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Items: 1 to 50 of 70

1.

Commodity Chemicals From Engineered Modular Type I Polyketide Synthases.

Yuzawa S, Zargar A, Pang B, Katz L, Keasling JD.

Methods Enzymol. 2018;608:393-415. doi: 10.1016/bs.mie.2018.04.027. Epub 2018 May 26.

PMID:
30173771
2.

Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro.

Curran SC, Hagen A, Poust S, Chan LJG, Garabedian BM, de Rond T, Baluyot MJ, Vu JT, Lau AK, Yuzawa S, Petzold CJ, Katz L, Keasling JD.

ACS Chem Biol. 2018 Aug 17;13(8):2261-2268. doi: 10.1021/acschembio.8b00422. Epub 2018 Jun 26.

PMID:
29912551
3.

Roles of the apparent diffusion coefficient and tumor volume in predicting tumor grade in patients with choroid plexus tumors.

Sasaki T, Kim J, Moritani T, Capizzano AA, Sato SP, Sato Y, Kirby P, Ishitoya S, Oya A, Toda M, Yuzawa S, Takahashi K.

Neuroradiology. 2018 May;60(5):479-486. doi: 10.1007/s00234-018-2008-2. Epub 2018 Mar 15.

PMID:
29546484
4.

Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae.

Krink-Koutsoubelis N, Loechner AC, Lechner A, Link H, Denby CM, Vögeli B, Erb TJ, Yuzawa S, Jakociunas T, Katz L, Jensen MK, Sourjik V, Keasling JD.

ACS Synth Biol. 2018 Apr 20;7(4):1105-1115. doi: 10.1021/acssynbio.7b00466. Epub 2018 Mar 12.

5.

Synthetic biology of polyketide synthases.

Yuzawa S, Backman TWH, Keasling JD, Katz L.

J Ind Microbiol Biotechnol. 2018 Jul;45(7):621-633. doi: 10.1007/s10295-018-2021-9. Epub 2018 Feb 9.

6.

Heterologous Gene Expression of N-Terminally Truncated Variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular Polyketide Synthase.

Yuzawa S, Bailey CB, Fujii T, Jocic R, Barajas JF, Benites VT, Baidoo EEK, Chen Y, Petzold CJ, Katz L, Keasling JD.

ACS Chem Biol. 2017 Nov 17;12(11):2725-2729. doi: 10.1021/acschembio.7b00714. Epub 2017 Oct 17.

7.

Disseminated toxoplasmosis after hematopoietic stem cell transplantation showing unusual magnetic resonance images.

Tateno T, Onozawa M, Hashiguchi J, Ishio T, Yuzawa S, Matsuoka S, Kosugi-Kanaya M, Okada K, Shiratori S, Goto H, Kimura T, Sugita J, Nakagawa M, Hashimoto D, Kahata K, Fujimoto K, Endo T, Kondo T, Tanaka S, Hashino S, Teshima T.

Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12720. Epub 2017 Jun 20.

PMID:
28474756
8.

Ric-8A-mediated stabilization of the trimeric G protein subunit Gαi is inhibited by pertussis toxin-catalyzed ADP-ribosylation.

Chishiki K, Kamakura S, Hayase J, Yuzawa S, Sumimoto H.

Biochem Biophys Res Commun. 2017 Feb 12;483(3):941-945. doi: 10.1016/j.bbrc.2017.01.036. Epub 2017 Jan 10.

PMID:
28082199
9.

Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges.

Yuzawa S, Keasling JD, Katz L.

J Antibiot (Tokyo). 2017 Apr;70(4):378-385. doi: 10.1038/ja.2016.136. Epub 2016 Nov 16. Review.

PMID:
27847387
10.

A case of giant cell-rich solitary fibrous tumor in the external auditory canal.

Yuzawa S, Tanikawa S, Kunibe I, Nishihara H, Nagashima K, Tanaka S.

Pathol Int. 2016 Dec;66(12):701-705. doi: 10.1111/pin.12470. Epub 2016 Oct 6.

PMID:
27714938
11.

Genetic landscape of meningioma.

Yuzawa S, Nishihara H, Tanaka S.

Brain Tumor Pathol. 2016 Oct;33(4):237-247. Epub 2016 Sep 13. Review.

PMID:
27624470
12.

Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production.

Yuzawa S, Deng K, Wang G, Baidoo EE, Northen TR, Adams PD, Katz L, Keasling JD.

ACS Synth Biol. 2017 Jan 20;6(1):139-147. doi: 10.1021/acssynbio.6b00176. Epub 2016 Sep 6.

PMID:
27548700
13.

Insights into polyketide biosynthesis gained from repurposing antibiotic-producing polyketide synthases to produce fuels and chemicals.

Yuzawa S, Keasling JD, Katz L.

J Antibiot (Tokyo). 2016 Jul;69(7):494-9. doi: 10.1038/ja.2016.64. Epub 2016 Jun 1. Review.

14.

Clinical impact of targeted amplicon sequencing for meningioma as a practical clinical-sequencing system.

Yuzawa S, Nishihara H, Yamaguchi S, Mohri H, Wang L, Kimura T, Tsuda M, Tanino M, Kobayashi H, Terasaka S, Houkin K, Sato N, Tanaka S.

Mod Pathol. 2016 Jul;29(7):708-16. doi: 10.1038/modpathol.2016.81. Epub 2016 Apr 22.

15.

Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit.

Eng CH, Yuzawa S, Wang G, Baidoo EE, Katz L, Keasling JD.

Biochemistry. 2016 Mar 29;55(12):1677-80. doi: 10.1021/acs.biochem.6b00129. Epub 2016 Mar 15.

PMID:
26976746
16.

Analysis of NAB2-STAT6 Gene Fusion in 17 Cases of Meningeal Solitary Fibrous Tumor/Hemangiopericytoma: Review of the Literature.

Yuzawa S, Nishihara H, Wang L, Tsuda M, Kimura T, Tanino M, Tanaka S.

Am J Surg Pathol. 2016 Aug;40(8):1031-40. doi: 10.1097/PAS.0000000000000625. Review.

PMID:
26927892
17.

(18)F-fluoromisonidazole positron emission tomography can predict pathological necrosis of brain tumors.

Toyonaga T, Hirata K, Yamaguchi S, Hatanaka KC, Yuzawa S, Manabe O, Kobayashi K, Watanabe S, Shiga T, Terasaka S, Kobayashi H, Kuge Y, Tamaki N.

Eur J Nucl Med Mol Imaging. 2016 Jul;43(8):1469-76. doi: 10.1007/s00259-016-3320-x. Epub 2016 Feb 3.

PMID:
26841941
18.

RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells.

Maeda T, Yuzawa S, Suzuki A, Baba Y, Nishimura Y, Kato Y.

Int J Oncol. 2016 Mar;48(3):1251-7. doi: 10.3892/ijo.2016.3322. Epub 2016 Jan 5.

PMID:
26782071
19.

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study.

Yuzawa S, Nishihara H, Tanino M, Kimura T, Moriya J, Kamoshima Y, Nagashima K, Tanaka S.

Brain Tumor Pathol. 2016 Jan;33(1):63-70. doi: 10.1007/s10014-015-0241-5. Epub 2015 Nov 27.

PMID:
26614252
20.
21.

Deguelin induces apoptosis by targeting both EGFR-Akt and IGF1R-Akt pathways in head and neck squamous cell cancer cell lines.

Baba Y, Fujii M, Maeda T, Suzuki A, Yuzawa S, Kato Y.

Biomed Res Int. 2015;2015:657179. doi: 10.1155/2015/657179. Epub 2015 May 17.

22.

Mineral trioxide aggregate induces osteoblastogenesis via Atf6.

Maeda T, Suzuki A, Yuzawa S, Baba Y, Kimura Y, Kato Y.

Bone Rep. 2015 Apr 9;2:36-43. doi: 10.1016/j.bonr.2015.03.003. eCollection 2015 Jun.

23.

Giant annular purpuric eruption as a unique clinical manifestation of skin metastasis in apocrine carcinoma.

Yamaguchi Y, Kitamura S, Hata H, Imafuku K, Yuzawa S, Tanaka S, Shimizu H.

J Eur Acad Dermatol Venereol. 2016 Jun;30(6):1029-31. doi: 10.1111/jdv.13086. Epub 2015 Mar 9. No abstract available.

PMID:
25753374
24.

Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN.

Takayanagi H, Yuzawa S, Sumimoto H.

Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):175-83. doi: 10.1107/S2053230X14028143. Epub 2015 Jan 28.

25.

Structural basis of cofactor-mediated stabilization and substrate recognition of the α-tubulin acetyltransferase αTAT1.

Yuzawa S, Kamakura S, Hayase J, Sumimoto H.

Biochem J. 2015 Apr 1;467(1):103-13. doi: 10.1042/BJ20141193.

PMID:
25602620
26.

In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase.

Hagen A, Poust S, de Rond T, Yuzawa S, Katz L, Adams PD, Petzold CJ, Keasling JD.

Biochemistry. 2014 Sep 30;53(38):5975-7. doi: 10.1021/bi500951c. Epub 2014 Sep 16.

PMID:
25188840
27.

Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic α-lipomycin.

Yuzawa S, Eng CH, Katz L, Keasling JD.

J Antibiot (Tokyo). 2014 Feb;67(2):199-201. doi: 10.1038/ja.2013.110. Epub 2013 Oct 30. No abstract available.

PMID:
24169801
28.

Large solid-pseudopapillary neoplasm of the pancreas with aberrant protein expression and mutation of β-catenin: a case report and literature review of the distribution of β-catenin mutation.

Kobayashi T, Ozasa M, Miyashita K, Saga A, Miwa K, Saito M, Morioka M, Takeuchi M, Takenouchi N, Yabiku T, Kanno H, Yuzawa S, Tanino M, Tanaka S, Kawakami H, Asaka M, Sakamoto N.

Intern Med. 2013;52(18):2051-6. Review.

29.

Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase.

Yuzawa S, Eng CH, Katz L, Keasling JD.

Biochemistry. 2013 Jun 4;52(22):3791-3. doi: 10.1021/bi400520t. Epub 2013 May 23.

PMID:
23692164
30.

Ubiquitination of the heterotrimeric G protein α subunits Gαi2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A.

Chishiki K, Kamakura S, Yuzawa S, Hayase J, Sumimoto H.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):414-9. doi: 10.1016/j.bbrc.2013.04.103. Epub 2013 May 9.

PMID:
23665327
31.

Expression of CD163 prevents apoptosis through the production of granulocyte colony-stimulating factor in meningioma.

Kanno H, Nishihara H, Wang L, Yuzawa S, Kobayashi H, Tsuda M, Kimura T, Tanino M, Terasaka S, Tanaka S.

Neuro Oncol. 2013 Jul;15(7):853-64. doi: 10.1093/neuonc/not028. Epub 2013 Mar 28.

32.

Construction of a part of a 3-hydroxypropionate cycle for heterologous polyketide biosynthesis in Escherichia coli.

Yuzawa S, Chiba N, Katz L, Keasling JD.

Biochemistry. 2012 Dec 11;51(49):9779-81. doi: 10.1021/bi301414q. Epub 2012 Nov 28.

PMID:
23181847
33.

Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine.

Kato Y, Nishihara H, Yuzawa S, Mohri H, Kanno H, Hatanaka Y, Kimura T, Tanino M, Tanaka S.

Brain Tumor Pathol. 2013 Jul;30(3):167-74. doi: 10.1007/s10014-012-0124-y. Epub 2012 Nov 20. Erratum in: Brain Tumor Pathol. 2013 Oct;30(4):266-7.

PMID:
23180004
34.

Rh(III)-catalyzed C-H bond activation along with "rollover" for the synthesis of 4-azafluorenes.

Shibata T, Takayasu S, Yuzawa S, Otani T.

Org Lett. 2012 Oct 5;14(19):5106-9. doi: 10.1021/ol302375c. Epub 2012 Sep 17.

PMID:
22985424
35.

Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution.

Matsumoto S, Igura M, Nyirenda J, Matsumoto M, Yuzawa S, Noda N, Inagaki F, Kohda D.

Biochemistry. 2012 May 22;51(20):4157-66. doi: 10.1021/bi300076u. Epub 2012 May 14.

PMID:
22559858
36.

Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases.

Yuzawa S, Kapur S, Cane DE, Khosla C.

Biochemistry. 2012 May 8;51(18):3708-10. doi: 10.1021/bi300399u. Epub 2012 Apr 24.

37.

PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker.

Yuzawa S, Kano MR, Einama T, Nishihara H.

Med Oncol. 2012 Dec;29(4):2824-30. doi: 10.1007/s12032-012-0193-0. Epub 2012 Mar 9.

PMID:
22403002
38.

Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation.

Kapur S, Lowry B, Yuzawa S, Kenthirapalan S, Chen AY, Cane DE, Khosla C.

Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4110-5. doi: 10.1073/pnas.1118734109. Epub 2012 Feb 27.

39.

Heterologous production of polyketides by modular type I polyketide synthases in Escherichia coli.

Yuzawa S, Kim W, Katz L, Keasling JD.

Curr Opin Biotechnol. 2012 Oct;23(5):727-35. doi: 10.1016/j.copbio.2011.12.029. Epub 2012 Jan 13. Review.

PMID:
22244790
40.

Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN).

Yuzawa S, Kamakura S, Iwakiri Y, Hayase J, Sumimoto H.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19210-5. doi: 10.1073/pnas.1110951108. Epub 2011 Nov 10.

41.

Sublingual vaccination with fusion protein consisting of the functional domain of hemagglutinin A of Porphyromonas gingivalis and Escherichia coli maltose-binding protein elicits protective immunity in the oral cavity.

Yuzawa S, Kurita-Ochiai T, Hashizume T, Kobayashi R, Abiko Y, Yamamoto M.

FEMS Immunol Med Microbiol. 2012 Mar;64(2):265-72. doi: 10.1111/j.1574-695X.2011.00895.x.

42.
43.

A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.

Maehara Y, Miyano K, Yuzawa S, Akimoto R, Takeya R, Sumimoto H.

J Biol Chem. 2010 Oct 8;285(41):31435-45. doi: 10.1074/jbc.M110.161166. Epub 2010 Aug 2.

44.

The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.

Bae JH, Lew ED, Yuzawa S, Tomé F, Lax I, Schlessinger J.

Cell. 2009 Aug 7;138(3):514-24. doi: 10.1016/j.cell.2009.05.028.

45.

Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2.

Lulo J, Yuzawa S, Schlessinger J.

Biochem Biophys Res Commun. 2009 Jun 5;383(3):347-52. doi: 10.1016/j.bbrc.2009.04.011. Epub 2009 Apr 7.

PMID:
19358827
46.

The domain organization of p67 phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.

Yuzawa S, Miyano K, Honbou K, Inagaki F, Sumimoto H.

J Innate Immun. 2009;1(6):543-55. doi: 10.1159/000235656. Epub 2009 Aug 18.

47.
48.

Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor.

Ogura K, Shiga T, Yokochi M, Yuzawa S, Burke TR Jr, Inagaki F.

J Biomol NMR. 2008 Nov;42(3):197-207. doi: 10.1007/s10858-008-9272-0. Epub 2008 Oct 2.

49.

Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization.

Yang Y, Yuzawa S, Schlessinger J.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7681-6. doi: 10.1073/pnas.0802896105. Epub 2008 May 27.

50.

[Structural biology of receptor tyrosine kinase kit].

Yuzawa S, Schlessinger J.

Seikagaku. 2008 Feb;80(2):94-104. Review. Japanese. No abstract available.

PMID:
18341028

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