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Items: 13


Managing diabetic kidney disease.

Zac-Varghese S, Winocour P.

Br Med Bull. 2018 Mar 1;125(1):55-66. doi: 10.1093/bmb/ldx047.


Randomised clinical study: inulin short-chain fatty acid esters for targeted delivery of short-chain fatty acids to the human colon.

Polyviou T, MacDougall K, Chambers ES, Viardot A, Psichas A, Jawaid S, Harris HC, Edwards CA, Simpson L, Murphy KG, Zac-Varghese SE, Blundell JE, Dhillo WS, Bloom SR, Frost GS, Preston T, Tedford MC, Morrison DJ.

Aliment Pharmacol Ther. 2016 Oct;44(7):662-72. doi: 10.1111/apt.13749. Epub 2016 Jul 28.


Proglucagon Promoter Cre-Mediated AMPK Deletion in Mice Increases Circulating GLP-1 Levels and Oral Glucose Tolerance.

Sayers SR, Reimann F, Gribble FM, Parker H, Zac-Varghese S, Bloom SR, Foretz M, Viollet B, Rutter GA.

PLoS One. 2016 Mar 24;11(3):e0149549. doi: 10.1371/journal.pone.0149549. eCollection 2016.


Weight loss in a man from West Africa. S. stercoralis hyperinfection.

Topan R, James S, Mullish BH, Zac-Varghese S, Goldin RD, Thomas R, Cox J, Hoare JM.

Gut. 2015 Dec;64(12):1846, 1888. doi: 10.1136/gutjnl-2015-309308. Epub 2015 Mar 27. No abstract available.


Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.

Chambers ES, Viardot A, Psichas A, Morrison DJ, Murphy KG, Zac-Varghese SE, MacDougall K, Preston T, Tedford C, Finlayson GS, Blundell JE, Bell JD, Thomas EL, Mt-Isa S, Ashby D, Gibson GR, Kolida S, Dhillo WS, Bloom SR, Morley W, Clegg S, Frost G.

Gut. 2015 Nov;64(11):1744-54. doi: 10.1136/gutjnl-2014-307913. Epub 2014 Dec 10.


The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in mice.

Zac-Varghese S, Trapp S, Richards P, Sayers S, Sun G, Bloom SR, Reimann F, Gribble FM, Rutter GA.

Dis Model Mech. 2014 Nov;7(11):1275-86. doi: 10.1242/dmm.014720. Epub 2014 Sep 4.


A young fit man presenting to the emergency department with a painful neck due to a thyroid abscess.

Izzi-Engbeaya C, Zac-Varghese S, Palazzo F, Sanderson F, Meeran K, Dhillo WS.

QJM. 2013 Nov;106(11):1041-2. doi: 10.1093/qjmed/hct144. Epub 2013 Jul 3. No abstract available.


Adrenal venous sampling as a diagnostic procedure for primary hyperaldosteronism: experience from a tertiary referral centre.

Salem V, Hopkins TG, El-Gayar H, Zac-Varghese S, Goldstone AP, Todd JF, Dhillo W, Field BC, Martin N, Hatfield E, Donaldson M, Palazzo F, Meeran K, Jackson J, Tan T.

Hormones (Athens). 2012 Apr-Jun;11(2):151-9.


Translational studies on PYY as a novel target in obesity.

Zac-Varghese S, De Silva A, Bloom SR.

Curr Opin Pharmacol. 2011 Dec;11(6):582-5. doi: 10.1016/j.coph.2011.10.001. Epub 2011 Oct 21. Review.


Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420.

Tan TM, Field BC, Minnion JS, Cuenco-Shillito J, Chambers ES, Zac-Varghese S, Brindley CJ, Mt-Isa S, Fiorentino F, Ashby D, Ward I, Ghatei MA, Bloom SR.

Br J Clin Pharmacol. 2012 Feb;73(2):232-9. doi: 10.1111/j.1365-2125.2011.04082.x.


Hormonal interactions between gut and brain.

Zac-Varghese S, Tan T, Bloom SR.

Discov Med. 2010 Dec;10(55):543-52. Review.


The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy.

Nijher GM, Chaudhri OB, Ramachandran R, Murphy KG, Zac-Varghese SE, Fowler A, Chinthapalli K, Patterson M, Thompson EL, Williamson C, Kumar S, Ghatei MA, Bloom SR, Dhillo WS.

Br J Clin Pharmacol. 2010 Nov;70(5):674-81. doi: 10.1111/j.1365-2125.2010.03746.x.


Free fatty acid receptor 2 and nutrient sensing: a proposed role for fibre, fermentable carbohydrates and short-chain fatty acids in appetite regulation.

Sleeth ML, Thompson EL, Ford HE, Zac-Varghese SE, Frost G.

Nutr Res Rev. 2010 Jun;23(1):135-45. doi: 10.1017/S0954422410000089. Epub 2010 May 19. Review.


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