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Items: 31


Association of Mycobacterium Proteins with Lipid Droplets.

Armstrong RM, Carter DC, Atkinson SN, Terhune SS, Zahrt TC.

J Bacteriol. 2018 Jul 25;200(16). pii: e00240-18. doi: 10.1128/JB.00240-18. Print 2018 Aug 15.


Rv2744c Is a PspA Ortholog That Regulates Lipid Droplet Homeostasis and Nonreplicating Persistence in Mycobacterium tuberculosis.

Armstrong RM, Adams KL, Zilisch JE, Bretl DJ, Sato H, Anderson DM, Zahrt TC.

J Bacteriol. 2016 May 13;198(11):1645-1661. doi: 10.1128/JB.01001-15. Print 2016 Jun 1.


The MprB extracytoplasmic domain negatively regulates activation of the Mycobacterium tuberculosis MprAB two-component system.

Bretl DJ, Bigley TM, Terhune SS, Zahrt TC.

J Bacteriol. 2014 Jan;196(2):391-406. doi: 10.1128/JB.01064-13. Epub 2013 Nov 1.


Mechanisms of Francisella tularensis intracellular pathogenesis.

Celli J, Zahrt TC.

Cold Spring Harb Perspect Med. 2013 Apr 1;3(4):a010314. doi: 10.1101/cshperspect.a010314. Review.


MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c.

Bretl DJ, He H, Demetriadou C, White MJ, Penoske RM, Salzman NH, Zahrt TC.

Infect Immun. 2012 Sep;80(9):3018-33. doi: 10.1128/IAI.00520-12. Epub 2012 Jun 11.


Adaptation to environmental stimuli within the host: two-component signal transduction systems of Mycobacterium tuberculosis.

Bretl DJ, Demetriadou C, Zahrt TC.

Microbiol Mol Biol Rev. 2011 Dec;75(4):566-82. doi: 10.1128/MMBR.05004-11. Review.


Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis.

He H, Bretl DJ, Penoske RM, Anderson DM, Zahrt TC.

J Bacteriol. 2011 Oct;193(19):5105-18. doi: 10.1128/JB.05562-11. Epub 2011 Aug 5.


The HtrA-like serine protease PepD interacts with and modulates the Mycobacterium tuberculosis 35-kDa antigen outer envelope protein.

White MJ, Savaryn JP, Bretl DJ, He H, Penoske RM, Terhune SS, Zahrt TC.

PLoS One. 2011 Mar 22;6(3):e18175. doi: 10.1371/journal.pone.0018175.


Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

Apicella MA, Post DM, Fowler AC, Jones BD, Rasmussen JA, Hunt JR, Imagawa S, Choudhury B, Inzana TJ, Maier TM, Frank DW, Zahrt TC, Chaloner K, Jennings MP, McLendon MK, Gibson BW.

PLoS One. 2010 Jul 6;5(7):e11060. doi: 10.1371/journal.pone.0011060.


PepD participates in the mycobacterial stress response mediated through MprAB and SigE.

White MJ, He H, Penoske RM, Twining SS, Zahrt TC.

J Bacteriol. 2010 Mar;192(6):1498-510. doi: 10.1128/JB.01167-09. Epub 2010 Jan 8.


Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.

Pechous RD, McCarthy TR, Zahrt TC.

Microbiol Mol Biol Rev. 2009 Dec;73(4):684-711. doi: 10.1128/MMBR.00028-09. Review.


A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge.

Pechous RD, McCarthy TR, Mohapatra NP, Soni S, Penoske RM, Salzman NH, Frank DW, Gunn JS, Zahrt TC.

PLoS One. 2008 Jun 25;3(6):e2487. doi: 10.1371/journal.pone.0002487.


Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages.

Maier TM, Casey MS, Becker RH, Dorsey CW, Glass EM, Maltsev N, Zahrt TC, Frank DW.

Infect Immun. 2007 Nov;75(11):5376-89. Epub 2007 Aug 6.


Genetics and genetic manipulation in Francisella tularensis.

Frank DW, Zahrt TC.

Ann N Y Acad Sci. 2007 Jun;1105:67-97. Epub 2007 Mar 29. Review.


Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain.

Pechous R, Celli J, Penoske R, Hayes SF, Frank DW, Zahrt TC.

Infect Immun. 2006 Aug;74(8):4452-61.


In vivo Himar1-based transposon mutagenesis of Francisella tularensis.

Maier TM, Pechous R, Casey M, Zahrt TC, Frank DW.

Appl Environ Microbiol. 2006 Mar;72(3):1878-85.


Construction and characterization of a highly efficient Francisella shuttle plasmid.

Maier TM, Havig A, Casey M, Nano FE, Frank DW, Zahrt TC.

Appl Environ Microbiol. 2004 Dec;70(12):7511-9.


Utilization of a labeled tracking oligonucleotide for visualization and quality control of spotted 70-mer arrays.

Hessner MJ, Singh VK, Wang X, Khan S, Tschannen MR, Zahrt TC.

BMC Genomics. 2004 Feb 9;5(1):12.


Functional analysis of the Mycobacterium tuberculosis MprAB two-component signal transduction system.

Zahrt TC, Wozniak C, Jones D, Trevett A.

Infect Immun. 2003 Dec;71(12):6962-70.


Molecular mechanisms regulating persistent Mycobacterium tuberculosis infection.

Zahrt TC.

Microbes Infect. 2003 Feb;5(2):159-67. Review.


Mycobacterium tuberculosis signal transduction system required for persistent infections.

Zahrt TC, Deretic V.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12706-11.


Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG.

Zahrt TC, Song J, Siple J, Deretic V.

Mol Microbiol. 2001 Mar;39(5):1174-85.


Effect of mutS and recD mutations on Salmonella virulence.

Zahrt TC, Buchmeier N, Maloy S.

Infect Immun. 1999 Nov;67(11):6168-72.


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