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Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes.

Zaidi SK, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Mol Cancer Res. 2018 Nov;16(11):1617-1624. doi: 10.1158/1541-7786.MCR-18-0415. Epub 2018 Jul 12. Review.


Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity.

Hong D, Fritz AJ, Zaidi SK, van Wijnen AJ, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Dec;233(12):9136-9144. doi: 10.1002/jcp.26847. Epub 2018 Jul 3. Review.


Nuclear organization mediates cancer-compromised genetic and epigenetic control.

Zaidi SK, Fritz AJ, Tracy KM, Gordon JA, Tye CE, Boyd J, Van Wijnen AJ, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Adv Biol Regul. 2018 Aug;69:1-10. doi: 10.1016/j.jbior.2018.05.001. Epub 2018 May 9. Review.


Molecular and enzoinformatics perspectives of targeting Polo-like kinase 1 in cancer therapy.

Shakil S, Baig MH, Tabrez S, Rizvi SMD, Zaidi SK, Ashraf GM, Ansari SA, Khan AAP, Al-Qahtani MH, Abuzenadah AM, Chaudhary AG.

Semin Cancer Biol. 2017 Nov 6. pii: S1044-579X(17)30132-3. doi: 10.1016/j.semcancer.2017.11.004. [Epub ahead of print] Review.


Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer.

Zaidi SK, Frietze SE, Gordon JA, Heath JL, Messier T, Hong D, Boyd JR, Kang M, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00352-17. doi: 10.1128/MCB.00352-17. Print 2017 Dec 1. Review.


Amoxycillin and clavulanic acid induced Stevens-Johnson syndrome: A case report.

Zaidi M, Zaidi SK, Bhutto M, Umer MY.

EXCLI J. 2017 May 18;16:748-751. doi: 10.17179/excli2017-345. eCollection 2017.


An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells.

Zaidi SK, Perez AW, White ES, Lian JB, Stein JL, Stein GS.

Oncotarget. 2017 Jun 20;8(25):39994-40005. doi: 10.18632/oncotarget.18127.


Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

Fritz AJ, Ghule PN, Boyd JR, Tye CE, Page NA, Hong D, Shirley DJ, Weinheimer AS, Barutcu AR, Gerrard DL, Frietze S, van Wijnen AJ, Zaidi SK, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Feb;233(2):1278-1290. doi: 10.1002/jcp.25996. Epub 2017 Jun 22.


X-linked agammaglobulinemia - first case with Bruton tyrosine kinase mutation from Pakistan.

Zaidi SK, Qureshi S, Qamar FN.

J Pak Med Assoc. 2017 Mar;67(3):471-473.


Mitotic Gene Bookmarking: An Epigenetic Mechanism for Coordination of Lineage Commitment, Cell Identity and Cell Growth.

Zaidi SK, Lian JB, van Wijnen A, Stein JL, Stein GS.

Adv Exp Med Biol. 2017;962:95-102. doi: 10.1007/978-981-10-3233-2_7. Review.


Estimation of Interleukin-1β Promoter (-31 C/T and -511 T/C) Polymorphisms and Its Level in Coronary Artery Disease Patients.

Tabrez S, Jabir NR, Firoz CK, Hindawi S, Shakil S, Damanhouri GA, Zaidi SK.

J Cell Biochem. 2017 Sep;118(9):2977-2982. doi: 10.1002/jcb.25958. Epub 2017 Apr 12.


Garlic extract attenuates immobilization stress-induced alterations in plasma antioxidant/oxidant parameters and hepatic function in rats.

Zaidi SK, Ansari SA, Tabrez S, Hoda MN, Ashraf GM, Khan MS, Alnohair S, Banu N, Al-Qahtani MH.

Chin J Integr Med. 2017 Feb 15. doi: 10.1007/s11655-016-2644-5. [Epub ahead of print]


Exploration of Various Proteins for the Treatment of Alzheimer's Disease.

Islam BU, Zaidi SK, Kamal MA, Tabrez S.

Curr Drug Metab. 2017;18(9):808-813. doi: 10.2174/1389200218666170203110135. Review.


Galectins-A Potential Target for Cardiovascular Therapy.

Ashraf GM, Perveen A, Zaidi SK, Ahmad A, Shakil S, Firoz CK, Jabir NR, Hassan I, Khan TA, Yarla NS, Tabrez S.

Curr Vasc Pharmacol. 2017;15(4):296-312. doi: 10.2174/1570161115666170201113046. Review.


Common Therapeutic Modalities Against Diabetes and Associated Cardiovascular Disease.

Jabir NR, Firoz CK, Ashraf GM, Zaidi SK, Shakil S, Kamal MA, Tabrez S.

Curr Vasc Pharmacol. 2017;15(4):365-373. doi: 10.2174/1570161115666170105125034. Review.


Copy number variations in Saudi family with intellectual disability and epilepsy.

Naseer MI, Chaudhary AG, Rasool M, Kalamegam G, Ashgan FT, Assidi M, Ahmed F, Ansari SA, Zaidi SK, Jan MM, Al-Qahtani MH.

BMC Genomics. 2016 Oct 17;17(Suppl 9):757.


Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

Stem Cell Reports. 2016 Nov 8;7(5):884-896. doi: 10.1016/j.stemcr.2016.09.006. Epub 2016 Oct 6.


Precocious Phenotypic Transcription-Factor Expression During Early Development.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Biochem. 2017 May;118(5):953-958. doi: 10.1002/jcb.25723. Epub 2017 Jan 11. Review.


Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.

VanOudenhove JJ, Grandy RA, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Physiol. 2017 Jun;232(6):1254-1257. doi: 10.1002/jcp.25567. Epub 2017 Jan 31. Review.


Potential Linkage Between Cerebrovascular Diseases and Metabolic Syndrome.

Jabir NR, Firoz CK, Khan MS, Zaidi SK, Ashraf GM, Shakil S, Kamal MA, Tabrez S.

Curr Drug Metab. 2017;18(1):62-68. doi: 10.2174/1389200217666160810155055. Review.


Thyroid Hormone Receptor-β (TRβ) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer.

Carr FE, Tai PW, Barnum MS, Gillis NE, Evans KG, Taber TH, White JH, Tomczak JA, Jaworski DM, Zaidi SK, Lian JB, Stein JL, Stein GS.

Endocrinology. 2016 Aug;157(8):3278-92. doi: 10.1210/en.2015-2046. Epub 2016 Jun 2.


Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy.

Ahmad S, ElSherbiny NM, Jamal MS, Alzahrani FA, Haque R, Khan R, Zaidi SK, AlQahtani MH, Liou GI, Bhatia K.

J Neuroimmunol. 2016 Jun 15;295-296:47-53. doi: 10.1016/j.jneuroim.2016.04.002. Epub 2016 Apr 12.


Lineage-Specific Early Differentiation of Human Embryonic Stem Cells Requires a G2 Cell Cycle Pause.

Van Oudenhove JJ, Grandy RA, Ghule PN, Del Rio R, Lian JB, Stein JL, Zaidi SK, Stein GS.

Stem Cells. 2016 Jul;34(7):1765-75. doi: 10.1002/stem.2352. Epub 2016 Mar 28. Erratum in: Stem Cells. 2016 Oct;34(10 ):2612.


Linkage of Stress with Neuromuscular Disorders.

Ashraf GM, Ali A, Tabrez S, Zaidi SK, Shakil S, Alam MZ, Rehan M, Aliev G.

CNS Neurol Disord Drug Targets. 2016;15(3):321-8. Review.


Expression of Ribosomal RNA and Protein Genes in Human Embryonic Stem Cells Is Associated With the Activating H3K4me3 Histone Mark.

Zaidi SK, Boyd JR, Grandy RA, Medina R, Lian JB, Stein GS, Stein JL.

J Cell Physiol. 2016 Sep;231(9):2007-13. doi: 10.1002/jcp.25309. Epub 2016 Feb 5.


MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells.

Browne G, Dragon JA, Hong D, Messier TL, Gordon JA, Farina NH, Boyd JR, VanOudenhove JJ, Perez AW, Zaidi SK, Stein JL, Stein GS, Lian JB.

Tumour Biol. 2016 Jul;37(7):8825-39. doi: 10.1007/s13277-015-4710-6. Epub 2016 Jan 9.


Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation.

Grandy RA, Whitfield TW, Wu H, Fitzgerald MP, VanOudenhove JJ, Zaidi SK, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS.

Mol Cell Biol. 2015 Dec 7;36(4):615-27. doi: 10.1128/MCB.00877-15. Print 2016 Feb 15.


Current Updates on Therapeutic Advances in the Management of Cardiovascular Diseases.

Jabir NR, Siddiqui AN, Firoz CK, Ashraf GM, Zaidi SK, Khan MS, Shakil S, Alama MN, Kamal MA, Tabrez S.

Curr Pharm Des. 2016;22(5):566-71. Review.


Chronic unpredictable stress deteriorates the chemopreventive efficacy of pomegranate through oxidative stress pathway.

Hasan S, Suhail N, Bilal N, Ashraf GM, Zaidi SK, AlNohair S, Banu N.

Tumour Biol. 2016 May;37(5):5999-6006. doi: 10.1007/s13277-015-4469-9. Epub 2015 Nov 23.


Recent Updates on the Association Between Alzheimer's Disease and Vascular Dementia.

Ashraf GM, Chibber S, Mohammad, Zaidi SK, Tabrez S, Ahmad A, Shakil S, Mushtaq G, Baeesa SS, Kamal MA.

Med Chem. 2016;12(3):226-37. Review.


Integrating Qualitative and Quantitative Tools for the Detection and Identification of Lectins in Major Human Diseases.

Ashraf GM, Perveen A, Zaidi SK, Tabrez S, Shakil S, Ahmad A, Haque R, Ahsan J, Kamal MA, Banu N.

Protein Pept Lett. 2015;22(11):954-62. Review.


Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus.

Fritz AJ, Barutcu AR, Martin-Buley L, van Wijnen AJ, Zaidi SK, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Biochem. 2016 Jan;117(1):9-19. doi: 10.1002/jcb.25280.


MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer.

Jafri MA, Zaidi SK, Ansari SA, Al-Qahtani MH, Shay JW.

Expert Opin Ther Targets. 2015;19(12):1705-23. doi: 10.1517/14728222.2015.1069816. Epub 2015 Jul 18. Review.


C-ing the Genome: A Compendium of Chromosome Conformation Capture Methods to Study Higher-Order Chromatin Organization.

Barutcu AR, Fritz AJ, Zaidi SK, van Wijnen AJ, Lian JB, Stein JL, Nickerson JA, Imbalzano AN, Stein GS.

J Cell Physiol. 2016 Jan;231(1):31-5. doi: 10.1002/jcp.25062. Review.


Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells.

Trombly DJ, Whitfield TW, Padmanabhan S, Gordon JA, Lian JB, van Wijnen AJ, Zaidi SK, Stein JL, Stein GS.

BMC Genomics. 2015 Apr 17;16:309. doi: 10.1186/s12864-015-1445-0.


Studies on the role of goat heart galectin-1 as an erythrocyte membrane perturbing agent.

Ashraf GM, Perveen A, Zaidi SK, Tabrez S, Kamal MA, Banu N.

Saudi J Biol Sci. 2015 Jan;22(1):112-6. doi: 10.1016/j.sjbs.2014.09.018. Epub 2014 Oct 5.


Studies on the role of goat heart galectin-1 as a tool for detecting post-malignant changes in glycosylation pattern.

Ashraf GM, Perveen A, Tabrez S, Zaidi SK, Kamal MA, Banu N.

Saudi J Biol Sci. 2015 Jan;22(1):85-9. doi: 10.1016/j.sjbs.2014.07.008. Epub 2014 Aug 12.


An overview on the correlation of neurological disorders with cardiovascular disease.

Firoz CK, Jabir NR, Khan MS, Mahmoud M, Shakil S, Damanhouri GA, Zaidi SK, Tabrez S, Kamal MA.

Saudi J Biol Sci. 2015 Jan;22(1):19-23. doi: 10.1016/j.sjbs.2014.09.003. Epub 2014 Sep 6. Review.


A Synopsis of Nano-Technological Approaches Toward Anti-Epilepsy Therapy: Present and Future Research Implications.

Jabir NR, Tabrez S, Firoz CK, Zaidi SK, Baeesa SS, Gan SH, Shakil S, Kamal MA.

Curr Drug Metab. 2015;16(5):336-45. Review.


Altered galectin glycosylation: potential factor for the diagnostics and therapeutics of various cardiovascular and neurological disorders.

Ashraf GM, Perveen A, Tabrez S, Jabir NR, Damanhouri GA, Zaidi SK, Banu N.

Adv Exp Med Biol. 2015;822:67-84. doi: 10.1007/978-3-319-08927-0_10.


Correlation of Toll-like receptor 4, interleukin-18, transaminases, and uric acid in patients with chronic periodontitis and healthy adults.

Banu S, Jabir NR, Mohan R, Manjunath NC, Kamal MA, Kumar KR, Zaidi SK, Khan MS, Tabrez S.

J Periodontol. 2015 Mar;86(3):431-9. doi: 10.1902/jop.2014.140414. Epub 2014 Oct 27.


Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus.

Ashraf GM, Greig NH, Khan TA, Hassan I, Tabrez S, Shakil S, Sheikh IA, Zaidi SK, Akram M, Jabir NR, Firoz CK, Naeem A, Alhazza IM, Damanhouri GA, Kamal MA.

CNS Neurol Disord Drug Targets. 2014;13(7):1280-93.


Epigenetic landscape of acute myelogenous leukemia--moving toward personalized medicine.

Lamba G, Zaidi SK, Luebbers K, Verschraegen C, Stein GS, Rosmarin A.

J Cell Biochem. 2014 Oct;115(10):1669-72. doi: 10.1002/jcb.24853.


p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene.

Zaidi SK, Shen WJ, Bittner S, Bittner A, McLean MP, Han J, Davis RJ, Kraemer FB, Azhar S.

J Mol Endocrinol. 2014 Aug;53(1):1-16. doi: 10.1530/JME-13-0287. Epub 2014 Apr 29.


Protective Effect of Solanum nigrum Leaves Extract on Immobilization Stress Induced Changes in Rat's Brain.

Zaidi SK, Hoda MN, Tabrez S, Ansari SA, Jafri MA, Shahnawaz Khan M, Hasan S, Alqahtani MH, Mohammed Abuzenadah A, Banu N.

Evid Based Complement Alternat Med. 2014;2014:912450. doi: 10.1155/2014/912450. Epub 2014 Feb 9.


Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

Zaidi SK, Grandy RA, Lopez-Camacho C, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS.

Cancer Res. 2014 Jan 15;74(2):420-5. doi: 10.1158/0008-5472.CAN-13-2837. Epub 2014 Jan 9. Review.


Remote ischemic perconditioning is effective after embolic stroke in ovariectomized female mice.

Hoda MN, Bhatia K, Hafez SS, Johnson MH, Siddiqui S, Ergul A, Zaidi SK, Fagan SC, Hess DC.

Transl Stroke Res. 2014 Aug;5(4):484-90. doi: 10.1007/s12975-013-0318-6. Epub 2014 Jan 4.


Gene-environment interactions in heavy metal and pesticide carcinogenesis.

Tabrez S, Priyadarshini M, Priyamvada S, Khan MS, Na A, Zaidi SK.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Jan 15;760:1-9. doi: 10.1016/j.mrgentox.2013.11.002. Epub 2013 Dec 3. Review.


The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

Tai PW, Zaidi SK, Wu H, Grandy RA, Montecino M, van Wijnen AJ, Lian JB, Stein GS, Stein JL.

J Cell Physiol. 2014 Jun;229(6):711-27. doi: 10.1002/jcp.24508. Review.


A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation.

Dowdy CR, Frederick D, Zaidi SK, Colby JL, Lian JB, van Wijnen AJ, Gerstein RM, Stein JL, Stein GS.

Exp Hematol. 2013 Nov;41(11):980-991.e1. doi: 10.1016/j.exphem.2013.06.006. Epub 2013 Jun 30.

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