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Items: 18

1.

Adenine base editing in an adult mouse model of tyrosinaemia.

Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W.

Nat Biomed Eng. 2019 Feb 25. doi: 10.1038/s41551-019-0357-8. [Epub ahead of print]

PMID:
31740768
2.

Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition.

Schatoff EM, Goswami S, Zafra MP, Foronda M, Shusterman M, Leach BI, Katti A, Diaz BJ, Dow LE.

Cancer Discov. 2019 Oct;9(10):1358-1371. doi: 10.1158/2159-8290.CD-19-0289. Epub 2019 Jul 23.

PMID:
31337618
3.

Base editing the mammalian genome.

Schatoff EM, Zafra MP, Dow LE.

Methods. 2019 Jul 15;164-165:100-108. doi: 10.1016/j.ymeth.2019.02.022. Epub 2019 Mar 2. Review.

PMID:
30836137
4.

Optimized base editors enable efficient editing in cells, organoids and mice.

Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE.

Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3.

5.

R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.

Han T, Schatoff EM, Murphy C, Zafra MP, Wilkinson JE, Elemento O, Dow LE.

Nat Commun. 2017 Jul 11;8:15945. doi: 10.1038/ncomms15945.

6.

Mutation affecting the proximal promoter of Endoglin as the origin of hereditary hemorrhagic telangiectasia type 1.

Albiñana V, Zafra MP, Colau J, Zarrabeitia R, Recio-Poveda L, Olavarrieta L, Pérez-Pérez J, Botella LM.

BMC Med Genet. 2017 Feb 23;18(1):20. doi: 10.1186/s12881-017-0380-0.

7.

Asthma Due to Swiss Chard: Identification of a New Allergen.

Jara-Gutiérrez P, Zafra MP, Sanz V, Del Pozo V, Fernandez-Nieto M.

J Investig Allergol Clin Immunol. 2017;27(1):67-68. doi: 10.18176/jiaci.0120. No abstract available.

8.

Somatic Genome Editing Goes Viral.

Zafra MP, Dow LE.

Trends Mol Med. 2016 Oct;22(10):831-833. doi: 10.1016/j.molmed.2016.08.004. Epub 2016 Aug 20.

9.

SOCS3 silencing attenuates eosinophil functions in asthma patients.

Zafra MP, Cañas JA, Mazzeo C, Gámez C, Sanz V, Fernández-Nieto M, Quirce S, Barranco P, Ruiz-Hornillos J, Sastre J, del Pozo V.

Int J Mol Sci. 2015 Mar 10;16(3):5434-51. doi: 10.3390/ijms16035434.

10.

Exosome secretion by eosinophils: A possible role in asthma pathogenesis.

Mazzeo C, Cañas JA, Zafra MP, Rojas Marco A, Fernández-Nieto M, Sanz V, Mittelbrunn M, Izquierdo M, Baixaulli F, Sastre J, Del Pozo V.

J Allergy Clin Immunol. 2015 Jun;135(6):1603-13. doi: 10.1016/j.jaci.2014.11.026. Epub 2015 Jan 21.

PMID:
25617225
11.

Simulated gastrointestinal digestion reduces the allergic reactivity of shrimp extract proteins and tropomyosin.

Gámez C, Zafra MP, Sanz V, Mazzeo C, Ibáñez MD, Sastre J, del Pozo V.

Food Chem. 2015 Apr 15;173:475-81. doi: 10.1016/j.foodchem.2014.10.063. Epub 2014 Oct 22.

PMID:
25466048
12.

Allergy to short-acting β2-agonists in a COPD patient: Is an immunological mechanism involved?

Manso L, Valbuena T, Padial MA, Reche M, Zafra MP, Del Pozo V, Pascual CY.

Allergol Immunopathol (Madr). 2015 May-Jun;43(3):329-30. doi: 10.1016/j.aller.2014.04.003. Epub 2014 Aug 3. No abstract available.

PMID:
25097024
13.

Gene silencing of SOCS3 by siRNA intranasal delivery inhibits asthma phenotype in mice.

Zafra MP, Mazzeo C, Gámez C, Rodriguez Marco A, de Zulueta A, Sanz V, Bilbao I, Ruiz-Cabello J, Zubeldia JM, del Pozo V.

PLoS One. 2014 Mar 17;9(3):e91996. doi: 10.1371/journal.pone.0091996. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e105924.

14.

Acute generalized exanthematic pustulosis due to ibuprofen.

Arochena L, Zafra MP, Fariña MC, Del Pozo V, Fernández-Nieto M.

Ann Allergy Asthma Immunol. 2013 May;110(5):386-7. doi: 10.1016/j.anai.2013.01.020. Epub 2013 Feb 16. No abstract available.

PMID:
23622012
15.

Misregulation of suppressors of cytokine signaling in eosinophilic esophagitis.

Zafra MP, Cancelliere N, Rodríguez del Río P, Ruiz-García M, Estévez L, Andregnette V, Sánchez-García S, Fiandor A, Collantes E, Sastre J, Quirce S, Ibáñez MD, del Pozo V.

J Gastroenterol. 2013 Aug;48(8):910-20. doi: 10.1007/s00535-012-0723-8. Epub 2012 Dec 11.

PMID:
23229770
16.

Suppressors of cytokine signaling 3 expression in eosinophils: regulation by PGE₂ and Th2 cytokines.

López E, Zafra MP, Sastre B, Gámez C, Fernández-Nieto M, Sastre J, Lahoz C, Quirce S, Del Pozo V.

Clin Dev Immunol. 2011;2011:917015. doi: 10.1155/2011/917015. Epub 2011 Apr 27.

17.

Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes.

López E, Zafra MP, Sastre B, Gámez C, Lahoz C, del Pozo V.

Mediators Inflamm. 2011;2011:823279. doi: 10.1155/2011/823279. Epub 2011 Mar 20.

18.

Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278).

Acosta YY, Zafra MP, Ojeda G, Bernardone IS, Dianzani U, Portolés P, Rojo JM.

Cell Mol Life Sci. 2011 Sep;68(18):3065-79. doi: 10.1007/s00018-010-0606-1. Epub 2010 Dec 28.

PMID:
21188463

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