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Dickkopf-2 (DKK2) as Context Dependent Factor in Patients with Esophageal Adenocarcinoma.

Schiffmann LM, Loeser H, Jacob AS, Maus M, Fuchs H, Zhao Y, Tharun L, Essakly A, Iannos Damanakis A, Zander T, Büttner R, Schröder W, Bruns C, Quaas A, Gebauer F.

Cancers (Basel). 2020 Feb 14;12(2). pii: E451. doi: 10.3390/cancers12020451.


Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma.

Wagener-Ryczek S, Schoemmel M, Kraemer M, Bruns C, Schroeder W, Zander T, Gebauer F, Alakus H, Merkelbach-Bruse S, Buettner R, Loeser H, Thelen M, Schlößer HA, Quaas A.

Cancer Immunol Immunother. 2020 Jan 20. doi: 10.1007/s00262-019-02475-w. [Epub ahead of print]


Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.

Schallenberg S, Bork J, Essakly A, Alakus H, Buettner R, Hillmer AM, Bruns C, Schroeder W, Zander T, Loeser H, Gebauer F, Quaas A.

BMC Cancer. 2020 Jan 6;20(1):12. doi: 10.1186/s12885-019-6425-3.


PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis.

Essakly A, Loeser H, Kraemer M, Alakus H, Chon SH, Zander T, Buettner R, Hillmer AM, Bruns CJ, Schroeder W, Gebauer F, Quaas A.

Transl Oncol. 2020 Feb;13(2):157-164. doi: 10.1016/j.tranon.2019.10.013. Epub 2019 Dec 19.


Which is the best-suited landmark to assess the thoracic orientation?

Zander T, Pan F, Schmidt H.

J Biomech. 2019 Nov 26:109545. doi: 10.1016/j.jbiomech.2019.109545. [Epub ahead of print]


Cognitive and affective probing: a tutorial and review of active learning for neuroadaptive technology.

Krol LR, Haselager P, Zander TO.

J Neural Eng. 2020 Jan 31;17(1):012001. doi: 10.1088/1741-2552/ab5bb5.


Sex-dependent differences in lumbo-pelvic coordination for different lifting tasks: A study on asymptomatic adults.

Pan F, Firouzabadi A, Zander T, Schmidt H.

J Biomech. 2019 Nov 12:109505. doi: 10.1016/j.jbiomech.2019.109505. [Epub ahead of print]


A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer.

Bendell JC, Bischoff HG, Hwang J, Reinhardt HC, Zander T, Wang X, Hynes S, Pitou C, Campbell R, Iversen P, Farrington DL, Bell-McGuinn K, Thomas M.

Invest New Drugs. 2019 Nov 9. doi: 10.1007/s10637-019-00873-6. [Epub ahead of print]


Prehospital needle thoracostomy: What are the indications and is a post-trauma center arrival chest tube required?

Axtman BC, Stewart KE, Robbins JM, Garwe T, Sarwar Z, Gonzalez RA, Zander TL, Balla FM, Albrecht RM.

Am J Surg. 2019 Dec;218(6):1138-1142. doi: 10.1016/j.amjsurg.2019.09.020. Epub 2019 Sep 21.


How reproducible do we stand and sit? Indications for a reliable sagittal spinal assessment.

Pan F, Zander T, Reitmaier S, Bashkuev M, Schmidt H.

Clin Biomech (Bristol, Avon). 2019 Dec;70:123-130. doi: 10.1016/j.clinbiomech.2019.08.011. Epub 2019 Aug 23.


Influence of high hydrostatic pressure on solid supported DPPC bilayers with hyaluronan in the presence of Ca2+ ions.

Zander T, Wieland DCF, Raj A, Salmen P, Dogan S, Dėdinaitė A, Garamus VM, Schreyer A, Claesson PM, Willumeit-Römer R.

Soft Matter. 2019 Sep 18;15(36):7295-7304. doi: 10.1039/c9sm01066a.


The economic burden of endoscopic treatment for anastomotic leaks following oncological Ivor Lewis esophagectomy.

Baltin C, Kron F, Urbanski A, Zander T, Kron A, Berlth F, Kleinert R, Hallek M, Hoelscher AH, Chon SH.

PLoS One. 2019 Aug 28;14(8):e0221406. doi: 10.1371/journal.pone.0221406. eCollection 2019.


Removal of retrievable inferior vena cava filters before discharge: Is it associated with increased incidence of pulmonary embolism?

Robbins JM, Garwe T, McCarthy CK, Sarwar Z, Gonzalez RA, Zander TL, Jalla AN, Conner KS, Stewart KE, Albrecht RM.

J Trauma Acute Care Surg. 2019 Nov;87(5):1113-1118. doi: 10.1097/TA.0000000000002395.


Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma.

Schiffmann LM, Göbel H, Löser H, Schorn F, Werthenbach JP, Fuchs HF, Plum PS, Bludau M, Zander T, Schröder W, Bruns CJ, Kashkar H, Quaas A, Gebauer F.

BMC Cancer. 2019 May 31;19(1):531. doi: 10.1186/s12885-019-5722-1.


Short regimen of rituximab plus lenalidomide in follicular lymphoma patients in need of first-line therapy.

Zucca E, Rondeau S, Vanazzi A, Østenstad B, Mey UJM, Rauch D, Wahlin BE, Hitz F, Hernberg M, Johansson AS, de Nully Brown P, Hagberg H, Ferreri AJM, Lohri A, Novak U, Zander T, Bersvendsen H, Bargetzi M, Mingrone W, Krasniqi F, Dirnhofer S, Hayoz S, Hawle H, Vilei SB, Ghielmini M, Kimby E; Swiss Group for Clinical Cancer Research and the Nordic Lymphoma Group.

Blood. 2019 Jul 25;134(4):353-362. doi: 10.1182/blood-2018-10-879643. Epub 2019 May 17.


The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma.

Loeser H, Kraemer M, Gebauer F, Bruns C, Schröder W, Zander T, Persa OD, Alakus H, Hoelscher A, Buettner R, Lohneis P, Quaas A.

Oncoimmunology. 2019 Feb 27;8(5):e1581546. doi: 10.1080/2162402X.2019.1581546. eCollection 2019.


Updated recommendations for diagnosis and treatment of plasma cell myeloma in Switzerland.

Samaras P, Bargetzi M, Betticher DC, Driessen C, Duchosal MA, Heim D, Ketterer N, Lerch E, Matthes T, Mey U, Pabst T, Schmidt A, Taverna C, Zander T, Renner C.

Swiss Med Wkly. 2019 Apr 3;149:w20031. doi: 10.4414/smw.2019.20031. eCollection 2019 Mar 25.


High incidence of reversible renal toxicity of dose-intensified bendamustine-based high-dose chemotherapy in lymphoma and myeloma patients.

Prediletto I, Farag SA, Bacher U, Jeker B, Mansouri Taleghani B, Brégy R, Zander T, Betticher D, Egger T, Novak U, Pabst T.

Bone Marrow Transplant. 2019 Dec;54(12):1923-1925. doi: 10.1038/s41409-019-0508-2. Epub 2019 Mar 19. No abstract available.


Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma.

Quaas A, Heydt C, Waldschmidt D, Alakus H, Zander T, Goeser T, Kasper P, Bruns C, Brunn A, Roth W, Hartmann N, Bunck A, Schmidt M, Buettner R, Merkelbach-Bruse S.

BMC Gastroenterol. 2019 Feb 4;19(1):21. doi: 10.1186/s12876-019-0942-z.


HER2/neu (ERBB2) expression and gene amplification correlates with better survival in esophageal adenocarcinoma.

Plum PS, Gebauer F, Krämer M, Alakus H, Berlth F, Chon SH, Schiffmann L, Zander T, Büttner R, Hölscher AH, Bruns CJ, Quaas A, Loeser H.

BMC Cancer. 2019 Jan 8;19(1):38. doi: 10.1186/s12885-018-5242-4.


Prolonged survival with increasing duration of lenalidomide maintenance after autologous transplant for multiple myeloma.

Amsler IG, Jeker B, Mansouri Taleghani B, Bacher U, Betticher D, Egger T, Zander T, Luethi JM, Novak U, Pabst T.

Leuk Lymphoma. 2019 Feb;60(2):511-514. doi: 10.1080/10428194.2018.1473577. Epub 2019 Jan 8. No abstract available.


The paralyzing effect of insurance status on throughput of acute spinal cord patients.

Lindemuth M, Garwe T, Venincasa K, Zander T, McCarthy C, Bonds M, Sarwar Z, Albrecht R, Lees J, Scifres A, Cross A.

Am J Surg. 2019 Jun;217(6):1060-1064. doi: 10.1016/j.amjsurg.2018.10.049. Epub 2018 Nov 14.


B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies.

Schlößer HA, Thelen M, Lechner A, Wennhold K, Garcia-Marquez MA, Rothschild SI, Staib E, Zander T, Beutner D, Gathof B, Gilles R, Cukuroglu E, Göke J, Shimabukuro-Vornhagen A, Drebber U, Quaas A, Bruns CJ, Hölscher AH, Von Bergwelt-Baildon MS.

Oncoimmunology. 2018 Nov 2;8(1):e1512458. doi: 10.1080/2162402X.2018.1512458. eCollection 2019.


Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.

Schiffmann LM, Fritsch M, Gebauer F, Günther SD, Stair NR, Seeger JM, Thangarajah F, Dieplinger G, Bludau M, Alakus H, Göbel H, Quaas A, Zander T, Hilberg F, Bruns CJ, Kashkar H, Coutelle O.

Br J Cancer. 2019 Jan;120(1):69-78. doi: 10.1038/s41416-018-0198-3. Epub 2018 Oct 31.


Genomic Characterization of TP53-Wild-Type Esophageal Carcinoma.

Quaas A, Heydt C, Gebauer F, Alakus H, Loeser H, Buettner R, Hillmer A, Bruns C, Merkelbach-Bruse S, Zander T, Frommolt P.

Transl Oncol. 2019 Jan;12(1):154-161. doi: 10.1016/j.tranon.2018.09.007. Epub 2018 Oct 11. No abstract available.


Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence.

Pasternack H, Fassunke J, Plum PS, Chon SH, Hescheler DA, Gassa A, Merkelbach-Bruse S, Bruns CJ, Perner S, Hallek M, Büttner R, Bollschweiler E, Hölscher AH, Quaas A, Zander T, Weiss J, Alakus H.

Sci Rep. 2018 Oct 8;8(1):14941. doi: 10.1038/s41598-018-33027-4.


Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma.

Schmitt A, Feldmann G, Zander T, Reinhardt HC.

Oncol Res Treat. 2018;41(10):619-625. doi: 10.1159/000493401. Epub 2018 Sep 28. Review.


Promising activity of nelfinavir-bortezomib-dexamethasone in proteasome inhibitor-refractory multiple myeloma.

Driessen C, Müller R, Novak U, Cantoni N, Betticher D, Mach N, Rüfer A, Mey U, Samaras P, Ribi K, Besse L, Besse A, Berset C, Rondeau S, Hawle H, Hitz F, Pabst T, Zander T.

Blood. 2018 Nov 8;132(19):2097-2100. doi: 10.1182/blood-2018-05-851170. Epub 2018 Sep 20. No abstract available.


Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer.

Kron A, Alidousty C, Scheffler M, Merkelbach-Bruse S, Seidel D, Riedel R, Ihle MA, Michels S, Nogova L, Fassunke J, Heydt C, Kron F, Ueckeroth F, Serke M, Krüger S, Grohe C, Koschel D, Benedikter J, Kaminsky B, Schaaf B, Braess J, Sebastian M, Kambartel KO, Thomas R, Zander T, Schultheis AM, Büttner R, Wolf J.

Ann Oncol. 2018 Oct 1;29(10):2068-2075. doi: 10.1093/annonc/mdy333.


SEREEGA: Simulating event-related EEG activity.

Krol LR, Pawlitzki J, Lotte F, Gramann K, Zander TO.

J Neurosci Methods. 2018 Nov 1;309:13-24. doi: 10.1016/j.jneumeth.2018.08.001. Epub 2018 Aug 14.


The shape and mobility of the thoracic spine in asymptomatic adults - A systematic review of in vivo studies.

Pan F, Firouzabadi A, Reitmaier S, Zander T, Schmidt H.

J Biomech. 2018 Sep 10;78:21-35. doi: 10.1016/j.jbiomech.2018.07.041. Epub 2018 Aug 4.


Diagnosis and treatment of follicular lymphoma: an update.

Bargetzi M, Baumann R, Cogliatti S, Dietrich PY, Duchosal M, Goede J, Hitz F, Konermann C, Lohri A, Mey U, Novak U, Papachristofilou A, Stenner F, Taverna C, Zander T, Renner C.

Swiss Med Wkly. 2018 Jul 24;148:w14635. doi: 10.4414/smw.2018.14635. eCollection 2018. Review.


Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus.

Plum PS, Ulase D, Bollschweiler E, Chon SH, Berlth F, Zander T, Alakus H, Hölscher AH, Bruns CJ, Schallenberg S, Quaas A, Loeser H.

J Cancer Res Clin Oncol. 2018 Sep;144(9):1731-1739. doi: 10.1007/s00432-018-2698-1. Epub 2018 Jul 4.


Therapy susceptible germline-related BRCA 1-mutation in a case of metastasized mixed adeno-neuroendocrine carcinoma (MANEC) of the small bowel.

Quaas A, Waldschmidt D, Alakus H, Zander T, Heydt C, Goeser T, Daheim M, Kasper P, Plum P, Bruns C, Brunn A, Roth W, Hartmann N, Bunck A, Schmidt M, Göbel H, Tharun L, Buettner R, Merkelbach-Bruse S.

BMC Gastroenterol. 2018 May 31;18(1):75. doi: 10.1186/s12876-018-0803-1.


Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries.

Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ.

J Trauma Acute Care Surg. 2018 Nov;85(5):858-866. doi: 10.1097/TA.0000000000001989.


The effect of age and sex on the cervical range of motion - A systematic review and meta-analysis.

Pan F, Arshad R, Zander T, Reitmaier S, Schroll A, Schmidt H.

J Biomech. 2018 Jun 25;75:13-27. doi: 10.1016/j.jbiomech.2018.04.047. Epub 2018 May 7.


Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

George J, Walter V, Peifer M, Alexandrov LB, Seidel D, Leenders F, Maas L, Müller C, Dahmen I, Delhomme TM, Ardin M, Leblay N, Byrnes G, Sun R, De Reynies A, McLeer-Florin A, Bosco G, Malchers F, Menon R, Altmüller J, Becker C, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soloway MG, Wilkerson MD, Cun Y, McKay JD, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Lemaitre N, Soltermann A, Weder W, Tischler V, Brustugun OT, Lund-Iversen M, Helland Å, Solberg S, Ansén S, Wright G, Solomon B, Roz L, Pastorino U, Petersen I, Clement JH, Sänger J, Wolf J, Vingron M, Zander T, Perner S, Travis WD, Haas SA, Olivier M, Foll M, Büttner R, Hayes DN, Brambilla E, Fernandez-Cuesta L, Thomas RK.

Nat Commun. 2018 Mar 13;9(1):1048. doi: 10.1038/s41467-018-03099-x.


[Profit center analysis of esophagectomy : Economical analysis of transthoracic esophagectomy depending on postoperative complications].

Baltin CT, Bludau M, Kron F, Zander T, Hallek M, Hölscher AH, Schröder W.

Chirurg. 2018 Mar;89(3):229-236. doi: 10.1007/s00104-018-0590-9. German.


High protein and mRNA expression levels of TUBB3 (class III ß-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas.

Loeser H, Schallenberg S, von Winterfeld M, Tharun L, Alakus H, Hölscher A, Bollschweiler E, Buettner R, Zander T, Quaas A.

Oncotarget. 2017 Dec 11;8(70):115179-115189. doi: 10.18632/oncotarget.23112. eCollection 2017 Dec 29.


Prolonged survival after second autologous transplantation and lenalidomide maintenance for salvage treatment of myeloma patients at first relapse after prior autograft.

Gössi U, Jeker B, Mansouri Taleghani B, Bacher U, Novak U, Betticher D, Egger T, Zander T, Pabst T.

Hematol Oncol. 2018 Apr;36(2):436-444. doi: 10.1002/hon.2490. Epub 2018 Jan 24.


CabaGast: multicentre, Phase II study with cabazitaxel in previously treated patients with advanced or metastatic adenocarcinoma of the esophagogastric junction and stomach.

Schmalenberg H, Al-Batran SE, Pauligk C, Zander T, Reichart A, Lindig U, Kleiß M, Müller L, Bolling C, Seufferlein T, Reichardt P, Kullmann F, Eschenburg H, Schmittel A, Egger M, Block A, Goetze TO.

J Cancer Res Clin Oncol. 2018 Mar;144(3):559-569. doi: 10.1007/s00432-017-2565-5. Epub 2017 Dec 28.


The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI.

Al-Batran SE, Goetze TO, Mueller DW, Vogel A, Winkler M, Lorenzen S, Novotny A, Pauligk C, Homann N, Jungbluth T, Reissfelder C, Caca K, Retter S, Horndasch E, Gumpp J, Bolling C, Fuchs KH, Blau W, Padberg W, Pohl M, Wunsch A, Michl P, Mannes F, Schwarzbach M, Schmalenberg H, Hohaus M, Scholz C, Benckert C, Knorrenschild JR, Kanngießer V, Zander T, Alakus H, Hofheinz RD, Roedel C, Shah MA, Sasako M, Lorenz D, Izbicki J, Bechstein WO, Lang H, Moenig SP.

BMC Cancer. 2017 Dec 28;17(1):893. doi: 10.1186/s12885-017-3918-9.


Workshops of the Sixth International Brain-Computer Interface Meeting: brain-computer interfaces past, present, and future.

Huggins JE, Guger C, Ziat M, Zander TO, Taylor D, Tangermann M, Soria-Frisch A, Simeral J, Scherer R, Rupp R, Ruffini G, Robinson DKR, Ramsey NF, Nijholt A, Müller-Putz G, McFarland DJ, Mattia D, Lance BJ, Kindermans PJ, Iturrate I, Herff C, Gupta D, Do AH, Collinger JL, Chavarriaga R, Chase SM, Bleichner MG, Batista A, Anderson CW, Aarnoutse EJ.

Brain Comput Interfaces (Abingdon). 2017;4(1-2):3-36. doi: 10.1080/2326263X.2016.1275488. Epub 2017 Jan 30.


Sleep increases explicit solutions and reduces intuitive judgments of semantic coherence.

Zander T, Volz KG, Born J, Diekelmann S.

Learn Mem. 2017 Nov 15;24(12):641-645. doi: 10.1101/lm.044511.116. Print 2017 Dec.


Are there characteristic motion patterns in the lumbar spine during flexion?

Zander T, Bashkuev M, Schmidt H.

J Biomech. 2018 Mar 21;70:77-81. doi: 10.1016/j.jbiomech.2017.09.006. Epub 2017 Sep 14.


Spinal loads and trunk muscles forces during level walking - A combined in vivo and in silico study on six subjects.

Arshad R, Angelini L, Zander T, Di Puccio F, El-Rich M, Schmidt H.

J Biomech. 2018 Mar 21;70:113-123. doi: 10.1016/j.jbiomech.2017.08.020. Epub 2017 Aug 26.


Effect of arm swinging on lumbar spine and hip joint forces.

Angelini L, Damm P, Zander T, Arshad R, Di Puccio F, Schmidt H.

J Biomech. 2018 Mar 21;70:185-195. doi: 10.1016/j.jbiomech.2017.09.011. Epub 2017 Sep 14.


Somatic BRCA1-associated protein 1 (BAP1) loss is an early and rare event in esophageal adenocarcinoma.

Loeser H, Waldschmidt D, Kuetting F, Schallenberg S, Zander T, Bollschweiler E, Hoelscher A, Weckermann K, Plum P, Alakus H, Buettner R, Quaas A.

Mol Clin Oncol. 2017 Aug;7(2):225-228. doi: 10.3892/mco.2017.1286. Epub 2017 Jun 8.


Affective Aspects of Perceived Loss of Control and Potential Implications for Brain-Computer Interfaces.

Grissmann S, Zander TO, Faller J, Brönstrup J, Kelava A, Gramann K, Gerjets P.

Front Hum Neurosci. 2017 Jul 19;11:370. doi: 10.3389/fnhum.2017.00370. eCollection 2017.


Scrutinizing the Emotional Nature of Intuitive Coherence Judgments.

Zander T, Fernandez Cruz AL, Winkelmann MP, Volz KG.

J Behav Decis Mak. 2017 Jul;30(3):693-707. doi: 10.1002/bdm.1982. Epub 2016 Sep 23.

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