23276867
46.

Early identification of small airways disease on lung cancer screening CT: comparison of current air trapping measures.

Mets OM, Zanen P, Lammers JW, Isgum I, Gietema HA, van Ginneken B, Prokop M, de Jong PA.

Lung. 2012 Dec;190(6):629-33. doi: 10.1007/s00408-012-9422-8. Epub 2012 Oct 12.

PMID:
23064488
47.

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

Hansel NN, Ruczinski I, Rafaels N, Sin DD, Daley D, Malinina A, Huang L, Sandford A, Murray T, Kim Y, Vergara C, Heckbert SR, Psaty BM, Li G, Elliott WM, Aminuddin F, Dupuis J, O'Connor GT, Doheny K, Scott AF, Boezen HM, Postma DS, Smolonska J, Zanen P, Mohamed Hoesein FA, de Koning HJ, Crystal RG, Tanaka T, Ferrucci L, Silverman E, Wan E, Vestbo J, Lomas DA, Connett J, Wise RA, Neptune ER, Mathias RA, Paré PD, Beaty TH, Barnes KC.

Hum Genet. 2013 Jan;132(1):79-90. doi: 10.1007/s00439-012-1219-6. Epub 2012 Sep 18.

48.

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Soler Artigas M, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD, Stricker BH.

Am J Respir Crit Care Med. 2012 Oct 1;186(7):622-32. doi: 10.1164/rccm.201202-0366OC. Epub 2012 Jul 26.

49.

Lung function decline in male heavy smokers relates to baseline airflow obstruction severity.

Mohamed Hoesein FAA, Zanen P, Boezen HM, Groen HJM, van Ginneken B, de Jong PA, Postma DS, Lammers JJ.

Chest. 2012 Dec;142(6):1530-1538. doi: 10.1378/chest.11-2837.

PMID:
22722231
50.

Variation in quantitative CT air trapping in heavy smokers on repeat CT examinations.

Mets OM, Isgum I, Mol CP, Gietema HA, Zanen P, Prokop M, de Jong PA.

Eur Radiol. 2012 Dec;22(12):2710-7. doi: 10.1007/s00330-012-2526-y. Epub 2012 Jun 14.

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