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Items: 1 to 50 of 215

1.

High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation.

de Souza Lima IM, Schiavinato JLDS, Paulino Leite SB, Sastre D, Bezerra HLO, Sangiorgi B, Corveloni AC, Thomé CH, Faça VM, Covas DT, Zago MA, Giacca M, Mano M, Panepucci RA.

Stem Cell Res Ther. 2019 Jul 8;10(1):202. doi: 10.1186/s13287-019-1318-6.

2.

Expression of cancer/testis antigens MAGE-A, MAGE-C1, GAGE and CTAG1B in benign and malignant thyroid diseases.

Melo DH, Mamede RCM, Neder L, Silva WA Jr, Barros-Filho MC, Kowalski LP, Pinto CAL, Zago MA, Figueiredo DLA, Jungbluth AA.

Oncol Lett. 2017 Dec;14(6):6485-6496. doi: 10.3892/ol.2017.7072. Epub 2017 Sep 26.

3.

Expression differences of genes in the PI3K/AKT, WNT/b-catenin, SHH, NOTCH and MAPK signaling pathways in CD34+ hematopoietic cells obtained from chronic phase patients with chronic myeloid leukemia and from healthy controls.

de Cássia Viu Carrara R, Fontes AM, Abraham KJ, Orellana MD, Haddad SK, Palma PVB, Panepucci RA, Zago MA, Covas DT.

Clin Transl Oncol. 2018 Apr;20(4):542-549. doi: 10.1007/s12094-017-1751-x. Epub 2017 Sep 13.

PMID:
28905209
4.

TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation.

Schiavinato JLDS, Haddad R, Saldanha-Araujo F, Baiochi J, Araujo AG, Santos Scheucher P, Covas DT, Zago MA, Panepucci RA.

Sci Rep. 2017 Jun 15;7(1):3627. doi: 10.1038/s41598-017-03456-8.

5.

MicroRNA-29 impairs the early phase of reprogramming process by targeting active DNA demethylation enzymes and Wnt signaling.

Fráguas MS, Eggenschwiler R, Hoepfner J, Schiavinato JL, Haddad R, Oliveira LH, Araújo AG, Zago MA, Panepucci RA, Cantz T.

Stem Cell Res. 2017 Mar;19:21-30. doi: 10.1016/j.scr.2016.12.020. Epub 2016 Dec 19.

6.

Impact of CTLA4 genotype and other immune response gene polymorphisms on outcomes after single umbilical cord blood transplantation.

Cunha R, Zago MA, Querol S, Volt F, Ruggeri A, Sanz G, Pouthier F, Kogler G, Vicario JL, Bergamaschi P, Saccardi R, Lamas CH, Díaz-de-Heredia C, Michel G, Bittencourt H, Tavella M, Panepucci RA, Fernandes F, Pavan J, Gluckman E, Rocha V; Eurocord, Cord Blood Committee Cellular Therapy–Immunobiology Working Party of the European Society for Blood and Marrow Transplantation, Netcord and Faculdade de Medicina de Ribeirão Preto–Faculdade de Medicina de São Paulo, Universidade de São Paulo.

Blood. 2017 Jan 26;129(4):525-532. doi: 10.1182/blood-2016-06-722249. Epub 2016 Nov 3.

PMID:
27811020
7.

TNF-alpha and Notch signaling regulates the expression of HOXB4 and GATA3 during early T lymphopoiesis.

Dos Santos Schiavinato JL, Oliveira LH, Araujo AG, Orellana MD, de Palma PV, Covas DT, Zago MA, Panepucci RA.

In Vitro Cell Dev Biol Anim. 2016 Oct;52(9):920-934. Epub 2016 Jun 1.

PMID:
27251160
8.

DSP30 enhances the immunosuppressive properties of mesenchymal stromal cells and protects their suppressive potential from lipopolysaccharide effects: A potential role of adenosine.

Sangiorgi B, De Freitas HT, Schiavinato JL, Leão V, Haddad R, Orellana MD, Faça VM, Ferreira GA, Covas DT, Zago MA, Panepucci RA.

Cytotherapy. 2016 Jul;18(7):846-59. doi: 10.1016/j.jcyt.2016.04.004.

PMID:
27260206
9.

Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample.

Brochado MJ, Gatti MF, Zago MA, Roselino AM.

Mem Inst Oswaldo Cruz. 2016 Feb;111(2):101-5. doi: 10.1590/0074-02760150326. Epub 2016 Jan 26.

10.

Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia.

Oliveira LH, Schiavinato JL, Fráguas MS, Lucena-Araujo AR, Haddad R, Araújo AG, Dalmazzo LF, Rego EM, Covas DT, Zago MA, Panepucci RA.

Cancer Sci. 2015 Oct;106(10):1264-77. doi: 10.1111/cas.12766. Epub 2015 Sep 21.

11.

Assessment of MLL methyltransferase gene expression in larynx carcinoma.

Figueiredo DL, do Amaral Rabello D, Zanette DL, Saggioro FP, Mamede RC, Zago MA, da Silva WA Jr, Saldanha-Araújo F, Pittella Silva F.

Oncol Rep. 2015 Apr;33(4):2017-22. doi: 10.3892/or.2015.3756. Epub 2015 Jan 28.

PMID:
25633166
12.

Genome-wide gene expression profiling reveals unsuspected molecular alterations in pemphigus foliaceus.

Malheiros D, Panepucci RA, Roselino AM, Araújo AG, Zago MA, Petzl-Erler ML.

Immunology. 2014 Nov;143(3):381-95. doi: 10.1111/imm.12315.

13.

NR3C1 polymorphisms in Brazilians of Caucasian, African, and Asian ancestry: glucocorticoid sensitivity and genotype association.

Souza MC, Martins CS, Silva-Junior IM, Chriguer RS, Bueno AC, Antonini SR, Silva WA Jr, Zago MA, Moreira AC, Castro Md.

Arq Bras Endocrinol Metabol. 2014 Feb;58(1):53-61.

PMID:
24728165
14.

Hydroxycarbamide modulates components involved in the regulation of adenosine levels in blood cells from sickle-cell anemia patients.

Silva-Pinto AC, Dias-Carlos C, Saldanha-Araujo F, Ferreira FI, Palma PV, Araujo AG, Queiroz RH, Elion J, Covas DT, Zago MA, Panepucci RA.

Ann Hematol. 2014 Sep;93(9):1457-65. doi: 10.1007/s00277-014-2066-4. Epub 2014 Apr 3.

PMID:
24696091
15.

Brief report: The lincRNA Hotair is required for epithelial-to-mesenchymal transition and stemness maintenance of cancer cell lines.

Pádua Alves C, Fonseca AS, Muys BR, de Barros E Lima Bueno R, Bürger MC, de Souza JE, Valente V, Zago MA, Silva WA Jr.

Stem Cells. 2013 Dec;31(12):2827-32. doi: 10.1002/stem.1547.

16.

Microarray profiles of ex vivo expanded hematopoietic stem cells show induction of genes involved in noncanonical Wnt signaling.

Zanette DL, Lorenzi JC, Panepucci RA, Santos AR, Molfetta GA, Araujo AG, Silva Junior WA, Zago MA.

Genet Mol Res. 2013 May 15;12(2):1691-7. doi: 10.4238/2013.May.15.1.

17.

Expression of calcium binding protein S100 A7 (psoriasin) in laryngeal carcinoma.

Tiveron RC, de Freitas LC, Figueiredo DL, Serafini LN, Mamede RC, Zago MA.

Braz J Otorhinolaryngol. 2012 Jul-Aug;78(4):59-65. English, Portuguese.

18.

The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets.

de Paula Careta F, Gobessi S, Panepucci RA, Bojnik E, Morato de Oliveira F, Mazza Matos D, Falcão RP, Laurenti L, Zago MA, Efremov DG.

Haematologica. 2012 Aug;97(8):1246-54. doi: 10.3324/haematol.2011.054668. Epub 2012 Feb 13.

19.

Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma.

Montoro JR, Mamede RC, Neder Serafini L, Saggioro FP, Figueiredo DL, Silva WA Jr, Jungbluth AA, Spagnoli GC, Zago MA.

Head Neck. 2012 Aug;34(8):1123-8. doi: 10.1002/hed.21880. Epub 2011 Nov 15.

PMID:
22083937
20.

Expression of human protein S100A7 (psoriasin), preparation of antibody and application to human larynx squamous cell carcinoma.

Barbieri MR, Andrade CD, Silva WA Jr, Marques AA, Leopoldino AM, Montes MB, Dias-Baruffi M, Soares IC, Wakamatsu A, Alves VA, Laure HJ, Zago MA, Greene LJ.

BMC Res Notes. 2011 Nov 14;4:494. doi: 10.1186/1756-0500-4-494.

21.

Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.

de Figueiredo-Pontes LL, Assis PA, Santana-Lemos BA, Jácomo RH, Lima AS, Garcia AB, Thomé CH, Araújo AG, Panepucci RA, Zago MA, Nagler A, Falcão RP, Rego EM.

PLoS One. 2011;6(10):e26713. doi: 10.1371/journal.pone.0026713. Epub 2011 Oct 28.

22.

Education, tobacco smoking, alcohol consumption, and IL-2 and IL-6 gene polymorphisms in the survival of head and neck cancer.

López RV, Zago MA, Eluf-Neto J, Curado MP, Daudt AW, da Silva-Junior WA, Zanette DL, Levi JE, de Carvalho MB, Kowalski LP, Abrahão M, de Góis-Filho JF, Boffetta P, Wünsch-Filho V.

Braz J Med Biol Res. 2011 Oct;44(10):1006-12. Epub 2011 Aug 12.

23.

Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling.

Saldanha-Araujo F, Haddad R, Farias KC, Souza Ade P, Palma PV, Araujo AG, Orellana MD, Voltarelli JC, Covas DT, Zago MA, Panepucci RA.

J Cell Mol Med. 2012 Jun;16(6):1232-44. doi: 10.1111/j.1582-4934.2011.01391.x.

24.

Inhibition of expression of HTLV-1 structural genes mediated by short hairpin RNA in vitro.

Haddad R, Kashima S, Rodrigues ES, Palma PV, Zago MA, Covas DT.

Anticancer Res. 2011 Jun;31(6):2173-7.

PMID:
21737637
25.

Insights on PRAME and osteosarcoma by means of gene expression profiling.

Toledo SR, Zago MA, Oliveira ID, Proto-Siqueira R, Okamoto OK, Severino P, Vêncio RZ, Gamba FT, Silva WA, Moreira-Filho CA, Torre CA, Alves MT, Garcia-Filho RJ, Simpson AJ, Petrilli AS.

J Orthop Sci. 2011 Jul;16(4):458-66. doi: 10.1007/s00776-011-0106-7. Epub 2011 Jun 21.

PMID:
21691740
26.

Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes.

Saldanha-Araujo F, Ferreira FI, Palma PV, Araujo AG, Queiroz RH, Covas DT, Zago MA, Panepucci RA.

Stem Cell Res. 2011 Jul;7(1):66-74. doi: 10.1016/j.scr.2011.04.001. Epub 2011 Apr 8.

27.

Constitutional telomerase mutations are genetic risk factors for cirrhosis.

Calado RT, Brudno J, Mehta P, Kovacs JJ, Wu C, Zago MA, Chanock SJ, Boyer TD, Young NS.

Hepatology. 2011 May;53(5):1600-7. doi: 10.1002/hep.24173.

28.

Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual.

Galante PA, Parmigiani RB, Zhao Q, Caballero OL, de Souza JE, Navarro FC, Gerber AL, Nicolás MF, Salim AC, Silva AP, Edsall L, Devalle S, Almeida LG, Ye Z, Kuan S, Pinheiro DG, Tojal I, Pedigoni RG, de Sousa RG, Oliveira TY, de Paula MG, Ohno-Machado L, Kirkness EF, Levy S, da Silva WA Jr, Vasconcelos AT, Ren B, Zago MA, Strausberg RL, Simpson AJ, de Souza SJ, Camargo AA.

Nucleic Acids Res. 2011 Aug;39(14):6056-68. doi: 10.1093/nar/gkr221. Epub 2011 Apr 14.

29.

Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9.

Paixão-Côrtes VR, Meyer D, Pereira TV, Mazières S, Elion J, Krishnamoorthy R, Zago MA, Silva WA Jr, Salzano FM, Bortolini MC.

PLoS One. 2011 Jan 27;6(1):e15656. doi: 10.1371/journal.pone.0015656.

30.

Silencing of HTLV-1 gag and env genes by small interfering RNAs in HEK 293 cells.

Haddad R, Kashima S, Rodrigues ES, Azevedo R, Palma PV, de Magalhães DA, Zago MA, Covas DT.

J Virol Methods. 2011 Apr;173(1):92-8. doi: 10.1016/j.jviromet.2011.01.012. Epub 2011 Jan 26.

PMID:
21277903
31.

Expression of MAGE-A4 and MAGE-C1 tumor-associated antigen in benign and malignant thyroid diseases.

Melo DH, Mamede RC, Neder L, Saggioro FP, Figueiredo DL, da Silva WA Jr, Jungbluth AA, Zago MA.

Head Neck. 2011 Oct;33(10):1426-32. doi: 10.1002/hed.21616. Epub 2011 Jan 18.

PMID:
21246638
32.

Cancer/Testis antigen expression on mesenchymal stem cells isolated from different tissues.

Saldanha-Araujo F, Haddad R, Zanette DL, De Araujo AG, Orellana MD, Covas DT, Zago MA, Panepucci RA.

Anticancer Res. 2010 Dec;30(12):5023-7.

PMID:
21187485
33.

Estimates of interethnic admixture in the Brazilian population using a panel of 24 X-linked insertion/deletion markers.

Resque RL, Freitas Ndo S, Rodrigues EM, Guerreiro JF, Santos NP, Ribeiro dos Santos A, Zago MA, Santos S.

Am J Hum Biol. 2010 Nov-Dec;22(6):849-52. doi: 10.1002/ajhb.21089.

PMID:
20865761
34.

BCR-ABL-mediated upregulation of PRAME is responsible for knocking down TRAIL in CML patients.

De Carvalho DD, Binato R, Pereira WO, Leroy JM, Colassanti MD, Proto-Siqueira R, Bueno-Da-Silva AE, Zago MA, Zanichelli MA, Abdelhay E, Castro FA, Jacysyn JF, Amarante-Mendes GP.

Oncogene. 2011 Jan 13;30(2):223-33. doi: 10.1038/onc.2010.409. Epub 2010 Sep 13.

PMID:
20838376
35.

Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy.

Andrade VC, Vettore AL, Panepucci RA, Almeida MS, Yamamoto M, De Carvalho F, Caballero OL, Zago MA, Colleoni GW.

Leuk Lymphoma. 2010 Aug;51(8):1543-9. doi: 10.3109/10428194.2010.491136.

PMID:
20528248
36.

Bone deposition, bone resorption, and osteosarcoma.

Toledo SR, Oliveira ID, Okamoto OK, Zago MA, de Seixas Alves MT, Filho RJ, Macedo CR, Petrilli AS.

J Orthop Res. 2010 Sep;28(9):1142-8. doi: 10.1002/jor.21120.

37.

Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel.

Santos NP, Ribeiro-Rodrigues EM, Ribeiro-Dos-Santos AK, Pereira R, Gusmão L, Amorim A, Guerreiro JF, Zago MA, Matte C, Hutz MH, Santos SE.

Hum Mutat. 2010 Feb;31(2):184-90. doi: 10.1002/humu.21159.

PMID:
19953531
38.

Increased levels of NOTCH1, NF-kappaB, and other interconnected transcription factors characterize primitive sets of hematopoietic stem cells.

Panepucci RA, Oliveira LH, Zanette DL, Viu Carrara Rde C, Araujo AG, Orellana MD, Bonini de Palma PV, Menezes CC, Covas DT, Zago MA.

Stem Cells Dev. 2010 Mar;19(3):321-32. doi: 10.1089/scd.2008.0397.

PMID:
19686049
39.

Expression of eight genes of nuclear factor-kappa B pathway in multiple myeloma using bone marrow aspirates obtained at diagnosis.

Sampaio MS, Vettore AL, Yamamoto M, Chauffaille Mde L, Zago MA, Colleoni GW.

Histol Histopathol. 2009 Aug;24(8):991-7. doi: 10.14670/HH-24.991.

PMID:
19554506
40.

Assessing interethnic admixture using an X-linked insertion-deletion multiplex.

Ribeiro-Rodrigues EM, dos Santos NP, dos Santos AK, Pereira R, Amorim A, Gusmão L, Zago MA, dos Santos SE.

Am J Hum Biol. 2009 Sep-Oct;21(5):707-9. doi: 10.1002/ajhb.20950.

PMID:
19533621
41.

A score system for quality evaluation of RNA sequence tags: an improvement for gene expression profiling.

Pinheiro DG, Galante PA, de Souza SJ, Zago MA, Silva WA Jr.

BMC Bioinformatics. 2009 Jun 6;10:170. doi: 10.1186/1471-2105-10-170.

42.

Frequency and prognostic relevance of cancer testis antigen 45 expression in multiple myeloma.

Andrade VC, Vettore AL, Regis Silva MR, Felix RS, Almeida MS, de Carvalho F, Zago MA, Caballero OL, Simpson AJ, Colleoni GW.

Exp Hematol. 2009 Apr;37(4):446-9. doi: 10.1016/j.exphem.2008.12.003. Epub 2009 Feb 10.

PMID:
19211183
43.

SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis.

Felix RS, Colleoni GW, Caballero OL, Yamamoto M, Almeida MS, Andrade VC, Chauffaille Mde L, Silva WA Jr, Begnami MD, Soares FA, Simpson AJ, Zago MA, Vettore AL.

Cancer Lett. 2009 Jun 8;278(1):41-8. doi: 10.1016/j.canlet.2008.12.022. Epub 2009 Jan 25.

PMID:
19171422
44.

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.

Calado RT, Regal JA, Hills M, Yewdell WT, Dalmazzo LF, Zago MA, Lansdorp PM, Hogge D, Chanock SJ, Estey EH, Falcão RP, Young NS.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1187-92. doi: 10.1073/pnas.0807057106. Epub 2009 Jan 15.

45.

Annexin A1 subcellular expression in laryngeal squamous cell carcinoma.

Alves VA, Nonogaki S, Cury PM, Wünsch-Filho V, de Carvalho MB, Michaluart-Júnior P, Moyses RA, Curioni OA, Figueiredo DL, Scapulatempo-Neto C, Parra ER, Polachini GM, Silistino-Souza R, Oliani SM, Silva-Júnior WA, Nobrega FG; Head and Neck Genome Project/GENCAPO, Tajara EH, Zago MA.

Histopathology. 2008 Dec;53(6):715-27. doi: 10.1111/j.1365-2559.2008.03186.x.

PMID:
19076685
46.

An INDEL polymorphism at the X-STR GATA172D05 flanking region.

Rodrigues EM, dos Santos NP, dos Santos AK, Marinho AN, Zago MA, Gomes I, Amorim A, Gusmão L, dos Santos SE.

Int J Legal Med. 2009 Jan;123(1):89-94. doi: 10.1007/s00414-008-0300-0. Epub 2008 Dec 2.

PMID:
19048268
47.

Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.

Rocha V, Porcher R, Fernandes JF, Filion A, Bittencourt H, Silva W Jr, Vilela G, Zanette DL, Ferry C, Larghero J, Devergie A, Ribaud P, Skvortsova Y, Tamouza R, Gluckman E, Socie G, Zago MA.

Leukemia. 2009 Mar;23(3):545-56. doi: 10.1038/leu.2008.323. Epub 2008 Nov 13.

PMID:
19005482
48.

SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.

Proto-Siqueira R, Panepucci RA, Careta FP, Lee A, Clear A, Morris K, Owen C, Rizzatti EG, Silva WA Jr, Falcão RP, Zago MA, Gribben JG.

Blood. 2008 Jul 15;112(2):394-7. doi: 10.1182/blood-2007-11-124065. Epub 2008 Apr 23.

49.

Mitochondrial population genomics supports a single pre-Clovis origin with a coastal route for the peopling of the Americas.

Fagundes NJ, Kanitz R, Eckert R, Valls AC, Bogo MR, Salzano FM, Smith DG, Silva WA Jr, Zago MA, Ribeiro-dos-Santos AK, Santos SE, Petzl-Erler ML, Bonatto SL.

Am J Hum Genet. 2008 Mar;82(3):583-92. doi: 10.1016/j.ajhg.2007.11.013. Epub 2008 Feb 28.

50.

Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts.

Covas DT, Panepucci RA, Fontes AM, Silva WA Jr, Orellana MD, Freitas MC, Neder L, Santos AR, Peres LC, Jamur MC, Zago MA.

Exp Hematol. 2008 May;36(5):642-54. doi: 10.1016/j.exphem.2007.12.015. Epub 2008 Mar 4.

PMID:
18295964

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