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Items: 15


Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.

Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG.

Sci Transl Med. 2019 Jun 26;11(498). pii: eaat8549. doi: 10.1126/scitranslmed.aat8549.


Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells.

Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T.

BMC Cancer. 2019 Mar 21;19(1):253. doi: 10.1186/s12885-019-5455-1.


Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity.

Guo XJ, Dash P, Crawford JC, Allen EK, Zamora AE, Boyd DF, Duan S, Bajracharya R, Awad WA, Apiwattanakul N, Vogel P, Kanneganti TD, Thomas PG.

Immunity. 2018 Sep 18;49(3):531-544.e6. doi: 10.1016/j.immuni.2018.07.011. Epub 2018 Aug 28.


Hitting the Target: How T Cells Detect and Eliminate Tumors.

Zamora AE, Crawford JC, Thomas PG.

J Immunol. 2018 Jan 15;200(2):392-399. doi: 10.4049/jimmunol.1701413. Review.


Transcription factor ZNF148 is a negative regulator of human muscle differentiation.

Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T.

Sci Rep. 2017 Aug 15;7(1):8138. doi: 10.1038/s41598-017-08267-5.


SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.

Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG.

Nat Med. 2017 Aug;23(8):975-983. doi: 10.1038/nm.4370. Epub 2017 Jul 17.


Licensing delineates helper and effector NK cell subsets during viral infection.

Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ.

JCI Insight. 2017 May 18;2(10). pii: 87032. doi: 10.1172/jci.insight.87032. eCollection 2017 May 18.


Cell-Intrinsic Barriers of T Cell-Based Immunotherapy.

Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA.

Trends Mol Med. 2016 Dec;22(12):1000-1011. doi: 10.1016/j.molmed.2016.10.002. Epub 2016 Nov 4. Review.


Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies.

Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ.

Clin Cancer Res. 2016 Sep 1;22(17):4328-40. doi: 10.1158/1078-0432.CCR-15-3026. Epub 2016 Mar 15.


Models to Study NK Cell Biology and Possible Clinical Application.

Zamora AE, Grossenbacher SK, Aguilar EG, Murphy WJ.

Curr Protoc Immunol. 2015 Aug 3;110:14.37.1-14.37.14. doi: 10.1002/0471142735.im1437s110. Review.


Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help.

Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ.

PLoS One. 2014 Aug 13;9(8):e102709. doi: 10.1371/journal.pone.0102709. eCollection 2014.


Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy.

Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ.

J Exp Med. 2013 Oct 21;210(11):2223-37. doi: 10.1084/jem.20131219. Epub 2013 Sep 30.


Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function.

Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ.

Clin Exp Immunol. 2014 Jan;175(1):79-91. doi: 10.1111/cei.12186.


Immunoediting and antigen loss: overcoming the achilles heel of immunotherapy with antigen non-specific therapies.

Monjazeb AM, Zamora AE, Grossenbacher SK, Mirsoian A, Sckisel GD, Murphy WJ.

Front Oncol. 2013 Jul 26;3:197. doi: 10.3389/fonc.2013.00197. eCollection 2013.


Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses.

Sungur CM, Tang-Feldman YJ, Zamora AE, Alvarez M, Pomeroy C, Murphy WJ.

Blood. 2013 Aug 22;122(8):1518-21. doi: 10.1182/blood-2013-02-483503. Epub 2013 Jul 1.

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