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Items: 20

1.

Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial.

Alistar A, Morris BB, Desnoyer R, Klepin HD, Hosseinzadeh K, Clark C, Cameron A, Leyendecker J, D'Agostino R Jr, Topaloglu U, Boteju LW, Boteju AR, Shorr R, Zachar Z, Bingham PM, Ahmed T, Crane S, Shah R, Migliano JJ, Pardee TS, Miller L, Hawkins G, Jin G, Zhang W, Pasche B.

Lancet Oncol. 2017 Jun;18(6):770-778. doi: 10.1016/S1470-2045(17)30314-5. Epub 2017 May 8.

2.

Metabolic PET Imaging in Oncology.

Sai KKS, Zachar Z, Bingham PM, Mintz A.

AJR Am J Roentgenol. 2017 Aug;209(2):270-276. doi: 10.2214/AJR.17.18112. Epub 2017 May 2. Review.

PMID:
28463521
3.

Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy.

Bingham PM, Stuart SD, Zachar Z.

Expert Rev Clin Pharmacol. 2014 Nov;7(6):837-46. doi: 10.1586/17512433.2014.966816. Epub 2014 Oct 4. Review.

PMID:
25284345
4.

A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process.

Stuart SD, Schauble A, Gupta S, Kennedy AD, Keppler BR, Bingham PM, Zachar Z.

Cancer Metab. 2014 Mar 10;2(1):4. doi: 10.1186/2049-3002-2-4.

5.

Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.

Zachar Z, Marecek J, Maturo C, Gupta S, Stuart SD, Howell K, Schauble A, Lem J, Piramzadian A, Karnik S, Lee K, Rodriguez R, Shorr R, Bingham PM.

J Mol Med (Berl). 2011 Nov;89(11):1137-48. doi: 10.1007/s00109-011-0785-8. Epub 2011 Jul 19.

PMID:
21769686
6.
7.

Nuclear pre-mRNA metabolism: channels and tracks.

Kramer J, Zachar Z, Bingham PM.

Trends Cell Biol. 1994 Feb;4(2):35-7.

PMID:
14731863
8.

Looking at mRNA splicing and transport in situ.

Zachar Z, Kramer J, Bingham PM.

Methods Cell Biol. 1994;44:599-611. Review. No abstract available.

PMID:
7707971
9.

Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans.

Zachar Z, Kramer J, Mims IP, Bingham PM.

J Cell Biol. 1993 May;121(4):729-42.

10.

Suppressible insertion-induced mutations in Drosophila.

Zachar Z, Bingham PM.

Prog Nucleic Acid Res Mol Biol. 1989;36:87-98. Review. No abstract available.

PMID:
2544017
11.

On/off regulation of gene expression at the level of splicing.

Bingham PM, Chou TB, Mims I, Zachar Z.

Trends Genet. 1988 May;4(5):134-8. Review. No abstract available.

PMID:
2853467
12.

Evidence that a regulatory gene autoregulates splicing of its transcript.

Zachar Z, Chou TB, Bingham PM.

EMBO J. 1987 Dec 20;6(13):4105-11.

13.

Developmental expression of a regulatory gene is programmed at the level of splicing.

Chou TB, Zachar Z, Bingham PM.

EMBO J. 1987 Dec 20;6(13):4095-104.

14.

Molecular cloning and genetic analysis of the suppressor-of-white-apricot locus from Drosophila melanogaster.

Zachar Z, Garza D, Chou TB, Goland J, Bingham PM.

Mol Cell Biol. 1987 Jul;7(7):2498-505.

17.

On the molecular basis of transvection effects and the regulation of transcription.

Zachar Z, Chapman CH, Bingham PM.

Cold Spring Harb Symp Quant Biol. 1985;50:337-46. No abstract available.

PMID:
3868483
19.

Concanavalin A-mediated affinity film for Treponema pallidum.

Baseman JB, Zachar Z, Hayes NS.

Infect Immun. 1980 Jan;27(1):260-3.

20.

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