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Items: 13

1.

Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition.

Lee CM, Zane NR, Veal G, Thakker DR.

CPT Pharmacometrics Syst Pharmacol. 2019 Aug 16. doi: 10.1002/psp4.12453. [Epub ahead of print]

2.

Mechanisms of antimicrobial-induced nephrotoxicity in children.

Downes KJ, Hayes M, Fitzgerald JC, Pais GM, Liu J, Zane NR, Goldstein SL, Scheetz MH, Zuppa AF.

J Antimicrob Chemother. 2019 Aug 1. pii: dkz325. doi: 10.1093/jac/dkz325. [Epub ahead of print]

PMID:
31369087
3.

Morphine Dose Optimization in Critically Ill Pediatric Patients With Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study.

Zuppa AF, Benitez GR, Zane NR, Curley MAQ, Bradfield J, Hakonarson H, Gastonguay MS, Moorthy G, Prodell J, Gastonguay MR.

Crit Care Med. 2019 Jun;47(6):e485-e494. doi: 10.1097/CCM.0000000000003741.

PMID:
30920410
4.

Vancomycin Prescribing and Therapeutic Drug Monitoring in Children With and Without Acute Kidney Injury After Cardiac Arrest.

Fitzgerald JC, Zane NR, Himebauch AS, Reedy MD, Downes KJ, Topjian AA, Furth SL, Thomas NJ, Scheetz MH, Zuppa AF.

Paediatr Drugs. 2019 Apr;21(2):107-112. doi: 10.1007/s40272-019-00328-8.

PMID:
30864056
5.

Midazolam Dose Optimization in Critically Ill Pediatric Patients With Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study.

Zuppa AF, Conrado DJ, Zane NR, Curley MAQ, Bradfield J, Hakonarson H, Gastonguay MS, Moorthy G, Prodell J, Gastonguay MR.

Crit Care Med. 2019 Apr;47(4):e301-e309. doi: 10.1097/CCM.0000000000003638.

PMID:
30672747
6.

A Population Pharmacokinetic Analysis to Study the Effect of Extracorporeal Membrane Oxygenation on Cefepime Disposition in Children.

Zuppa AF, Zane NR, Moorthy G, Dalton HJ, Abraham A, Reeder RW, Carcillo JA, Yates AR, Meert KL, Berg RA, Sapru A, Mourani P, Notterman DA, Dean JM, Gastonguay MR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2019 Jan;20(1):62-70. doi: 10.1097/PCC.0000000000001786.

PMID:
30431557
7.

Use of Intravenous Acetaminophen in Children for Analgesia After Spinal Fusion Surgery: A Randomized Clinical Trial.

Rizkalla N, Zane NR, Prodell JL, Elci OU, Maxwell LG, DiLiberto MA, Zuppa AF.

J Pediatr Pharmacol Ther. 2018 Sep-Oct;23(5):395-404. doi: 10.5863/1551-6776-23.5.395.

8.

Cytochrome P450 and flavin-containing monooxygenase families: age-dependent differences in expression and functional activity.

Zane NR, Chen Y, Wang MZ, Thakker DR.

Pediatr Res. 2018 Feb;83(2):527-535. doi: 10.1038/pr.2017.226. Epub 2017 Nov 1.

PMID:
28922349
9.

A Population Pharmacokinetic Analysis to Study the Effect of Therapeutic Hypothermia on Vancomycin Disposition in Children Resuscitated From Cardiac Arrest.

Zane NR, Reedy MD, Gastonguay MR, Himebauch AS, Ramsey EZ, Topjian AA, Zuppa AF.

Pediatr Crit Care Med. 2017 Jul;18(7):e290-e297. doi: 10.1097/PCC.0000000000001198.

10.

An opportunistic study evaluating pharmacokinetics of sildenafil for the treatment of pulmonary hypertension in infants.

Thakkar N, Gonzalez D, Cohen-Wolkowiez M, Massaro MM, Bernhardt J, Zane NR, Laughon MM.

J Perinatol. 2016 Sep;36(9):744-7. doi: 10.1038/jp.2016.79. Epub 2016 May 12.

11.
12.

Response to: "Prediction of Voriconazole Non-Linear Pharmacokinetics Using a Paediatric Physiologically Based Pharmacokinetic Modelling Approach".

Zane NR, Thakker DR.

Clin Pharmacokinet. 2015 May;54(5):569-72. doi: 10.1007/s40262-015-0254-6. No abstract available.

PMID:
25735635
13.

A physiologically based pharmacokinetic model for voriconazole disposition predicts intestinal first-pass metabolism in children.

Zane NR, Thakker DR.

Clin Pharmacokinet. 2014 Dec;53(12):1171-82. doi: 10.1007/s40262-014-0181-y.

PMID:
25245942

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