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Items: 1 to 50 of 97

1.

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate.

Sica V, Bravo-San Pedro JM, Izzo V, Pol J, Pierredon S, Enot D, Durand S, Bossut N, Chery A, Souquere S, Pierron G, Vartholomaiou E, Zamzami N, Soussi T, Sauvat A, Mondragón L, Kepp O, Galluzzi L, Martinou JC, Hess-Stumpp H, Ziegelbauer K, Kroemer G, Maiuri MC.

Cell Rep. 2019 Apr 16;27(3):820-834.e9. doi: 10.1016/j.celrep.2019.03.058.

2.

Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux.

Zhang S, Wang Y, Xie W, Howe ENW, Busschaert N, Sauvat A, Leduc M, Gomes-da-Silva LC, Chen G, Martins I, Deng X, Maiuri L, Kepp O, Soussi T, Gale PA, Zamzami N, Kroemer G.

Cell Death Dis. 2019 Apr 3;10(4):301. doi: 10.1038/s41419-019-1536-y.

3.

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux.

Zhang S, Wang Y, Xie W, Howe ENW, Busschaert N, Sauvat A, Leduc M, Gomes-da-Silva LC, Chen G, Martins I, Deng X, Maiuri L, Kepp O, Soussi T, Gale PA, Zamzami N, Kroemer G.

Cell Death Dis. 2019 Mar 11;10(3):242. doi: 10.1038/s41419-019-1474-8. Erratum in: Cell Death Dis. 2019 Apr 3;10(4):301.

4.

Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.

Zhang S, Stoll G, Pedro JMBS, Sica V, Sauvat A, Obrist F, Kepp O, Li Y, Maiuri L, Zamzami N, Kroemer G.

Cell Death Dis. 2018 Feb 7;9(2):191. doi: 10.1038/s41419-017-0235-9.

5.

Regulation of autophagy by cytosolic acetyl-coenzyme A.

Mariño G, Pietrocola F, Eisenberg T, Kong Y, Malik SA, Andryushkova A, Schroeder S, Pendl T, Harger A, Niso-Santano M, Zamzami N, Scoazec M, Durand S, Enot DP, Fernández ÁF, Martins I, Kepp O, Senovilla L, Bauvy C, Morselli E, Vacchelli E, Bennetzen M, Magnes C, Sinner F, Pieber T, López-Otín C, Maiuri MC, Codogno P, Andersen JS, Hill JA, Madeo F, Kroemer G.

Mol Cell. 2014 Mar 6;53(5):710-25. doi: 10.1016/j.molcel.2014.01.016. Epub 2014 Feb 20.

6.

Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins.

Pietrocola F, Mariño G, Lissa D, Vacchelli E, Malik SA, Niso-Santano M, Zamzami N, Galluzzi L, Maiuri MC, Kroemer G.

Cell Cycle. 2012 Oct 15;11(20):3851-60. doi: 10.4161/cc.22027.

7.

Diffuse peritoneal lymphomatosis simulating peritoneal carcinomatosis.

Sharifah MI, Zamzami NA, Rafeah TN.

Med J Malaysia. 2011 Aug;66(3):270-2.

8.

Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death.

Tajeddine N, Galluzzi L, Kepp O, Hangen E, Morselli E, Senovilla L, Araujo N, Pinna G, Larochette N, Zamzami N, Modjtahedi N, Harel-Bellan A, Kroemer G.

Oncogene. 2008 Jul 10;27(30):4221-32. doi: 10.1038/onc.2008.63. Epub 2008 Mar 24.

PMID:
18362892
9.

Structure-function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA.

Pauleau AL, Larochette N, Giordanetto F, Scholz SR, Poncet D, Zamzami N, Goldmacher VS, Kroemer G.

Oncogene. 2007 Nov 1;26(50):7067-80. Epub 2007 May 14.

PMID:
17496930
10.

Measurement of membrane permeability and the permeability transition of mitochondria.

Zamzami N, Maisse C, Métivier D, Kroemer G.

Methods Cell Biol. 2007;80:327-40. Review. No abstract available.

PMID:
17445702
11.

Methods for the assessment of mitochondrial membrane permeabilization in apoptosis.

Galluzzi L, Zamzami N, de La Motte Rouge T, Lemaire C, Brenner C, Kroemer G.

Apoptosis. 2007 May;12(5):803-13. Review.

PMID:
17294081
12.

GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.

Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, Larochette N, Zamzami N, Jan G, Kroemer G, Brenner C.

Oncogene. 2007 Apr 19;26(18):2606-20. Epub 2006 Oct 30.

PMID:
17072346
13.

Mitochondria as therapeutic targets for cancer chemotherapy.

Galluzzi L, Larochette N, Zamzami N, Kroemer G.

Oncogene. 2006 Aug 7;25(34):4812-30. Review.

PMID:
16892093
14.

Mitochondrial permeability transition in apoptosis and necrosis.

Zamzami N, Larochette N, Kroemer G.

Cell Death Differ. 2005 Nov;12 Suppl 2:1478-80. No abstract available.

15.

p53 in apoptosis control: an introduction.

Zamzami N, Kroemer G.

Biochem Biophys Res Commun. 2005 Jun 10;331(3):685-7. Review. No abstract available.

PMID:
15865922
16.

Viral proteins targeting mitochondria: controlling cell death.

Boya P, Pauleau AL, Poncet D, Gonzalez-Polo RA, Zamzami N, Kroemer G.

Biochim Biophys Acta. 2004 Dec 6;1659(2-3):178-89. Review.

17.

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria.

Arnoult D, Bartle LM, Skaletskaya A, Poncet D, Zamzami N, Park PU, Sharpe J, Youle RJ, Goldmacher VS.

Proc Natl Acad Sci U S A. 2004 May 25;101(21):7988-93. Epub 2004 May 17.

18.
19.

An anti-apoptotic viral protein that recruits Bax to mitochondria.

Poncet D, Larochette N, Pauleau AL, Boya P, Jalil AA, Cartron PF, Vallette F, Schnebelen C, Bartle LM, Skaletskaya A, Boutolleau D, Martinou JC, Goldmacher VS, Kroemer G, Zamzami N.

J Biol Chem. 2004 May 21;279(21):22605-14. Epub 2004 Mar 5.

20.

Palmitate induces apoptosis via a direct effect on mitochondria.

de Pablo MA, Susin SA, Jacotot E, Larochette N, Costantini P, Ravagnan L, Zamzami N, Kroemer G.

Apoptosis. 1999 Apr;4(2):81-7.

PMID:
14634285
21.

Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization.

Poncet D, Boya P, Métivier D, Zamzami N, Kroemer G.

Apoptosis. 2003 Oct;8(5):521-30.

PMID:
14601558
22.

Mitochondrion-dependent caspase activation by the HIV-1 envelope.

Roumier T, Castedo M, Perfettini JL, Andreau K, Métivier D, Zamzami N, Kroemer G.

Biochem Pharmacol. 2003 Oct 15;66(8):1321-9.

PMID:
14555204
23.
24.

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion.

Boya P, Andreau K, Poncet D, Zamzami N, Perfettini JL, Metivier D, Ojcius DM, Jäättelä M, Kroemer G.

J Exp Med. 2003 May 19;197(10):1323-34.

25.

Mitochondrion-targeted apoptosis regulators of viral origin.

Boya P, Roumier T, Andreau K, Gonzalez-Polo RA, Zamzami N, Castedo M, Kroemer G.

Biochem Biophys Res Commun. 2003 May 9;304(3):575-81. Review.

PMID:
12729592
26.

Possible contribution of apoptosis-inducing factor (AIF) and reactive oxygen species (ROS) to UVB-induced caspase-independent cell death in the T cell line Jurkat.

Murahashi H, Azuma H, Zamzami N, Furuya KJ, Ikebuchi K, Yamaguchi M, Yamada Y, Sato N, Fujihara M, Kroemer G, Ikeda H.

J Leukoc Biol. 2003 Mar;73(3):399-406.

PMID:
12629154
27.

Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?

Zamzami N, Kroemer G.

Curr Biol. 2003 Jan 21;13(2):R71-3.

28.

Quantitation of mitochondrial alterations associated with apoptosis.

Castedo M, Ferri K, Roumier T, Métivier D, Zamzami N, Kroemer G.

J Immunol Methods. 2002 Jul 1;265(1-2):39-47. Review.

PMID:
12072177
29.

Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria.

Candé C, Cohen I, Daugas E, Ravagnan L, Larochette N, Zamzami N, Kroemer G.

Biochimie. 2002 Feb-Mar;84(2-3):215-22. Review.

PMID:
12022952
30.

Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization.

Boya P, Cohen I, Zamzami N, Vieira HL, Kroemer G.

Cell Death Differ. 2002 Apr;9(4):465-7. No abstract available.

31.

Pre-processed caspase-9 contained in mitochondria participates in apoptosis.

Costantini P, Bruey JM, Castedo M, Métivier D, Loeffler M, Susin SA, Ravagnan L, Zamzami N, Garrido C, Kroemer G.

Cell Death Differ. 2002 Jan;9(1):82-8.

32.

Heat-shock protein 70 antagonizes apoptosis-inducing factor.

Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jäättelä M, Penninger JM, Garrido C, Kroemer G.

Nat Cell Biol. 2001 Sep;3(9):839-43.

PMID:
11533664
33.

The mitochondrion in apoptosis: how Pandora's box opens.

Zamzami N, Kroemer G.

Nat Rev Mol Cell Biol. 2001 Jan;2(1):67-71. Review.

PMID:
11413468
34.

Measurement of membrane permeability and permeability transition of mitochondria.

Zamzami N, Maisse C, Métivier D, Kroemer G.

Methods Cell Biol. 2001;65:147-58. No abstract available.

PMID:
11381591
35.

Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.

Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW.

Oncogene. 2001 Apr 12;20(16):1939-52.

36.

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.

Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY, Sasaki T, Elia AJ, Cheng HY, Ravagnan L, Ferri KF, Zamzami N, Wakeham A, Hakem R, Yoshida H, Kong YY, Mak TW, Zúñiga-Pflücker JC, Kroemer G, Penninger JM.

Nature. 2001 Mar 29;410(6828):549-54.

PMID:
11279485
37.

Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor.

Loeffler M, Daugas E, Susin SA, Zamzami N, Metivier D, Nieminen AL, Brothers G, Penninger JM, Kroemer G.

FASEB J. 2001 Mar;15(3):758-67.

PMID:
11259394
38.

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.

Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J, Rustin P, Métivier D, Lenoir C, Geuskens M, Vieira HL, Loeffler M, Belzacq AS, Briand JP, Zamzami N, Edelman L, Xie ZH, Reed JC, Roques BP, Kroemer G.

J Exp Med. 2001 Feb 19;193(4):509-19.

39.

Bid acts on the permeability transition pore complex to induce apoptosis.

Zamzami N, El Hamel C, Maisse C, Brenner C, Muñoz-Pinedo C, Belzacq AS, Costantini P, Vieira H, Loeffler M, Molle G, Kroemer G.

Oncogene. 2000 Dec 14;19(54):6342-50.

PMID:
11175349
40.

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

Ferri KF, Jacotot E, Blanco J, Esté JA, Zamzami N, Susin SA, Xie Z, Brothers G, Reed JC, Penninger JM, Kroemer G.

J Exp Med. 2000 Oct 16;192(8):1081-92.

41.

Two distinct pathways leading to nuclear apoptosis.

Susin SA, Daugas E, Ravagnan L, Samejima K, Zamzami N, Loeffler M, Costantini P, Ferri KF, Irinopoulou T, Prévost MC, Brothers G, Mak TW, Penninger J, Earnshaw WC, Kroemer G.

J Exp Med. 2000 Aug 21;192(4):571-80.

42.

Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria.

Zamzami N, Métivier D, Kroemer G.

Methods Enzymol. 2000;322:208-13. No abstract available.

PMID:
10914018
43.

Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis.

Daugas E, Nochy D, Ravagnan L, Loeffler M, Susin SA, Zamzami N, Kroemer G.

FEBS Lett. 2000 Jul 7;476(3):118-23. Review.

44.

Proteasome activation as a critical event of thymocyte apoptosis.

Dallaporta B, Pablo M, Maisse C, Daugas E, Loeffler M, Zamzami N, Kroemer G.

Cell Death Differ. 2000 Apr;7(4):368-73.

45.

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.

Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N, Prévost MC, Leber B, Andrews D, Penninger J, Kroemer G.

FASEB J. 2000 Apr;14(5):729-39.

PMID:
10744629
46.

Mitochondrial membrane permeabilization during the apoptotic process.

Jacotot E, Costantini P, Laboureau E, Zamzami N, Susin SA, Kroemer G.

Ann N Y Acad Sci. 1999;887:18-30. Review.

PMID:
10668461
47.

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.

Brenner C, Cadiou H, Vieira HL, Zamzami N, Marzo I, Xie Z, Leber B, Andrews D, Duclohier H, Reed JC, Kroemer G.

Oncogene. 2000 Jan 20;19(3):329-36.

48.

Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis.

Costantini P, Belzacq AS, Vieira HL, Larochette N, de Pablo MA, Zamzami N, Susin SA, Brenner C, Kroemer G.

Oncogene. 2000 Jan 13;19(2):307-14.

49.

The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.

Marchetti P, Zamzami N, Joseph B, Schraen-Maschke S, Méreau-Richard C, Costantini P, Métivier D, Susin SA, Kroemer G, Formstecher P.

Cancer Res. 1999 Dec 15;59(24):6257-66.

50.

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

Jacotot E, Ravagnan L, Loeffler M, Ferri KF, Vieira HL, Zamzami N, Costantini P, Druillennec S, Hoebeke J, Briand JP, Irinopoulou T, Daugas E, Susin SA, Cointe D, Xie ZH, Reed JC, Roques BP, Kroemer G.

J Exp Med. 2000 Jan 3;191(1):33-46.

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