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Items: 25


Potential Therapeutic Targets for Lung Repair During Human Ex Vivo Lung Perfusion.

Wong A, Zamel R, Yeung J, Bader GD, Dos Santos CC, Bai X, Wang Y, Keshavjee S, Liu M.

Eur Respir J. 2020 Feb 14. pii: 1902222. doi: 10.1183/13993003.02222-2019. [Epub ahead of print]


Variation at DENND1B and Asthma on the Island of Tristan da Cunha.

Duffy DL, Siminovitch KA, Zamel R, Chapman KR, Martin NG, Zamel N.

Twin Res Hum Genet. 2019 Oct;22(5):277-282. doi: 10.1017/thg.2019.82. Epub 2019 Oct 14.


Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation?

Cypel M, Yeung JC, Donahoe L, Chen M, Zamel R, Hoetzenecker K, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Keshavjee S.

J Thorac Cardiovasc Surg. 2019 Sep 9. pii: S0022-5223(19)31732-5. doi: 10.1016/j.jtcvs.2019.06.123. [Epub ahead of print]


Neutrophil extracellular traps in ex vivo lung perfusion perfusate predict the clinical outcome of lung transplant recipients.

Caldarone L, Mariscal A, Sage A, Khan M, Juvet S, Martinu T, Zamel R, Cypel M, Liu M, Palaniyar N, Keshavjee S.

Eur Respir J. 2019 Apr 4;53(4). pii: 1801736. doi: 10.1183/13993003.01736-2018. Print 2019 Apr. No abstract available.


Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting.

Kim H, Zamel R, Bai XH, Lu C, Keshavjee S, Keshavjee S, Liu M.

Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L595-L608. doi: 10.1152/ajplung.00069.2018. Epub 2018 Jul 19.


Towards donor lung recovery-gene expression changes during ex vivo lung perfusion of human lungs.

Yeung JC, Zamel R, Klement W, Bai XH, Machuca TN, Waddell TK, Liu M, Cypel M, Keshavjee S.

Am J Transplant. 2018 Jun;18(6):1518-1526. doi: 10.1111/ajt.14700. Epub 2018 Mar 30.


Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes.

Hsin MK, Zamel R, Cypel M, Wishart D, Han B, Keshavjee S, Liu M.

Ann Surg. 2018 Jan;267(1):196-197. doi: 10.1097/SLA.0000000000002016.


Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation.

Hashimoto K, Cypel M, Juvet S, Saito T, Zamel R, Machuca TN, Hsin M, Kim H, Waddell TK, Liu M, Keshavjee S.

J Heart Lung Transplant. 2017 Jun 21. pii: S1053-2498(17)31870-3. doi: 10.1016/j.healun.2017.06.005. [Epub ahead of print]


Soluble Adhesion Molecules During Ex Vivo Lung Perfusion Are Associated With Posttransplant Primary Graft Dysfunction.

Hashimoto K, Cypel M, Kim H, Machuca TN, Nakajima D, Chen M, Hsin MK, Zamel R, Azad S, Waddell TK, Liu M, Keshavjee S.

Am J Transplant. 2017 May;17(5):1396-1404. doi: 10.1111/ajt.14160. Epub 2017 Feb 1.


Importance of left atrial pressure during ex vivo lung perfusion.

Linacre V, Cypel M, Machuca T, Nakajima D, Hashimoto K, Zamel R, Chen M, Iskender I, Dos Santos P, Waddell TK, Liu M, Keshavjee S.

J Heart Lung Transplant. 2016 Jun;35(6):808-14. doi: 10.1016/j.healun.2016.02.008. Epub 2016 Mar 10.


Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.

Hashimoto K, Besla R, Zamel R, Juvet S, Kim H, Azad S, Waddell TK, Cypel M, Liu M, Keshavjee S.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):97-105. doi: 10.1164/rccm.201510-2115OC.


Fractal circuit sensors enable rapid quantification of biomarkers for donor lung assessment for transplantation.

Sage AT, Besant JD, Mahmoudian L, Poudineh M, Bai X, Zamel R, Hsin M, Sargent EH, Cypel M, Liu M, Keshavjee S, Kelley SO.

Sci Adv. 2015 Aug 28;1(7):e1500417. doi: 10.1126/sciadv.1500417. eCollection 2015 Aug.


XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration.

Toba H, Wang Y, Bai X, Zamel R, Cho HR, Liu H, Lira A, Keshavjee S, Liu M.

Oncotarget. 2015 Oct 13;6(31):30803-17. doi: 10.18632/oncotarget.5062.


The role of the endothelin-1 pathway as a biomarker for donor lung assessment in clinical ex vivo lung perfusion.

Machuca TN, Cypel M, Zhao Y, Grasemann H, Tavasoli F, Yeung JC, Bonato R, Chen M, Zamel R, Chun YM, Guan Z, de Perrot M, Waddell TK, Liu M, Keshavjee S.

J Heart Lung Transplant. 2015 Jun;34(6):849-57. doi: 10.1016/j.healun.2015.01.003. Epub 2015 Jan 16.


Potential role of CC chemokine receptor 6 in prediction of late-onset cytomegalovirus infection following solid organ transplant.

Camargo JF, Resende MR, Zamel R, Klement W, Bhimji A, Huibner S, Kumar D, Humar A, Jurisica I, Keshavjee S, Kaul R, Husain S.

Clin Transplant. 2015 Jun;29(6):492-8. doi: 10.1111/ctr.12531. Epub 2015 Apr 22.


Protein expression profiling predicts graft performance in clinical ex vivo lung perfusion.

Machuca TN, Cypel M, Yeung JC, Bonato R, Zamel R, Chen M, Azad S, Hsin MK, Saito T, Guan Z, Waddell TK, Liu M, Keshavjee S.

Ann Surg. 2015 Mar;261(3):591-7. doi: 10.1097/SLA.0000000000000974.


Distinct expression patterns of alveolar "alarmins" in subtypes of chronic lung allograft dysfunction.

Saito T, Liu M, Binnie M, Sato M, Hwang D, Azad S, Machuca TN, Zamel R, Waddell TK, Cypel M, Keshavjee S.

Am J Transplant. 2014 Jun;14(6):1425-32. doi: 10.1111/ajt.12718. Epub 2014 May 1.


Metabolomic heterogeneity of pulmonary arterial hypertension.

Zhao Y, Peng J, Lu C, Hsin M, Mura M, Wu L, Chu L, Zamel R, Machuca T, Waddell T, Liu M, Keshavjee S, Granton J, de Perrot M.

PLoS One. 2014 Feb 12;9(2):e88727. doi: 10.1371/journal.pone.0088727. eCollection 2014.


Elevated CXCL10 (IP-10) in bronchoalveolar lavage fluid is associated with acute cellular rejection after human lung transplantation.

Husain S, Resende MR, Rajwans N, Zamel R, Pilewski JM, Crespo MM, Singer LG, McCurry KR, Kolls JK, Keshavjee S, Liles WC.

Transplantation. 2014 Jan 15;97(1):90-7. doi: 10.1097/TP.0b013e3182a6ee0a.


PKC activation induces inflammatory response and cell death in human bronchial epithelial cells.

Kim H, Zamel R, Bai XH, Liu M.

PLoS One. 2013 May 17;8(5):e64182. doi: 10.1371/journal.pone.0064182. Print 2013.


Ribonucleic acid microarray analysis from lymph node samples obtained by endobronchial ultrasonography-guided transbronchial needle aspiration.

Nakajima T, Zamel R, Anayama T, Kimura H, Yoshino I, Keshavjee S, Yasufuku K.

Ann Thorac Surg. 2012 Dec;94(6):2097-101. doi: 10.1016/j.athoracsur.2012.09.004.


Abetalipoproteinemia: two case reports and literature review.

Zamel R, Khan R, Pollex RL, Hegele RA.

Orphanet J Rare Dis. 2008 Jul 8;3:19. doi: 10.1186/1750-1172-3-19. Review.


Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme.

Zamel R, Poon A, Jaikaran D, Andersen A, Olive J, De Abreu D, Collins RA.

Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1467-72. Epub 2004 Jan 30.


Okadaic acid-induced actin assembly in neutrophils: role of protein phosphatases.

Downey GP, Takai A, Zamel R, Grinstein S, Chan CK.

J Cell Physiol. 1993 Jun;155(3):505-19.


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