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Items: 1 to 50 of 129

1.

Development of "Quick-DB forensic": A total workflow from QuEChERS-dSPE method to GC-MS/MS quantification of forensically relevant drugs and pesticides in whole blood.

Kusano M, Sakamoto Y, Natori Y, Miyagawa H, Tsuchihashi H, Ishii A, Zaitsu K.

Forensic Sci Int. 2019 Jul;300:125-135. doi: 10.1016/j.forsciint.2019.03.048. Epub 2019 Apr 6.

PMID:
31103910
2.

Corrigendum to "Intact metabolite profiling of mouse brain by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its potential use for local distribution analysis of the brain" [ACA 983 (2017) 160-165].

Hayashi Y, Zaitsu K, Murata T, Ohara T, Moreau S, Kusano M, Tanihata H, Tsuchihashi H, Ishii A, Ishikawa T.

Anal Chim Acta. 2018 Nov 15;1031:196. doi: 10.1016/j.aca.2018.08.001. Epub 2018 Aug 5. No abstract available.

PMID:
30119740
3.

Metabolome analysis of the serotonin syndrome rat model: Abnormal muscular contraction is related to metabolic alterations and hyper-thermogenesis.

Zaitsu K, Noda S, Iguchi A, Hayashi Y, Ohara T, Kimura Y, Koketsu Y, Kosaki T, Kusano M, Sato T, Ishikawa T, Tsuchihashi H, Suzuki K, Ishii A.

Life Sci. 2018 Aug 15;207:550-561. doi: 10.1016/j.lfs.2018.06.031. Epub 2018 Jul 2.

PMID:
30056864
4.

Metabolism of α-PHP and α-PHPP in humans and the effects of alkyl chain lengths on the metabolism of α-pyrrolidinophenone-type designer drugs.

Matsuta S, Shima N, Kakehashi H, Kamata H, Nakano S, Sasaki K, Kamata T, Nishioka H, Miki A, Zaitsu K, Tsuchihashi H, Katagi M.

Forensic Toxicol. 2018;36(2):486-497. doi: 10.1007/s11419-018-0428-7. Epub 2018 May 28.

5.

In Vivo Real-Time Monitoring System Using Probe Electrospray Ionization/Tandem Mass Spectrometry for Metabolites in Mouse Brain.

Zaitsu K, Hayashi Y, Murata T, Yokota K, Ohara T, Kusano M, Tsuchihashi H, Ishikawa T, Ishii A, Ogata K, Tanihata H.

Anal Chem. 2018 Apr 3;90(7):4695-4701. doi: 10.1021/acs.analchem.7b05291. Epub 2018 Mar 19.

PMID:
29519127
6.

High-throughput determination of valproate in human samples by modified QuEChERS extraction and GC-MS/MS.

Mizuno S, Lee XP, Fujishiro M, Matsuyama T, Yamada M, Sakamoto Y, Kusano M, Zaitsu K, Hasegawa C, Hasegawa I, Kumazawa T, Ishii A, Sato K.

Leg Med (Tokyo). 2018 Mar;31:66-73. doi: 10.1016/j.legalmed.2018.01.002. Epub 2018 Feb 3.

PMID:
29413992
7.

Intact metabolite profiling of mouse brain by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its potential use for local distribution analysis of the brain.

Hayashi Y, Zaitsu K, Murata T, Ohara T, Moreau S, Kusano M, Tanihata H, Tsuchihashi H, Ishii A, Ishikawa T.

Anal Chim Acta. 2017 Aug 29;983:160-165. doi: 10.1016/j.aca.2017.06.047. Epub 2017 Jun 30. Erratum in: Anal Chim Acta. 2018 Nov 15;1031:196.

PMID:
28811022
8.

Fatal intoxication by 5F-ADB and diphenidine: Detection, quantification, and investigation of their main metabolic pathways in humans by LC/MS/MS and LC/Q-TOFMS.

Kusano M, Zaitsu K, Taki K, Hisatsune K, Nakajima J, Moriyasu T, Asano T, Hayashi Y, Tsuchihashi H, Ishii A.

Drug Test Anal. 2018 Feb;10(2):284-293. doi: 10.1002/dta.2215. Epub 2017 Jul 19.

PMID:
28544560
9.

Simultaneous quantification of batrachotoxin and epibatidine in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.

Shiraishi Y, Ogawa T, Suzuki T, Iwai M, Kusano M, Zaitsu K, Kondo F, Ishii A, Seno H.

Leg Med (Tokyo). 2017 Mar;25:1-5. doi: 10.1016/j.legalmed.2016.12.008. Epub 2016 Dec 22.

PMID:
28457503
10.

Development of a mass spectrometric hydroxyl-position determination method for the hydroxyindole metabolites of JWH-018 by GC-MS/MS.

Kusano M, Zaitsu K, Yamanaka M, Hisatsune K, Asano T, Taki K, Hayashi Y, Tsuchihashi H, Ishii A.

J Mass Spectrom. 2016 May;51(5):350-7. doi: 10.1002/jms.3761.

PMID:
27194519
11.

Sensitive determination of picrotoxin by liquid chromatography-quadrupole time-of-flight mass spectrometry.

Ogawa T, Tada M, Hattori H, Shiraishi Y, Suzuki T, Iwai M, Kusano M, Zaitsu K, Ishii A, Seno H.

Leg Med (Tokyo). 2016 May;20:8-11. doi: 10.1016/j.legalmed.2016.03.002. Epub 2016 Mar 4. No abstract available.

PMID:
27161913
12.

Intact Endogenous Metabolite Analysis of Mice Liver by Probe Electrospray Ionization/Triple Quadrupole Tandem Mass Spectrometry and Its Preliminary Application to in Vivo Real-Time Analysis.

Zaitsu K, Hayashi Y, Murata T, Ohara T, Nakagiri K, Kusano M, Nakajima H, Nakajima T, Ishikawa T, Tsuchihashi H, Ishii A.

Anal Chem. 2016 Apr 5;88(7):3556-61. doi: 10.1021/acs.analchem.5b04046. Epub 2016 Mar 9.

PMID:
26958983
13.

Erratum to: High-resolution mass spectrometric determination of the synthetic cannabinoids MAM-2201, AM-1220, AM-2232, and their metabolites in postmortem plasma and urine by LC/Q-TOFMS.

Zaitsu K, Nakayama H, Yamanaka M, Hisatsune K, Taki K, Asano T, Kamata T, Katagi M, Hayashi Y, Kusano M, Tsuchihashi H, Ishii A.

Int J Legal Med. 2016 Jan;130(1):309-16. doi: 10.1007/s00414-015-1294-z. No abstract available.

PMID:
26718839
14.

Application of metabolomics to toxicology of drugs of abuse: A mini review of metabolomics approach to acute and chronic toxicity studies.

Zaitsu K, Hayashi Y, Kusano M, Tsuchihashi H, Ishii A.

Drug Metab Pharmacokinet. 2016 Feb;31(1):21-26. doi: 10.1016/j.dmpk.2015.10.002. Epub 2015 Nov 2. Review.

PMID:
26613805
15.

Development of a Fully-automated On-line Oxidation Column-switching HPLC System for the Determination of Endogenous Melatonin in Human Clinical Samples.

Oyama T, Nagai R, Fujimoto M, Konishi R, Mita M, Uezono K, Zaitsu K, Hamase K.

Anal Sci. 2015;31(11):1129-35. doi: 10.2116/analsci.31.1129.

16.

High-resolution mass spectrometric determination of the synthetic cannabinoids MAM-2201, AM-2201, AM-2232, and their metabolites in postmortem plasma and urine by LC/Q-TOFMS.

Zaitsu K, Nakayama H, Yamanaka M, Hisatsune K, Taki K, Asano T, Kamata T, Katagai M, Hayashi Y, Kusano M, Tsuchihashi H, Ishii A.

Int J Legal Med. 2015 Nov;129(6):1233-45. doi: 10.1007/s00414-015-1257-4. Epub 2015 Sep 8. Erratum in: Int J Legal Med. 2016 Jan;130(1):309-16.

PMID:
26349566
17.

Association Between Extraversion and Exercise Performance Among Elderly Persons Receiving a Videogame Intervention.

Zaitsu K, Nishimura Y, Matsuguma H, Higuchi S.

Games Health J. 2015 Oct;4(5):375-80. doi: 10.1089/g4h.2014.0119. Epub 2015 May 20.

PMID:
26287928
18.

Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201.

Zaitsu K, Hayashi Y, Suzuki K, Nakayama H, Hattori N, Takahara R, Kusano M, Tsuchihashi H, Ishii A.

Life Sci. 2015 Sep 15;137:49-55. doi: 10.1016/j.lfs.2015.05.013. Epub 2015 May 30.

PMID:
26032255
19.

Time-course mass spectrometry imaging for depicting drug incorporation into hair.

Kamata T, Shima N, Sasaki K, Matsuta S, Takei S, Katagi M, Miki A, Zaitsu K, Nakanishi T, Sato T, Suzuki K, Tsuchihashi H.

Anal Chem. 2015 Jun 2;87(11):5476-81. doi: 10.1021/acs.analchem.5b00971. Epub 2015 May 6.

PMID:
25919888
20.

Positional isomer differentiation of synthetic cannabinoid JWH-081 by GC-MS/MS.

Kusano M, Zaitsu K, Nakayama H, Nakajima J, Hisatsune K, Moriyasu T, Matsuta S, Katagi M, Tsuchihashi H, Ishii A.

J Mass Spectrom. 2015 Mar;50(3):586-91. doi: 10.1002/jms.3565.

PMID:
25800195
21.

A preliminary study on postmortem interval estimation of suffocated rats by GC-MS/MS-based plasma metabolic profiling.

Sato T, Zaitsu K, Tsuboi K, Nomura M, Kusano M, Shima N, Abe S, Ishii A, Tsuchihashi H, Suzuki K.

Anal Bioanal Chem. 2015 May;407(13):3659-65. doi: 10.1007/s00216-015-8584-7. Epub 2015 Mar 8.

PMID:
25749795
22.

Metabolism of the designer drug α-pyrrolidinobutiophenone (α-PBP) in humans: identification and quantification of the phase I metabolites in urine.

Matsuta S, Shima N, Kamata H, Kakehashi H, Nakano S, Sasaki K, Kamata T, Nishioka H, Miki A, Katagi M, Zaitsu K, Sato T, Tsuchihashi H, Suzuki K.

Forensic Sci Int. 2015 Apr;249:181-8. doi: 10.1016/j.forsciint.2015.02.004. Epub 2015 Feb 8.

PMID:
25703013
23.
24.

A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model.

Jia X, Suzuki Y, Naito H, Yetti H, Kitamori K, Hayashi Y, Kaneko R, Nomura M, Yamori Y, Zaitsu K, Kato M, Ishii A, Nakajima T.

Dig Dis Sci. 2014 Jul;59(7):1490-501. doi: 10.1007/s10620-014-3028-3. Epub 2014 Jan 22.

PMID:
24448653
25.

Development of a simple one-pot extraction method for various drugs and metabolites of forensic interest in blood by modifying the QuEChERS method.

Matsuta S, Nakanishi K, Miki A, Zaitsu K, Shima N, Kamata T, Nishioka H, Katagi M, Tatsuno M, Tsuboi K, Tsuchihashi H, Suzuki K.

Forensic Sci Int. 2013 Oct 10;232(1-3):40-5. doi: 10.1016/j.forsciint.2013.06.015. Epub 2013 Jul 27.

PMID:
24053863
26.

Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.

Zaitsu K, Miyawaki I, Bando K, Horie H, Shima N, Katagi M, Tatsuno M, Bamba T, Sato T, Ishii A, Tsuchihashi H, Suzuki K, Fukusaki E.

Anal Bioanal Chem. 2014 Feb;406(5):1339-54. doi: 10.1007/s00216-013-7234-1. Epub 2013 Aug 4.

PMID:
23912828
27.

Simultaneous enantiomeric determination of MDMA and its phase I and phase II metabolites in urine by liquid chromatography-tandem mass spectrometry with chiral derivatization.

Nakanishi K, Katagi M, Zaitsu K, Shima N, Kamata H, Miki A, Kato H, Harada K, Tsuchihashi H, Suzuki K.

Anal Bioanal Chem. 2012 Nov;404(8):2427-35. doi: 10.1007/s00216-012-6385-9. Epub 2012 Sep 26.

PMID:
23010844
28.

Cross-reactivities of various phenethylamine-type designer drugs to immunoassays for amphetamines, with special attention to the evaluation of the one-step urine drug test Instant-View™, and the Emit® assays for use in drug enforcement.

Nakanishi K, Miki A, Zaitsu K, Kamata H, Shima N, Kamata T, Katagi M, Tatsuno M, Tsuchihashi H, Suzuki K.

Forensic Sci Int. 2012 Apr 10;217(1-3):174-81. doi: 10.1016/j.forsciint.2011.11.003. Epub 2011 Dec 7.

PMID:
22154438
29.

Influences of methamphetamine-induced acute intoxication on urinary and plasma metabolic profiles in the rat.

Shima N, Miyawaki I, Bando K, Horie H, Zaitsu K, Katagi M, Bamba T, Tsuchihashi H, Fukusaki E.

Toxicology. 2011 Sep 5;287(1-3):29-37. doi: 10.1016/j.tox.2011.05.012. Epub 2011 May 27.

PMID:
21645582
30.

D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor.

Kakegawa W, Miyoshi Y, Hamase K, Matsuda S, Matsuda K, Kohda K, Emi K, Motohashi J, Konno R, Zaitsu K, Yuzaki M.

Nat Neurosci. 2011 May;14(5):603-11. doi: 10.1038/nn.2791. Epub 2011 Apr 3.

PMID:
21460832
31.

MALDI-TOF and MALDI-FTICR imaging mass spectrometry of methamphetamine incorporated into hair.

Miki A, Katagi M, Kamata T, Zaitsu K, Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K.

J Mass Spectrom. 2011 Apr;46(4):411-6. doi: 10.1002/jms.1908.

PMID:
21438091
32.

Simultaneous determination of D-aspartic acid and D-glutamic acid in rat tissues and physiological fluids using a multi-loop two-dimensional HPLC procedure.

Han H, Miyoshi Y, Ueno K, Okamura C, Tojo Y, Mita M, Lindner W, Zaitsu K, Hamase K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Nov 1;879(29):3196-202. doi: 10.1016/j.jchromb.2011.01.023. Epub 2011 Feb 2.

PMID:
21371949
33.

Fluorescence properties of 2-aryl substituted indoles.

Nakazono M, Saita K, Oshikawa Y, Tani K, Nanbu S, Zaitsu K.

Spectrochim Acta A Mol Biomol Spectrosc. 2011 Feb;78(2):905-8. doi: 10.1016/j.saa.2010.11.031. Epub 2010 Dec 4.

PMID:
21177140
34.

Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain.

Yang JH, Wada A, Yoshida K, Miyoshi Y, Sayano T, Esaki K, Kinoshita MO, Tomonaga S, Azuma N, Watanabe M, Hamase K, Zaitsu K, Machida T, Messing A, Itohara S, Hirabayashi Y, Furuya S.

J Biol Chem. 2010 Dec 31;285(53):41380-90. doi: 10.1074/jbc.M110.187443. Epub 2010 Oct 21.

35.

Simultaneous two-dimensional HPLC determination of free D-serine and D-alanine in the brain and periphery of mutant rats lacking D-amino-acid oxidase.

Miyoshi Y, Hamase K, Okamura T, Konno R, Kasai N, Tojo Y, Zaitsu K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Nov 1;879(29):3184-9. doi: 10.1016/j.jchromb.2010.08.024. Epub 2010 Aug 22.

PMID:
20851062
36.

Fluorescence and chemiluminescence properties of indolylmaleimides: experimental and theoretical studies.

Nakazono M, Jinguji A, Nanbu S, Kuwano R, Zheng Z, Saita K, Oshikawa Y, Mikuni Y, Murakami T, Zhao Y, Sasaki S, Zaitsu K.

Phys Chem Chem Phys. 2010 Sep 7;12(33):9783-93. doi: 10.1039/c003021j. Epub 2010 Jun 22.

PMID:
20571686
37.

Mutant mice and rats lacking D-amino acid oxidase.

Konno R, Hamase K, Maruyama R, Zaitsu K.

Chem Biodivers. 2010 Jun;7(6):1450-8. doi: 10.1002/cbdv.200900303. Review.

PMID:
20564563
38.

Metabolism and toxicologic analysis of tryptamine-derived drugs of abuse.

Katagi M, Kamata T, Zaitsu K, Shima N, Kamata H, Nakanishi K, Nishioka H, Miki A, Tsuchihashi H.

Ther Drug Monit. 2010 Jun;32(3):328-31. doi: 10.1097/FTD.0b013e3181dcb40c.

PMID:
20418800
39.

6,7-Difluoro-1,4-dihydro-1-methyl-4-oxo-3-quinolinecarboxylic acid, a newly designed fluorescence enhancement-type derivatizing reagent for amino compounds.

Hirano J, Hamase K, Miyata H, Zaitsu K.

J Fluoresc. 2010 Mar;20(2):615-24. doi: 10.1007/s10895-009-0596-2. Epub 2010 Jan 28.

PMID:
20108029
40.

Simultaneous determination of hydrophilic amino acid enantiomers in mammalian tissues and physiological fluids applying a fully automated micro-two-dimensional high-performance liquid chromatographic concept.

Hamase K, Miyoshi Y, Ueno K, Han H, Hirano J, Morikawa A, Mita M, Kaneko T, Lindner W, Zaitsu K.

J Chromatogr A. 2010 Feb 12;1217(7):1056-62. doi: 10.1016/j.chroma.2009.09.002. Epub 2009 Sep 6.

PMID:
19767006
41.

Analysis of small amounts of D-amino acids and the study of their physiological functions in mammals.

Hamase K, Morikawa A, Etoh S, Tojo Y, Miyoshi Y, Zaitsu K.

Anal Sci. 2009 Aug;25(8):961-8. Review.

42.

Chemiluminescence enhancement of 1,2-di[3,4,5-tri(3,4,5-trihydroxybenzoyloxy)benzoyloxy] benzene in the presence of quaternary ammonium ions.

Nakazono M, Agawa H, Nanbu S, Zaitsu K.

Luminescence. 2010 Sep-Oct;25(5):360-3. doi: 10.1002/bio.1156.

PMID:
19630093
43.

Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection.

Miyoshi Y, Hamase K, Tojo Y, Mita M, Konno R, Zaitsu K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Aug 15;877(24):2506-12. doi: 10.1016/j.jchromb.2009.06.028. Epub 2009 Jun 23.

PMID:
19586804
44.

Theoretical study of photophysical properties of bisindolylmaleimide derivatives.

Saita K, Nakazono M, Zaitsu K, Nanbu S, Sekiya H.

J Phys Chem A. 2009 Jul 23;113(29):8213-20. doi: 10.1021/jp9043489.

PMID:
19569696
45.

Determination of the metabolites of the new designer drugs bk-MBDB and bk-MDEA in human urine.

Zaitsu K, Katagi M, Kamata HT, Kamata T, Shima N, Miki A, Tsuchihashi H, Mori Y.

Forensic Sci Int. 2009 Jul 1;188(1-3):131-9. doi: 10.1016/j.forsciint.2009.04.001. Epub 2009 Apr 29.

PMID:
19406592
46.

Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis.

Tojo Y, Hamase K, Konno R, Koyanagi S, Ohdo S, Zaitsu K.

J Sep Sci. 2009 Feb;32(3):430-6. doi: 10.1002/jssc.200800587.

PMID:
19142914
47.

The chemiluminescence mechanism of 3,4-bis(3-indolyl)-1H-pyrrole-2,5-dione, and the characteristics of chemiluminescence developed in the reaction with CH(3)CNH(2)O(2)NaOH.

Nakazono M, Uesaki A, Zaitsu K.

Talanta. 2006 Aug 15;70(1):128-32. doi: 10.1016/j.talanta.2005.12.021. Epub 2006 Jan 18.

PMID:
18970740
48.

Chemiluminescence change of polyphenol dendrimers with different core molecules.

Agawa H, Nakazono M, Nanbu S, Zaitsu K.

Org Lett. 2008 Nov 20;10(22):5171-4. doi: 10.1021/ol802129a. Epub 2008 Oct 28.

PMID:
18954060
49.

Enantioselective visualization of D-alanine in rat anterior pituitary gland: localization to ACTH-secreting cells.

Etoh S, Hamase K, Morikawa A, Ohgusu T, Zaitsu K.

Anal Bioanal Chem. 2009 Jan;393(1):217-23. doi: 10.1007/s00216-008-2401-5. Epub 2008 Oct 4.

PMID:
18839155
50.

Automated and simultaneous two-dimensional micro-high-performance liquid chromatographic determination of proline and hydroxyproline enantiomers in mammals.

Tojo Y, Hamase K, Nakata M, Morikawa A, Mita M, Ashida Y, Lindner W, Zaitsu K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):174-9. doi: 10.1016/j.jchromb.2008.06.025.

PMID:
18619929

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