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Items: 28


Sequential infection experiments for quantifying innate and adaptive immunity during influenza infection.

Yan AWC, Zaloumis SG, Simpson JA, McCaw JM.

PLoS Comput Biol. 2019 Jan 17;15(1):e1006568. doi: 10.1371/journal.pcbi.1006568. eCollection 2019 Jan.


In Silico Investigation of the Decline in Clinical Efficacy of Artemisinin Combination Therapies Due to Increasing Artemisinin and Partner Drug Resistance.

Zaloumis SG, Cao P, Dini S, Davenport MP, Cromer D, Khoury DS, Fowkes FJI, McCaw JM, Simpson JA.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01292-18. doi: 10.1128/AAC.01292-18. Print 2018 Dec.


Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling.

Dini S, Zaloumis S, Cao P, Price RN, Fowkes FJI, van der Pluijm RW, McCaw JM, Simpson JA.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01068-18. doi: 10.1128/AAC.01068-18. Print 2018 Nov.


A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum.

Cao P, Klonis N, Zaloumis S, Dogovski C, Xie SC, Saralamba S, White LJ, Fowkes FJI, Tilley L, Simpson JA, McCaw JM.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00618-17. doi: 10.1128/AAC.00618-17. Print 2017 Dec.


A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection.

Cao P, Klonis N, Zaloumis S, Khoury DS, Cromer D, Davenport MP, Tilley L, Simpson JA, McCaw JM.

J Theor Biol. 2017 Oct 7;430:117-127. doi: 10.1016/j.jtbi.2017.07.017. Epub 2017 Jul 18.


HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.

Warne CD, Zaloumis SG, Bertalli NA, Delatycki MB, Nicoll AJ, McLaren CE, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2017 Apr;32(4):797-802. doi: 10.1111/jgh.13621.


Analysis of ex vivo drug response data of Plasmodium clinical isolates: the pros and cons of different computer programs and online platforms.

Wirjanata G, Handayuni I, Zaloumis SG, Chalfein F, Prayoga P, Kenangalem E, Poespoprodjo JR, Noviyanti R, Simpson JA, Price RN, Marfurt J.

Malar J. 2016 Mar 2;15:137. doi: 10.1186/s12936-016-1173-1.


Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice.

Quinn KM, Zaloumis SG, Cukalac T, Kan WT, Sng XY, Mirams M, Watson KA, McCaw JM, Doherty PC, Thomas PG, Handel A, La Gruta NL.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1333-8. doi: 10.1073/pnas.1525167113. Epub 2016 Jan 19.


Presenting parasitological data: the good, the bad and the error bar.

Zaloumis SG, Fowkes FJ, De Livera A, Simpson JA.

Parasitology. 2015 Sep;142(11):1351-63. doi: 10.1017/S0031182015000748. Epub 2015 Jun 29. Review.


Intervals to Plasmodium falciparum recurrence after anti-malarial treatment in pregnancy: a longitudinal prospective cohort.

Laochan N, Zaloumis SG, Imwong M, Lek-Uthai U, Brockman A, Sriprawat K, Wiladphaingern J, White NJ, Nosten F, McGready R.

Malar J. 2015 May 28;14:221. doi: 10.1186/s12936-015-0745-9.


Population pharmacokinetics of intravenous artesunate: a pooled analysis of individual data from patients with severe malaria.

Zaloumis SG, Tarning J, Krishna S, Price RN, White NJ, Davis TM, McCaw JM, Olliaro P, Maude RJ, Kremsner P, Dondorp A, Gomes M, Barnes K, Simpson JA.

CPT Pharmacometrics Syst Pharmacol. 2014 Nov 5;3:e145. doi: 10.1038/psp.2014.43.


Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.

Zaloumis SG, Allen KJ, Bertalli NA, Turkovic L, Delatycki MB, Nicoll AJ, McLaren CE, English DR, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2015 Apr;30(4):719-25. doi: 10.1111/jgh.12804.


Non-proportional odds multivariate logistic regression of ordinal family data.

Zaloumis SG, Scurrah KJ, Harrap SB, Ellis JA, Gurrin LC.

Biom J. 2015 Mar;57(2):286-303. doi: 10.1002/bimj.201300137. Epub 2014 Oct 7.


Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs.

Simpson JA, Zaloumis S, DeLivera AM, Price RN, McCaw JM.

AAPS J. 2014 Sep;16(5):962-74. doi: 10.1208/s12248-014-9647-y. Epub 2014 Jul 24. Review.


Childhood wheeze phenotypes show less than expected growth in FEV1 across adolescence.

Lodge CJ, Lowe AJ, Allen KJ, Zaloumis S, Gurrin LC, Matheson MC, Axelrad C, Welsh L, Bennett CM, Hopper J, Thomas PS, Hill DJ, Hosking CS, Svanes C, Abramson MJ, Dharmage SC.

Am J Respir Crit Care Med. 2014 Jun 1;189(11):1351-8. doi: 10.1164/rccm.201308-1487OC.


Models for the analysis of repeated continuous outcome measures in clinical trials.

De Livera AM, Zaloumis S, Simpson JA.

Respirology. 2014 Feb;19(2):155-161. doi: 10.1111/resp.12217. Epub 2013 Nov 25. Review. Erratum in: Respirology. 2014 Apr;19(3):461.


Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges.

Patel K, Simpson JA, Batty KT, Zaloumis S, Kirkpatrick CM.

Br J Clin Pharmacol. 2015 Jan;79(1):97-107. doi: 10.1111/bcp.12288. Review.


Early-life risk factors for childhood wheeze phenotypes in a high-risk birth cohort.

Lodge CJ, Zaloumis S, Lowe AJ, Gurrin LC, Matheson MC, Axelrad C, Bennett CM, Hill DJ, Hosking CS, Svanes C, Abramson MJ, Allen KJ, Dharmage SC.

J Pediatr. 2014 Feb;164(2):289-94.e1-2. doi: 10.1016/j.jpeds.2013.09.056. Epub 2013 Nov 14.


Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum.

Simpson JA, Jamsen KM, Anderson TJ, Zaloumis S, Nair S, Woodrow C, White NJ, Nosten F, Price RN.

PLoS One. 2013 Jul 24;8(7):e69505. doi: 10.1371/journal.pone.0069505. Print 2013.


The hope in redefining atopy.

Lowe AJ, Zaloumis S, Dharmage SC.

Clin Exp Allergy. 2013 Jun;43(6):583-5. doi: 10.1111/cea.12127. No abstract available.


Altered temporal response of malaria parasites determines differential sensitivity to artemisinin.

Klonis N, Xie SC, McCaw JM, Crespo-Ortiz MP, Zaloumis SG, Simpson JA, Tilley L.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5157-62. doi: 10.1073/pnas.1217452110. Epub 2013 Feb 19.


Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development.

Zaloumis S, Humberstone A, Charman SA, Price RN, Moehrle J, Gamo-Benito J, McCaw J, Jamsen KM, Smith K, Simpson JA.

Malar J. 2012 Aug 30;11:303. doi: 10.1186/1475-2875-11-303.


Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population data.

Webster RJ, Carter KW, Warrington NM, Loh AM, Zaloumis S, Kuijpers TW, Palmer LJ, Burgner DP.

PLoS One. 2011;6(11):e28004. doi: 10.1371/journal.pone.0028004. Epub 2011 Nov 28.


Association analysis of oestrogen receptor beta gene (ESR2) polymorphisms with female pattern hair loss.

Yip L, Zaloumis S, Irwin D, Severi G, Hopper J, Giles G, Harrap S, Sinclair R, Ellis J.

Br J Dermatol. 2012 May;166(5):1131-4. doi: 10.1111/j.1365-2133.2011.10702.x. Epub 2012 Mar 5. No abstract available.


Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene.

Cobb JE, Zaloumis SG, Scurrah KJ, Harrap SB, Ellis JA.

Exp Dermatol. 2010 Nov;19(11):1026-8. doi: 10.1111/j.1600-0625.2010.01132.x. Epub 2010 Sep 7.


Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss.

Yip L, Zaloumis S, Irwin D, Severi G, Hopper J, Giles G, Harrap S, Sinclair R, Ellis J.

Br J Dermatol. 2009 Aug;161(2):289-94. doi: 10.1111/j.1365-2133.2009.09186.x. Epub 2009 Apr 29.


Contribution of genes and environment to variation in postural changes in mean arterial and pulse pressure.

Scurrah KJ, Zaloumis SG, Hopper JL, Harrap SB.

J Hypertens. 2008 Dec;26(12):2319-25. doi: 10.1097/HJH.0b013e3283140c89.


Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia.

Ellis JA, Scurrah KJ, Cobb JE, Zaloumis SG, Duncan AE, Harrap SB.

Hum Genet. 2007 May;121(3-4):451-7. Epub 2007 Jan 26.


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