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Nuclear Receptors Database Including Negative Data (NR-DBIND): A Database Dedicated to Nuclear Receptors Binding Data Including Negative Data and Pharmacological Profile.

Réau M, Lagarde N, Zagury JF, Montes M.

J Med Chem. 2019 Mar 28;62(6):2894-2904. doi: 10.1021/acs.jmedchem.8b01105. Epub 2018 Nov 6.


CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability.

Montagne L, Derhourhi M, Piton A, Toussaint B, Durand E, Vaillant E, Thuillier D, Gaget S, De Graeve F, Rabearivelo I, Lansiaux A, Lenne B, Sukno S, Desailloud R, Cnop M, Nicolescu R, Cohen L, Zagury JF, Amouyal M, Weill J, Muller J, Sand O, Delobel B, Froguel P, Bonnefond A.

Mol Metab. 2018 Jul;13:1-9. doi: 10.1016/j.molmet.2018.05.005. Epub 2018 May 16.


A genome wide association study identifies new genes potentially associated with eyelid sagging.

Laville V, Le Clerc S, Ezzedine K, Jdid R, Taing L, Labib T, Coulonges C, Ulveling D, Galan P, Guinot C, Fezeu L, Morizot F, Latreille J, Malvy D, Tschachler E, Zagury JF.

Exp Dermatol. 2019 Aug;28(8):892-898. doi: 10.1111/exd.13559. Epub 2018 Jun 28.


Decoys Selection in Benchmarking Datasets: Overview and Perspectives.

Réau M, Langenfeld F, Zagury JF, Lagarde N, Montes M.

Front Pharmacol. 2018 Jan 24;9:11. doi: 10.3389/fphar.2018.00011. eCollection 2018. Review.


New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling.

Rayar AM, Lagarde N, Martin F, Blanchard F, Liagre B, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitía M.

Eur J Med Chem. 2018 Feb 25;146:577-587. doi: 10.1016/j.ejmech.2018.01.054. Epub 2018 Jan 31.


Genetic Associations with Spontaneous Preterm Birth.

Gérardin P, Coulonges C, Zagury JF.

N Engl J Med. 2017 Dec 14;377(24):2401. doi: 10.1056/NEJMc1713902. No abstract available.


Predicting the affinity of Farnesoid X Receptor ligands through a hierarchical ranking protocol: a D3R Grand Challenge 2 case study.

Réau M, Langenfeld F, Zagury JF, Montes M.

J Comput Aided Mol Des. 2018 Jan;32(1):231-238. doi: 10.1007/s10822-017-0063-0. Epub 2017 Sep 14.


Update on COX-2 Selective Inhibitors: Chemical Classification, Side Effects and their Use in Cancers and Neuronal Diseases.

Rayar AM, Lagarde N, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitia M.

Curr Top Med Chem. 2017;17(26):2935-2956. doi: 10.2174/1568026617666170821124947. Review.


HLA-check: evaluating HLA data from SNP information.

Jeanmougin M, Noirel J, Coulonges C, Zagury JF.

BMC Bioinformatics. 2017 Jul 11;18(1):334. doi: 10.1186/s12859-017-1746-1.


Discriminating Agonist from Antagonist Ligands of the Nuclear Receptors Using Different Chemoinformatics Approaches.

Lagarde N, Delahaye S, Jérémie A, Ben Nasr N, Guillemain H, Empereur-Mot C, Laville V, Labib T, Réau M, Langenfeld F, Zagury JF, Montes M.

Mol Inform. 2017 Oct;36(10). doi: 10.1002/minf.201700020. Epub 2017 Jul 3.


Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening.

Mouhsine H, Guillemain H, Moreau G, Fourati N, Zerrouki C, Baron B, Desallais L, Gizzi P, Ben Nasr N, Perrier J, Ratsimandresy R, Spadoni JL, Do H, England P, Montes M, Zagury JF.

Sci Rep. 2017 Jun 13;7(1):3424. doi: 10.1038/s41598-017-03427-z.


IL-1 Vaccination Is Suitable for Treating Inflammatory Diseases.

Assier E, Bessis N, Zagury JF, Boissier MC.

Front Pharmacol. 2017 Jan 31;8:6. doi: 10.3389/fphar.2017.00006. eCollection 2017. No abstract available.


Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner.

Eckenfelder A, Ségéral E, Pinzón N, Ulveling D, Amadori C, Charpentier M, Nidelet S, Concordet JP, Zagury JF, Paillart JC, Berlioz-Torrent C, Seitz H, Emiliani S, Gallois-Montbrun S.

Nucleic Acids Res. 2017 Apr 20;45(7):4158-4173. doi: 10.1093/nar/gkw1289.


Screening Explorer-An Interactive Tool for the Analysis of Screening Results.

Empereur-Mot C, Zagury JF, Montes M.

J Chem Inf Model. 2016 Dec 27;56(12):2281-2286. doi: 10.1021/acs.jcim.6b00283. Epub 2016 Nov 22.


Response to the commentary on 'A genome-wide association study in Caucasian women suggests the involvement of HLA gene in the severity of facial solar lentigines'.

Laville V, Le Clerc S, Ezzedine K, Zagury JF.

Pigment Cell Melanoma Res. 2017 Jan;30(1):74-75. doi: 10.1111/pcmr.12552. Epub 2016 Nov 30. No abstract available.


A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

Ulveling D, Le Clerc S, Cobat A, Labib T, Noirel J, Laville V, Coulonges C, Carpentier W, Nalpas B, Heim MH, Poynard T, Cerny A, Pol S, Bochud PY, Dabis F, Theodorou I, Lévy Y, Salmon D, Abel L, Dominguez S, Zagury JF; HEPAVIH ANRS CO13 Cohort Study Group; Swiss Hepatitis C Cohort Study Group; French ANRS HC EP 26 Genoscan Study Group.

Hepatology. 2016 Nov;64(5):1462-1472. doi: 10.1002/hep.28695. Epub 2016 Jul 29.


Discriminating agonist and antagonist ligands of the nuclear receptors using 3D-pharmacophores.

Lagarde N, Delahaye S, Zagury JF, Montes M.

J Cheminform. 2016 Sep 6;8(1):43. doi: 10.1186/s13321-016-0154-2. eCollection 2016.


What's My Diagnosis? A Case Study Submitted by:.

Pertes RA, Zagury JG.

J N J Dent Assoc. 2016 Aug;87(2):16. No abstract available.


A genome-wide association study in Caucasian women suggests the involvement of HLA genes in the severity of facial solar lentigines.

Laville V, Clerc SL, Ezzedine K, Jdid R, Taing L, Labib T, Coulonges C, Ulveling D, Carpentier W, Galan P, Hercberg S, Morizot F, Latreille J, Malvy D, Tschachler E, Zagury JF.

Pigment Cell Melanoma Res. 2016 Sep;29(5):550-8. doi: 10.1111/pcmr.12502. Epub 2016 Aug 8.


Haplotype estimation for biobank-scale data sets.

O'Connell J, Sharp K, Shrine N, Wain L, Hall I, Tobin M, Zagury JF, Delaneau O, Marchini J.

Nat Genet. 2016 Jul;48(7):817-20. doi: 10.1038/ng.3583. Epub 2016 Jun 6.


Burning mouth syndrome: Current concepts.

Nasri-Heir C, Zagury JG, Thomas D, Ananthan S.

J Indian Prosthodont Soc. 2015 Oct-Dec;15(4):300-7. doi: 10.4103/0972-4052.171823. Review.


Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys.

Desallais L, Bouchez C, Mouhsine H, Moreau G, Ratsimandresy R, Montes M, Do H, Quintin-Colonna F, Zagury JF.

Sci Rep. 2016 Jan 19;6:19549. doi: 10.1038/srep19549.


Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior.

Cheng Y, Pardo M, Armini RS, Martinez A, Mouhsine H, Zagury JF, Jope RS, Beurel E.

Brain Behav Immun. 2016 Mar;53:207-222. doi: 10.1016/j.bbi.2015.12.012. Epub 2016 Jan 6.


Efficacy of regional nerve block in management of myofascial pain of masseteric origin.

Quek SY, Subramanian G, Patel J, Ananthan S, Zagury JG, Khan J.

Cranio. 2015 Oct;33(4):285-90. doi: 10.1080/08869634.2015.1097300. Epub 2015 Dec 29.


Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.

McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, Buchbinder S, Carrington MN, Cossarizza A, Dalmau J, De Luca A, Goedert JJ, Gurdasani D, Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, Poli G, Sandhu MS, Schuitemaker H, Shea PR, Theodorou I, Walker BD, Weintrob AC, Winkler CA, Wolinsky SM, Raychaudhuri S, Goldstein DB, Telenti A, de Bakker PI, Zagury JF, Fellay J.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14658-63. doi: 10.1073/pnas.1514867112. Epub 2015 Nov 9.


Predictiveness curves in virtual screening.

Empereur-Mot C, Guillemain H, Latouche A, Zagury JF, Viallon V, Montes M.

J Cheminform. 2015 Nov 4;7:52. doi: 10.1186/s13321-015-0100-8. eCollection 2015.


Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs.

Spadoni JL, Rucart P, Le Clerc S, van Manen D, Coulonges C, Ulveling D, Laville V, Labib T, Taing L, Delaneau O, Montes M, Schuitemaker H, Noirel J, Zagury JF.

PLoS One. 2015 Sep 14;10(9):e0136989. doi: 10.1371/journal.pone.0136989. eCollection 2015.


A double amino-acid change in the HLA-A peptide-binding groove is associated with response to psychotropic treatment in patients with schizophrenia.

Le Clerc S, Taing L, Fond G, Meary A, Llorca PM, Blanc O, Beaune P, Rajagopal K, Jamain S, Tamouza R, Zagury JF, Leboyer M.

Transl Psychiatry. 2015 Jul 28;5:e608. doi: 10.1038/tp.2015.97.


JASSA: a comprehensive tool for prediction of SUMOylation sites and SIMs.

Beauclair G, Bridier-Nahmias A, Zagury JF, Saïb A, Zamborlini A.

Bioinformatics. 2015 Nov 1;31(21):3483-91. doi: 10.1093/bioinformatics/btv403. Epub 2015 Jul 2.


Benchmarking Data Sets for the Evaluation of Virtual Ligand Screening Methods: Review and Perspectives.

Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2015 Jul 27;55(7):1297-307. doi: 10.1021/acs.jcim.5b00090. Epub 2015 Jun 18. Review.


ALDsuite: Dense marker MALD using principal components of ancestral linkage disequilibrium.

Johnson RC, Nelson GW, Zagury JF, Winkler CA.

BMC Genet. 2015 Mar 7;16:23. doi: 10.1186/s12863-015-0179-y.


Udock, the interactive docking entertainment system.

Levieux G, Tiger G, Mader S, Zagury JF, Natkin S, Montes M.

Faraday Discuss. 2014;169:425-41. doi: 10.1039/c3fd00147d. Epub 2014 May 22.


Importance of the pharmacological profile of the bound ligand in enrichment on nuclear receptors: toward the use of experimentally validated decoy ligands.

Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2014 Oct 27;54(10):2915-44. doi: 10.1021/ci500305c. Epub 2014 Oct 9.


Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis.

Desallais L, Avouac J, Fréchet M, Elhai M, Ratsimandresy R, Montes M, Mouhsine H, Do H, Zagury JF, Allanore Y.

Arthritis Res Ther. 2014 Jul 24;16(4):R157. doi: 10.1186/ar4672.


Evidence after imputation for a role of MICA variants in nonprogression and elite control of HIV type 1 infection.

Le Clerc S, Delaneau O, Coulonges C, Spadoni JL, Labib T, Laville V, Ulveling D, Noirel J, Montes M, Schächter F, Caillat-Zucman S, Zagury JF.

J Infect Dis. 2014 Dec 15;210(12):1946-50. doi: 10.1093/infdis/jiu342. Epub 2014 Jun 16.


A general approach for haplotype phasing across the full spectrum of relatedness.

O'Connell J, Gurdasani D, Delaneau O, Pirastu N, Ulivi S, Cocca M, Traglia M, Huang J, Huffman JE, Rudan I, McQuillan R, Fraser RM, Campbell H, Polasek O, Asiki G, Ekoru K, Hayward C, Wright AF, Vitart V, Navarro P, Zagury JF, Wilson JF, Toniolo D, Gasparini P, Soranzo N, Sandhu MS, Marchini J.

PLoS Genet. 2014 Apr 17;10(4):e1004234. doi: 10.1371/journal.pgen.1004234. eCollection 2014 Apr.


NRLiSt BDB, the manually curated nuclear receptors ligands and structures benchmarking database.

Lagarde N, Ben Nasr N, Jérémie A, Guillemain H, Laville V, Labib T, Zagury JF, Montes M.

J Med Chem. 2014 Apr 10;57(7):3117-25. doi: 10.1021/jm500132p. Epub 2014 Mar 25.


Haplotype estimation using sequencing reads.

Delaneau O, Howie B, Cox AJ, Zagury JF, Marchini J.

Am J Hum Genet. 2013 Oct 3;93(4):687-96. doi: 10.1016/j.ajhg.2013.09.002.


Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.

McLaren PJ, Coulonges C, Ripke S, van den Berg L, Buchbinder S, Carrington M, Cossarizza A, Dalmau J, Deeks SG, Delaneau O, De Luca A, Goedert JJ, Haas D, Herbeck JT, Kathiresan S, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, O'Brien SJ, Pereyra F, Plummer FA, Poli G, Qi Y, Rucart P, Sandhu MS, Shea PR, Schuitemaker H, Theodorou I, Vannberg F, Veldink J, Walker BD, Weintrob A, Winkler CA, Wolinsky S, Telenti A, Goldstein DB, de Bakker PI, Zagury JF, Fellay J.

PLoS Pathog. 2013;9(7):e1003515. doi: 10.1371/journal.ppat.1003515. Epub 2013 Jul 25.


Immunogenetics: Genome-Wide Association of Non-Progressive HIV and Viral Load Control: HLA Genes and Beyond.

Limou S, Zagury JF.

Front Immunol. 2013 May 27;4:118. doi: 10.3389/fimmu.2013.00118. eCollection 2013.


DRAM triggers lysosomal membrane permeabilization and cell death in CD4(+) T cells infected with HIV.

Laforge M, Limou S, Harper F, Casartelli N, Rodrigues V, Silvestre R, Haloui H, Zagury JF, Senik A, Estaquier J.

PLoS Pathog. 2013;9(5):e1003328. doi: 10.1371/journal.ppat.1003328. Epub 2013 May 2.


Multiple structures for virtual ligand screening: defining binding site properties-based criteria to optimize the selection of the query.

Ben Nasr N, Guillemain H, Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2013 Feb 25;53(2):293-311. doi: 10.1021/ci3004557. Epub 2013 Jan 29.


Improved whole-chromosome phasing for disease and population genetic studies.

Delaneau O, Zagury JF, Marchini J.

Nat Methods. 2013 Jan;10(1):5-6. doi: 10.1038/nmeth.2307. No abstract available.


A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.

Le Clerc S, Taing L, Ezzedine K, Latreille J, Delaneau O, Labib T, Coulonges C, Bernard A, Melak S, Carpentier W, Malvy D, Jdid R, Galan P, Hercberg S, Morizot F, Guinot C, Tschachler E, Zagury JF.

J Invest Dermatol. 2013 Apr;133(4):929-35. doi: 10.1038/jid.2012.458. Epub 2012 Dec 6.


Haplotype inference.

Delaneau O, Zagury JF.

Methods Mol Biol. 2012;888:177-96. doi: 10.1007/978-1-61779-870-2_11.


Multicohort genomewide association study reveals a new signal of protection against HIV-1 acquisition.

Limou S, Delaneau O, van Manen D, An P, Sezgin E, Le Clerc S, Coulonges C, Troyer JL, Veldink JH, van den Berg LH, Spadoni JL, Taing L, Labib T, Montes M, Delfraissy JF, Schachter F, O'Brien SJ, Buchbinder S, van Natta ML, Jabs DA, Froguel P, Schuitemaker H, Winkler CA, Zagury JF.

J Infect Dis. 2012 Apr 1;205(7):1155-62. doi: 10.1093/infdis/jis028. Epub 2012 Feb 23.


Identification of IL7RA risk alleles for rapid progression during HIV-1 infection: a comprehensive study in the GRIV cohort.

Limou S, Melica G, Coulonges C, Lelièvre JD, Do H, McGinn S, Gut IG, Lévy Y, Zagury JF.

Curr HIV Res. 2012 Mar;10(2):143-50.


A linear complexity phasing method for thousands of genomes.

Delaneau O, Marchini J, Zagury JF.

Nat Methods. 2011 Dec 4;9(2):179-81. doi: 10.1038/nmeth.1785.


Active immunization against IL-23p19 improves experimental arthritis.

Ratsimandresy RA, Duvallet E, Assier E, Semerano L, Delavallée L, Bessis N, Zagury JF, Boissier MC.

Vaccine. 2011 Nov 21;29(50):9329-36. doi: 10.1016/j.vaccine.2011.09.134. Epub 2011 Oct 18.


Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course.

van Manen D, Delaneau O, Kootstra NA, Boeser-Nunnink BD, Limou S, Bol SM, Burger JA, Zwinderman AH, Moerland PD, van 't Slot R, Zagury JF, van 't Wout AB, Schuitemaker H.

PLoS One. 2011;6(7):e22208. doi: 10.1371/journal.pone.0022208. Epub 2011 Jul 21.

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