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Items: 27

1.

Vitamin D prevents lipid accumulation in murine muscle through regulation of PPARγ and perilipin-2 expression.

Li J, Mihalcioiu M, Li L, Zakikhani M, Camirand A, Kremer R.

J Steroid Biochem Mol Biol. 2018 Mar;177:116-124. doi: 10.1016/j.jsbmb.2017.10.010. Epub 2017 Oct 14.

PMID:
29037825
2.

A phenotype of IGFBP-3 knockout mice revealed by dextran sulfate-induced colitis.

Yancu D, Blouin MJ, Birman E, Florianova L, Aleynikova O, Zakikhani M, VanderMeulen H, Seidman E, Pollak M.

J Gastroenterol Hepatol. 2017 Jan;32(1):146-153. doi: 10.1111/jgh.13461.

PMID:
27253188
3.

Germ line knockout of IGFBP-3 reveals influences of the gene on mammary gland neoplasia.

Blouin MJ, Bazile M, Birman E, Zakikhani M, Florianova L, Aleynikova O, Powell DR, Pollak M.

Breast Cancer Res Treat. 2015 Feb;149(3):577-85. doi: 10.1007/s10549-015-3268-8. Epub 2015 Jan 23.

PMID:
25614235
4.

Serine deprivation enhances antineoplastic activity of biguanides.

Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M.

Cancer Res. 2014 Dec 15;74(24):7521-33. doi: 10.1158/0008-5472.CAN-14-2643-T. Epub 2014 Nov 6.

5.

Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin.

Zakikhani M, Bazile M, Hashemi S, Javeshghani S, Avizonis D, St Pierre J, Pollak MN.

PLoS One. 2012;7(11):e49513. doi: 10.1371/journal.pone.0049513. Epub 2012 Nov 21.

6.

Carbon source and myc expression influence the antiproliferative actions of metformin.

Javeshghani S, Zakikhani M, Austin S, Bazile M, Blouin MJ, Topisirovic I, St-Pierre J, Pollak MN.

Cancer Res. 2012 Dec 1;72(23):6257-67. doi: 10.1158/0008-5472.CAN-12-2907. Epub 2012 Oct 4.

7.

The Chemical and Physical Properties of Poly(ε-caprolactone) Scaffolds Functionalised with Poly(vinyl phosphonic acid-co-acrylic acid).

Bassi AK, Gough JE, Zakikhani M, Downes S.

J Tissue Eng. 2011;2011:615328. doi: 10.4061/2011/615328. Epub 2011 Sep 22.

8.

IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer.

Dool CJ, Mashhedi H, Zakikhani M, David S, Zhao Y, Birman E, Carboni JM, Gottardis M, Blouin MJ, Pollak M.

Endocr Relat Cancer. 2011 Nov 14;18(6):699-709. doi: 10.1530/ERC-11-0136. Print 2011 Dec.

PMID:
21946410
9.

Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet.

Mashhedi H, Blouin MJ, Zakikhani M, David S, Zhao Y, Bazile M, Birman E, Algire C, Aliaga A, Bedell BJ, Pollak M.

Cell Cycle. 2011 Aug 15;10(16):2770-8. Epub 2011 Aug 15.

PMID:
21811094
10.

Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.

Algire C, Amrein L, Bazile M, David S, Zakikhani M, Pollak M.

Oncogene. 2011 Mar 10;30(10):1174-82. doi: 10.1038/onc.2010.483. Epub 2010 Nov 22.

PMID:
21102522
11.

Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man.

Inoue T, Zakikhani M, David S, Algire C, Blouin MJ, Pollak M.

Prostate. 2010 Nov 1;70(15):1628-35. doi: 10.1002/pros.21198.

PMID:
20564323
12.

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.

Algire C, Amrein L, Zakikhani M, Panasci L, Pollak M.

Endocr Relat Cancer. 2010 Jun 1;17(2):351-60. doi: 10.1677/ERC-09-0252. Print 2010 Jun.

PMID:
20228137
13.

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.

Zakikhani M, Blouin MJ, Piura E, Pollak MN.

Breast Cancer Res Treat. 2010 Aug;123(1):271-9. doi: 10.1007/s10549-010-0763-9. Epub 2010 Feb 5.

PMID:
20135346
14.

Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose.

Blouin MJ, Zhao Y, Zakikhani M, Algire C, Piura E, Pollak M.

Cancer Lett. 2010 Mar 28;289(2):246-53. doi: 10.1016/j.canlet.2009.08.021. Epub 2009 Sep 9.

PMID:
19744772
15.

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

Avnet S, Sciacca L, Salerno M, Gancitano G, Cassarino MF, Longhi A, Zakikhani M, Carboni JM, Gottardis M, Giunti A, Pollak M, Vigneri R, Baldini N.

Cancer Res. 2009 Mar 15;69(6):2443-52. doi: 10.1158/0008-5472.CAN-08-2645. Epub 2009 Mar 3.

16.

The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase.

Zakikhani M, Dowling RJ, Sonenberg N, Pollak MN.

Cancer Prev Res (Phila). 2008 Oct;1(5):369-75. doi: 10.1158/1940-6207.CAPR-08-0081. Erratum in: Cancer Prev Res (Phila Pa). 2009 Jan;2(1):95.

17.

Insulin receptor expression by human prostate cancers.

Cox ME, Gleave ME, Zakikhani M, Bell RH, Piura E, Vickers E, Cunningham M, Larsson O, Fazli L, Pollak M.

Prostate. 2009 Jan 1;69(1):33-40. doi: 10.1002/pros.20852.

PMID:
18785179
18.

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth.

Algire C, Zakikhani M, Blouin MJ, Shuai JH, Pollak M.

Endocr Relat Cancer. 2008 Sep;15(3):833-9. doi: 10.1677/ERC-08-0038. Epub 2008 May 9.

PMID:
18469156
19.

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells.

Dowling RJ, Zakikhani M, Fantus IG, Pollak M, Sonenberg N.

Cancer Res. 2007 Nov 15;67(22):10804-12.

20.

Modeling water and sediment contamination of Lake Pontchartrain following pump-out of Hurricane Katrina floodwater.

Dortch MS, Zakikhani M, Kim SC, Steevens JA.

J Environ Manage. 2008 May;87(3):429-42. Epub 2007 Mar 30.

PMID:
17399885
21.

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.

Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M.

Cancer Res. 2006 Nov 1;66(21):10269-73. Epub 2006 Oct 23.

22.
23.

A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans.

Putrenko I, Zakikhani M, Dent JA.

J Biol Chem. 2005 Feb 25;280(8):6392-8. Epub 2004 Dec 3.

26.

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