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Nerve growth factor (NGF) has an anti-tumor effects through perivascular innervation of neovessels in HT1080 fibrosarcoma and HepG2 hepatitis tumor in nude mice.

Kawasaki H, Goda M, Fukuhara S, Hashikawa-Hobara N, Zamami Y, Takatori S.

J Pharmacol Sci. 2019 May;140(1):1-7. doi: 10.1016/j.jphs.2019.02.011. Epub 2019 May 23.


Iron accumulation causes impaired myogenesis correlated with MAPK signaling pathway inhibition by oxidative stress.

Ikeda Y, Satoh A, Horinouchi Y, Hamano H, Watanabe H, Imao M, Imanishi M, Zamami Y, Takechi K, Izawa-Ishizawa Y, Miyamoto L, Hirayama T, Nagasawa H, Ishizawa K, Aihara KI, Tsuchiya K, Tamaki T.

FASEB J. 2019 May 30:fj201802724RR. doi: 10.1096/fj.201802724RR. [Epub ahead of print]


Factors Affecting the Absorption of Midazolam to the Extracorporeal Membrane Oxygenation Circuit.

Iida A, Naito H, Yorifuji T, Zamami Y, Yamada A, Koga T, Imai T, Sendo T, Nakao A, Ichiba S.

Acta Med Okayama. 2019 Apr;73(2):101-107. doi: 10.18926/AMO/56645.


Association between rapid antigen detection tests and antibiotics for acute pharyngitis in Japan: A retrospective observational study.

Teratani Y, Hagiya H, Koyama T, Ohshima A, Zamami Y, Tatebe Y, Tasaka K, Shinomiya K, Kitamura Y, Sendo T, Hinotsu S, Kano MR.

J Infect Chemother. 2019 Apr;25(4):267-272. doi: 10.1016/j.jiac.2018.12.005. Epub 2019 Jan 12.


Pharmacovigilance evaluation of the relationship between impaired glucose metabolism and BCR-ABL inhibitor use by using an adverse drug event reporting database.

Okada N, Niimura T, Zamami Y, Hamano H, Ishida S, Goda M, Takechi K, Chuma M, Imanishi M, Ishizawa K.

Cancer Med. 2019 Jan;8(1):174-181. doi: 10.1002/cam4.1920. Epub 2018 Dec 18.


Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation.

Zamami Y, Kouno Y, Niimura T, Chuma M, Imai T, Mitsui M, Koyama T, Kayano M, Okada N, Hamano H, Goda M, Imanishi M, Takechi K, Horinouchi Y, Kondo Y, Yanagawa H, Kitamura Y, Sendo T, Ujike Y, Ishizawa K.

Pharmazie. 2018 Dec 1;73(12):740-743. doi: 10.1691/ph.2018.8711.


Association Between Immune-Related Adverse Events and Clinical Efficacy in Patients with Melanoma Treated With Nivolumab: A Multicenter Retrospective Study.

Okada N, Kawazoe H, Takechi K, Matsudate Y, Utsunomiya R, Zamami Y, Goda M, Imanishi M, Chuma M, Hidaka N, Sayama K, Kubo Y, Tanaka A, Ishizawa K.

Clin Ther. 2019 Jan;41(1):59-67. doi: 10.1016/j.clinthera.2018.11.004. Epub 2018 Dec 7.


Trends in incidence and mortality of tuberculosis in Japan: a population-based study, 1997-2016.

Hagiya H, Koyama T, Zamami Y, Minato Y, Tatebe Y, Mikami N, Teratani Y, Ohshima A, Shinomiya K, Kitamura Y, Sendo T, Hinotsu S, Tomono K, Kano MR.

Epidemiol Infect. 2018 Nov 9:1-10. doi: 10.1017/S095026881800290X. [Epub ahead of print]


Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.

Kondo M, Imanishi M, Fukushima K, Ikuto R, Murai Y, Horinouchi Y, Izawa-Ishizawa Y, Goda M, Zamami Y, Takechi K, Chuma M, Ikeda Y, Fujino H, Tsuchiya K, Ishizawa K.

Am J Hypertens. 2019 Feb 12;32(3):249-256. doi: 10.1093/ajh/hpy157.


Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses.

Izawa-Ishizawa Y, Imanishi M, Zamami Y, Toya H, Nagao T, Morishita M, Tsuneyama K, Horinouchi Y, Kihira Y, Takechi K, Ikeda Y, Tsuchiya K, Yoshizumi M, Tamaki T, Ishizawa K.

J Hypertens. 2019 Jan;37(1):73-83. doi: 10.1097/HJH.0000000000001898.


Trends in Polypharmacy in Japan: A Nationwide Retrospective Study.

Onoue H, Koyama T, Zamami Y, Hagiya H, Tatebe Y, Mikami N, Shinomiya K, Kitamura Y, Hinotsu S, Sendo T, Ouchi Y, Kano MR.

J Am Geriatr Soc. 2018 Dec;66(12):2267-2273. doi: 10.1111/jgs.15569. Epub 2018 Oct 6.


Pattern of antibiotic prescriptions for outpatients with acute respiratory tract infections in Japan, 2013-15: a retrospective observational study.

Teratani Y, Hagiya H, Koyama T, Adachi M, Ohshima A, Zamami Y, Tanaka HY, Tatebe Y, Tasaka K, Mikami N, Shinomiya K, Kitamura Y, Kano MR, Hinotsu S, Sendo T.

Fam Pract. 2018 Sep 29. doi: 10.1093/fampra/cmy094. [Epub ahead of print]


Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.

Imanishi M, Izawa-Ishizawa Y, Sakurada T, Kohara Y, Horinouchi Y, Sairyo E, Zamami Y, Takechi K, Chuma M, Fukushima K, Ikeda Y, Fujino H, Yoshizumi M, Tsuchiya K, Tamaki T, Ishizawa K.

Pharmacology. 2018;102(5-6):287-299. doi: 10.1159/000492577. Epub 2018 Sep 25.


Development and pharmacist-mediated use of tools for monitoring atypical antipsychotic-induced side effects related to blood glucose levels.

Ishida S, Takechi K, Bando H, Imanishi M, Zamami Y, Chuma M, Yanagawa H, Kirino Y, Nakamura T, Teraoka K, Ishizawa K.

Pharmacoepidemiol Drug Saf. 2018 Dec;27(12):1379-1384. doi: 10.1002/pds.4656. Epub 2018 Sep 17.


Irinotecan-induced neutropenia is reduced by oral alkalization drugs: analysis using retrospective chart reviews and the spontaneous reporting database.

Hamano H, Mitsui M, Zamami Y, Takechi K, Nimura T, Okada N, Fukushima K, Imanishi M, Chuma M, Horinouchi Y, Izawa-Ishizawa Y, Kirino Y, Nakamura T, Teraoka K, Ikeda Y, Fujino H, Yanagawa H, Tamaki T, Ishizawa K.

Support Care Cancer. 2019 Mar;27(3):849-856. doi: 10.1007/s00520-018-4367-y. Epub 2018 Jul 31.


Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis.

Horinouchi Y, Ikeda Y, Fukushima K, Imanishi M, Hamano H, Izawa-Ishizawa Y, Zamami Y, Takechi K, Miyamoto L, Fujino H, Ishizawa K, Tsuchiya K, Tamaki T.

Sci Rep. 2018 Jul 18;8(1):10858. doi: 10.1038/s41598-018-29008-2.


Administration of Kampo medicine through a tube at an advanced critical care center.

Niimura T, Zamami Y, Imai T, Ito T, Sagara H, Hiroyuki H, Esumi S, Takechi K, Imanishi M, Koyama T, Amano M, Kurata N, Kitamura Y, Nakura H, Sendo T, Ishizawa K.

J Med Invest. 2018;65(1.2):32-36. doi: 10.2152/jmi.65.32.


Evaluation of the Benefits of De-Escalation for Patients with Sepsis in the Emergency Intensive Care Unit.

Niimura T, Zamami Y, Imai T, Nagao K, Kayano M, Sagara H, Goda M, Okada N, Chuma M, Takechi K, Imanishi M, Koyama T, Koga T, Nakura H, Sendo T, Ishizawa K.

J Pharm Pharm Sci. 2018;21(1):54-59. doi: 10.29173/jpps29737.


Potential Usefulness of Early Potassium Supplementation for Preventing Severe Hypokalemia Induced by Liposomal Amphotericin B in Hematologic Patients: A Retrospective Study.

Okada N, Azuma M, Imanishi M, Zamami Y, Kirino Y, Nakamura T, Teraoka K, Abe M, Ishizawa K.

Clin Ther. 2018 Feb;40(2):252-260. doi: 10.1016/j.clinthera.2017.12.006. Epub 2018 Jan 2.


Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest.

Niimura T, Zamami Y, Koyama T, Izawa-Ishizawa Y, Miyake M, Koga T, Harada K, Ohshima A, Imai T, Kondo Y, Imanishi M, Takechi K, Fukushima K, Horinouchi Y, Ikeda Y, Fujino H, Tsuchiya K, Tamaki T, Hinotsu S, Kano MR, Ishizawa K.

Sci Rep. 2017 Dec 20;7(1):17919. doi: 10.1038/s41598-017-17686-3.


[Drug Repositioning Research Utilizing a Large-scale Medical Claims Database to Improve Survival Rates after Cardiopulmonary Arrest].

Zamami Y, Niimura T, Takechi K, Imanishi M, Koyama T, Ishizawa K.

Yakugaku Zasshi. 2017;137(12):1439-1442. doi: 10.1248/yakushi.17-00139-3. Review. Japanese.


Trends in the medication reviews of community pharmacies in Japan: a nationwide retrospective study.

Koyama T, Onoue H, Ohshima A, Tanaka Y, Tatebe Y, Zamami Y, Shinomiya K, Kitamura Y.

Int J Clin Pharm. 2018 Feb;40(1):101-108. doi: 10.1007/s11096-017-0559-7. Epub 2017 Nov 30.


Patterns of CT use in Japan, 2014: A nationwide cross-sectional study.

Koyama T, Zamami Y, Ohshima A, Teratani Y, Shinomiya K, Kitamura Y.

Eur J Radiol. 2017 Dec;97:96-100. doi: 10.1016/j.ejrad.2017.10.023. Epub 2017 Oct 31.


The uremic toxin indoxyl sulfate interferes with iron metabolism by regulating hepcidin in chronic kidney disease.

Hamano H, Ikeda Y, Watanabe H, Horinouchi Y, Izawa-Ishizawa Y, Imanishi M, Zamami Y, Takechi K, Miyamoto L, Ishizawa K, Tsuchiya K, Tamaki T.

Nephrol Dial Transplant. 2018 Apr 1;33(4):586-597. doi: 10.1093/ndt/gfx252.


Meta-analysis of the efficacies of amiodarone and nifekalant in shock-resistant ventricular fibrillation and pulseless ventricular tachycardia.

Sato S, Zamami Y, Imai T, Tanaka S, Koyama T, Niimura T, Chuma M, Koga T, Takechi K, Kurata Y, Kondo Y, Izawa-Ishizawa Y, Sendo T, Nakura H, Ishizawa K.

Sci Rep. 2017 Oct 4;7(1):12683. doi: 10.1038/s41598-017-13073-0.


Psychiatric Patients with Antipsychotic Drug-Induced Hyperprolactinemia and Menstruation Disorders.

Takechi K, Yoshioka Y, Kawazoe H, Tanaka M, Takatori S, Kobayashi M, Matsuoka I, Yanagawa H, Zamami Y, Imanishi M, Ishizawa K, Tanaka A, Araki H.

Biol Pharm Bull. 2017;40(10):1775-1778. doi: 10.1248/bpb.b17-00053.


Pharmacological approach for drug repositioning against cardiorenal diseases.

Zamami Y, Imanishi M, Takechi K, Ishizawa K.

J Med Invest. 2017;64(3.4):197-201. doi: 10.2152/jmi.64.197. Review.


Dietary iron restriction alleviates renal tubulointerstitial injury induced by protein overload in mice.

Ikeda Y, Horinouchi Y, Hamano H, Hirayama T, Kishi S, Izawa-Ishizawa Y, Imanishi M, Zamami Y, Takechi K, Miyamoto L, Ishizawa K, Aihara KI, Nagasawa H, Tsuchiya K, Tamaki T.

Sci Rep. 2017 Sep 6;7(1):10621. doi: 10.1038/s41598-017-11089-0.


Kamishoyosan and Shakuyakukanzoto promote recovery from paclitaxel-induced neurite retraction in PC12 cells.

Konaka K, Moriyama K, Sakurada T, Okada N, Imanishi M, Zamami Y, Kawazoe K, Fushitani S, Ishizawa K.

J Pharm Health Care Sci. 2017 Jul 21;3:20. doi: 10.1186/s40780-017-0090-y. eCollection 2017.


Evaluation of factors associated with the achievement of an optimal teicoplanin trough concentration

Takechi K, Yanagawa H, Zamami Y, Ishizawa K, Tanaka A, Araki H.

Int J Clin Pharmacol Ther. 2017 Aug;55(8):672-677. doi: 10.5414/CP203009.


HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice.

Hashikawa N, Utaka Y, Ogawa T, Tanoue R, Morita Y, Yamamoto S, Yamaguchi S, Kayano M, Zamami Y, Hashikawa-Hobara N.

Sci Adv. 2017 May 31;3(5):e1603014. doi: 10.1126/sciadv.1603014. eCollection 2017 May.


Effect of Nerve Growth Factor on Innervation of Perivascular Nerves in Neovasculatures of Mouse Cornea.

Matsuyama A, Takatori S, Sone Y, Ochi E, Goda M, Zamami Y, Hashikawa-Hobara N, Kitamura Y, Kawasaki H.

Biol Pharm Bull. 2017;40(4):396-401. doi: 10.1248/bpb.b16-00583.


Effects of endogenous nitric oxide on adrenergic nerve-mediated vasoconstriction and calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats.

Yamawaki K, Zamami Y, Kawasaki H, Takatori S.

Eur J Pharmacol. 2017 May 5;802:69-75. doi: 10.1016/j.ejphar.2017.02.041. Epub 2017 Feb 27.


Nerve Growth Factor Facilitates the Innervation of Perivascular Nerves in Tumor-Derived Neovasculature in the Mouse Cornea.

Sone Y, Takatori S, Ochi E, Zamami Y, Matsuyama A, Fukuhara S, Goda M, Kitamura Y, Kawasaki H.

Pharmacology. 2017;99(1-2):57-66. doi: 10.1159/000450582. Epub 2016 Oct 1.


Evaluation of pharmaceutical lifesaving skills training oriented pharmaceutical intervention.

Zamami Y, Imai T, Imanishi M, Takechi K, Shiraishi N, Koyama T, Sagara H, Shiino Y, Sendo T, Ishizawa K.

J Pharm Health Care Sci. 2016 Sep 7;2(1):21. doi: 10.1186/s40780-016-0054-7. eCollection 2016.


Pharmaceutical Education Focused on Pharmacotherapy in Emergency Medical Care.

Zamami Y, Koyama T, Imai T, Takemoto A, Sagara H, Sendo T, Nakura H.

Yakugaku Zasshi. 2016;136(7):987-91. doi: 10.1248/yakushi.15-00286-4. Review. Japanese.


Possibility of Pharmacist in Emergency Medical Care: To Bring Up a Familiar Pharmacist for Emergency Care by Fusing Clinical Pharmacist Activity and University Education.

Zamami Y, Koyama T, Nakura H, Enomoto S.

Yakugaku Zasshi. 2016;136(7):965. doi: 10.1248/yakushi.15-00286-F. Japanese. No abstract available.


Vascular responses to compound 48/80 in rat mesenteric vascular beds.

Jin H, Li Z, Takatori S, Koyama T, Jin X, Zamami Y, Kawasaki H, Sun P.

Can J Physiol Pharmacol. 2016 Jun;94(6):620-6. doi: 10.1139/cjpp-2015-0442. Epub 2016 Jan 15.


Muscarinic acetylcholine receptor M1 and M3 subtypes mediate acetylcholine-induced endothelium-independent vasodilatation in rat mesenteric arteries.

Tangsucharit P, Takatori S, Zamami Y, Goda M, Pakdeechote P, Kawasaki H, Takayama F.

J Pharmacol Sci. 2016 Jan;130(1):24-32. doi: 10.1016/j.jphs.2015.12.005. Epub 2016 Jan 8.


Calcitonin gene-related peptide pre-administration acts as a novel antidepressant in stressed mice.

Hashikawa-Hobara N, Ogawa T, Sakamoto Y, Matsuo Y, Ogawa M, Zamami Y, Hashikawa N.

Sci Rep. 2015 Aug 7;5:12559. doi: 10.1038/srep12559.


Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse.

Hashikawa N, Ogawa T, Sakamoto Y, Ogawa M, Matsuo Y, Zamami Y, Hashikawa-Hobara N.

Cell Mol Neurobiol. 2015 Aug;35(6):807-17. doi: 10.1007/s10571-015-0174-x. Epub 2015 Mar 28.


Decreased perivascular CGRP-containing nerves in Otsuka Long-Evans Tokushima Fatty rats with insulin resistance and hypertension.

Takatori S, Fujiwara H, Zamami Y, Hashikawa-Hobara N, Kawasaki H.

Hypertens Res. 2014 May;37(5):398-404. doi: 10.1038/hr.2013.151. Epub 2013 Nov 14.


[Effectiveness of Team-Based Learning (TBL) as a new teaching approach for pharmaceutical care education].

Suno M, Yoshida T, Koyama T, Zamami Y, Miyoshi T, Mizushima T, Tanimoto M.

Yakugaku Zasshi. 2013;133(10):1127-34. Japanese.


Insulin resistance-induced hypertension and a role of perivascular CGRPergic nerves.

Takatori S, Zamami Y, Hashikawa-Hobara N, Kawasaki H.

Curr Protein Pept Sci. 2013 Jun;14(4):275-81. Review.


Do cholinergic nerves innervating rat mesenteric arteries regulate vascular tone?

Tangsucharit P, Takatori S, Sun P, Zamami Y, Goda M, Pakdeechote P, Takayama F, Kawasaki H.

Am J Physiol Regul Integr Comp Physiol. 2012 Dec;303(11):R1147-56. doi: 10.1152/ajpregu.00317.2012. Epub 2012 Oct 10.


Neurogenic vascular responses in male mouse mesenteric vascular beds.

Fujiwara H, Hashikawa-Hobara N, Wake Y, Takatori S, Goda M, Higuchi H, Zamami Y, Tangsucharit P, Kawasaki H.

J Pharmacol Sci. 2012;119(3):260-70. Epub 2012 Jun 28.


Synthesis and antimalarial activity of calothrixins A and B, and their N-alkyl derivatives.

Matsumoto K, Choshi T, Hourai M, Zamami Y, Sasaki K, Abe T, Ishikura M, Hatae N, Iwamura T, Tohyama S, Nobuhiro J, Hibino S.

Bioorg Med Chem Lett. 2012 Jul 15;22(14):4762-4. doi: 10.1016/j.bmcl.2012.05.064. Epub 2012 Jun 4.


The mechanism of calcitonin gene-related peptide-containing nerve innervation.

Hashikawa-Hobara N, Hashikawa N, Zamami Y, Takatori S, Kawasaki H.

J Pharmacol Sci. 2012;119(2):117-21. Epub 2012 May 17.


Adrenergic stimulation-released histamine taken-up in adrenergic nerves induces endothelium-dependent vasodilation in rat mesenteric resistance arteries.

Haruki Y, Takatori S, Hattori S, Zamami Y, Koyama T, Tangsucharit P, Kawasaki H.

J Pharmacol Sci. 2012;118(4):537-42.


Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed.

Tamaki C, Nawa H, Takatori S, Oda S, Sendo T, Zamami Y, Kawasaki H.

J Pharmacol Sci. 2012;118(4):496-505.

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