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Items: 25


Metastatic squamous cell carcinoma of known and unknown primary origin treated with axillary or inguinal lymphadenectomy.

Wach MM, van Beek E, Ayabe R, Ruff S, Brown Z, Goldman DA, Zambirinis CP, Gholami S, Pulitzer M, Hernandez J, Coit D.

Am J Surg. 2018 Nov;216(5):963-968. doi: 10.1016/j.amjsurg.2018.06.006. Epub 2018 Jun 20.


The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression.

Pushalkar S, Hundeyin M, Daley D, Zambirinis CP, Kurz E, Mishra A, Mohan N, Aykut B, Usyk M, Torres LE, Werba G, Zhang K, Guo Y, Li Q, Akkad N, Lall S, Wadowski B, Gutierrez J, Kochen Rossi JA, Herzog JW, Diskin B, Torres-Hernandez A, Leinwand J, Wang W, Taunk PS, Savadkar S, Janal M, Saxena A, Li X, Cohen D, Sartor RB, Saxena D, Miller G.

Cancer Discov. 2018 Apr;8(4):403-416. doi: 10.1158/2159-8290.CD-17-1134. Epub 2018 Mar 22.


Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer.

Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR.

HPB (Oxford). 2018 Jul;20(7):597-604. doi: 10.1016/j.hpb.2017.12.010. Epub 2018 Jan 12.


Cancer Manipulation of Host Physiology: Lessons from Pancreatic Cancer.

Zambirinis CP, Miller G.

Trends Mol Med. 2017 May;23(5):465-481. doi: 10.1016/j.molmed.2017.03.003. Epub 2017 Apr 8. Review.


Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

Daley D, Mani VR, Mohan N, Akkad N, Ochi A, Heindel DW, Lee KB, Zambirinis CP, Pandian GSB, Savadkar S, Torres-Hernandez A, Nayak S, Wang D, Hundeyin M, Diskin B, Aykut B, Werba G, Barilla RM, Rodriguez R, Chang S, Gardner L, Mahal LK, Ueberheide B, Miller G.

Nat Med. 2017 May;23(5):556-567. doi: 10.1038/nm.4314. Epub 2017 Apr 10.


γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.

Daley D, Zambirinis CP, Seifert L, Akkad N, Mohan N, Werba G, Barilla R, Torres-Hernandez A, Hundeyin M, Mani VRK, Avanzi A, Tippens D, Narayanan R, Jang JE, Newman E, Pillarisetty VG, Dustin ML, Bar-Sagi D, Hajdu C, Miller G.

Cell. 2016 Sep 8;166(6):1485-1499.e15. doi: 10.1016/j.cell.2016.07.046. Epub 2016 Aug 25.


The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression.

Seifert L, Werba G, Tiwari S, Giao Ly NN, Alothman S, Alqunaibit D, Avanzi A, Barilla R, Daley D, Greco SH, Torres-Hernandez A, Pergamo M, Ochi A, Zambirinis CP, Pansari M, Rendon M, Tippens D, Hundeyin M, Mani VR, Hajdu C, Engle D, Miller G.

Nature. 2016 Apr 14;532(7598):245-9. doi: 10.1038/nature17403. Epub 2016 Apr 6.


Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways.

Seifert L, Deutsch M, Alothman S, Alqunaibit D, Werba G, Pansari M, Pergamo M, Ochi A, Torres-Hernandez A, Levie E, Tippens D, Greco SH, Tiwari S, Ly NNG, Eisenthal A, van Heerden E, Avanzi A, Barilla R, Zambirinis CP, Rendon M, Daley D, Pachter HL, Hajdu C, Miller G.

Cell Rep. 2015 Dec 1;13(9):1909-1921. doi: 10.1016/j.celrep.2015.10.058. Epub 2015 Nov 19.


TLR9 ligation in pancreatic stellate cells promotes tumorigenesis.

Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, Seifert L, Daley D, Greco SH, Deutsch M, Jonnadula S, Torres-Hernandez A, Tippens D, Pushalkar S, Eisenthal A, Saxena D, Ahn J, Hajdu C, Engle DD, Tuveson D, Miller G.

J Exp Med. 2015 Nov 16;212(12):2077-94. doi: 10.1084/jem.20142162. Epub 2015 Oct 19.


Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.

Deutsch M, Graffeo CS, Rokosh R, Pansari M, Ochi A, Levie EM, Van Heerden E, Tippens DM, Greco S, Barilla R, Tomkötter L, Zambirinis CP, Avanzi N, Gulati R, Pachter HL, Torres-Hernandez A, Eisenthal A, Daley D, Miller G.

Cell Death Dis. 2015 May 7;6:e1759. doi: 10.1038/cddis.2015.126.


Adoptive immunotherapy of epithelial ovarian cancer with Vγ9Vδ2 T cells, potentiated by liposomal alendronic acid.

Parente-Pereira AC, Shmeeda H, Whilding LM, Zambirinis CP, Foster J, van der Stegen SJ, Beatson R, Zabinski T, Brewig N, Sosabowski JK, Mather S, Ghaem-Maghami S, Gabizon A, Maher J.

J Immunol. 2014 Dec 1;193(11):5557-66. doi: 10.4049/jimmunol.1402200. Epub 2014 Oct 22.


Pancreatic cancer, inflammation, and microbiome.

Zambirinis CP, Pushalkar S, Saxena D, Miller G.

Cancer J. 2014 May-Jun;20(3):195-202. doi: 10.1097/PPO.0000000000000045. Review.


Interleukin 17-producing γδT cells promote hepatic regeneration in mice.

Rao R, Graffeo CS, Gulati R, Jamal M, Narayan S, Zambirinis CP, Barilla R, Deutsch M, Greco SH, Ochi A, Tomkötter L, Blobstein R, Avanzi A, Tippens DM, Gelbstein Y, Van Heerden E, Miller G.

Gastroenterology. 2014 Aug;147(2):473-84.e2. doi: 10.1053/j.gastro.2014.04.042. Epub 2014 May 4.


Induction of TRIF- or MYD88-dependent pathways perturbs cell cycle regulation in pancreatic cancer.

Zambirinis CP, Ochi A, Barilla R, Greco S, Deutsch M, Miller G.

Cell Cycle. 2013 Apr 15;12(8):1153-4. doi: 10.4161/cc.24488. Epub 2013 Apr 2. No abstract available.


Role of fatty-acid synthesis in dendritic cell generation and function.

Rehman A, Hemmert KC, Ochi A, Jamal M, Henning JR, Barilla R, Quesada JP, Zambirinis CP, Tang K, Ego-Osuala M, Rao RS, Greco S, Deutsch M, Narayan S, Pachter HL, Graffeo CS, Acehan D, Miller G.

J Immunol. 2013 May 1;190(9):4640-9. doi: 10.4049/jimmunol.1202312. Epub 2013 Mar 27.


Signaling via MYD88 in the pancreatic tumor microenvironment: A double-edged sword.

Zambirinis CP, Miller G.

Oncoimmunology. 2013 Jan 1;2(1):e22567.


Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice.

Henning JR, Graffeo CS, Rehman A, Fallon NC, Zambirinis CP, Ochi A, Barilla R, Jamal M, Deutsch M, Greco S, Ego-Osuala M, Bin-Saeed U, Rao RS, Badar S, Quesada JP, Acehan D, Miller G.

Hepatology. 2013 Aug;58(2):589-602. doi: 10.1002/hep.26267. Epub 2013 Jun 24.


The impact of the stromal cell-derived factor-1-3'A and E-selectin S128R polymorphisms on breast cancer.

Kontogianni P, Zambirinis CP, Theodoropoulos G, Gazouli M, Michalopoulos NV, Flessas J, Liberi M, Zografos GC.

Mol Biol Rep. 2013 Jan;40(1):43-50. doi: 10.1007/s11033-012-1989-x. Epub 2012 Nov 6.


Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.

Ochi A, Graffeo CS, Zambirinis CP, Rehman A, Hackman M, Fallon N, Barilla RM, Henning JR, Jamal M, Rao R, Greco S, Deutsch M, Medina-Zea MV, Bin Saeed U, Ego-Osuala MO, Hajdu C, Miller G.

J Clin Invest. 2012 Nov;122(11):4118-29.


MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells.

Ochi A, Nguyen AH, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, Zambirinis CP, Fallon NC, Rehman A, Pylayeva-Gupta Y, Badar S, Hajdu CH, Frey AB, Bar-Sagi D, Miller G.

J Exp Med. 2012 Aug 27;209(9):1671-87. doi: 10.1084/jem.20111706. Epub 2012 Aug 20.


Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver.

Ibrahim J, Nguyen AH, Rehman A, Ochi A, Jamal M, Graffeo CS, Henning JR, Zambirinis CP, Fallon NC, Barilla R, Badar S, Mitchell A, Rao RS, Acehan D, Frey AB, Miller G.

Gastroenterology. 2012 Oct;143(4):1061-72. doi: 10.1053/j.gastro.2012.06.003. Epub 2012 Jun 12.


Analysis of the stromal cell-derived factor 1-3'A gene polymorphism in pancreatic cancer.

Theodoropoulos GE, Panoussopoulos GS, Michalopoulos NV, Zambirinis CP, Taka S, Stamopoulos P, Gazouli M, Zografos G.

Mol Med Rep. 2010 Jul-Aug;3(4):693-8. doi: 10.3892/mmr_00000319.


Gorham-Stout disease.

Mavrogenis AF, Zambirinis CP, Dimitriadis PA, Tsakanikas A, Papagelopoulos PJ.

J Surg Orthop Adv. 2010 Summer;19(2):85-90.


Undefined familial colorectal cancer.

Zambirinis CP, Theodoropoulos G, Gazouli M.

World J Gastrointest Oncol. 2009 Oct 15;1(1):12-20. doi: 10.4251/wjgo.v1.i1.12.


P53 and EGFR expression in colorectal cancer: a reappraisal of 'old' tissue markers in patients with long follow-up.

Theodoropoulos GE, Karafoka E, Papailiou JG, Stamopoulos P, Zambirinis CP, Bramis K, Panoussopoulos SG, Leandros E, Bramis J.

Anticancer Res. 2009 Feb;29(2):785-91.

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