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Items: 1 to 50 of 196

1.

Health tips for research groups.

Norris D, Dirnagl U, Zigmond MJ, Thompson-Peer K, Chow TT.

Nature. 2018 May;557(7705):302-304. doi: 10.1038/d41586-018-05146-5. No abstract available.

PMID:
29769687
2.

The Molecular Chaperone Hsc70 Interacts with Tyrosine Hydroxylase to Regulate Enzyme Activity and Synaptic Vesicle Localization.

Parra LA, Baust TB, Smith AD, Jaumotte JD, Zigmond MJ, Torres S, Leak RK, Pino JA, Torres GE.

J Biol Chem. 2016 Aug 19;291(34):17510-22. doi: 10.1074/jbc.M116.728782. Epub 2016 Jun 30.

3.

Protection of cultured dopamine neurons from MPP(+) requires a combination of neurotrophic factors.

Jaumotte JD, Wyrostek SL, Zigmond MJ.

Eur J Neurosci. 2016 Jul;44(1):1691-9. doi: 10.1111/ejn.13252. Epub 2016 May 21.

PMID:
27098376
4.

IGF-1 protects dopamine neurons against oxidative stress: association with changes in phosphokinases.

Ayadi AE, Zigmond MJ, Smith AD.

Exp Brain Res. 2016 Jul;234(7):1863-1873. doi: 10.1007/s00221-016-4572-1. Epub 2016 Feb 19.

5.

ERK1, 2, and 5 expression and activation in dopaminergic brain regions during postnatal development.

Parmar MS, Jaumotte JD, Zigmond MJ, Cavanaugh JE.

Int J Dev Neurosci. 2015 Nov;46:44-50. doi: 10.1016/j.ijdevneu.2015.06.009. Epub 2015 Aug 7.

PMID:
26363522
6.

Teaching responsible conduct responsibly.

Zigmond MJ, Fischer BA.

J Microbiol Biol Educ. 2014 Dec 15;15(2):83-7. doi: 10.1128/jmbe.v15i2.874. eCollection 2014 Dec. No abstract available.

7.

Introductory comments for the scientific ethics theme.

Fischer BA, Grinnell F, Zigmond MJ.

J Microbiol Biol Educ. 2014 Dec 15;15(2):82. doi: 10.1128/jmbe.v15i2.878. eCollection 2014 Dec. No abstract available.

8.

Comparison of GDF5 and GDNF as neuroprotective factors for postnatal dopamine neurons in ventral mesencephalic cultures.

Jaumotte JD, Zigmond MJ.

J Neurosci Res. 2014 Nov;92(11):1425-33. doi: 10.1002/jnr.23425. Epub 2014 Jun 11.

PMID:
24916473
9.

Role of ERK1, 2, and 5 in dopamine neuron survival during aging.

Parmar MS, Jaumotte JD, Wyrostek SL, Zigmond MJ, Cavanaugh JE.

Neurobiol Aging. 2014 Mar;35(3):669-79. doi: 10.1016/j.neurobiolaging.2013.09.031. Epub 2013 Oct 23.

10.

The interaction between stress and exercise, and its impact on brain function.

Russell VA, Zigmond MJ, Dimatelis JJ, Daniels WM, Mabandla MV.

Metab Brain Dis. 2014 Jun;29(2):255-60. doi: 10.1007/s11011-013-9479-y. Epub 2014 Jan 8. Review.

PMID:
24399497
11.

Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance.

Stetler RA, Leak RK, Gan Y, Li P, Zhang F, Hu X, Jing Z, Chen J, Zigmond MJ, Gao Y.

Prog Neurobiol. 2014 Mar;114:58-83. doi: 10.1016/j.pneurobio.2013.11.005. Epub 2014 Jan 2. Review.

12.

Exercise: is it a neuroprotective and if so, how does it work?

Zigmond MJ, Smeyne RJ.

Parkinsonism Relat Disord. 2014 Jan;20 Suppl 1:S123-7. doi: 10.1016/S1353-8020(13)70030-0. Review.

PMID:
24262162
13.

GST P1, a novel downstream regulator of LRRK2, G2019S-induced neuronal cell death.

Chen J, Liou A, Zhang L, Weng Z, Gao Y, Cao G, Zigmond MJ, Chen J.

Front Biosci (Elite Ed). 2012 Jun 1;4:2365-77.

14.

Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys.

Mitchell AC, Leak RK, Zigmond MJ, Cameron JL, Mirnics K.

Genomics. 2012 Mar;99(3):144-51. doi: 10.1016/j.ygeno.2011.12.006. Epub 2011 Dec 29.

15.

Neurorestoration by physical exercise: moving forward.

Zigmond MJ, Cameron JL, Hoffer BJ, Smeyne RJ.

Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S147-50. doi: 10.1016/S1353-8020(11)70046-3. Review.

PMID:
22166417
16.

Low concentrations of methamphetamine can protect dopaminergic cells against a larger oxidative stress injury: mechanistic study.

El Ayadi A, Zigmond MJ.

PLoS One. 2011;6(10):e24722. doi: 10.1371/journal.pone.0024722. Epub 2011 Oct 12.

17.

Physical activity-associated gene expression signature in nonhuman primate motor cortex.

Mitchell AC, Leak RK, Garbett K, Zigmond MJ, Cameron JL, Mirnics K.

Obesity (Silver Spring). 2012 Mar;20(3):692-8. doi: 10.1038/oby.2011.328. Epub 2011 Oct 20.

18.

Protective effects and mechanisms of sirtuins in the nervous system.

Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J.

Prog Neurobiol. 2011 Nov;95(3):373-95. doi: 10.1016/j.pneurobio.2011.09.001. Epub 2011 Sep 10. Review.

19.

Educational approaches for discouraging plagiarism.

Fischer BA, Zigmond MJ.

Urol Oncol. 2011 Jan-Feb;29(1):100-3. doi: 10.1016/j.urolonc.2010.11.014. Review.

PMID:
21194645
20.

L-DOPA reverses motor deficits associated with normal aging in mice.

Allen E, Carlson KM, Zigmond MJ, Cavanaugh JE.

Neurosci Lett. 2011 Feb 1;489(1):1-4. doi: 10.1016/j.neulet.2010.11.054. Epub 2010 Nov 25.

21.

The essential nature of sharing in science.

Fischer BA, Zigmond MJ.

Sci Eng Ethics. 2010 Dec;16(4):783-99. doi: 10.1007/s11948-010-9239-x. Epub 2010 Nov 25.

PMID:
21108019
22.

Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: time course of protection and neurorestoration.

Cohen AD, Zigmond MJ, Smith AD.

Brain Res. 2011 Jan 25;1370:80-8. doi: 10.1016/j.brainres.2010.11.006. Epub 2010 Nov 6.

23.

Assaying multiple biochemical variables from the same tissue sample.

Leak RK, Castro SL, Jaumotte JD, Smith AD, Zigmond MJ.

J Neurosci Methods. 2010 Aug 30;191(2):234-8. doi: 10.1016/j.jneumeth.2010.06.023. Epub 2010 Jun 30.

24.

Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency.

Zigmond MJ, Cameron JL, Leak RK, Mirnics K, Russell VA, Smeyne RJ, Smith AD.

Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S42-5. doi: 10.1016/S1353-8020(09)70778-3.

PMID:
20083005
25.

Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 1(7) glucocorticoid receptor promoter region.

Daniels WM, Fairbairn LR, van Tilburg G, McEvoy CR, Zigmond MJ, Russell VA, Stein DJ.

Metab Brain Dis. 2009 Dec;24(4):615-27. doi: 10.1007/s11011-009-9163-4. Epub 2009 Oct 9.

26.

Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway.

Liou AK, Leak RK, Li L, Zigmond MJ.

Neurobiol Dis. 2008 Oct;32(1):116-24. doi: 10.1016/j.nbd.2008.06.016. Epub 2008 Jul 8.

27.

Maternal separation exaggerates the toxic effects of 6-hydroxydopamine in rats: implications for neurodegenerative disorders.

Pienaar IS, Kellaway LA, Russell VA, Smith AD, Stein DJ, Zigmond MJ, Daniels WM.

Stress. 2008 Nov;11(6):448-56. doi: 10.1080/10253890801890721.

PMID:
18609296
28.

Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism.

Leak RK, Zigmond MJ, Liou AK.

J Neurochem. 2008 Jul;106(2):860-74. doi: 10.1111/j.1471-4159.2008.05459.x. Epub 2008 May 3.

29.
30.

Rapid activation of ERK by 6-hydroxydopamine promotes survival of dopaminergic cells.

Lin E, Cavanaugh JE, Leak RK, Perez RG, Zigmond MJ.

J Neurosci Res. 2008 Jan;86(1):108-17.

PMID:
17847117
31.

A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation.

Venneti S, Lopresti BJ, Wang G, Slagel SL, Mason NS, Mathis CA, Fischer ML, Larsen NJ, Mortimer AD, Hastings TG, Smith AD, Zigmond MJ, Suhara T, Higuchi M, Wiley CA.

J Neurochem. 2007 Sep;102(6):2118-2131. doi: 10.1111/j.1471-4159.2007.04690.x. Epub 2007 Jun 7.

32.
33.
34.

Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress.

Cavanaugh JE, Jaumotte JD, Lakoski JM, Zigmond MJ.

J Neurosci Res. 2006 Nov 1;84(6):1367-75.

PMID:
16941494
35.

Neurobiology of exercise.

Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, Van Hoomissen JD, Wade CE, York DA, Zigmond MJ.

Obesity (Silver Spring). 2006 Mar;14(3):345-56. Review.

36.

Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats.

Smith AD, Kozlowski DA, Bohn MC, Zigmond MJ.

Exp Neurol. 2005 Jun;193(2):420-6.

PMID:
15869944
37.

Dopaminergic innervation of forebrain by ventral mesencephalon in organotypic slice co-cultures: effects of GDNF.

Jaumotte JD, Zigmond MJ.

Brain Res Mol Brain Res. 2005 Mar 24;134(1):139-46.

PMID:
15790537
38.

Helping students get into graduate school.

Fischer BA, Zigmond MJ.

J Undergrad Neurosci Educ. 2004 Fall;3(1):A4-8. Epub 2004 Oct 15.

40.

Can the brain be protected through exercise? Lessons from an animal model of parkinsonism.

Smith AD, Zigmond MJ.

Exp Neurol. 2003 Nov;184(1):31-9. Review.

PMID:
14637076
41.

Effect of 6-hydroxydopamine on striatal GDNF and nigral GFRalpha1 and RET mRNAs in the adult rat.

Smith AD, Antion M, Zigmond MJ, Austin MC.

Brain Res Mol Brain Res. 2003 Oct 7;117(2):129-38.

PMID:
14559146
42.

Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK.

Ugarte SD, Lin E, Klann E, Zigmond MJ, Perez RG.

J Neurosci Res. 2003 Jul 1;73(1):105-12.

PMID:
12815714
43.

[3H]Dopamine release in striatum in response to cortical stimulation in a corticostriatal slice preparation.

Juranyi Z, Zigmond MJ, Harsing LG Jr.

J Neurosci Methods. 2003 Jun 15;126(1):57-67.

PMID:
12788502
45.

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF.

Cohen AD, Tillerson JL, Smith AD, Schallert T, Zigmond MJ.

J Neurochem. 2003 Apr;85(2):299-305.

46.

Stress-induced Parkinson's disease: a working hypothesis.

Smith AD, Castro SL, Zigmond MJ.

Physiol Behav. 2002 Dec;77(4-5):527-31. Review.

PMID:
12526994
47.

Increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity?

Zigmond MJ, Hastings TG, Perez RG.

Parkinsonism Relat Disord. 2002 Sep;8(6):389-93. Review.

PMID:
12217625
48.

Forced nonuse in unilateral parkinsonian rats exacerbates injury.

Tillerson JL, Cohen AD, Caudle WM, Zigmond MJ, Schallert T, Miller GW.

J Neurosci. 2002 Aug 1;22(15):6790-9.

49.
50.

Effect of bilateral 6-hydroxydopamine lesions of the medial forebrain bundle on reaction time.

Smith AD, Amalric M, Koob GF, Zigmond MJ.

Neuropsychopharmacology. 2002 Jun;26(6):756-64.

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