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Items: 27


SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.

Zakrzewicz A, Richter K, Zakrzewicz D, Siebers K, Damm J, Agné A, Hecker A, McIntosh JM, Chamulitrat W, Krasteva-Christ G, Manzini I, Tikkanen R, Padberg W, Janciauskiene S, Grau V.

Front Immunol. 2019 Apr 4;10:664. doi: 10.3389/fimmu.2019.00664. eCollection 2019.


Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells.

Zakrzewicz D, Didiasova M, Krüger M, Giaimo BD, Borggrefe T, Mieth M, Hocke AC, Zakrzewicz A, Schaefer L, Preissner KT, Wygrecka M.

Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1816-1827. doi: 10.1016/j.bbadis.2018.02.021. Epub 2018 Mar 2.


Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells.

Amati AL, Zakrzewicz A, Siebers R, Wilker S, Heldmann S, Zakrzewicz D, Hecker A, McIntosh JM, Padberg W, Grau V.

Mediators Inflamm. 2017;2017:1434872. doi: 10.1155/2017/1434872. Epub 2017 Jul 5.


Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.

Didiasova M, Singh R, Wilhelm J, Kwapiszewska G, Wujak L, Zakrzewicz D, Schaefer L, Markart P, Seeger W, Lauth M, Wygrecka M.

FASEB J. 2017 May;31(5):1916-1928. doi: 10.1096/fj.201600892RR. Epub 2017 Feb 1.


Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury.

Wygrecka M, Kosanovic D, Wujak L, Reppe K, Henneke I, Frey H, Didiasova M, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Zakrzewicz D, Müller-Redetzky HC, de Maat S, Maas C, Nolte MW, Panousis C, Schermuly RT, Seeger W, Witzenrath M, Schaefer L, Markart P.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):186-199. doi: 10.1164/rccm.201604-0712OC.


Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells.

Zakrzewicz D, Bergmann S, Didiasova M, Giaimo BD, Borggrefe T, Mieth M, Hocke AC, Lochnit G, Schaefer L, Hammerschmidt S, Preissner KT, Wygrecka M.

Sci Rep. 2016 Nov 28;6:37758. doi: 10.1038/srep37758.


Elevated protein arginine methyltransferase 1 expression regulates fibroblast motility in pulmonary fibrosis.

Zakrzewicz D, Zakrzewicz A, Didiasova M, Korencak M, Kosanovic D, Schermuly RT, Markart P, Wygrecka M.

Biochim Biophys Acta. 2015 Dec;1852(12):2678-88. doi: 10.1016/j.bbadis.2015.09.008. Epub 2015 Sep 21.


STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.

Didiasova M, Zakrzewicz D, Magdolen V, Nagaraj C, Bálint Z, Rohde M, Preissner KT, Wygrecka M.

J Biol Chem. 2015 May 8;290(19):11983-99. doi: 10.1074/jbc.M114.598425. Epub 2015 Mar 24.


Attenuation of acute rat renal allograft rejection by apolipoprotein E-mimetic Peptide.

Zakrzewicz A, Kutlimuratov K, Atanasova S, Zakrzewicz D, Reichert M, Schmitz J, Wilhelm J, Lochnit G, Padberg W, Grau V.

Transplantation. 2015 May;99(5):925-34. doi: 10.1097/TP.0000000000000569.


Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface.

Wujak L, Didiasova M, Zakrzewicz D, Frey H, Schaefer L, Wygrecka M.

J Biol Chem. 2015 Mar 13;290(11):7027-39. doi: 10.1074/jbc.M114.606343. Epub 2015 Jan 14.


From plasminogen to plasmin: role of plasminogen receptors in human cancer.

Didiasova M, Wujak L, Wygrecka M, Zakrzewicz D.

Int J Mol Sci. 2014 Nov 17;15(11):21229-52. doi: 10.3390/ijms151121229. Review.


Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

Veith C, Zakrzewicz D, Dahal BK, Bálint Z, Murmann K, Wygrecka M, Seeger W, Schermuly RT, Weissmann N, Kwapiszewska G.

Thromb Haemost. 2014 Dec;112(6):1288-303. doi: 10.1160/TH13-12-1031. Epub 2014 Sep 18.


The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization.

Zakrzewicz D, Didiasova M, Zakrzewicz A, Hocke AC, Uhle F, Markart P, Preissner KT, Wygrecka M.

Biochem J. 2014 Jun 1;460(2):295-307. doi: 10.1042/BJ20130945.


Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.

Wygrecka M, Didiasova M, Berscheid S, Piskulak K, Taborski B, Zakrzewicz D, Kwapiszewska G, Preissner KT, Markart P.

Thromb Haemost. 2013 Aug;110(2):295-307. doi: 10.1160/TH12-11-0854. Epub 2013 Jun 6.


Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathway.

Wygrecka M, Dahal BK, Kosanovic D, Petersen F, Taborski B, von Gerlach S, Didiasova M, Zakrzewicz D, Preissner KT, Schermuly RT, Markart P.

Am J Pathol. 2013 Jun;182(6):2094-108. doi: 10.1016/j.ajpath.2013.02.013. Epub 2013 Apr 4.


Protein Arginine Methyltransferases (PRMTs): promising targets for the treatment of pulmonary disorders.

Zakrzewicz D, Zakrzewicz A, Preissner KT, Markart P, Wygrecka M.

Int J Mol Sci. 2012 Sep 27;13(10):12383-400. doi: 10.3390/ijms131012383. Review.


TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner.

Wygrecka M, Zakrzewicz D, Taborski B, Didiasova M, Kwapiszewska G, Preissner KT, Markart P.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):614-27. doi: 10.1165/rcmb.2012-0097OC. Epub 2012 Jul 5.


The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.

Pullamsetti SS, Savai R, Dumitrascu R, Dahal BK, Wilhelm J, Konigshoff M, Zakrzewicz D, Ghofrani HA, Weissmann N, Eickelberg O, Guenther A, Leiper J, Seeger W, Grimminger F, Schermuly RT.

Sci Transl Med. 2011 Jun 15;3(87):87ra53. doi: 10.1126/scitranslmed.3001725.


Shedding of low-density lipoprotein receptor–related protein-1 in acute respiratory distress syndrome.

Wygrecka M, Wilhelm J, Jablonska E, Zakrzewicz D, Preissner KT, Seeger W, Guenther A, Markart P.

Am J Respir Crit Care Med. 2011 Aug 15;184(4):438-48. doi: 10.1164/rccm.201009-1422OC.


Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis.

Wygrecka M, Kwapiszewska G, Jablonska E, von Gerlach S, Henneke I, Zakrzewicz D, Guenther A, Preissner KT, Markart P.

Am J Respir Crit Care Med. 2011 Jun 15;183(12):1703-14. doi: 10.1164/rccm.201009-1479OC. Epub 2011 Mar 11.


Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.

Zakrzewicz D, Zakrzewicz A, Wilker S, Boedeker RH, Padberg W, Eickelberg O, Grau V.

Nephrol Dial Transplant. 2011 Jan;26(1):124-35. doi: 10.1093/ndt/gfq392. Epub 2010 Jul 19.


Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.

Jablonska E, Markart P, Zakrzewicz D, Preissner KT, Wygrecka M.

J Biol Chem. 2010 Apr 9;285(15):11638-51. doi: 10.1074/jbc.M109.045963. Epub 2010 Feb 8.


From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.

Zakrzewicz D, Eickelberg O.

BMC Pulm Med. 2009 Jan 29;9:5. doi: 10.1186/1471-2466-9-5. Review.


Functional role and species-specific contribution of arginases in pulmonary fibrosis.

Kitowska K, Zakrzewicz D, Königshoff M, Chrobak I, Grimminger F, Seeger W, Bulau P, Eickelberg O.

Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L34-45. Epub 2007 Oct 12.


Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA.

Bulau P, Zakrzewicz D, Kitowska K, Leiper J, Gunther A, Grimminger F, Eickelberg O.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L18-24. Epub 2006 Aug 4.


Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases.

Yildirim AO, Bulau P, Zakrzewicz D, Kitowska KE, Weissmann N, Grimminger F, Morty RE, Eickelberg O.

Am J Respir Cell Mol Biol. 2006 Oct;35(4):436-43. Epub 2006 May 11.


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