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Items: 14

1.

Design and Synthesis of New 1,3,5-Trisubstituted Triazines for the Treatment of Cancer and Inflammation.

Zacharie B, Abbott SD, Duceppe JS, Gagnon L, Grouix B, Geerts L, Gervais L, Sarra-Bournet F, Perron V, Wilb N, Penney CL, Laurin P.

ChemistryOpen. 2018 Sep 21;7(9):737-749. doi: 10.1002/open.201800136. eCollection 2018 Sep.

2.

A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.

Gagnon L, Leduc M, Thibodeau JF, Zhang MZ, Grouix B, Sarra-Bournet F, Gagnon W, Hince K, Tremblay M, Geerts L, Kennedy CRJ, H├ębert RL, Gutsol A, Holterman CE, Kamto E, Gervais L, Ouboudinar J, Richard J, Felton A, Laverdure A, Simard JC, L├ętourneau S, Cloutier MP, Leblond FA, Abbott SD, Penney C, Duceppe JS, Zacharie B, Dupuis J, Calderone A, Nguyen QT, Harris RC, Laurin P.

Am J Pathol. 2018 May;188(5):1132-1148. doi: 10.1016/j.ajpath.2018.01.009. Epub 2018 Feb 16.

3.

Synthesis and antimicrobial activity of 2-fluorophenyl-4,6-disubstituted [1,3,5]triazines.

Saleh M, Abbott S, Perron V, Lauzon C, Penney C, Zacharie B.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):945-9. doi: 10.1016/j.bmcl.2009.12.063. Epub 2009 Dec 23.

PMID:
20053565
4.

2,4,6-trisubstituted triazines as protein a mimetics for the treatment of autoimmune diseases.

Zacharie B, Abbott SD, Bienvenu JF, Cameron AD, Cloutier J, Duceppe JS, Ezzitouni A, Fortin D, Houde K, Lauzon C, Moreau N, Perron V, Wilb N, Asselin M, Doucet A, Fafard ME, Gaudreau D, Grouix B, Sarra-Bournet F, St-Amant N, Gagnon L, Penney CL.

J Med Chem. 2010 Feb 11;53(3):1138-45. doi: 10.1021/jm901403r.

PMID:
20047277
5.

2,6,9-Trisubstituted purine derivatives as protein A mimetics for the treatment of autoimmune diseases.

Zacharie B, Fortin D, Wilb N, Bienvenu JF, Asselin M, Grouix B, Penney C.

Bioorg Med Chem Lett. 2009 Jan 1;19(1):242-6. doi: 10.1016/j.bmcl.2008.10.116. Epub 2008 Oct 31.

PMID:
19010675
6.

Enhancement of Th1 type cytokine production and primary T cell activation by PBI-1393.

Allam M, Julien N, Zacharie B, Penney C, Gagnon L.

Clin Immunol. 2007 Dec;125(3):318-27. Epub 2007 Sep 12.

PMID:
17827067
7.

A mild procedure for the reduction of pyridine N-oxides to piperidines using ammonium formate.

Zacharie B, Moreau N, Dockendorff C.

J Org Chem. 2001 Jul 27;66(15):5264-5. No abstract available.

PMID:
11463286
8.

Immunostimulant oxidized beta-glucan conjugates.

Cross GG, Jennings HJ, Whitfield DM, Penney CL, Zacharie B, Gagnon L.

Int Immunopharmacol. 2001 Mar;1(3):539-50.

PMID:
11367537
9.

Synthesis and antiviral activities of N-9-oxypurine 1,3-dioxolane and 1,3-oxathiolane nucleosides.

Nguyen-Ba N, Lee N, Chan L, Zacharie B.

Bioorg Med Chem Lett. 2000 Oct 2;10(19):2223-6.

PMID:
11012034
10.

Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide.

Kadhim S, Penney C, Lagraoui M, Heibein J, Attardo G, Zacharie B, Connolly T, Gagnon L.

Int J Immunopharmacol. 2000 Sep;22(9):659-71.

PMID:
10884587
11.

D-LysAsnProTyr tetrapeptide: a novel B-cell stimulant and stabilized bursin mimetic.

Gagnon L, DiMarco M, Kirby R, Zacharie B, Penney CL.

Vaccine. 2000 Mar 17;18(18):1886-92.

PMID:
10699337
12.
13.

Synthesis and activity of dipeptides, linked to targeting ligands, as specific NK cell enhancers.

Abbott SD, Gagnon L, Lagraoui M, Kadhim S, Attardo G, Zacharie B, Penney CL.

J Med Chem. 1998 May 21;41(11):1909-26.

PMID:
9599240
14.

Synthesis and activity of 6-substituted purine linker amino acid immunostimulants.

Zacharie B, Gagnon L, Attardo G, Connolly TP, St-Denis Y, Penney CL.

J Med Chem. 1997 Aug 29;40(18):2883-94.

PMID:
9288170

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