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Items: 19

1.

Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry.

Parsels LA, Tanska DM, Parsels JD, Zabludoff SD, Cuneo KC, Lawrence TS, Maybaum J, Morgan MA.

Cell Cycle. 2016;15(5):730-9. doi: 10.1080/15384101.2016.1148841.

2.

Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition.

Venkatesha VA, Parsels LA, Parsels JD, Zhao L, Zabludoff SD, Simeone DM, Maybaum J, Lawrence TS, Morgan MA.

Neoplasia. 2012 Jun;14(6):519-25.

3.

Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition.

Parsels LA, Qian Y, Tanska DM, Gross M, Zhao L, Hassan MC, Arumugarajah S, Parsels JD, Hylander-Gans L, Simeone DM, Morosini D, Brown JL, Zabludoff SD, Maybaum J, Lawrence TS, Morgan MA.

Clin Cancer Res. 2011 Jun 1;17(11):3706-15. doi: 10.1158/1078-0432.CCR-10-3082. Epub 2011 Apr 11.

4.

Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.

Morgan MA, Parsels LA, Zhao L, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Maybaum J, Lawrence TS.

Cancer Res. 2010 Jun 15;70(12):4972-81. doi: 10.1158/0008-5472.CAN-09-3573. Epub 2010 May 25.

5.

In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762.

Mitchell JB, Choudhuri R, Fabre K, Sowers AL, Citrin D, Zabludoff SD, Cook JA.

Clin Cancer Res. 2010 Apr 1;16(7):2076-84. doi: 10.1158/1078-0432.CCR-09-3277. Epub 2010 Mar 16.

6.

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies.

Zabludoff SD, Deng C, Grondine MR, Sheehy AM, Ashwell S, Caleb BL, Green S, Haye HR, Horn CL, Janetka JW, Liu D, Mouchet E, Ready S, Rosenthal JL, Queva C, Schwartz GK, Taylor KJ, Tse AN, Walker GE, White AM.

Mol Cancer Ther. 2008 Sep;7(9):2955-66. doi: 10.1158/1535-7163.MCT-08-0492.

7.

Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors.

Janetka JW, Almeida L, Ashwell S, Brassil PJ, Daly K, Deng C, Gero T, Glynn RE, Horn CL, Ioannidis S, Lyne P, Newcombe NJ, Oza VB, Pass M, Springer SK, Su M, Toader D, Vasbinder MM, Yu D, Yu Y, Zabludoff SD.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):4242-8. doi: 10.1016/j.bmcl.2008.05.016. Epub 2008 May 6.

PMID:
18547806
8.

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway.

Kung AL, Zabludoff SD, France DS, Freedman SJ, Tanner EA, Vieira A, Cornell-Kennon S, Lee J, Wang B, Wang J, Memmert K, Naegeli HU, Petersen F, Eck MJ, Bair KW, Wood AW, Livingston DM.

Cancer Cell. 2004 Jul;6(1):33-43.

9.

Male germ cells regulate transcription of the cathepsin l gene by rat Sertoli cells.

Zabludoff SD, Charron M, DeCerbo JN, Simukova N, Wright WW.

Endocrinology. 2001 Jun;142(6):2318-27.

PMID:
11356678
10.

p27Kip1 is expressed transiently in developing myotomes and enhances myogenesis.

Zabludoff SD, Csete M, Wagner R, Yu X, Wold BJ.

Cell Growth Differ. 1998 Jan;9(1):1-11.

11.

BRCA1 mRNA is expressed highly during meiosis and spermiogenesis but not during mitosis of male germ cells.

Zabludoff SD, Wright WW, Harshman K, Wold BJ.

Oncogene. 1996 Aug 1;13(3):649-53.

PMID:
8760307
12.
13.
14.

Cyclic protein-2, a secretory product of rat Sertoli cells, is the proenzyme form of cathepsin L.

Erickson-Lawrence M, Zabludoff SD, Wright WW.

Mol Endocrinol. 1991 Dec;5(12):1789-98.

PMID:
1791830
15.

Germ cell-Sertoli cell interactions: the effect of testicular maturation on the synthesis of cyclic protein-2 by rat Sertoli cells.

Zabludoff SD, Karzai AW, Wright WW.

Biol Reprod. 1990 Jul;43(1):25-33. Erratum in: Biol Reprod 1990 Sep;43(3):following 542.

PMID:
2393690
16.

Sertoli cells, proximal convoluted tubules in the kidney, and neurons in the brain contain cyclic protein-2.

Zabludoff SD, Erickson-Lawrence M, Wright WW.

Biol Reprod. 1990 Jul;43(1):15-24. Erratum in: Biol Reprod 1990 Sep;43(3):following 542.

PMID:
2393687
17.

Germ cell-Sertoli cell interactions. Studies of cyclic protein-2 in the seminiferous tubule.

Wright WW, Zabludoff SD, Erickson-Lawrence M, Karzai AW.

Ann N Y Acad Sci. 1989;564:173-85.

PMID:
2774415
18.

Serum hormone levels associated with spawning activity in the mummichog, Fundulus heteroclitus.

Cochran RC, Zabludoff SD, Paynter KT, DiMichele L, Palmer RE.

Gen Comp Endocrinol. 1988 May;70(2):345-54. Erratum in: Gen Comp Endocrinol 1988 Sep;71(3):533.

PMID:
3384313
19.

Foraging choice in laboratory rats: Constant vs. variable delay.

Zabludoff SD, Wecker J, Caraco T.

Behav Processes. 1988 Mar;16(1-2):95-110. doi: 10.1016/0376-6357(88)90021-6.

PMID:
24896407

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